Development Level

Tbio 1,165 | 11,651
Tchem 162 | 1,388
Tdark 137 | 6,593
Tclin 84 | 612

Collection

RFA-RM-18-021 17 | 328
Ion Channel: IDG Consortium (T... 10 | 99
Kinase: IDG Consortium (Target... 4 | 125
GPCR: IDG Consortium (Complete... 3 | 25
GPCR: IDG Consortium (Targets) 3 | 126
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 105 | 979
preweaning lethality, incomple... 44 | 499
abnormal behavior 41 | 298
embryonic lethality prior to t... 34 | 278
decreased total body fat amoun... 27 | 207
embryonic lethality prior to o... 25 | 239
decreased body weight 24 | 161
decreased vertical activity 23 | 208
hypoactivity 21 | 132
abnormal bone structure 20 | 187
increased lean body mass 20 | 172
abnormal embryo size 19 | 220
hyperactivity 19 | 148
decreased bone mineral content 17 | 151
decreased bone mineral density 17 | 126
abnormal lens morphology 16 | 81
increased mean corpuscular hem... 16 | 96
enlarged heart 15 | 210
cataract 14 | 92
decreased circulating HDL chol... 14 | 68
decreased circulating choleste... 14 | 93
increased total body fat amoun... 14 | 134
abnormal sleep behavior 13 | 70
edema 13 | 59
increased circulating alkaline... 13 | 122
increased circulating sodium l... 13 | 71
abnormal heart morphology 12 | 162
decreased circulating serum al... 12 | 82
decreased grip strength 12 | 116
decreased lean body mass 12 | 135
increased mean corpuscular vol... 12 | 92
increased startle reflex 12 | 112
short tibia 12 | 97
abnormal seminal vesicle morph... 11 | 114
decreased circulating LDL chol... 11 | 38
decreased mean corpuscular vol... 11 | 79
decreased body length 10 | 101
decreased circulating glucose ... 10 | 126
decreased mean corpuscular hem... 10 | 50
increased bone mineral content 10 | 108
decreased lymphocyte cell numb... 9 | 83
decreased prepulse inhibition 9 | 82
increased bone mineral density 9 | 72
increased or absent threshold ... 9 | 101
small superior vagus ganglion 9 | 74
abnormal craniofacial morpholo... 8 | 33
abnormal eye morphology 8 | 68
abnormal gait 8 | 69
abnormal kidney morphology 8 | 65
decreased circulating total pr... 8 | 49
improved glucose tolerance 8 | 79
increased heart weight 8 | 62
thrombocytopenia 8 | 56
abnormal behavioral response t... 7 | 66
abnormal pericardium morpholog... 7 | 26
abnormal retina morphology 7 | 71
cardiovascular system phenotyp... 7 | 36
decreased circulating insulin ... 7 | 76
decreased circulating triglyce... 7 | 79
decreased leukocyte cell numbe... 7 | 73
embryonic growth retardation 7 | 106
hydrometra 7 | 53
impaired glucose tolerance 7 | 75
increased blood urea nitrogen ... 7 | 48
increased circulating chloride... 7 | 41
increased leukocyte cell numbe... 7 | 47
increased monocyte cell number 7 | 63
increased neutrophil cell numb... 7 | 46
persistence of hyaloid vascula... 7 | 33
prolonged QT interval 7 | 38
abnormal limb bud morphology 6 | 17
abnormal skin morphology 6 | 50
abnormal vibrissa morphology 6 | 25
decreased heart weight 6 | 27
decreased hemoglobin content 6 | 68
decreased startle reflex 6 | 75
increased circulating potassiu... 6 | 29
increased fasted circulating g... 6 | 76
prenatal lethality prior to he... 6 | 87
tremors 6 | 39
abnormal coat appearance 5 | 31
abnormal coat-hair pigmentatio... 5 | 64
abnormal epididymis morphology 5 | 42
abnormal neural tube closure 5 | 46
decreased blood urea nitrogen ... 5 | 51
decreased circulating alkaline... 5 | 46
decreased circulating calcium ... 5 | 36
decreased fasted circulating g... 5 | 65
enlarged lymph nodes 5 | 37
increased body weight 5 | 25
increased circulating bilirubi... 5 | 16
increased circulating calcium ... 5 | 34
increased circulating total pr... 5 | 28
increased circulating triglyce... 5 | 42
increased hemoglobin content 5 | 45
increased mean corpuscular hem... 5 | 36
limb grasping 5 | 41
male infertility 5 | 123
prenatal lethality 5 | 28
thrombocytosis 5 | 27

Disease

Carcinoma 956 | 11,493
ovarian cancer 829 | 8,520
osteosarcoma 717 | 7,950
psoriasis 629 | 6,694
medulloblastoma, large-cell 600 | 6,241
glioblastoma 599 | 5,792
lung cancer 477 | 4,740
atypical teratoid / rhabdoid tumor 476 | 5,112
ependymoma 438 | 4,679
Cancer 382 | 2,499
Astrocytoma, Pilocytic 363 | 3,081
lung carcinoma 353 | 2,843
adult high grade glioma 352 | 3,801
invasive ductal carcinoma 323 | 2,951
malignant mesothelioma 317 | 3,232
Breast cancer 315 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 313 | 3,291
group 3 medulloblastoma 307 | 4,104
non-small cell lung cancer 295 | 2,890
oligodendroglioma 290 | 2,850
intraductal papillary-mucinous adenoma (IPMA) 282 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 273 | 2,989
lung adenocarcinoma 273 | 2,716
diabetes mellitus 268 | 1,728
pancreatic cancer 267 | 2,398
tuberculosis 267 | 2,010
astrocytic glioma 266 | 2,597
subependymal giant cell astrocytoma 258 | 2,287
interstitial cystitis 250 | 2,312
primitive neuroectodermal tumor 247 | 3,035
Kidney cancer 231 | 2,613
pancreatic ductal adenocarcinoma liver metastasis 215 | 1,962
Pick disease 209 | 1,894
ulcerative colitis 202 | 1,819
Autosomal recessive predisposition 192 | 1,442
group 4 medulloblastoma 180 | 1,855
Rheumatoid arthritis 176 | 1,191
breast carcinoma 172 | 1,638
dermatomyositis 172 | 966
pituitary cancer 170 | 1,972
ductal carcinoma in situ 169 | 1,745
Multiple myeloma 167 | 1,332
cystic fibrosis 163 | 1,696
Schizophrenia 158 | 1,160
astrocytoma 150 | 1,146
juvenile dermatomyositis 148 | 1,187
cutaneous lupus erythematosus 146 | 1,057
acute quadriplegic myopathy 138 | 1,158
colon cancer 138 | 1,478
primary pancreatic ductal adenocarcinoma 136 | 1,109
pediatric high grade glioma 132 | 1,064
adrenocortical carcinoma 128 | 1,428
Alzheimer's disease 121 | 658
Liver Cirrhosis, Experimental 117 | 769
Epilepsy 106 | 792
gastric carcinoma 104 | 807
primary Sjogren syndrome 104 | 735
esophageal adenocarcinoma 103 | 737
Arthritis 102 | 290
active Crohn's disease 101 | 922
Hypersensitivity reaction type II disease 100 | 253
Intellectual disability 99 | 1,016
Multiple Sclerosis 99 | 540
spina bifida 98 | 1,074
Waldenstrons macroglobulinemia 96 | 765
mucosa-associated lymphoid tissue lymphoma 95 | 484
Kidney disease 90 | 430
Neurodegenerative disease 90 | 414
Bipolar Disorder 88 | 666
Duchenne muscular dystrophy 88 | 601
active ulcerative colitis 86 | 764
Obesity 83 | 678
Ankylosing spondylitis 81 | 140
Seizures 79 | 596
Melanoma 77 | 711
aldosterone-producing adenoma 76 | 665
non primary Sjogren syndrome sicca 76 | 891
Anemia 75 | 365
Down syndrome 74 | 499
Atopic dermatitis 73 | 952
Cognitive delay 73 | 608
Dull intelligence 73 | 645
Global developmental delay 73 | 608
Low intelligence 73 | 645
Mental Retardation 73 | 645
Mental and motor retardation 73 | 608
Mental deficiency 73 | 645
Poor school performance 73 | 645
Muscle hypotonia 72 | 571
Parkinson's disease 72 | 392
Acquired immunodeficiency syndrome 71 | 197
Behcet's disease 71 | 89
nasopharyngeal carcinoma 71 | 1,058
acute myeloid leukemia 70 | 783
Human immunodeficiency virus infectious disease 68 | 138
Prostatic Neoplasms 67 | 495
Uveitis 66 | 103
Juvenile rheumatoid arthritis 65 | 111
Short stature 64 | 531
autosomal dominant Emery-Dreifuss muscular dystrophy 64 | 510

Tissue

Endocrine System 1,442 | 18,159
Digestive Tract 1,424 | 17,369
Female tissues 1,420 | 17,400
Skin and soft tissues 1,416 | 17,230
Blood and immune system 1,406 | 16,909
Male tissues 1,406 | 17,142
Liver and Pancreas 1,403 | 16,750
Nervous System 1,397 | 16,725
Urinary Tract 1,394 | 16,678
Respiratory system 1,387 | 16,393
Cardiovascular System 1,317 | 15,192

Target Family

Non-IDG 980 | 12,091
Enzyme 319 | 4,145
Transporter 74 | 473
Kinase 73 | 634
Ion Channel 49 | 344
GPCR 34 | 408
Transcription Factor 9 | 1,400
Epigenetic 5 | 242
oGPCR 4 | 421
Nuclear Receptor 1 | 48

Compartment GO Term

Whole membrane 1,548 | 1,548
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.30856 210.6 116
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.33715 23.1 275
Ras-related protein Rab-22A RAB22A Tbio Enzyme -1.40824 19.7 123
Annexin A13 ANXA13 Tbio Non-IDG -1.19458 15.6 162
GTP-binding protein SAR1b SAR1B Tbio Enzyme -1.91051 79.7 184
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
ATP-binding cassette sub-family A member 1 ABCA1 Tclin Transporter -3.15111 1451.8 388
Protein disulfide-isomerase TMX3 TMX3 Tbio Enzyme -0.72922 5.29 80
HLA class I histocompatibility antigen, A-25 alpha chain HLA-A Tbio Non-IDG -2.41667 4123.8 0
UPF0577 protein KIAA1324 KIAA1324 Tbio Non-IDG -1.30268 19.8 137