Development Level

Tbio 61 | 10,625
Tclin 10 | 602
Tchem 7 | 1,890
Tdark 7 | 7,003

Collection

Eligible Ion Channel Proteins 1 | 117

IMPC Term

preweaning lethality, complete... 7 | 633
decreased bone mineral content 4 | 157
decreased lean body mass 4 | 195
abnormal bone structure 2 | 131
abnormal retina morphology 2 | 100
decreased circulating choleste... 2 | 85
decreased circulating glucose ... 2 | 121
increased body weight 2 | 42
increased bone mineral density 2 | 52
abnormal behavior 1 | 226
abnormal bone mineralization 1 | 55
abnormal embryo size 1 | 112
abnormal lens morphology 1 | 73
abnormal retinal blood vessel ... 1 | 18
abnormal retinal outer nuclear... 1 | 5
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal thoracic vertebrae mo... 1 | 16
abnormal urinary bladder morph... 1 | 2
abnormal vocalization 1 | 21
cardiovascular system phenotyp... 1 | 35
decreased NK cell number 1 | 16
decreased T cell number 1 | 31
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating creatini... 1 | 31
decreased circulating free fat... 1 | 39
decreased circulating iron lev... 1 | 25
decreased circulating total pr... 1 | 41
decreased eosinophil cell numb... 1 | 41
decreased grip strength 1 | 123
decreased heart rate variabili... 1 | 11
decreased mature B cell number 1 | 25
decreased threshold for audito... 1 | 32
decreased vertical activity 1 | 22
embryonic lethality prior to t... 1 | 187
female infertility 1 | 34
hydrops fetalis 1 | 22
hyperactivity 1 | 108
hypoactivity 1 | 89
improved glucose tolerance 1 | 56
increased blood urea nitrogen ... 1 | 44
increased body length 1 | 20
increased exploration in new e... 1 | 56
increased grip strength 1 | 83
increased heart rate 1 | 17
increased heart weight 1 | 37
increased lean body mass 1 | 107
increased mean corpuscular vol... 1 | 91
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
increased vertical activity 1 | 18
male infertility 1 | 62
preweaning lethality, incomple... 1 | 260
short tibia 1 | 82
shortened PQ interval 1 | 6
shortened PR interval 1 | 5
shortened ST segment 1 | 9
thick ventricular wall 1 | 7
tremors 1 | 34

Disease

ovarian cancer 46 | 8,492
psoriasis 42 | 6,685
glioblastoma 37 | 5,572
medulloblastoma, large-cell 37 | 6,234
lung cancer 36 | 4,473
atypical teratoid / rhabdoid tumor 30 | 4,369
osteosarcoma 30 | 7,933
Carcinoma 28 | 2,147
colon cancer 27 | 1,475
invasive ductal carcinoma 27 | 2,950
non-small cell lung cancer 27 | 2,798
lung adenocarcinoma 26 | 2,714
pediatric high grade glioma 24 | 2,712
primitive neuroectodermal tumor 24 | 3,031
Breast cancer 23 | 3,099
lung carcinoma 23 | 2,844
pancreatic cancer 23 | 2,300
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,289
malignant mesothelioma 22 | 3,163
oligodendroglioma 22 | 2,849
pilocytic astrocytoma 22 | 3,086
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,988
Myopathy 19 | 128
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,956
Cardiomyopathy 17 | 110
acute quadriplegic myopathy 17 | 1,157
astrocytoma 15 | 1,493
Pick disease 14 | 1,893
astrocytic glioma 14 | 2,241
breast carcinoma 14 | 1,614
ductal carcinoma in situ 14 | 1,745
medulloblastoma 14 | 1,524
pituitary cancer 14 | 1,972
subependymal giant cell astrocytoma 14 | 2,287
Dilated cardiomyopathy 13 | 51
Familial isolated dilated cardiomyopathy 13 | 41
ependymoma 13 | 2,514
group 4 medulloblastoma 13 | 1,875
ulcerative colitis 13 | 2,087
adrenocortical carcinoma 12 | 1,427
posterior fossa group A ependymoma 12 | 1,511
primary pancreatic ductal adenocarcinoma 12 | 1,271
tuberculosis 12 | 1,563
adult high grade glioma 11 | 2,148
cystic fibrosis 11 | 1,670
posterior fossa group B ependymoma 11 | 1,530
sonic hedgehog group medulloblastoma 11 | 1,482
Cardiomyopathies 10 | 90
Kidney cancer 10 | 121
spina bifida 10 | 1,064
Atrial Fibrillation 9 | 110
Heart disease 9 | 279
active Crohn's disease 9 | 918
dermatomyositis 9 | 967
Amyotrophic Lateral Sclerosis 8 | 432
Hypertrophic Cardiomyopathy 8 | 56
atypical teratoid/rhabdoid tumor 8 | 1,095
nasopharyngeal carcinoma 8 | 1,056
Atopic dermatitis 7 | 944
Cancer 7 | 2,346
Cardiomyopathy, Dilated 7 | 47
Heart conduction disease 7 | 65
active ulcerative colitis 7 | 477
cutaneous lupus erythematosus 7 | 1,056
group 3 medulloblastoma 7 | 2,254
interstitial cystitis 7 | 2,299
juvenile dermatomyositis 7 | 1,189
limb-girdle muscular dystrophy 7 | 36
Duchenne muscular dystrophy 6 | 602
Long QT syndrome 6 | 53
Status Epilepticus 6 | 85
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 499
chronic rhinosinusitis 6 | 512
esophageal adenocarcinoma 6 | 737
gastric carcinoma 6 | 832
hereditary spastic paraplegia 6 | 313
Brugada syndrome 5 | 26
Cardiomyopathy, Hypertrophic, Familial 5 | 21
Down syndrome 5 | 548
Epilepsy 5 | 346
Intellectual disability 5 | 573
Renal Cell Carcinoma 5 | 199
aldosterone-producing adenoma 5 | 664
diabetes mellitus 5 | 1,663
glioblastoma multiforme 5 | 347
pancreatic carcinoma 5 | 567
Autistic Disorder 4 | 320
Dysuria 4 | 24
Malaria 4 | 140
Muscular dystrophy 4 | 48
Neuropathy 4 | 210
Rheumatoid Arthritis 4 | 1,171
Romano-Ward Syndrome 4 | 12
Schizophrenia 4 | 503
Spasticity 4 | 26
Urinary Tract Irritation 4 | 24
acute myeloid leukemia 4 | 785
chronic lymphocytic leukemia 4 | 244
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
progressive supranuclear palsy 4 | 674

Tissue

Cardiovascular System 85 | 17,958
Digestive Tract 85 | 18,473
Endocrine System 85 | 18,512
Female tissues 85 | 18,647
Liver and Pancreas 85 | 18,136
Male tissues 85 | 17,969
Nervous System 85 | 18,561
Respiratory system 85 | 17,484
Skin and soft tissues 85 | 18,115
Urinary Tract 85 | 18,444
Blood and immune system 84 | 17,995

Target Family

Non-IDG 55 | 11,969
Enzyme 12 | 4,146
Ion Channel 11 | 341
Kinase 3 | 634
Transporter 3 | 473
Epigenetic 1 | 242

Compartment GO Term

Z disc 85 | 85
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ankyrin-2 ANK2 Tbio Non-IDG -2.04838 107.1 205
Beta-parvin PARVB Tbio Non-IDG -1.23257 16.7 66
BAG family molecular chaperone regulator 3 BAG3 Tbio Non-IDG -2.19746 181.8 254
F-box and leucine-rich protein 22 FBXL22 Tdark Non-IDG 0.30 0.25 20
Sodium channel subunit beta-3 SCN3B Tbio Ion Channel -0.96474 9.44 51
Palladin PALLD Tbio Non-IDG -2.69516 485.5 162
Nesprin-2 SYNE2 Tbio Non-IDG -2.54881 337.2 32
Potassium voltage-gated channel subfamily E member 1 KCNE1 Tbio Ion Channel -2.65084 407.4 169
Myocardial zonula adherens protein POLR2M Tbio Non-IDG -1.84616 66.9 16
Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D Tclin Ion Channel -2.41920 256.9 205