Development Level

Tbio 7 | 11,651
Tchem 6 | 1,388
Tclin 2 | 612

IMPC Phenotype

embryonic lethality prior to t... 2 | 278
preweaning lethality, complete... 2 | 979
abnormal gait 1 | 69
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 13 | 11,493
Obesity 11 | 678
Cancer 8 | 2,499
diabetes mellitus 8 | 1,728
Breast cancer 7 | 3,578
lung cancer 7 | 4,740
medulloblastoma, large-cell 7 | 6,241
psoriasis 7 | 6,694
Fatty liver disease 6 | 103
osteosarcoma 6 | 7,950
ovarian cancer 6 | 8,520
Autosomal recessive predisposition 5 | 1,442
Carcinoma, Hepatocellular 5 | 228
Heart failure 5 | 162
Hyperglycemia 5 | 137
Insulin Resistance 5 | 72
Lipid metabolism disorder 5 | 114
Liver carcinoma 5 | 240
interstitial cystitis 5 | 2,312
lung adenocarcinoma 5 | 2,716
malignant mesothelioma 5 | 3,232
non-small cell lung cancer 5 | 2,890
Atherosclerosis 4 | 291
Hyperinsulinism 4 | 133
Kidney cancer 4 | 2,613
Lipodystrophy 4 | 40
Multiple myeloma 4 | 1,332
Osteoporosis 4 | 363
ductal carcinoma in situ 4 | 1,745
ependymoma 4 | 4,679
glioblastoma 4 | 5,792
invasive ductal carcinoma 4 | 2,951
lung carcinoma 4 | 2,843
pituitary cancer 4 | 1,972
Alzheimer Disease 3 | 83
Alzheimer's disease 3 | 658
Astrocytoma, Pilocytic 3 | 3,081
Diabetes Mellitus, Experimental 3 | 108
Diabetes Mellitus, Non-Insulin-Dependent 3 | 145
Diabetes Mellitus, Type 2 3 | 142
Epilepsy 3 | 792
Hypertension 3 | 396
Hypertrophic Cardiomyopathy 3 | 117
Hypoglycemia 3 | 152
Intellectual disability 3 | 1,016
Liver disease 3 | 237
Polycystic ovary syndrome 3 | 360
Schizophrenia 3 | 1,160
Seizures 3 | 596
acute quadriplegic myopathy 3 | 1,158
astrocytoma 3 | 1,146
atypical teratoid / rhabdoid tumor 3 | 5,112
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
subependymal giant cell astrocytoma 3 | 2,287
Acromegaly 2 | 51
Acute kidney injury 2 | 70
Adenoma 2 | 167
Anemia 2 | 365
Anteverted nostril 2 | 191
Antiphospholipid syndrome 2 | 19
Arthritis 2 | 290
Arthritis, Rheumatoid 2 | 174
Bipolar Disorder 2 | 666
Blindness 2 | 88
Cerebrovascular disease 2 | 238
Coronary artery disease 2 | 268
Diarrhea 2 | 253
Endometrial cancer 2 | 311
Failure to gain weight 2 | 365
Heart disease 2 | 306
Hepatomegaly 2 | 285
Kidney disease 2 | 430
Liver Cirrhosis, Experimental 2 | 769
Liver cancer 2 | 604
Lung disease 2 | 142
Mammary Neoplasms 2 | 425
Melanoma 2 | 711
Methylmalonic acidemia 2 | 37
Myopathy 2 | 185
Parkinson's disease 2 | 392
Pediatric failure to thrive 2 | 365
Renal Insufficiency 2 | 90
Vascular disease 2 | 319
Vomiting 2 | 116
Waldenstrons macroglobulinemia 2 | 765
active ulcerative colitis 2 | 764
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
medulloblastoma 2 | 720
pediatric high grade glioma 2 | 1,064
primary Sjogren syndrome 2 | 735
ulcerative colitis 2 | 1,819

Tissue

Blood and immune system 15 | 16,909
Cardiovascular System 15 | 15,192
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678
Male tissues 14 | 17,142

Target Family

Enzyme 7 | 4,145
Non-IDG 5 | 12,091
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400
Transporter 1 | 473

Compartment GO Term

acetyl-CoA carboxylase complex 15 | 15
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Insulin INS Tbio Non-IDG -5.17849 146933.7 2197
Peroxisome proliferator-activated receptor gamma PPARG Tclin Nuclear Receptor -3.96393 9579.5 773
Solute carrier family 2, facilitated glucose transporter member 4 SLC2A4 Tbio Transporter -3.33806 2184.5 526
Fatty acid synthase FASN Tchem Enzyme -2.61118 400.6 468
Sterol regulatory element-binding protein 1 SREBF1 Tbio Transcription Factor -3.12075 1267.4 429
Acyl-CoA synthetase family member 3, mitochondrial ACSF3 Tbio Enzyme -1.06826 11.6 77
Diacylglycerol O-acyltransferase 1 DGAT1 Tclin Enzyme -2.74425 562.7 211
Bifunctional purine biosynthesis protein PURH ATIC Tchem Non-IDG -2.93014 835.0 246
Complement C1q tumor necrosis factor-related protein 1 C1QTNF1 Tbio Non-IDG -1.08523 19.9 213
ATP-citrate synthase ACLY Tchem Enzyme -2.82704 654.3 332