Development Level

Tclin 9 | 613
Tchem 4 | 1,598
Tbio 2 | 11,445

Collection

Ion Channel: IDG Consortium (T... 3 | 99

IMPC Phenotype

abnormal epididymis morphology 1 | 42
abnormal joint morphology 1 | 23
brachydactyly 1 | 19
decreased body weight 1 | 161
enlarged heart 1 | 210
increased lean body mass 1 | 172
increased startle reflex 1 | 112
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
syndactyly 1 | 23

Disease

Carcinoma 13 | 11,493
Nicotine dependence 12 | 54
Frontal lobe epilepsy 7 | 10
psoriasis 7 | 6,694
Seizures 6 | 596
Alcohol dependence 5 | 107
Alcoholic Intoxication, Chronic 5 | 289
Autosomal recessive predisposition 5 | 1,442
Blepharoptosis 5 | 231
Byzanthine arch palate 5 | 194
Cocaine Dependence 5 | 51
General anesthesia 5 | 53
Multiple pterygium syndrome 5 | 18
Muscle relaxation, function 5 | 8
Niacin deficiency 5 | 5
Nicotine Withdrawal Symptoms 5 | 5
Pellagra 5 | 26
Skeletal Muscle Relaxation for Endotracheal Intubation 5 | 5
Skeletal Muscle Relaxation for Endotracheal Intubation in C-Section 5 | 5
Smoking cessation assistance 5 | 8
TOBACCO ADDICTION, SUSCEPTIBILITY TO 5 | 12
TOBACCO ADDICTION, SUSCEPTIBILITY TO (finding) 5 | 12
adult high grade glioma 5 | 3,801
glioblastoma 5 | 5,792
Bell Palsy 4 | 58
Congenital Myasthenic Syndromes, Postsynaptic 4 | 11
Congenital myasthenic syndrome 4 | 25
Depressive disorder 4 | 409
Easy fatigability 4 | 18
Facial Paresis 4 | 59
Facial muscle weakness of muscles innervated by CN VII 4 | 58
Feeding difficulties 4 | 127
Lung Neoplasms 4 | 232
Mental Depression 4 | 333
Myasthenic Syndrome, Congenital, 1A, Slow-Channel 4 | 4
Myasthenic syndrome, congenital, postsynaptic slow-channel 4 | 4
Neonatal Hypotonia 4 | 64
Neuropathy 4 | 261
Ophthalmoplegia 4 | 106
Schizophrenia 4 | 1,160
Substance Withdrawal Syndrome 4 | 55
Tires quickly 4 | 18
atypical teratoid / rhabdoid tumor 4 | 5,112
lung cancer 4 | 4,740
lung carcinoma 4 | 2,843
medulloblastoma, large-cell 4 | 6,241
osteosarcoma 4 | 7,950
substance-related disorder 4 | 162
Akinesia 3 | 13
Aplasia of muscle 3 | 3
Arthrogryposis 3 | 54
Astrocytoma, Pilocytic 3 | 3,081
Autosomal dominant nocturnal frontal lobe epilepsy 3 | 4
Bipolar Disorder 3 | 666
Chronic obstructive pulmonary disease 3 | 184
Congenital Epicanthus 3 | 177
Congenital anomaly of face 3 | 56
Congenital hypoplasia of lung 3 | 48
Contracture 3 | 96
Contracture of joint 3 | 93
Cystic lymphangioma 3 | 19
Deglutition Disorders 3 | 132
Depressed nasal ridge 3 | 51
Distortion of face 3 | 46
Dysmorphic facies 3 | 46
Early severe fetal akinesia sequence 3 | 11
Edema 3 | 81
Epilepsy 3 | 792
Flexion contracture 3 | 93
Flexion contractures of joints 3 | 93
Funny looking face 3 | 46
Fused vertebrae 3 | 25
Hypertensive disorder 3 | 56
Hypoplastic finger 3 | 17
Hypoplastic mandible condyle 3 | 275
Increased susceptibility to fractures 3 | 21
Infantile onset 3 | 238
Intrauterine retardation 3 | 176
Long face 3 | 71
Low set ears 3 | 181
Lymphangioma, Cystic 3 | 21
MULTIPLE PTERYGIUM SYNDROME, LETHAL TYPE 3 | 5
Malignant hyperpyrexia due to anesthesia 3 | 10
Mandibular hypoplasia 3 | 275
Multiple pterygia 3 | 4
Myasthenic Syndrome, Congenital, Fast-Channel 3 | 3
Myasthenic Syndromes, Congenital 3 | 16
Neck muscle weakness 3 | 17
Pena-Shokeir syndrome type I 3 | 12
Polyhydramnios 3 | 108
Prenatal onset 3 | 139
Respiratory Insufficiency 3 | 132
Respiratory function loss 3 | 121
Short finger 3 | 17
Spinal fusion 3 | 25
Thin rib 3 | 21
Uranostaphyloschisis 3 | 167
Vertebral body fusion 3 | 25
facial deformity 3 | 46
pterygium 3 | 76

Tissue

Endocrine System 14 | 18,159
Nervous System 13 | 16,725
Blood and immune system 12 | 16,909
Female tissues 12 | 17,400
Male tissues 12 | 17,142
Skin and soft tissues 12 | 17,230
Digestive Tract 11 | 17,369
Liver and Pancreas 11 | 16,750
Urinary Tract 10 | 16,678
Respiratory system 9 | 16,393
Cardiovascular System 6 | 15,192

Target Family

Ion Channel 14 | 344
Non-IDG 1 | 12,091

Compartment GO Term

acetylcholine-gated channel co... 15 | 15
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuronal acetylcholine receptor subunit beta-2 CHRNB2 Tclin Ion Channel -1.62448 37.6 174
Acetylcholine receptor subunit alpha CHRNA1 Tclin Ion Channel -1.66400 41.7 307
Syntaxin-binding protein 5 STXBP5 Tbio Non-IDG -1.61049 45.3 34
Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 Tchem Ion Channel -1.31722 18.3 117
Neuronal acetylcholine receptor subunit beta-4 CHRNB4 Tclin Ion Channel -1.57182 33.7 130
Acetylcholine receptor subunit delta CHRND Tclin Ion Channel -1.30154 18.9 155
Acetylcholine receptor subunit beta CHRNB1 Tclin Ion Channel -1.26222 17.9 180
Neuronal acetylcholine receptor subunit alpha-5 CHRNA5 Tbio Ion Channel -2.15575 143.1 237
Neuronal acetylcholine receptor subunit alpha-6 CHRNA6 Tchem Ion Channel -1.19275 14.0 83
Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 Tclin Ion Channel -3.62589 4263.7 202