Development Level

Tbio 937 | 10,625
Tchem 181 | 1,890
Tdark 139 | 7,003
Tclin 63 | 602

Collection

Ion Channel: IDG Consortium (Targets) 9 | 102
Kinase: IDG Consortium (Targets) 3 | 125
GPCR: IDG Consortium (Complete/Control) 1 | 24
GPCR: IDG Consortium (Targets) 1 | 128

IMPC Phenotype

preweaning lethality, complete... 58 | 633
abnormal behavior 27 | 226
decreased body weight 26 | 174
decreased total body fat amoun... 26 | 186
embryonic lethality prior to t... 20 | 187
decreased lean body mass 19 | 195
decreased grip strength 18 | 123
hypoactivity 18 | 89
increased mean corpuscular hem... 17 | 93
preweaning lethality, incomple... 17 | 260
decreased bone mineral content 15 | 157
decreased circulating HDL chol... 15 | 77
abnormal bone structure 14 | 131
decreased body length 14 | 108
decreased circulating choleste... 13 | 85
increased or absent threshold ... 13 | 128
decreased bone mineral density 12 | 126
decreased mean corpuscular vol... 12 | 50
embryonic lethality prior to o... 12 | 148
increased circulating alkaline... 12 | 119
abnormal lens morphology 10 | 73
abnormal sleep behavior 10 | 63
increased bone mineral content 10 | 92
increased circulating sodium l... 10 | 71
abnormal retinal pigmentation 9 | 61
decreased circulating glucose ... 9 | 121
decreased circulating triglyce... 9 | 83
decreased heart weight 9 | 44
decreased mean corpuscular hem... 9 | 34
decreased prepulse inhibition 9 | 52
hyperactivity 9 | 108
increased body weight 9 | 42
increased lean body mass 9 | 107
cardiovascular system phenotyp... 8 | 35
decreased circulating LDL chol... 8 | 37
decreased hemoglobin content 8 | 53
increased bone mineral density 8 | 52
short tibia 8 | 82
abnormal retina morphology 7 | 100
decreased circulating serum al... 7 | 79
decreased rib number 7 | 59
increased blood urea nitrogen ... 7 | 44
increased fasted circulating g... 7 | 68
increased mean corpuscular vol... 7 | 91
abnormal bone mineralization 6 | 55
abnormal embryo size 6 | 112
abnormal kidney morphology 6 | 30
abnormal limb bud morphology 6 | 15
decreased mean corpuscular hem... 6 | 19
decreased vertical activity 6 | 22
enlarged heart 6 | 111
impaired glucose tolerance 6 | 52
improved glucose tolerance 6 | 56
increased circulating chloride... 6 | 43
increased circulating potassiu... 6 | 31
increased grip strength 6 | 83
increased leukocyte cell numbe... 6 | 37
increased sacral vertebrae num... 6 | 62
thrombocytopenia 6 | 46
thrombocytosis 6 | 23
decreased circulating amylase ... 5 | 24
decreased circulating free fat... 5 | 39
decreased circulating insulin ... 5 | 75
decreased eosinophil cell numb... 5 | 41
decreased erythrocyte cell num... 5 | 43
decreased lumbar vertebrae num... 5 | 62
male infertility 5 | 62
persistence of hyaloid vascula... 5 | 22
abnormal behavioral response t... 4 | 52
abnormal body wall morphology 4 | 7
abnormal coat-hair pigmentatio... 4 | 54
abnormal epididymis morphology 4 | 31
abnormal eye morphology 4 | 38
abnormal eye size 4 | 11
abnormal femur morphology 4 | 14
abnormal tibia morphology 4 | 14
abnormal vertebrae morphology 4 | 14
cataract 4 | 26
corneal opacity 4 | 25
decreased blood urea nitrogen ... 4 | 31
decreased caudal vertebrae num... 4 | 49
decreased circulating calcium ... 4 | 33
decreased leukocyte cell numbe... 4 | 54
decreased total retina thickne... 4 | 20
edema 4 | 11
hemorrhage 4 | 12
increased circulating HDL chol... 4 | 63
increased circulating LDL chol... 4 | 15
increased circulating choleste... 4 | 53
increased circulating serum al... 4 | 25
increased erythrocyte cell num... 4 | 26
increased heart weight 4 | 37
increased hemoglobin content 4 | 45
increased rib number 4 | 41
increased startle reflex 4 | 38
increased total body fat amoun... 4 | 57
limb grasping 4 | 35
polydactyly 4 | 22
prenatal lethality prior to he... 4 | 64
decreased heart rate variabili... 3 | 11

Disease

ovarian cancer 741 | 8,491
osteosarcoma 592 | 7,933
psoriasis 533 | 6,685
medulloblastoma, large-cell 528 | 6,234
glioblastoma 501 | 5,572
lung cancer 374 | 4,473
atypical teratoid / rhabdoid tumor 367 | 4,369
Cancer 318 | 2,346
pilocytic astrocytoma 295 | 3,086
lung carcinoma 278 | 2,844
intraductal papillary-mucinous neoplasm (IPMN) 274 | 3,289
invasive ductal carcinoma 270 | 2,950
pediatric high grade glioma 258 | 2,712
oligodendroglioma 257 | 2,849
malignant mesothelioma 251 | 3,163
intraductal papillary-mucinous adenoma (IPMA) 238 | 2,956
diabetes mellitus 235 | 1,663
Breast cancer 229 | 3,098
intraductal papillary-mucinous carcinoma (IPMC) 228 | 2,988
pancreatic cancer 225 | 2,300
subependymal giant cell astrocytoma 225 | 2,287
primitive neuroectodermal tumor 220 | 3,031
non-small cell lung cancer 219 | 2,798
ependymoma 210 | 2,514
lung adenocarcinoma 209 | 2,714
Pick disease 196 | 1,893
astrocytic glioma 192 | 2,241
interstitial cystitis 187 | 2,299
ulcerative colitis 185 | 2,087
astrocytoma 182 | 1,493
pancreatic ductal adenocarcinoma liver metastasis 163 | 1,795
Carcinoma 160 | 2,147
tuberculosis 160 | 1,563
group 4 medulloblastoma 158 | 1,875
adult high grade glioma 154 | 2,148
Rheumatoid Arthritis 153 | 1,170
dermatomyositis 153 | 966
Multiple myeloma 152 | 1,327
pituitary cancer 152 | 1,972
posterior fossa group A ependymoma 143 | 1,511
ductal carcinoma in situ 142 | 1,745
breast carcinoma 141 | 1,614
primary pancreatic ductal adenocarcinoma 141 | 1,271
cystic fibrosis 136 | 1,670
juvenile dermatomyositis 132 | 1,189
group 3 medulloblastoma 125 | 2,254
medulloblastoma 122 | 1,524
acute quadriplegic myopathy 119 | 1,157
colon cancer 118 | 1,475
cutaneous lupus erythematosus 117 | 1,056
sonic hedgehog group medulloblastoma 114 | 1,482
adrenocortical carcinoma 111 | 1,427
Alzheimer's disease 103 | 644
posterior fossa group B ependymoma 102 | 1,530
Hypersensitivity reaction type II disease 91 | 235
primary Sjogren syndrome 91 | 788
gastric carcinoma 89 | 832
spina bifida 89 | 1,064
Arthritis 88 | 248
Neurodegenerative disease 86 | 383
esophageal adenocarcinoma 85 | 737
active Crohn's disease 84 | 918
atypical teratoid/rhabdoid tumor 83 | 1,095
Waldenstrons macroglobulinemia 80 | 764
Ankylosing spondylitis 79 | 138
Multiple Sclerosis 78 | 498
Kidney disease 76 | 397
Obesity 72 | 616
Duchenne muscular dystrophy 70 | 602
Schizophrenia 69 | 503
aldosterone-producing adenoma 69 | 664
Acquired immunodeficiency syndrome 68 | 164
Down syndrome 67 | 548
Uveitis 65 | 103
Juvenile rheumatoid arthritis 64 | 105
mucosa-associated lymphoid tissue lymphoma 64 | 480
Human immunodeficiency virus infectious disease 62 | 129
Parkinson's disease 62 | 364
progressive supranuclear palsy 60 | 674
Atopic dermatitis 59 | 944
IGA Glomerulonephritis 58 | 454
Behcet's disease 57 | 74
fibroadenoma 57 | 557
Stevens-Johnson syndrome 56 | 91
Psoriatic arthritis 55 | 85
non primary Sjogren syndrome sicca 55 | 840
pancreatic carcinoma 55 | 567
nasopharyngeal carcinoma 54 | 1,056
Anemia 53 | 252
Prostatic Neoplasms 53 | 471
acute myeloid leukemia 53 | 785
Liver disease 51 | 219
autosomal dominant Emery-Dreifuss muscular dystrophy 51 | 499
hereditary spastic paraplegia 48 | 313
tuberculosis and treatment for 6 months 48 | 686
Epilepsy 47 | 346
active ulcerative colitis 47 | 477
Dermatitis 46 | 141
Hypertension 46 | 293
Intellectual disability 45 | 573

Tissue

Nervous System 1,241 | 18,560
Digestive Tract 1,239 | 18,472
Liver and Pancreas 1,238 | 18,135
Endocrine System 1,237 | 18,511
Female tissues 1,237 | 18,646
Urinary Tract 1,236 | 18,443
Cardiovascular System 1,233 | 17,957
Blood and immune system 1,230 | 17,994
Male tissues 1,229 | 17,968
Respiratory system 1,222 | 17,483
Skin and soft tissues 1,220 | 18,114

Target Family

Non-IDG 846 | 11,969
Enzyme 268 | 4,146
Kinase 68 | 634
Transporter 67 | 473
Ion Channel 40 | 341
GPCR 17 | 408
Transcription Factor 8 | 1,400
Epigenetic 5 | 242
Nuclear Receptor 1 | 48

Compartment GO Term

Whole membrane 1,320 | 1,320
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Epithelial membrane protein 2 EMP2 Tbio Non-IDG -2.29593 203.1 88
E-selectin SELE Tchem Non-IDG -3.43650 2598.8 820
WD repeat-containing protein mio MIOS Tdark Non-IDG -1.44864 27.4 14
Long-chain-fatty-acid--CoA ligase 6 ACSL6 Tbio Enzyme -1.84683 72.3 120
Interferon-induced transmembrane protein 3 IFITM3 Tbio Non-IDG -1.87958 126.0 172
Receptor tyrosine-protein kinase erbB-2 ERBB2 Tclin Kinase -4.25806 19000.3 3336
Proto-oncogene Wnt-1 WNT1 Tbio Non-IDG -2.73870 492.7 294
Adaptin ear-binding coat-associated protein 2 NECAP2 Tdark Non-IDG 0.03 1.26 31
High affinity nerve growth factor receptor NTRK1 Tchem Kinase -3.03552 1003.4 1000
Alpha-soluble NSF attachment protein NAPA Tbio Non-IDG -1.91708 86.7 133