Development Level

Tbio 965 | 10,625
Tdark 439 | 7,003
Tchem 178 | 1,890
Tclin 43 | 602

Collection

Kinase: IDG Consortium (Targets) 13 | 125
Ion Channel: IDG Consortium (Targets) 7 | 102
GPCR: IDG Consortium (Targets) 5 | 127
Kinase: IDG Consortium (Complete/Control) 3 | 37
GPCR: IDG Consortium (Complete/Control) 2 | 26

IMPC Phenotype

preweaning lethality, complete... 56 | 633
decreased total body fat amoun... 25 | 186
abnormal behavior 21 | 226
preweaning lethality, incomple... 20 | 260
decreased body weight 18 | 174
embryonic lethality prior to t... 16 | 187
decreased lean body mass 15 | 195
increased or absent threshold ... 15 | 128
enlarged heart 14 | 111
decreased circulating choleste... 13 | 85
increased mean corpuscular hem... 13 | 93
decreased bone mineral content 12 | 157
decreased grip strength 12 | 123
abnormal embryo size 11 | 112
decreased bone mineral density 11 | 126
decreased circulating HDL chol... 11 | 77
decreased circulating serum al... 11 | 79
increased bone mineral content 11 | 92
increased circulating alkaline... 11 | 119
decreased circulating triglyce... 10 | 83
hypoactivity 10 | 89
improved glucose tolerance 10 | 56
abnormal retina morphology 9 | 100
decreased body length 9 | 108
decreased eosinophil cell numb... 9 | 41
impaired glucose tolerance 9 | 52
increased fasted circulating g... 9 | 68
decreased circulating LDL chol... 8 | 37
decreased circulating glucose ... 8 | 121
decreased mean corpuscular vol... 8 | 50
decreased rib number 8 | 59
embryonic lethality prior to o... 8 | 148
hyperactivity 8 | 108
increased rib number 8 | 41
short tibia 8 | 82
abnormal bone structure 7 | 131
abnormal epididymis morphology 7 | 31
decreased hemoglobin content 7 | 53
decreased leukocyte cell numbe... 7 | 54
decreased lumbar vertebrae num... 7 | 62
decreased startle reflex 7 | 48
increased bone mineral density 7 | 52
increased circulating HDL chol... 7 | 63
increased exploration in new e... 7 | 56
increased hemoglobin content 7 | 45
increased mean corpuscular vol... 7 | 91
abnormal retinal pigmentation 6 | 61
abnormal seminal vesicle morph... 6 | 47
decreased circulating alanine ... 6 | 53
decreased circulating fructosa... 6 | 31
decreased circulating insulin ... 6 | 75
decreased prepulse inhibition 6 | 52
enlarged epididymis 6 | 27
increased circulating choleste... 6 | 53
increased grip strength 6 | 83
increased lean body mass 6 | 107
increased sacral vertebrae num... 6 | 62
abnormal coat-hair pigmentatio... 5 | 54
abnormal eye morphology 5 | 38
abnormal gait 5 | 51
abnormal heart morphology 5 | 51
abnormal rib morphology 5 | 28
abnormal sleep behavior 5 | 63
decreased CD4-positive, CD25-p... 5 | 24
decreased circulating aspartat... 5 | 27
decreased mean corpuscular hem... 5 | 34
decreased neutrophil cell numb... 5 | 37
increased circulating LDL chol... 5 | 15
increased circulating phosphat... 5 | 24
increased circulating potassiu... 5 | 31
increased circulating triglyce... 5 | 24
prenatal lethality prior to he... 5 | 64
abnormal QRS complex 4 | 25
abnormal coat appearance 4 | 25
abnormal lens morphology 4 | 73
abnormal neural tube closure 4 | 37
abnormal skin coloration 4 | 18
abnormal thoracic vertebrae mo... 4 | 16
abnormal tooth morphology 4 | 24
cardiovascular system phenotyp... 4 | 35
decreased blood urea nitrogen ... 4 | 31
decreased circulating alkaline... 4 | 41
decreased circulating bilirubi... 4 | 14
decreased circulating calcium ... 4 | 33
decreased circulating total pr... 4 | 41
decreased erythrocyte cell num... 4 | 43
decreased mean corpuscular hem... 4 | 19
female infertility 4 | 34
increased blood urea nitrogen ... 4 | 44
increased circulating aspartat... 4 | 17
increased circulating fructosa... 4 | 11
increased circulating serum al... 4 | 25
increased circulating sodium l... 4 | 71
increased total body fat amoun... 4 | 57
male infertility 4 | 62
prenatal lethality 4 | 16
decreased circulating free fat... 3 | 39
decreased fasted circulating g... 3 | 49
increased circulating calcium ... 3 | 32
increased prepulse inhibition 3 | 21

Disease

ovarian cancer 864 | 8,491
osteosarcoma 792 | 7,933
medulloblastoma, large-cell 613 | 6,234
psoriasis 611 | 6,685
glioblastoma 601 | 5,572
atypical teratoid / rhabdoid tumor 470 | 4,369
lung cancer 433 | 4,473
intraductal papillary-mucinous neoplasm (IPMN) 372 | 3,289
malignant mesothelioma 344 | 3,163
intraductal papillary-mucinous adenoma (IPMA) 328 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 321 | 2,988
lung carcinoma 319 | 2,844
pilocytic astrocytoma 319 | 3,086
invasive ductal carcinoma 303 | 2,950
Breast cancer 300 | 3,098
primitive neuroectodermal tumor 297 | 3,031
non-small cell lung cancer 283 | 2,798
oligodendroglioma 278 | 2,849
pediatric high grade glioma 267 | 2,712
subependymal giant cell astrocytoma 266 | 2,287
pancreatic cancer 263 | 2,300
lung adenocarcinoma 258 | 2,714
interstitial cystitis 255 | 2,299
ependymoma 248 | 2,514
ulcerative colitis 233 | 2,087
adult high grade glioma 231 | 2,148
astrocytic glioma 218 | 2,241
group 4 medulloblastoma 215 | 1,875
pituitary cancer 212 | 1,972
Cancer 210 | 2,346
Carcinoma 202 | 2,147
Pick disease 188 | 1,893
group 3 medulloblastoma 185 | 2,254
pancreatic ductal adenocarcinoma liver metastasis 177 | 1,795
cystic fibrosis 175 | 1,670
tuberculosis 171 | 1,563
ductal carcinoma in situ 166 | 1,745
adrenocortical carcinoma 164 | 1,427
astrocytoma 164 | 1,493
breast carcinoma 159 | 1,614
posterior fossa group A ependymoma 159 | 1,511
juvenile dermatomyositis 153 | 1,189
colon cancer 148 | 1,475
medulloblastoma 146 | 1,524
diabetes mellitus 142 | 1,663
primary pancreatic ductal adenocarcinoma 140 | 1,271
posterior fossa group B ependymoma 139 | 1,530
sonic hedgehog group medulloblastoma 135 | 1,482
spina bifida 122 | 1,064
Multiple myeloma 121 | 1,327
acute quadriplegic myopathy 119 | 1,157
Rheumatoid Arthritis 118 | 1,170
dermatomyositis 107 | 966
atypical teratoid/rhabdoid tumor 105 | 1,095
gastric carcinoma 102 | 832
cutaneous lupus erythematosus 98 | 1,056
nasopharyngeal carcinoma 98 | 1,056
Alzheimer's disease 96 | 644
Atopic dermatitis 94 | 944
active Crohn's disease 91 | 918
Obesity 84 | 616
esophageal adenocarcinoma 84 | 737
primary Sjogren syndrome 81 | 788
acute myeloid leukemia 79 | 785
aldosterone-producing adenoma 74 | 664
non primary Sjogren syndrome sicca 74 | 840
Duchenne muscular dystrophy 69 | 602
tuberculosis and treatment for 6 months 69 | 686
Waldenstrons macroglobulinemia 68 | 764
pancreatic carcinoma 68 | 567
fibroadenoma 66 | 557
progressive supranuclear palsy 65 | 674
mucosa-associated lymphoid tissue lymphoma 63 | 480
hepatocellular carcinoma 61 | 550
active ulcerative colitis 60 | 477
autosomal dominant Emery-Dreifuss muscular dystrophy 60 | 499
Prostatic Neoplasms 55 | 471
IGA Glomerulonephritis 53 | 454
Down syndrome 52 | 548
Intellectual disability 51 | 573
Schizophrenia 49 | 503
Atherosclerosis 48 | 275
gastric cancer 48 | 436
Neurodegenerative disease 47 | 383
Kidney disease 46 | 397
Mammary Neoplasms 46 | 410
chronic rhinosinusitis 46 | 512
Endometriosis 45 | 535
Multiple Sclerosis 45 | 498
Parkinson's disease 43 | 364
inflammatory breast cancer 43 | 404
Hypertension 42 | 293
interstitial lung disease 41 | 292
Amyotrophic Lateral Sclerosis 40 | 432
tuberculosis and treatment for 3 months 39 | 327
Coronary artery disease 38 | 240
Crohn's disease 38 | 304
Polycystic Ovary Syndrome 38 | 334
Asthma 36 | 349
urothelial carcinoma 36 | 318

Tissue

Female tissues 1,612 | 18,646
Digestive Tract 1,610 | 18,472
Endocrine System 1,609 | 18,511
Male tissues 1,605 | 17,968
Nervous System 1,605 | 18,560
Cardiovascular System 1,603 | 17,957
Liver and Pancreas 1,603 | 18,135
Blood and immune system 1,600 | 17,994
Urinary Tract 1,600 | 18,443
Respiratory system 1,596 | 17,483
Skin and soft tissues 1,592 | 18,114

Target Family

Non-IDG 978 | 11,969
Enzyme 384 | 4,146
Transcription Factor 85 | 1,400
Kinase 69 | 634
Transporter 58 | 473
Ion Channel 21 | 341
GPCR 15 | 408
Epigenetic 10 | 242
TF/Epigenetic 3 | 38
Nuclear Receptor 2 | 48

Compartment GO Term

Vesicles 1,625 | 1,625
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein 215 ZNF215 Tdark Transcription Factor -0.47111 3.15 74
Protein fosB FOSB Tbio Transcription Factor -2.64139 409.7 306
Muskelin MKLN1 Tbio Non-IDG -1.02215 14.1 90
Interferon gamma receptor 1 IFNGR1 Tchem Non-IDG -2.19638 160.9 450
Perilipin-4 PLIN4 Tbio Non-IDG -1.18472 13.1 53
Trafficking protein particle complex subunit 9 TRAPPC9 Tbio Non-IDG -2.14008 133.3 71
LIM domain-containing protein 2 LIMD2 Tdark Non-IDG -0.89117 2.22 53
E3 ubiquitin-protein ligase TRIM17 TRIM17 Tbio Enzyme -1.93165 73.2 100
Insulin-like growth factor-binding protein 3 IGFBP3 Tchem Non-IDG -3.34747 2121.3 411
TELO2-interacting protein 1 homolog TTI1 Tbio Non-IDG -0.83395 6.09 63