Development Level

Tbio 238 | 11,445
Tchem 69 | 1,598
Tdark 21 | 6,588
Tclin 19 | 613

IMPC Phenotype

preweaning lethality, complete... 15 | 979
preweaning lethality, incomple... 15 | 499
decreased vertical activity 6 | 208
enlarged heart 6 | 210
abnormal heart morphology 4 | 162
abnormal seminal vesicle morph... 4 | 114
cataract 4 | 92
edema 4 | 59
hypoactivity 4 | 132
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
abnormal retina morphology 3 | 71
decreased circulating choleste... 3 | 93
decreased circulating sodium l... 3 | 22
increased circulating alkaline... 3 | 122
increased or absent threshold ... 3 | 101
increased total body fat amoun... 3 | 134
male infertility 3 | 123
abnormal coat-hair pigmentatio... 2 | 64
abnormal eye morphology 2 | 68
abnormal humerus morphology 2 | 11
abnormal lens morphology 2 | 81
abnormal retinal vasculature m... 2 | 27
abnormal testis morphology 2 | 43
abnormal tooth morphology 2 | 24
decreased circulating insulin ... 2 | 76
decreased circulating serum al... 2 | 82
decreased circulating total pr... 2 | 49
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
decreased mean corpuscular hem... 2 | 31
decreased total body fat amoun... 2 | 207
enlarged lymph nodes 2 | 37
hyperactivity 2 | 148
increased circulating free fat... 2 | 20
increased circulating sodium l... 2 | 71
increased heart weight 2 | 62
increased leukocyte cell numbe... 2 | 47
premature death 2 | 5
short tibia 2 | 97
abnormal coat appearance 1 | 31
abnormal cornea morphology 1 | 31
abnormal femur morphology 1 | 14
abnormal heart left ventricle ... 1 | 16
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal retinal blood vessel ... 1 | 26
abnormal skin condition 1 | 6
abnormal snout morphology 1 | 23
abnormal tibia morphology 1 | 14
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating free fat... 1 | 31
decreased circulating fructosa... 1 | 30
decreased circulating phosphat... 1 | 27
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased fluid intake 1 | 3
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hemorrhage 1 | 23
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
increased aggression 1 | 4
increased blood urea nitrogen ... 1 | 48
increased body temperature 1 | 9
increased bone mineral content 1 | 108
increased cardiac muscle contr... 1 | 8
increased circulating LDL chol... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating triglyce... 1 | 42
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased thermal nociceptive ... 1 | 9
long tibia 1 | 25
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
small adrenal glands 1 | 16
small seminal vesicle 1 | 10
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

ovarian cancer 199 | 8,520
Carcinoma 191 | 11,493
osteosarcoma 179 | 7,950
psoriasis 157 | 6,694
lung cancer 144 | 4,740
Cancer 140 | 2,499
glioblastoma 127 | 5,792
medulloblastoma, large-cell 105 | 6,241
intraductal papillary-mucinous neoplasm (IPMN) 103 | 3,291
atypical teratoid / rhabdoid tumor 92 | 5,112
Breast cancer 91 | 3,578
ependymoma 89 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 89 | 2,955
lung adenocarcinoma 88 | 2,716
malignant mesothelioma 88 | 3,232
intraductal papillary-mucinous carcinoma (IPMC) 87 | 2,989
lung carcinoma 87 | 2,843
diabetes mellitus 83 | 1,728
pancreatic cancer 82 | 2,398
invasive ductal carcinoma 81 | 2,951
non-small cell lung cancer 81 | 2,890
tuberculosis 81 | 2,010
interstitial cystitis 75 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 75 | 1,962
Astrocytoma, Pilocytic 73 | 3,081
subependymal giant cell astrocytoma 70 | 2,287
adult high grade glioma 69 | 3,801
Autosomal recessive predisposition 66 | 1,442
group 3 medulloblastoma 65 | 4,104
ulcerative colitis 65 | 1,819
Multiple myeloma 57 | 1,332
Waldenstrons macroglobulinemia 55 | 765
cystic fibrosis 54 | 1,696
breast carcinoma 52 | 1,638
Liver Cirrhosis, Experimental 51 | 769
oligodendroglioma 51 | 2,850
acute quadriplegic myopathy 49 | 1,158
juvenile dermatomyositis 48 | 1,187
Kidney disease 47 | 430
Schizophrenia 45 | 1,160
pituitary cancer 45 | 1,972
astrocytic glioma 44 | 2,597
cutaneous lupus erythematosus 43 | 1,057
ductal carcinoma in situ 43 | 1,745
primary pancreatic ductal adenocarcinoma 43 | 1,109
primitive neuroectodermal tumor 43 | 3,035
Duchenne muscular dystrophy 41 | 601
Kidney cancer 41 | 2,613
astrocytoma 41 | 1,146
mucosa-associated lymphoid tissue lymphoma 41 | 484
Atopic dermatitis 40 | 952
esophageal adenocarcinoma 40 | 737
colon cancer 39 | 1,478
Pick disease 38 | 1,894
Rheumatoid arthritis 38 | 1,191
adrenocortical carcinoma 38 | 1,428
Vascular disease 37 | 319
Atherosclerosis 36 | 291
Alzheimer's disease 35 | 658
Arthritis 35 | 290
Hypertension 35 | 396
dermatomyositis 35 | 966
group 4 medulloblastoma 35 | 1,855
gastric carcinoma 34 | 807
Obesity 33 | 678
Liver disease 32 | 237
Hypertensive disease 31 | 292
Lung disease 31 | 142
Hepatomegaly 29 | 285
Seizures 29 | 596
Chemical and Drug Induced Liver Injury 28 | 195
Coronary artery disease 27 | 268
Intellectual disability 27 | 1,016
Prostatic Neoplasms 27 | 495
Splenomegaly 27 | 190
Cerebrovascular disease 26 | 238
autosomal dominant Emery-Dreifuss muscular dystrophy 26 | 510
nasopharyngeal carcinoma 26 | 1,058
Epilepsy 25 | 792
active ulcerative colitis 25 | 764
Asthma 24 | 385
Heart disease 24 | 306
active Crohn's disease 24 | 922
pancreatic carcinoma 24 | 562
Neoplasm Invasiveness 23 | 161
Osteoporosis 23 | 363
non primary Sjogren syndrome sicca 23 | 891
Dull intelligence 22 | 645
Low intelligence 22 | 645
Mental Retardation 22 | 645
Mental deficiency 22 | 645
Poor school performance 22 | 645
pediatric high grade glioma 22 | 1,064
primary Sjogren syndrome 22 | 735
Bipolar Disorder 21 | 666
Carcinoma, Hepatocellular 21 | 228
Liver carcinoma 21 | 240
Lung Neoplasms 21 | 232
fibroadenoma 21 | 559
gastric cancer 21 | 459

Tissue

Female tissues 336 | 17,400
Skin and soft tissues 335 | 17,230
Digestive Tract 334 | 17,369
Liver and Pancreas 334 | 16,750
Endocrine System 333 | 18,159
Blood and immune system 331 | 16,909
Urinary Tract 330 | 16,678
Respiratory system 325 | 16,393
Male tissues 324 | 17,142
Nervous System 318 | 16,725
Cardiovascular System 312 | 15,192

Target Family

Non-IDG 211 | 12,091
Enzyme 120 | 4,145
Kinase 14 | 634
Transcription Factor 2 | 1,400

Compartment GO Term

Vesicle lumen 347 | 347
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein unc-13 homolog D UNC13D Tbio Non-IDG -1.93790 85.1 158
Protein S100-A11 S100A11 Tbio Non-IDG -2.01412 110.0 311
Rho GTPase-activating protein 9 ARHGAP9 Tbio Enzyme -1.74771 54.3 35
Multiple myeloma tumor-associated protein 2 C1orf35 Tdark Non-IDG 0.00000 1.00 39
Neuroendocrine convertase 2 PCSK2 Tchem Enzyme -2.00248 109.8 132
Heme-binding protein 2 HEBP2 Tbio Non-IDG -1.05941 10.8 114
Torsin-4A TOR4A Tdark Non-IDG 0.77 0.09 17
Dipeptidyl peptidase 1 CTSC Tchem Enzyme -3.27566 1855.5 168
Grancalcin GCA Tbio Non-IDG -2.00540 93.2 76
Pentraxin-related protein PTX3 PTX3 Tbio Non-IDG -0.80888 8.68 307