Development Level

Tbio 577 | 10,625
Tchem 96 | 1,890
Tdark 85 | 7,003
Tclin 18 | 602

Collection

Eligible Ion Channel Proteins 1 | 117
Eligible Kinase Proteins 1 | 134
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 37 | 633
abnormal behavior 15 | 226
decreased total body fat amoun... 15 | 186
embryonic lethality prior to t... 12 | 187
hypoactivity 12 | 89
preweaning lethality, incomple... 12 | 260
embryonic lethality prior to o... 11 | 148
decreased mean corpuscular vol... 9 | 50
increased bone mineral content 9 | 92
increased bone mineral density 9 | 52
increased or absent threshold ... 9 | 128
decreased body length 8 | 108
decreased body weight 8 | 174
decreased grip strength 8 | 123
decreased prepulse inhibition 8 | 52
increased circulating alkaline... 8 | 119
increased lean body mass 8 | 107
increased mean corpuscular hem... 8 | 93
abnormal bone structure 7 | 131
abnormal retinal pigmentation 7 | 61
abnormal sleep behavior 7 | 63
decreased circulating serum al... 7 | 79
decreased mean corpuscular hem... 7 | 34
short tibia 7 | 82
abnormal retina morphology 6 | 100
cardiovascular system phenotyp... 6 | 35
decreased circulating HDL chol... 6 | 77
decreased circulating triglyce... 6 | 83
decreased lean body mass 6 | 195
enlarged heart 6 | 111
increased blood urea nitrogen ... 6 | 44
decreased bone mineral density 5 | 126
decreased circulating insulin ... 5 | 75
decreased hemoglobin content 5 | 53
decreased rib number 5 | 59
improved glucose tolerance 5 | 56
increased circulating potassiu... 5 | 31
increased circulating sodium l... 5 | 71
increased mean corpuscular vol... 5 | 91
increased sacral vertebrae num... 5 | 62
thrombocytosis 5 | 23
abnormal bone mineralization 4 | 55
abnormal epididymis morphology 4 | 31
abnormal kidney morphology 4 | 30
abnormal lens morphology 4 | 73
abnormal seminal vesicle morph... 4 | 47
decreased bone mineral content 4 | 157
decreased caudal vertebrae num... 4 | 49
decreased circulating choleste... 4 | 85
decreased circulating glucose ... 4 | 121
decreased erythrocyte cell num... 4 | 43
decreased leukocyte cell numbe... 4 | 54
decreased lumbar vertebrae num... 4 | 62
enlarged lymph nodes 4 | 27
hyperactivity 4 | 108
impaired glucose tolerance 4 | 52
increased circulating chloride... 4 | 43
increased circulating choleste... 4 | 53
increased circulating serum al... 4 | 25
increased fasted circulating g... 4 | 68
increased leukocyte cell numbe... 4 | 37
small adrenal glands 4 | 15
abnormal coat/hair pigmentatio... 3 | 54
abnormal heart morphology 3 | 51
abnormal skin morphology 3 | 23
abnormal testis morphology 3 | 30
absent pinna reflex 3 | 21
decreased circulating LDL chol... 3 | 37
decreased circulating phosphat... 3 | 15
decreased eosinophil cell numb... 3 | 41
decreased heart rate 3 | 10
decreased heart weight 3 | 44
decreased hematocrit 3 | 25
decreased mean corpuscular hem... 3 | 19
decreased total retina thickne... 3 | 20
enlarged epididymis 3 | 27
enlarged spleen 3 | 26
increased B cell number 3 | 23
increased body weight 3 | 42
increased circulating HDL chol... 3 | 63
increased circulating LDL chol... 3 | 15
increased rib number 3 | 41
limb grasping 3 | 35
prenatal lethality prior to he... 3 | 64
abnormal behavioral response t... 2 | 52
abnormal body wall morphology 2 | 7
abnormal lung morphology 2 | 15
abnormal retinal inner nuclear... 2 | 5
abnormal spleen morphology 2 | 36
abnormal vertebrae morphology 2 | 14
decreased T cell number 2 | 31
decreased circulating bilirubi... 2 | 14
decreased fasted circulating g... 2 | 49
increased NK T cell number 2 | 11
increased circulating calcium ... 2 | 32
increased erythrocyte cell num... 2 | 26
increased grip strength 2 | 83
increased prepulse inhibition 2 | 21
small testis 2 | 37
straub tail 2 | 26

Disease

ovarian cancer 430 | 8,484
osteosarcoma 332 | 7,933
psoriasis 299 | 6,685
medulloblastoma, large-cell 280 | 6,234
glioblastoma 269 | 5,572
Cancer 191 | 2,346
atypical teratoid / rhabdoid tumor 189 | 4,369
lung cancer 186 | 4,466
diabetes mellitus 150 | 1,663
intraductal papillary-mucinous neoplasm (IPMN) 144 | 3,289
invasive ductal carcinoma 143 | 2,950
pilocytic astrocytoma 142 | 3,086
lung carcinoma 132 | 2,844
intraductal papillary-mucinous adenoma (IPMA) 130 | 2,956
malignant mesothelioma 130 | 3,162
pediatric high grade glioma 127 | 2,712
subependymal giant cell astrocytoma 125 | 2,287
Breast cancer 124 | 3,094
intraductal papillary-mucinous carcinoma (IPMC) 117 | 2,988
oligodendroglioma 116 | 2,849
pancreatic cancer 114 | 2,300
non-small cell lung cancer 113 | 2,798
ependymoma 111 | 2,514
Rheumatoid Arthritis 109 | 1,160
Pick disease 101 | 1,893
lung adenocarcinoma 99 | 2,713
primitive neuroectodermal tumor 97 | 3,031
astrocytoma 96 | 1,493
ulcerative colitis 94 | 2,087
astrocytic glioma 93 | 2,241
tuberculosis 92 | 1,557
adult high grade glioma 91 | 2,148
Multiple myeloma 89 | 1,327
interstitial cystitis 89 | 2,299
Carcinoma 86 | 2,147
pancreatic ductal adenocarcinoma liver metastasis 85 | 1,795
juvenile dermatomyositis 84 | 1,189
primary pancreatic ductal adenocarcinoma 80 | 1,271
breast carcinoma 79 | 1,614
ductal carcinoma in situ 79 | 1,745
group 4 medulloblastoma 79 | 1,875
Hypersensitivity reaction type II disease 77 | 235
Ankylosing spondylitis 75 | 138
pituitary cancer 74 | 1,972
Arthritis 73 | 248
cystic fibrosis 73 | 1,665
dermatomyositis 72 | 933
medulloblastoma 64 | 1,524
acute quadriplegic myopathy 63 | 1,157
Juvenile rheumatoid arthritis 61 | 104
adrenocortical carcinoma 60 | 1,427
cutaneous lupus erythematosus 60 | 1,056
posterior fossa group A ependymoma 60 | 1,511
Acquired immunodeficiency syndrome 59 | 164
sonic hedgehog group medulloblastoma 59 | 1,482
Uveitis 58 | 103
colon cancer 58 | 1,475
group 3 medulloblastoma 58 | 2,254
Behcet's disease 56 | 74
Neurodegenerative disease 53 | 383
Psoriatic arthritis 52 | 83
esophageal adenocarcinoma 52 | 737
posterior fossa group B ependymoma 52 | 1,530
spina bifida 51 | 1,064
Multiple Sclerosis 50 | 498
Alzheimer's disease 49 | 644
primary Sjogren syndrome 49 | 789
Kidney disease 46 | 396
active Crohn's disease 44 | 918
Duchenne muscular dystrophy 43 | 602
Stevens-Johnson syndrome 43 | 78
Waldenstrons macroglobulinemia 43 | 765
atypical teratoid/rhabdoid tumor 41 | 1,095
gastric carcinoma 41 | 832
Anemia 40 | 252
non primary Sjogren syndrome sicca 39 | 840
Liver disease 38 | 219
Down syndrome 37 | 548
progressive supranuclear palsy 36 | 674
Congenital adrenal hyperplasia 35 | 74
Retinal vasculitis 35 | 36
Takayasu's arteritis 35 | 52
mucosa-associated lymphoid tissue lymphoma 35 | 480
acute myeloid leukemia 34 | 780
fibroadenoma 34 | 557
Atopic dermatitis 32 | 944
IGA Glomerulonephritis 30 | 454
aldosterone-producing adenoma 30 | 664
Hepatitis B 29 | 103
Leprosy 28 | 77
Hemochromatosis 26 | 55
Prostatic Neoplasms 26 | 471
tuberculosis and treatment for 6 months 26 | 686
Obesity 25 | 616
active ulcerative colitis 25 | 477
autosomal dominant Emery-Dreifuss muscular dystrophy 25 | 499
pancreatic carcinoma 25 | 567
Schizophrenia 24 | 501
hereditary spastic paraplegia 24 | 313
Intellectual disability 23 | 573

Tissue

Nervous System 701 | 18,561
Female tissues 700 | 18,647
Urinary Tract 700 | 18,444
Endocrine System 699 | 18,512
Digestive Tract 698 | 18,473
Liver and Pancreas 698 | 18,136
Male tissues 698 | 17,969
Cardiovascular System 696 | 17,958
Blood and immune system 692 | 17,995
Respiratory system 690 | 17,484
Skin and soft tissues 688 | 18,115

Target Family

Non-IDG 518 | 11,971
Enzyme 174 | 4,146
Transporter 39 | 473
Kinase 27 | 634
Ion Channel 12 | 341
GPCR 4 | 406
Transcription Factor 2 | 1,400

Compartment GO Term

Vacuolar part 776 | 776
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, A-3 alpha chain HLA-A Tbio Non-IDG -3.60614 4042.7 585
Lumican LUM Tbio Non-IDG -2.67820 509.4 209
Charged multivesicular body protein 2b CHMP2B Tbio Non-IDG -1.65708 53.0 166
Interleukin-1 receptor-associated kinase 1 IRAK1 Tchem Kinase -2.51851 320.4 729
HLA class I histocompatibility antigen, Cw-5 alpha chain HLA-C Tbio Non-IDG 777.4 0
Glypican-3 GPC3 Tbio Non-IDG -2.85848 794.8 523
ATP-binding cassette sub-family A member 2 ABCA2 Tbio Transporter -1.41708 32.2 125
Transmembrane 6 superfamily member 1 TM6SF1 Tdark Non-IDG -0.16400 2.15 54
HLA class I histocompatibility antigen, B-27 alpha chain HLA-B Tbio Non-IDG 1568.8 0
V-type proton ATPase catalytic subunit A ATP6V1A Tbio Enzyme -1.80191 64.7 120