Development Level

Tbio 8 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating fructosa... 1 | 30
decreased circulating total pr... 1 | 49
decreased lactate dehydrogenas... 1 | 16
decreased leukocyte cell numbe... 1 | 73
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 8 | 11,493
ovarian cancer 7 | 8,520
Pick disease 4 | 1,894
medulloblastoma, large-cell 4 | 6,241
osteosarcoma 4 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
psoriasis 4 | 6,694
Frontotemporal dementia 3 | 51
Inclusion body myopathy with Paget disease of bone and frontotemporal dementia 3 | 13
Cancer 2 | 2,499
Disease Progression 2 | 136
Dysphasia 2 | 23
Mammary Paget's disease 2 | 2
Multiple myeloma 2 | 1,332
astrocytoma 2 | 1,146
atypical teratoid / rhabdoid tumor 2 | 5,112
diabetes mellitus 2 | 1,728
glioblastoma 2 | 5,792
malignant mesothelioma 2 | 3,232
pituitary cancer 2 | 1,972
22q11 Deletion Syndrome 1 | 10
22q11 partial monosomy syndrome 1 | 9
22q11.2 deletion syndrome 1 | 8
Abnormal brain FDG positron emission tomography 1 | 9
Abnormality of aortic arch 1 | 9
Abnormality of the pharynx 1 | 19
Abnormality of the tonsils 1 | 10
Acne 1 | 52
Alexia 1 | 6
Alkaline phosphatase serum increased 1 | 29
Aphasia 1 | 26
Apraxias 1 | 27
Back Pain 1 | 7
Behavioral variant of frontotemporal dementia 1 | 8
CONOTRUNCAL ANOMALY FACE SYNDROME 1 | 9
Compulsive hoarding 1 | 7
Congenital hypoplasia of kidney 1 | 32
Convex nasal bridge 1 | 57
Corneal Neovascularization 1 | 13
Developmental arithmetic disorder 1 | 8
DiGeorge syndrome 1 | 47
Difficulty making arithmetical calculations 1 | 8
Dysgraphia 1 | 20
Dyslexia 1 | 43
Dysseborrheic dermatitis 1 | 13
EEG with continuous slow activity 1 | 7
Echolalia 1 | 12
Excess nuchal skin 1 | 30
Fasciculation, Tongue 1 | 8
Fatigable weakness of respiratory muscles 1 | 28
Fatigable weakness of swallowing muscles 1 | 28
Forgetful 1 | 40
Frontotemporal cerebral atrophy 1 | 8
Gait imbalance 1 | 17
Hammer Toe 1 | 23
Hypernasal voice 1 | 39
Hyperorality 1 | 7
Hypocalcemia 1 | 32
Hypoparathyroidism 1 | 41
Hypoplastic lobules 1 | 11
Impaired T cell function 1 | 14
Irritation - emotion 1 | 68
Lower limb hyperreflexia 1 | 10
Memory Loss 1 | 40
Memory impairment 1 | 40
Mild Mental Retardation 1 | 70
Muscle Cramp 1 | 55
Muscle weakness of limb 1 | 21
Myalgia 1 | 54
Nasal voice 1 | 39
Occipital myelomeningocele 1 | 8
Overfolded helix 1 | 24
Paget's disease of bone 1 | 36
Pain 1 | 103
Paralysed 1 | 42
Persistant truncus arteriosus 1 | 17
Platybasia 1 | 13
Poor speech 1 | 37
Problems speaking 1 | 37
Prominent nasal bridge 1 | 57
Reflex, Ankle, Absent 1 | 8
Repeated speech 1 | 9
Restlessness 1 | 14
Restrictive behavior 1 | 7
Restrictive behavior, interests, and activities 1 | 7
Rimmed vacuoles on biopsy 1 | 15
Rotting teeth 1 | 73
Scapular weakness 1 | 23
Seborrheic dermatitis 1 | 31
Shoulder girdle muscle atrophy 1 | 6
Shoulder girdle weakness 1 | 10
Shoulder weakness 1 | 10
Shprintzen syndrome 1 | 9
Small thymus 1 | 13
Social disinhibition 1 | 14
Stevens-Johnson syndrome 1 | 92
Tetany 1 | 18
Velocardiofacial syndrome 1 | 46
Winged scapula 1 | 23
Xerostomia 1 | 42

Tissue

Blood and immune system 10 | 16,909
Cardiovascular System 10 | 15,192
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678

Target Family

Enzyme 5 | 4,145
Non-IDG 5 | 12,091

Compartment GO Term

UFD1-NPL4 complex 10 | 10
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transitional endoplasmic reticulum ATPase VCP Tchem Enzyme -2.84978 736.4 416
Ubiquitin carboxyl-terminal hydrolase 5 USP5 Tchem Enzyme -2.22247 166.1 227
E3 ubiquitin-protein ligase AMFR AMFR Tbio Enzyme -2.46909 292.8 203
Ubiquitin recognition factor in ER-associated degradation protein 1 UFD1 Tbio Non-IDG -1.78158 54.5 187
UBX domain-containing protein 6 UBXN6 Tbio Non-IDG -0.94338 7.82 126
E3 ubiquitin-protein ligase RNF185 RNF185 Tbio Enzyme -0.43136 2.34 111
Nuclear protein localization protein 4 homolog NPLOC4 Tbio Non-IDG -1.55190 28.2 100
UBX domain-containing protein 1 UBXN1 Tbio Non-IDG -0.77492 6.54 100
E3 ubiquitin-protein ligase listerin LTN1 Tbio Enzyme -1.46975 30.1 88
UBX domain-containing protein 7 UBXN7 Tbio Non-IDG -1.23045 16.3 23