Development Level

Tbio 27 | 11,445
Tchem 20 | 1,598
Tclin 14 | 613

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal heart morphology 2 | 162
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
abnormal femur morphology 1 | 14
abnormal humerus morphology 1 | 11
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
decreased body temperature 1 | 2
decreased bone mineral content 1 | 151
decreased circulating aspartat... 1 | 34
decreased circulating chloride... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating potassiu... 1 | 20
decreased fasted circulating g... 1 | 65
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
enlarged uterus 1 | 11
hydrometra 1 | 53
increased bone mineral content 1 | 108
increased circulating potassiu... 1 | 29
increased fasted circulating g... 1 | 76
increased mean corpuscular hem... 1 | 96
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
limb grasping 1 | 41
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
small superior vagus ganglion 1 | 74

Disease

Cancer 57 | 2,499
lung cancer 41 | 4,740
malignant mesothelioma 40 | 3,232
ovarian cancer 38 | 8,520
Carcinoma 36 | 11,493
glioblastoma 36 | 5,792
invasive ductal carcinoma 34 | 2,951
osteosarcoma 34 | 7,950
cystic fibrosis 30 | 1,696
psoriasis 30 | 6,694
diabetes mellitus 29 | 1,728
interstitial cystitis 27 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,291
lung adenocarcinoma 27 | 2,716
Kidney disease 26 | 430
atypical teratoid / rhabdoid tumor 26 | 5,112
ependymoma 26 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 26 | 2,989
lung carcinoma 26 | 2,843
non-small cell lung cancer 26 | 2,890
Breast cancer 25 | 3,578
pancreatic cancer 25 | 2,398
Breast Neoplasms 24 | 445
Mammary Neoplasms 24 | 425
ductal carcinoma in situ 24 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,955
ulcerative colitis 24 | 1,819
Hypertension 22 | 396
Heart disease 21 | 306
Vascular disease 21 | 319
Astrocytoma, Pilocytic 20 | 3,081
adult high grade glioma 20 | 3,801
Liver Cirrhosis, Experimental 18 | 769
Neoplasm Metastasis 18 | 168
Prostatic Neoplasms 18 | 495
breast carcinoma 18 | 1,638
oligodendroglioma 18 | 2,850
Arthritis 17 | 290
Atherosclerosis 17 | 291
Diabetic retinopathy 17 | 56
Pulmonary Fibrosis 17 | 106
Schizophrenia 17 | 1,160
medulloblastoma, large-cell 17 | 6,241
pituitary cancer 17 | 1,972
tuberculosis 17 | 2,010
Lung disease 16 | 142
Neoplasm Invasiveness 16 | 161
adrenocortical carcinoma 16 | 1,428
primitive neuroectodermal tumor 16 | 3,035
Coronary artery disease 15 | 268
Depressive disorder 15 | 409
Liver disease 15 | 237
Cerebrovascular disease 14 | 238
Endometriosis 14 | 540
Eye disease 14 | 62
Inflammation 14 | 120
Reperfusion Injury 14 | 86
colon cancer 14 | 1,478
gastric carcinoma 14 | 807
primary pancreatic ductal adenocarcinoma 14 | 1,109
Alzheimer's disease 13 | 658
Anemia 13 | 365
Hypertensive disease 13 | 292
Obesity 13 | 678
astrocytic glioma 13 | 2,597
Asthma 12 | 385
Atopic dermatitis 12 | 952
Bipolar Disorder 12 | 666
Carcinoma, Hepatocellular 12 | 228
Carcinoma, Squamous Cell 12 | 110
Diabetes Mellitus, Experimental 12 | 108
Hypersensitivity reaction type II disease 12 | 253
Liver Cirrhosis 12 | 181
Liver carcinoma 12 | 240
Multiple Sclerosis 12 | 540
Myocardial Infarction 12 | 151
Pancreatic Neoplasms 12 | 85
Squamous cell carcinoma 12 | 129
group 3 medulloblastoma 12 | 4,104
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Adenocarcinoma 11 | 122
Hyperglycemia 11 | 137
Keratitis 11 | 62
Kidney cancer 11 | 2,613
Melanoma 11 | 711
Myocardial Ischemia 11 | 169
Pancreatic Neoplasm 11 | 85
Rheumatoid arthritis 11 | 1,191
Brain Ischemia 10 | 110
Calcinosis 10 | 70
Inflammatory bowel disease 10 | 151
Major Depressive Disorder 10 | 301
Mental Depression 10 | 333
Neoplastic Cell Transformation 10 | 89
Renal Cell Carcinoma 10 | 214
Skin cancer 10 | 469
Stomach Neoplasms 10 | 300
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 510
mucosa-associated lymphoid tissue lymphoma 10 | 484
subependymal giant cell astrocytoma 10 | 2,287

Tissue

Digestive Tract 61 | 17,369
Endocrine System 61 | 18,159
Female tissues 61 | 17,400
Liver and Pancreas 61 | 16,750
Male tissues 61 | 17,142
Nervous System 61 | 16,725
Skin and soft tissues 61 | 17,230
Blood and immune system 60 | 16,909
Respiratory system 60 | 16,393
Urinary Tract 60 | 16,678
Cardiovascular System 59 | 15,192

Target Family

Non-IDG 39 | 12,091
Kinase 9 | 634
Enzyme 8 | 4,145
Transcription Factor 4 | 1,400
GPCR 1 | 408

Compartment GO Term

VEGF-A complex 61 | 61
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Collagen alpha-1(XVIII) chain COL18A1 Tbio Non-IDG -3.18339 1561.4 433
Hematopoietic progenitor cell antigen CD34 CD34 Tbio Non-IDG -4.14691 13698.4 1952
Vascular endothelial growth factor receptor 1 FLT1 Tclin Kinase -3.38913 2189.4 953
C-C motif chemokine 2 CCL2 Tchem Non-IDG -3.84820 7088.3 1260
Stromal cell-derived factor 1 CXCL12 Tbio Non-IDG -3.48446 3085.9 607
Vascular endothelial growth factor receptor 3 FLT4 Tclin Kinase -2.72966 518.8 744
Prospero homeobox protein 1 PROX1 Tbio Transcription Factor -2.31691 210.1 472
Vascular endothelial growth factor C VEGFC Tbio Non-IDG -2.99495 1028.1 667
Placenta growth factor PGF Tclin Non-IDG -3.52194 3429.0 630