Development Level

Tbio 1,034 | 11,445
Tdark 391 | 6,588
Tchem 145 | 1,598
Tclin 43 | 613

Collection

RFA-RM-18-021 24 | 328
Kinase: IDG Consortium (Target... 12 | 125
Ion Channel: IDG Consortium (T... 7 | 99
GPCR: IDG Consortium (Targets) 5 | 126
Kinase: IDG Consortium (Comple... 3 | 37
GPCR: IDG Consortium (Complete... 2 | 25

IMPC Phenotype

preweaning lethality, complete... 80 | 979
preweaning lethality, incomple... 42 | 499
enlarged heart 26 | 210
abnormal behavior 23 | 298
embryonic lethality prior to t... 23 | 278
abnormal embryo size 21 | 220
decreased total body fat amoun... 20 | 207
abnormal seminal vesicle morph... 18 | 114
decreased body weight 17 | 161
decreased vertical activity 17 | 208
abnormal heart morphology 16 | 162
embryonic lethality prior to o... 16 | 239
increased or absent threshold ... 16 | 101
decreased bone mineral density 15 | 126
increased circulating alkaline... 15 | 122
increased lean body mass 15 | 172
decreased bone mineral content 13 | 151
decreased leukocyte cell numbe... 13 | 73
increased total body fat amoun... 13 | 134
short tibia 13 | 97
decreased grip strength 12 | 116
abnormal bone structure 11 | 187
abnormal eye morphology 11 | 68
impaired glucose tolerance 11 | 75
improved glucose tolerance 11 | 79
increased mean corpuscular hem... 11 | 96
decreased circulating triglyce... 10 | 79
decreased lymphocyte cell numb... 10 | 83
decreased mean corpuscular vol... 10 | 79
increased bone mineral content 10 | 108
abnormal epididymis morphology 9 | 42
abnormal gait 9 | 69
decreased circulating LDL chol... 9 | 38
decreased circulating serum al... 9 | 82
decreased hemoglobin content 9 | 68
decreased lean body mass 9 | 135
decreased startle reflex 9 | 75
increased bone mineral density 9 | 72
small superior vagus ganglion 9 | 74
abnormal kidney morphology 8 | 65
decreased circulating choleste... 8 | 93
decreased circulating glucose ... 8 | 126
decreased prepulse inhibition 8 | 82
enlarged epididymis 8 | 31
hypoactivity 8 | 132
increased monocyte cell number 8 | 63
decreased body length 7 | 101
decreased circulating HDL chol... 7 | 68
decreased circulating fructosa... 7 | 30
decreased erythrocyte cell num... 7 | 62
decreased mean corpuscular hem... 7 | 50
embryonic growth retardation 7 | 106
hydrometra 7 | 53
increased circulating triglyce... 7 | 42
increased fasted circulating g... 7 | 76
increased hemoglobin content 7 | 45
increased mean corpuscular vol... 7 | 92
abnormal coat-hair pigmentatio... 6 | 64
abnormal lens morphology 6 | 81
abnormal skin coloration 6 | 25
cataract 6 | 92
decreased circulating insulin ... 6 | 76
edema 6 | 59
enlarged spleen 6 | 41
hyperactivity 6 | 148
increased circulating choleste... 6 | 66
increased neutrophil cell numb... 6 | 46
limb grasping 6 | 41
prenatal lethality prior to he... 6 | 87
abnormal locomotor behavior 5 | 24
abnormal skin morphology 5 | 50
abnormal sleep behavior 5 | 70
abnormal testis morphology 5 | 43
decreased circulating alanine ... 5 | 47
decreased circulating aspartat... 5 | 34
decreased circulating bilirubi... 5 | 19
decreased eosinophil cell numb... 5 | 24
decreased fasted circulating g... 5 | 65
decreased mean corpuscular hem... 5 | 31
decreased threshold for audito... 5 | 26
increased circulating HDL chol... 5 | 80
increased heart weight 5 | 62
increased red blood cell distr... 5 | 34
increased startle reflex 5 | 112
male infertility 5 | 123
prolonged QT interval 5 | 38
prolonged ST segment 5 | 36
thrombocytopenia 5 | 56
abnormal retina morphology 4 | 71
decreased caudal vertebrae num... 4 | 53
decreased circulating alkaline... 4 | 46
decreased circulating free fat... 4 | 31
decreased circulating total pr... 4 | 49
decreased neutrophil cell numb... 4 | 42
increased circulating calcium ... 4 | 34
increased circulating free fat... 4 | 20
increased circulating fructosa... 4 | 13
increased circulating serum al... 4 | 22
pallor 4 | 34
thrombocytosis 4 | 27

Disease

Carcinoma 1,002 | 11,493
ovarian cancer 860 | 8,520
osteosarcoma 787 | 7,950
glioblastoma 610 | 5,792
medulloblastoma, large-cell 607 | 6,241
psoriasis 604 | 6,694
atypical teratoid / rhabdoid tumor 528 | 5,112
lung cancer 451 | 4,740
ependymoma 448 | 4,679
adult high grade glioma 376 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 371 | 3,291
group 3 medulloblastoma 351 | 4,104
malignant mesothelioma 348 | 3,232
Breast cancer 343 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 327 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 321 | 2,989
lung carcinoma 318 | 2,843
Astrocytoma, Pilocytic 315 | 3,081
invasive ductal carcinoma 302 | 2,951
primitive neuroectodermal tumor 293 | 3,035
non-small cell lung cancer 292 | 2,890
oligodendroglioma 274 | 2,850
pancreatic cancer 269 | 2,398
subependymal giant cell astrocytoma 262 | 2,287
lung adenocarcinoma 255 | 2,716
interstitial cystitis 253 | 2,312
astrocytic glioma 248 | 2,597
Kidney cancer 246 | 2,613
Cancer 222 | 2,499
tuberculosis 218 | 2,010
group 4 medulloblastoma 216 | 1,855
pituitary cancer 208 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 199 | 1,962
ulcerative colitis 192 | 1,819
Pick disease 185 | 1,894
cystic fibrosis 176 | 1,696
ductal carcinoma in situ 165 | 1,745
adrenocortical carcinoma 164 | 1,428
breast carcinoma 161 | 1,638
juvenile dermatomyositis 152 | 1,187
colon cancer 147 | 1,478
diabetes mellitus 147 | 1,728
Autosomal recessive predisposition 143 | 1,442
Schizophrenia 130 | 1,160
astrocytoma 127 | 1,146
spina bifida 122 | 1,074
Multiple myeloma 120 | 1,332
Rheumatoid arthritis 119 | 1,191
acute quadriplegic myopathy 118 | 1,158
primary pancreatic ductal adenocarcinoma 117 | 1,109
pediatric high grade glioma 115 | 1,064
dermatomyositis 108 | 966
active ulcerative colitis 99 | 764
cutaneous lupus erythematosus 98 | 1,057
Liver Cirrhosis, Experimental 96 | 769
gastric carcinoma 96 | 807
nasopharyngeal carcinoma 96 | 1,058
Atopic dermatitis 95 | 952
Alzheimer's disease 90 | 658
active Crohn's disease 90 | 922
Intellectual disability 89 | 1,016
Obesity 85 | 678
esophageal adenocarcinoma 83 | 737
Epilepsy 81 | 792
acute myeloid leukemia 79 | 783
primary Sjogren syndrome 78 | 735
non primary Sjogren syndrome sicca 77 | 891
aldosterone-producing adenoma 74 | 665
Duchenne muscular dystrophy 68 | 601
Waldenstrons macroglobulinemia 67 | 765
pancreatic carcinoma 67 | 562
fibroadenoma 66 | 559
medulloblastoma 66 | 720
Bipolar Disorder 64 | 666
progressive supranuclear palsy 64 | 676
autosomal dominant Emery-Dreifuss muscular dystrophy 63 | 510
mucosa-associated lymphoid tissue lymphoma 63 | 484
Seizures 62 | 596
Melanoma 61 | 711
hepatocellular carcinoma 59 | 547
Cognitive delay 58 | 608
Global developmental delay 58 | 608
Mental and motor retardation 58 | 608
Prostatic Neoplasms 58 | 495
Short stature 58 | 531
posterior fossa group A ependymoma 57 | 468
Muscle hypotonia 54 | 571
gastric cancer 53 | 459
Dull intelligence 52 | 645
Low intelligence 52 | 645
Mental Retardation 52 | 645
Mental deficiency 52 | 645
Poor school performance 52 | 645
Down syndrome 51 | 499
Hypertension 51 | 396
Atherosclerosis 50 | 291
Multiple Sclerosis 50 | 540
Neurodegenerative disease 50 | 414
Kidney disease 48 | 430
Breast Neoplasms 47 | 445

Tissue

Endocrine System 1,608 | 18,159
Female tissues 1,599 | 17,400
Digestive Tract 1,597 | 17,369
Skin and soft tissues 1,594 | 17,230
Male tissues 1,585 | 17,142
Liver and Pancreas 1,584 | 16,750
Urinary Tract 1,584 | 16,678
Blood and immune system 1,572 | 16,909
Nervous System 1,563 | 16,725
Respiratory system 1,552 | 16,393
Cardiovascular System 1,487 | 15,192

Target Family

Non-IDG 965 | 12,091
Enzyme 385 | 4,145
Transcription Factor 85 | 1,400
Kinase 68 | 634
Transporter 58 | 473
Ion Channel 22 | 344
GPCR 15 | 408
Epigenetic 10 | 242
TF/Epigenetic 3 | 38
Nuclear Receptor 2 | 48

Compartment GO Term

Vesicles 1,613 | 1,613
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Probable global transcription activator SNF2L1 SMARCA1 Tbio Non-IDG -2.20560 145.6 116
Transmembrane protein 184C TMEM184C Tbio Non-IDG -0.23045 1.81 39
Metastasis-associated protein MTA3 MTA3 Tbio Transcription Factor -1.36174 24.5 204
Importin-9 IPO9 Tbio Non-IDG -1.14983 12.2 108
Zinc transporter ZIP3 SLC39A3 Tbio Transporter -0.52290 3.15 87
Peroxisome biogenesis factor 2 PEX2 Tbio Non-IDG -1.76849 57.3 170
Protocadherin beta-14 PCDHB14 Tdark Non-IDG 0.78 0.14 90
Transportin-3 TNPO3 Tbio Non-IDG -1.74707 55.2 105
Zinc finger protein 638 ZNF638 Tbio Non-IDG -0.68946 6.04 67
NACHT, LRR and PYD domains-containing protein 2 NLRP2 Tbio Non-IDG -1.82146 68.5 245