Development Level

Tbio 33 | 11,445
Tdark 2 | 6,588

IMPC Phenotype

abnormal behavior 3 | 298
preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
decreased bone mineral content 2 | 151
increased hematocrit 2 | 46
increased mean corpuscular vol... 2 | 92
increased total body fat amoun... 2 | 134
short tibia 2 | 97
abnormal coat appearance 1 | 31
abnormal coat- hair morphology 1 | 19
abnormal gait 1 | 69
abnormal hair texture 1 | 4
anophthalmia 1 | 33
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating triglyce... 1 | 79
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
hypoactivity 1 | 132
increased body length 1 | 32
increased circulating alkaline... 1 | 122
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased mean corpuscular hem... 1 | 36
increased startle reflex 1 | 112
limb grasping 1 | 41
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87

Disease

ovarian cancer 22 | 8,520
glioblastoma 13 | 5,792
lung cancer 13 | 4,740
osteosarcoma 13 | 7,950
medulloblastoma, large-cell 12 | 6,241
Carcinoma 11 | 11,493
Multiple myeloma 11 | 1,332
psoriasis 11 | 6,694
atypical teratoid / rhabdoid tumor 10 | 5,112
ependymoma 10 | 4,679
Cancer 8 | 2,499
adult high grade glioma 8 | 3,801
astrocytic glioma 8 | 2,597
Breast cancer 7 | 3,578
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
primitive neuroectodermal tumor 7 | 3,035
invasive ductal carcinoma 6 | 2,951
Intellectual disability 5 | 1,016
acute myeloid leukemia 5 | 783
acute quadriplegic myopathy 5 | 1,158
pancreatic cancer 5 | 2,398
astrocytoma 4 | 1,146
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
malignant mesothelioma 4 | 3,232
oligodendroglioma 4 | 2,850
pituitary cancer 4 | 1,972
Anemia 3 | 365
Autosomal recessive predisposition 3 | 1,442
Dull intelligence 3 | 645
Epilepsy 3 | 792
Liddle syndrome 3 | 14
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Pick disease 3 | 1,894
Poor school performance 3 | 645
Rheumatoid arthritis 3 | 1,191
Seizures 3 | 596
active Crohn's disease 3 | 922
diabetes mellitus 3 | 1,728
group 4 medulloblastoma 3 | 1,855
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
tuberculosis and treatment for 6 months 3 | 409
ulcerative colitis 3 | 1,819
Almond-shaped eyes 2 | 23
Alzheimer's disease 2 | 658
Angelman syndrome 2 | 34
Asthma 2 | 385
Astrocytoma, Pilocytic 2 | 3,081
Atopic dermatitis 2 | 952
Autosomal recessive limb-girdle muscular dystrophy type 2H 2 | 7
Big calvaria 2 | 147
Celiac disease 2 | 116
Cleft Palate 2 | 271
Cognitive delay 2 | 608
Concave bridge of nose 2 | 195
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Endometriosis 2 | 540
Familial encephalopathy with neuroserpin inclusion bodies 2 | 10
Global developmental delay 2 | 608
Hypoplastic mandible condyle 2 | 275
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Male infertility 2 | 206
Mandibular hypoplasia 2 | 275
Mental and motor retardation 2 | 608
Micrognathism 2 | 275
Myofibrillar myopathy 1 2 | 6
Myofibrillar myopathy 3 2 | 5
Nijmegen breakage syndrome 2 | 24
Parkinson's disease 2 | 392
Pick's disease 2 | 15
Short stature 2 | 531
Small head 2 | 374
Upward slant of palpebral fissure 2 | 75
Uranostaphyloschisis 2 | 167
Waldenstrons macroglobulinemia 2 | 765
adrenocortical carcinoma 2 | 1,428
breast carcinoma 2 | 1,638
cutaneous lupus erythematosus 2 | 1,057
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
interstitial cystitis 2 | 2,312
lung carcinoma 2 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
progressive supranuclear palsy 2 | 676
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
Abnormal urinary amino-acid findings 1 | 38
Acquired flat foot 1 | 72
Flatfoot 1 | 73
Gastrointestinal system disease 1 | 54
Poor speech 1 | 37
Underweight 1 | 17
Weight less than 3rd percentile 1 | 17

Tissue

Blood and immune system 35 | 16,909
Digestive Tract 35 | 17,369
Endocrine System 35 | 18,159
Female tissues 35 | 17,400
Male tissues 35 | 17,142
Urinary Tract 35 | 16,678
Cardiovascular System 34 | 15,192
Liver and Pancreas 34 | 16,750
Nervous System 34 | 16,725
Respiratory system 34 | 16,393
Skin and soft tissues 34 | 17,230

Target Family

Non-IDG 31 | 12,091
Enzyme 4 | 4,145

Compartment GO Term

Ubiquitin conjugating enzyme c... 35 | 35
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ubiquitin-conjugating enzyme E2 variant 1 UBE2V1 Tbio Non-IDG -1.33153 18.0 188
Peroxisomal targeting signal 1 receptor PEX5 Tbio Non-IDG -2.43126 272.8 138
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143
Transmembrane protein 189 TMEM189-UBE2V1 Tdark Non-IDG -2.27574 178.8 18
Ubiquitin-conjugating enzyme E2 A UBE2A Tbio Non-IDG -1.53597 32.3 117
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.12534 131.4 181
Ubiquitin-40S ribosomal protein S27a RPS27A Tbio Non-IDG -1.66231 61.9 139
Ubiquitin-conjugating enzyme E2 C UBE2C Tbio Non-IDG -1.93680 92.1 352
Ubiquitin-conjugating enzyme E2 L3 UBE2L3 Tbio Non-IDG -1.74801 58.4 325