Development Level

Tbio 74 | 10,625
Tchem 34 | 1,890
Tclin 6 | 602
Tdark 6 | 7,003

IMPC Phenotype

decreased total body fat amoun... 5 | 186
abnormal behavior 4 | 226
increased bone mineral content 4 | 92
increased lean body mass 4 | 107
preweaning lethality, incomple... 4 | 260
abnormal bone structure 3 | 131
decreased body length 3 | 108
decreased circulating insulin ... 3 | 75
decreased circulating serum al... 3 | 79
decreased circulating triglyce... 3 | 83
enlarged heart 3 | 111
enlarged lymph nodes 3 | 27
increased blood urea nitrogen ... 3 | 44
increased bone mineral density 3 | 52
increased or absent threshold ... 3 | 128
short tibia 3 | 82
abnormal heart morphology 2 | 51
abnormal lens morphology 2 | 73
abnormal seminal vesicle morph... 2 | 47
decreased bone mineral density 2 | 126
decreased caudal vertebrae num... 2 | 49
decreased circulating HDL chol... 2 | 77
decreased circulating glucose ... 2 | 121
decreased erythrocyte cell num... 2 | 43
decreased grip strength 2 | 123
decreased heart rate 2 | 10
decreased heart weight 2 | 44
decreased lean body mass 2 | 195
decreased leukocyte cell numbe... 2 | 54
decreased prepulse inhibition 2 | 52
hypoactivity 2 | 89
increased circulating alkaline... 2 | 119
premature death 2 | 5
preweaning lethality, complete... 2 | 633
small adrenal glands 2 | 15
abnormal behavioral response t... 1 | 52
abnormal coat-hair pigmentatio... 1 | 54
abnormal coping response 1 | 12
abnormal femur morphology 1 | 14
abnormal kidney morphology 1 | 30
abnormal retina morphology 1 | 100
abnormal retinal inner nuclear... 1 | 5
abnormal rib morphology 1 | 28
abnormal sensory capabilities-... 1 | 3
abnormal sleep behavior 1 | 63
abnormal snout morphology 1 | 18
abnormal spleen morphology 1 | 36
abnormal testis morphology 1 | 30
absent startle reflex 1 | 15
cardiovascular system phenotyp... 1 | 35
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased Ly6C low monocyte nu... 1 | 23
decreased T cell number 1 | 31
decreased alpha-beta T cell nu... 1 | 12
decreased basophil cell number 1 | 11
decreased bone mineral content 1 | 157
decreased circulating bilirubi... 1 | 14
decreased circulating choleste... 1 | 85
decreased circulating magnesiu... 1 | 11
decreased circulating phosphat... 1 | 15
decreased eosinophil cell numb... 1 | 41
decreased heart rate variabili... 1 | 11
decreased hemoglobin content 1 | 53
decreased mean corpuscular hem... 1 | 34
decreased monocyte cell number 1 | 28
decreased startle reflex 1 | 48
decreased total retina thickne... 1 | 20
decreased vertical activity 1 | 22
enlarged spleen 1 | 26
hyperactivity 1 | 108
impaired glucose tolerance 1 | 52
increased B cell number 1 | 23
increased Ly6C low monocyte nu... 1 | 8
increased cardiac muscle contr... 1 | 5
increased circulating alanine ... 1 | 11
increased circulating bilirubi... 1 | 16
increased circulating potassiu... 1 | 31
increased circulating triglyce... 1 | 24
increased erythrocyte cell num... 1 | 26
increased gamma-delta T cell n... 1 | 16
increased grip strength 1 | 83
increased heart weight 1 | 37
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular hem... 1 | 25
increased mean corpuscular vol... 1 | 91
increased prepulse inhibition 1 | 21
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
limb grasping 1 | 35
male infertility 1 | 62
mydriasis 1 | 9
polydactyly 1 | 22
small kidney 1 | 10
small seminal vesicle 1 | 6
small superior vagus ganglion 1 | 20
small testis 1 | 37
straub tail 1 | 26
thrombocytosis 1 | 23

Disease

ovarian cancer 73 | 8,491
glioblastoma 52 | 5,572
osteosarcoma 51 | 7,933
psoriasis 51 | 6,685
lung cancer 41 | 4,473
medulloblastoma, large-cell 39 | 6,234
malignant mesothelioma 35 | 3,163
Cancer 33 | 2,346
atypical teratoid / rhabdoid tumor 31 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 31 | 3,289
invasive ductal carcinoma 30 | 2,950
diabetes mellitus 29 | 1,663
pilocytic astrocytoma 29 | 3,086
subependymal giant cell astrocytoma 27 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 26 | 2,956
lung carcinoma 26 | 2,844
Breast cancer 23 | 3,098
astrocytoma 22 | 1,493
pancreatic cancer 22 | 2,300
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,988
non-small cell lung cancer 21 | 2,798
ductal carcinoma in situ 20 | 1,745
ulcerative colitis 20 | 2,087
Multiple myeloma 19 | 1,327
Neurodegenerative disease 19 | 383
juvenile dermatomyositis 19 | 1,189
lung adenocarcinoma 19 | 2,714
pediatric high grade glioma 19 | 2,712
pituitary cancer 19 | 1,972
adult high grade glioma 18 | 2,148
sonic hedgehog group medulloblastoma 18 | 1,482
breast carcinoma 17 | 1,614
cutaneous lupus erythematosus 17 | 1,056
cystic fibrosis 17 | 1,670
interstitial cystitis 17 | 2,299
oligodendroglioma 17 | 2,849
primary pancreatic ductal adenocarcinoma 17 | 1,271
Carcinoma 16 | 2,147
adrenocortical carcinoma 16 | 1,427
tuberculosis 16 | 1,563
Rheumatoid Arthritis 15 | 1,170
colon cancer 15 | 1,475
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,795
Duchenne muscular dystrophy 14 | 602
ependymoma 14 | 2,514
group 4 medulloblastoma 14 | 1,875
primitive neuroectodermal tumor 14 | 3,031
Mucopolysaccharidosis 13 | 24
Pick disease 13 | 1,893
acute quadriplegic myopathy 13 | 1,157
dermatomyositis 13 | 966
Vascular disease 12 | 281
esophageal adenocarcinoma 12 | 737
group 3 medulloblastoma 12 | 2,254
Atopic dermatitis 11 | 944
Prostatic Neoplasms 11 | 471
non primary Sjogren syndrome sicca 11 | 840
Alzheimer's disease 10 | 644
posterior fossa group A ependymoma 10 | 1,511
primary Sjogren syndrome 10 | 788
Down syndrome 9 | 548
Gangliosidosis 9 | 17
Kidney disease 9 | 397
gastric carcinoma 9 | 832
Anemia 8 | 252
Arthritis 8 | 248
Obesity 8 | 616
Polycystic Ovary Syndrome 8 | 334
Waldenstrons macroglobulinemia 8 | 764
astrocytic glioma 8 | 2,241
mucosa-associated lymphoid tissue lymphoma 8 | 480
posterior fossa group B ependymoma 8 | 1,530
spina bifida 8 | 1,064
Atherosclerosis 7 | 275
Gaucher's disease 7 | 25
Intellectual disability 7 | 573
Metachromatic leukodystrophy 7 | 13
Neuronal ceroid lipofuscinosis 7 | 28
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 499
fibroadenoma 7 | 557
hereditary spastic paraplegia 7 | 313
inclusion-cell disease 7 | 15
inflammatory breast cancer 7 | 404
limb girdle muscular dystrophy 2A 7 | 156
medulloblastoma 7 | 1,524
Chronic hepatitis C 6 | 12
Hypersensitivity reaction type II disease 6 | 235
Hypertension 6 | 293
IGA Glomerulonephritis 6 | 454
Krabbe disease 6 | 11
Multiple Sclerosis 6 | 498
Myopathy 6 | 128
active Crohn's disease 6 | 918
aldosterone-producing adenoma 6 | 664
Lung disease 5 | 136
Parkinson's disease 5 | 364
acute myeloid leukemia 5 | 785
nephrosclerosis 5 | 329
non-small cell lung carcinoma 5 | 413
urothelial carcinoma 5 | 318

Tissue

Cardiovascular System 118 | 17,957
Endocrine System 118 | 18,511
Female tissues 118 | 18,646
Liver and Pancreas 118 | 18,135
Nervous System 118 | 18,560
Urinary Tract 118 | 18,443
Blood and immune system 117 | 17,994
Male tissues 117 | 17,968
Skin and soft tissues 117 | 18,114
Digestive Tract 116 | 18,472
Respiratory system 114 | 17,483

Target Family

Non-IDG 59 | 11,969
Enzyme 56 | 4,146
Kinase 4 | 634
Transporter 1 | 473

Compartment GO Term

Vacuolar lumen 120 | 120
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E3 ubiquitin-protein ligase NEDD4-like NEDD4L Tbio Enzyme -2.50001 312.7 133
Hyaluronidase-1 HYAL1 Tbio Enzyme -1.85417 78.6 191
N-acetylglucosamine-6-sulfatase GNS Tbio Enzyme -2.64355 423.5 144
Perforin-1 PRF1 Tchem Non-IDG -3.16733 1480.8 325
Lysosomal thioesterase PPT2 PPT2 Tchem Enzyme -2.04384 109.5 95
Lysosomal amino acid transporter 1 homolog PQLC2 Tdark Non-IDG -0.24304 2.13 51
Probable cation-transporting ATPase 13A2 ATP13A2 Tbio Transporter -2.00056 92.5 127
Heat shock protein HSP 90-alpha HSP90AA1 Tchem Non-IDG -3.28941 4395.5 921
Syndecan-4 SDC4 Tbio Non-IDG -2.37601 255.6 244
Cathepsin B CTSB Tchem Enzyme -3.65774 4405.5 400