Development Level

Tbio 12 | 11,445
Tchem 4 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

abnormal bone mineralization 1 | 38
abnormal eye anterior chamber ... 1 | 9
abnormal head morphology 1 | 10
abnormal kidney morphology 1 | 65
abnormal retinal outer nuclear... 1 | 3
abnormal seminal vesicle morph... 1 | 114
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
abnormal vitreous body morphol... 1 | 10
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
female infertility 1 | 60
increased bone mineral density 1 | 72
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
preweaning lethality, complete... 1 | 979
small testis 1 | 58

Disease

Carcinoma 16 | 11,493
Cancer 13 | 2,499
osteosarcoma 13 | 7,950
atypical teratoid / rhabdoid tumor 10 | 5,112
medulloblastoma, large-cell 9 | 6,241
ovarian cancer 9 | 8,520
psoriasis 9 | 6,694
glioblastoma 8 | 5,792
Kidney cancer 7 | 2,613
Breast cancer 6 | 3,578
Schizophrenia 6 | 1,160
adrenocortical carcinoma 6 | 1,428
ependymoma 6 | 4,679
group 3 medulloblastoma 6 | 4,104
Pick disease 5 | 1,894
interstitial cystitis 5 | 2,312
lung adenocarcinoma 5 | 2,716
oligodendroglioma 5 | 2,850
Liver cancer 4 | 604
Osteoporosis 4 | 363
Parkinson's disease 4 | 392
adult high grade glioma 4 | 3,801
diabetes mellitus 4 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung cancer 4 | 4,740
lung carcinoma 4 | 2,843
malignant mesothelioma 4 | 3,232
primitive neuroectodermal tumor 4 | 3,035
tuberculosis 4 | 2,010
Alzheimer's disease 3 | 658
Astrocytoma, Pilocytic 3 | 3,081
Carcinoma, Hepatocellular 3 | 228
Connective tissue disease 3 | 62
Crohn's disease 3 | 321
Endometrial cancer 3 | 311
Familial adenomatous polyposis 3 | 32
Hypoplastic mandible condyle 3 | 275
Increased hepatocellular carcinoma risk 3 | 27
Increased incidence of hepatocellular carcinoma 3 | 27
Intellectual disability 3 | 1,016
Large intestine cancer 3 | 126
Liver carcinoma 3 | 240
Lymphoma, Mantle-Cell 3 | 11
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse 3 | 12
Mandibular hypoplasia 3 | 275
Melanoma 3 | 711
Micrognathism 3 | 275
Micronodular cirrhosis 3 | 12
Prostatic Neoplasms 3 | 495
Renal Cell Carcinoma 3 | 214
Rheumatoid arthritis 3 | 1,191
Skin cancer 3 | 469
Somatic mutation 3 | 61
Subacute progressive viral hepatitis 3 | 9
breast carcinoma 3 | 1,638
hepatocellular carcinoma 3 | 547
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
medulloblastoma 3 | 720
non-small cell lung cancer 3 | 2,890
osteoporosis-pseudoglioma syndrome 3 | 9
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
spina bifida 3 | 1,074
Abdominal Pain 2 | 98
Abnormality of retinal pigmentation 2 | 111
Adenoma 2 | 167
Autistic Disorder 2 | 364
Big calvaria 2 | 147
Colonic Neoplasms 2 | 142
Colorectal Neoplasms 2 | 243
Dementia 2 | 175
Headache 2 | 37
High forehead 2 | 102
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Infantile onset 2 | 238
Liver neoplasms 2 | 130
Long philtrum 2 | 137
Lung Neoplasms 2 | 232
Malabsorption 2 | 82
Mesothelioma, Malignant 2 | 105
Muscular atrophy 2 | 71
Nerve Degeneration 2 | 121
Osteoarthritis 2 | 184
Pancreatic Neoplasm 2 | 85
Pancreatic Neoplasms 2 | 85
Retinal pigment epithelial abnormality 2 | 111
Stomach Neoplasms 2 | 300
Tall forehead 2 | 102
Toxic encephalopathy 2 | 141
Uterine Cervical Neoplasm 2 | 25
Uterine Cervical Neoplasms 2 | 26
Vascular disease 2 | 319
astrocytoma 2 | 1,146
colon cancer 2 | 1,478
pituitary cancer 2 | 1,972
posterior fossa group A ependymoma 2 | 468
subependymal giant cell astrocytoma 2 | 2,287

Tissue

Blood and immune system 16 | 16,909
Cardiovascular System 16 | 15,192
Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678
Respiratory system 15 | 16,393

Target Family

Non-IDG 13 | 12,091
GPCR 2 | 408
Kinase 2 | 634
Enzyme 1 | 4,145

Compartment GO Term

Wnt signalosome 18 | 18
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Putative segment polarity protein dishevelled homolog DVL1P1 DVL1P1 Tdark Non-IDG -2.11561 188.4 0
Low-density lipoprotein receptor-related protein 5 LRP5 Tbio Non-IDG -3.10429 1247.5 302
Transmembrane protein 59 TMEM59 Tbio Non-IDG -1.39364 21.4 55
Protein naked cuticle homolog 1 NKD1 Tbio Non-IDG -1.58873 38.5 99
Adenomatous polyposis coli protein APC Tbio Non-IDG -1.90646 66.5 508
Frizzled-1 FZD1 Tbio GPCR -2.07049 78.4 286
Leucine-rich repeat-containing G-protein coupled receptor 4 LGR4 Tbio GPCR -1.75604 72.2 230
E3 ubiquitin-protein ligase ZNRF3 ZNRF3 Tbio Enzyme -1.17415 16.1 57
Glycogen synthase kinase-3 beta GSK3B Tclin Kinase -3.00390 610.8 955
Axin-1 AXIN1 Tbio Non-IDG -2.52218 301.0 370