Development Level

Tbio 868 | 10,625
Tchem 193 | 1,890
Tdark 143 | 7,003
Tclin 59 | 602

Collection

Kinase: IDG Consortium (Targets) 3 | 125
Ion Channel: IDG Consortium (Targets) 2 | 102
GPCR: IDG Consortium (Complete/Control) 1 | 26
GPCR: IDG Consortium (Targets) 1 | 127
Kinase: IDG Consortium (Complete/Control) 1 | 37

IMPC Phenotype

preweaning lethality, complete... 56 | 633
decreased total body fat amoun... 22 | 186
abnormal behavior 20 | 226
embryonic lethality prior to t... 20 | 187
preweaning lethality, incomple... 18 | 260
increased circulating alkaline... 17 | 119
embryonic lethality prior to o... 15 | 148
decreased grip strength 13 | 123
increased or absent threshold ... 13 | 128
decreased lean body mass 12 | 195
hypoactivity 12 | 89
decreased body length 11 | 108
decreased body weight 11 | 174
decreased bone mineral content 11 | 157
decreased bone mineral density 11 | 126
increased bone mineral content 11 | 92
increased bone mineral density 11 | 52
abnormal bone structure 10 | 131
decreased prepulse inhibition 10 | 52
increased lean body mass 10 | 107
increased mean corpuscular hem... 10 | 93
decreased circulating HDL chol... 9 | 77
decreased circulating glucose ... 9 | 121
decreased mean corpuscular vol... 9 | 50
increased sacral vertebrae num... 9 | 62
abnormal retina morphology 8 | 100
abnormal retinal pigmentation 8 | 61
decreased circulating serum al... 8 | 79
decreased circulating triglyce... 8 | 83
decreased lumbar vertebrae num... 8 | 62
decreased mean corpuscular hem... 8 | 34
decreased rib number 8 | 59
enlarged heart 8 | 111
increased circulating HDL chol... 8 | 63
increased fasted circulating g... 8 | 68
increased mean corpuscular vol... 8 | 91
thrombocytosis 8 | 23
abnormal lens morphology 7 | 73
abnormal sleep behavior 7 | 63
decreased circulating choleste... 7 | 85
decreased leukocyte cell numbe... 7 | 54
decreased monocyte cell number 7 | 28
increased blood urea nitrogen ... 7 | 44
increased circulating choleste... 7 | 53
short tibia 7 | 82
abnormal bone mineralization 6 | 55
cardiovascular system phenotyp... 6 | 35
decreased circulating LDL chol... 6 | 37
decreased hemoglobin content 6 | 53
improved glucose tolerance 6 | 56
increased circulating LDL chol... 6 | 15
increased circulating potassiu... 6 | 31
increased circulating sodium l... 6 | 71
increased grip strength 6 | 83
abnormal kidney morphology 5 | 30
abnormal seminal vesicle morph... 5 | 47
decreased NK T cell number 5 | 28
decreased circulating insulin ... 5 | 75
decreased eosinophil cell numb... 5 | 41
decreased erythrocyte cell num... 5 | 43
hyperactivity 5 | 108
impaired glucose tolerance 5 | 52
increased B cell number 5 | 23
increased circulating serum al... 5 | 25
limb grasping 5 | 35
small adrenal glands 5 | 15
abnormal coat-hair pigmentatio... 4 | 54
abnormal embryo size 4 | 112
abnormal epididymis morphology 4 | 31
abnormal heart morphology 4 | 51
abnormal rib morphology 4 | 28
decreased B cell number 4 | 30
decreased CD8-positive, alpha-... 4 | 26
decreased Ly6C low monocyte nu... 4 | 23
decreased caudal vertebrae num... 4 | 49
decreased circulating alkaline... 4 | 41
decreased circulating bilirubi... 4 | 14
decreased heart weight 4 | 44
decreased total retina thickne... 4 | 20
enlarged lymph nodes 4 | 27
increased NK cell number 4 | 19
increased T cell number 4 | 15
increased body weight 4 | 42
increased circulating calcium ... 4 | 32
increased circulating chloride... 4 | 43
increased leukocyte cell numbe... 4 | 37
abnormal behavioral response t... 3 | 52
abnormal coat appearance 3 | 25
abnormal gait 3 | 51
abnormal vibrissa morphology 3 | 17
decreased T cell number 3 | 31
decreased circulating calcium ... 3 | 33
decreased circulating iron lev... 3 | 25
decreased fasted circulating g... 3 | 49
decreased neutrophil cell numb... 3 | 37
enlarged spleen 3 | 26
increased hematocrit 3 | 36
increased hemoglobin content 3 | 45
prenatal lethality prior to he... 3 | 64
straub tail 3 | 26

Disease

ovarian cancer 691 | 8,491
osteosarcoma 584 | 7,933
psoriasis 506 | 6,685
medulloblastoma, large-cell 460 | 6,234
glioblastoma 444 | 5,572
lung cancer 354 | 4,473
Cancer 329 | 2,346
atypical teratoid / rhabdoid tumor 308 | 4,369
malignant mesothelioma 256 | 3,163
intraductal papillary-mucinous neoplasm (IPMN) 251 | 3,289
diabetes mellitus 249 | 1,663
invasive ductal carcinoma 248 | 2,950
pilocytic astrocytoma 247 | 3,086
intraductal papillary-mucinous adenoma (IPMA) 228 | 2,956
lung carcinoma 227 | 2,844
subependymal giant cell astrocytoma 214 | 2,287
intraductal papillary-mucinous carcinoma (IPMC) 211 | 2,988
pediatric high grade glioma 207 | 2,712
non-small cell lung cancer 204 | 2,798
Breast cancer 202 | 3,098
oligodendroglioma 200 | 2,849
lung adenocarcinoma 198 | 2,714
pancreatic cancer 194 | 2,300
ulcerative colitis 189 | 2,087
primitive neuroectodermal tumor 177 | 3,031
ependymoma 175 | 2,514
tuberculosis 170 | 1,563
Pick disease 165 | 1,893
Rheumatoid Arthritis 165 | 1,170
interstitial cystitis 165 | 2,299
adult high grade glioma 159 | 2,148
astrocytic glioma 152 | 2,241
Multiple myeloma 151 | 1,327
astrocytoma 150 | 1,493
Carcinoma 149 | 2,147
dermatomyositis 146 | 966
pancreatic ductal adenocarcinoma liver metastasis 141 | 1,795
group 4 medulloblastoma 138 | 1,875
cystic fibrosis 136 | 1,670
juvenile dermatomyositis 133 | 1,189
pituitary cancer 131 | 1,972
ductal carcinoma in situ 130 | 1,745
primary pancreatic ductal adenocarcinoma 123 | 1,271
breast carcinoma 121 | 1,614
posterior fossa group A ependymoma 114 | 1,511
Arthritis 109 | 248
cutaneous lupus erythematosus 109 | 1,056
medulloblastoma 108 | 1,524
Hypersensitivity reaction type II disease 103 | 235
colon cancer 103 | 1,475
Alzheimer's disease 101 | 644
sonic hedgehog group medulloblastoma 100 | 1,482
Kidney disease 99 | 397
acute quadriplegic myopathy 98 | 1,157
posterior fossa group B ependymoma 98 | 1,530
Neurodegenerative disease 96 | 383
group 3 medulloblastoma 96 | 2,254
adrenocortical carcinoma 93 | 1,427
Multiple Sclerosis 84 | 498
esophageal adenocarcinoma 84 | 737
primary Sjogren syndrome 83 | 788
spina bifida 83 | 1,064
Ankylosing spondylitis 80 | 138
gastric carcinoma 80 | 832
atypical teratoid/rhabdoid tumor 77 | 1,095
Waldenstrons macroglobulinemia 75 | 764
active Crohn's disease 71 | 918
Acquired immunodeficiency syndrome 70 | 164
Human immunodeficiency virus infectious disease 70 | 129
Down syndrome 69 | 548
Obesity 69 | 616
Duchenne muscular dystrophy 67 | 602
Juvenile rheumatoid arthritis 66 | 105
Uveitis 66 | 103
Liver disease 65 | 219
non primary Sjogren syndrome sicca 65 | 840
Anemia 62 | 252
acute myeloid leukemia 60 | 785
Hypertension 59 | 293
Atherosclerosis 58 | 275
Stevens-Johnson syndrome 58 | 91
Atopic dermatitis 57 | 944
Behcet's disease 57 | 74
Psoriatic arthritis 57 | 85
nasopharyngeal carcinoma 57 | 1,056
mucosa-associated lymphoid tissue lymphoma 56 | 480
Heart disease 54 | 279
tuberculosis and treatment for 6 months 54 | 686
Dermatitis 53 | 141
IGA Glomerulonephritis 53 | 454
progressive supranuclear palsy 53 | 674
Amyotrophic Lateral Sclerosis 52 | 432
Asthma 52 | 349
pancreatic carcinoma 52 | 567
aldosterone-producing adenoma 51 | 664
Coronary artery disease 50 | 240
Prostatic Neoplasms 50 | 471
Schizophrenia 50 | 503
Parkinson's disease 49 | 364
Intellectual disability 47 | 573

Tissue

Nervous System 1,182 | 18,560
Endocrine System 1,180 | 18,511
Female tissues 1,180 | 18,646
Urinary Tract 1,180 | 18,443
Liver and Pancreas 1,179 | 18,135
Digestive Tract 1,178 | 18,472
Male tissues 1,176 | 17,968
Cardiovascular System 1,172 | 17,957
Blood and immune system 1,171 | 17,994
Respiratory system 1,166 | 17,483
Skin and soft tissues 1,164 | 18,114

Target Family

Non-IDG 806 | 11,969
Enzyme 299 | 4,146
Kinase 59 | 634
Transporter 44 | 473
GPCR 28 | 408
Ion Channel 19 | 341
Transcription Factor 6 | 1,400
Epigenetic 1 | 242
oGPCR 1 | 421

Compartment GO Term

Vacuole 1,263 | 1,263
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuron-specific protein family member 1 NSG1 Tbio Non-IDG -1.10592 14.0 156
Huntingtin HTT Tchem Non-IDG -3.32908 2140.8 521
Sorting nexin-32 SNX32 Tdark Non-IDG 0.60 0.07 75
WD repeat-containing protein mio MIOS Tdark Non-IDG -1.44864 27.4 14
Interferon-induced transmembrane protein 3 IFITM3 Tbio Non-IDG -1.87958 126.0 172
Receptor tyrosine-protein kinase erbB-2 ERBB2 Tclin Kinase -4.25806 19000.3 3336
High affinity nerve growth factor receptor NTRK1 Tchem Kinase -3.03552 1003.4 1000
Alpha-soluble NSF attachment protein NAPA Tbio Non-IDG -1.91708 86.7 133
Rab15 effector protein REP15 Tbio Non-IDG -0.44863 2.71 15
N-acetylglucosamine-1-phosphotransferase subunit gamma GNPTG Tbio Enzyme -1.17901 15.7 80