Development Level

Tbio 45 | 11,178
Tchem 17 | 1,885
Tclin 14 | 612
Tdark 1 | 6,569

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal bone structure 2 | 187
decreased grip strength 2 | 116
embryonic lethality prior to t... 2 | 278
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
abnormal skin coloration 1 | 25
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
cataract 1 | 92
convulsive seizures 1 | 13
decreased anxiety-related resp... 1 | 12
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased erythrocyte cell num... 1 | 39
increased grip strength 1 | 41
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased startle reflex 1 | 112
limb grasping 1 | 41
male infertility 1 | 123
pallor 1 | 34
polycystic kidney 1 | 15
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
urinary bladder obstruction 1 | 4

Disease

Carcinoma 49 | 11,192
ovarian cancer 45 | 8,297
glioblastoma 41 | 5,635
Cancer 36 | 2,388
atypical teratoid / rhabdoid tumor 36 | 4,971
ependymoma 36 | 4,559
medulloblastoma, large-cell 36 | 6,086
group 3 medulloblastoma 34 | 4,002
adult high grade glioma 31 | 3,701
lung cancer 30 | 4,607
osteosarcoma 30 | 7,766
Breast cancer 28 | 3,469
oligodendroglioma 28 | 2,768
Astrocytoma, Pilocytic 27 | 3,006
astrocytic glioma 27 | 2,530
psoriasis 27 | 6,514
primitive neuroectodermal tumor 23 | 2,957
Schizophrenia 22 | 1,136
malignant mesothelioma 22 | 3,135
non-small cell lung cancer 22 | 2,799
Toxic encephalopathy 21 | 139
Alzheimer's disease 20 | 640
diabetes mellitus 20 | 1,683
lung adenocarcinoma 20 | 2,627
subependymal giant cell astrocytoma 20 | 2,230
Pick disease 19 | 1,856
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,902
intraductal papillary-mucinous neoplasm (IPMN) 19 | 3,204
breast carcinoma 18 | 1,589
colon cancer 18 | 1,428
invasive ductal carcinoma 18 | 2,867
pancreatic cancer 18 | 2,322
Cerebrovascular disease 17 | 223
Epilepsy 17 | 775
Neurodegenerative disease 17 | 402
pituitary cancer 17 | 1,915
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,872
Intellectual disability 15 | 998
Amyotrophic lateral sclerosis 13 | 437
Parkinson's disease 13 | 378
nasopharyngeal carcinoma 13 | 1,024
Bipolar Disorder 12 | 646
Brain disease 12 | 95
Depressive disorder 12 | 401
Seizures 12 | 584
ulcerative colitis 12 | 1,765
Down syndrome 11 | 480
lung carcinoma 11 | 2,755
Autosomal recessive predisposition 10 | 1,407
Dementia 10 | 172
Nephroblastoma 10 | 50
Neuroblastoma 10 | 79
adrenocortical carcinoma 10 | 1,385
ductal carcinoma in situ 10 | 1,686
interstitial cystitis 10 | 2,237
Brain Ischemia 9 | 107
Dull intelligence 9 | 634
Heart disease 9 | 288
Kidney cancer 9 | 2,548
Liposarcoma 9 | 20
Lissencephaly 9 | 69
Low intelligence 9 | 634
Mental Depression 9 | 325
Mental Retardation 9 | 634
Mental deficiency 9 | 634
Multiple myeloma 9 | 1,296
Open-angle glaucoma 9 | 27
Poor school performance 9 | 634
Vascular disease 9 | 294
Acute lymphoid leukemia 8 | 25
Alcoholic Intoxication, Chronic 8 | 283
Burkitt's lymphoma 8 | 15
Carcinoma of breast 8 | 11
Diffuse non-Hodgkin's lymphoma, large cell 8 | 12
Duchenne muscular dystrophy 8 | 587
Eye disease 8 | 59
Follicular non-Hodgkin's lymphoma 8 | 17
Gestational trophoblastic neoplasia 8 | 14
HER2-positive carcinoma of breast 8 | 21
Hodgkin's disease 8 | 18
Hypertension 8 | 372
Kaposi's sarcoma 8 | 22
Langerhans cell histiocytosis, disseminated 8 | 10
Major Depressive Disorder 8 | 293
Malignant tumor of head and/or neck 8 | 15
Malignant tumor of ovary 8 | 25
Malignant tumor of testis 8 | 11
Metastatic Breast Carcinoma 8 | 21
Metastatic Prostate Carcinoma 8 | 18
Mood Disorders 8 | 181
Neuropathy 8 | 254
Ocular hypertension 8 | 40
Rhabdomyosarcoma 8 | 39
Secondary malignant neoplasm of pancreas 8 | 10
Small head 8 | 366
Unipolar Depression 8 | 244
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 492
cystic fibrosis 8 | 1,629
gastric carcinoma 8 | 781
transitional cell carcinoma 8 | 22

Tissue

Blood and immune system 74 | 16,909
Digestive Tract 74 | 17,369
Endocrine System 74 | 18,159
Female tissues 74 | 17,400
Male tissues 74 | 17,142
Nervous System 74 | 16,725
Skin and soft tissues 74 | 17,230
Liver and Pancreas 73 | 16,750
Urinary Tract 73 | 16,678
Respiratory system 69 | 16,393
Cardiovascular System 66 | 15,192

Target Family

Non-IDG 58 | 12,091
Enzyme 9 | 4,145
Transcription Factor 6 | 1,400
Epigenetic 3 | 242
Kinase 1 | 634

Compartment GO Term

Tubulin complex 77 | 77
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Vinculin VCL Tbio Non-IDG -3.34872 2107.1 637
Heat shock 70 kDa protein 4 HSPA4 Tbio Non-IDG -3.92672 8635.1 432
Tubulin beta-4B chain TUBB4B Tclin Non-IDG -0.95954 8.09 107
Cytoskeleton-associated protein 5 CKAP5 Tbio Non-IDG -2.12618 129.3 77
ES1 protein homolog, mitochondrial C21orf33 Tbio Non-IDG -2.41700 243.3 112
Tubulin-specific chaperone E TBCE Tbio Non-IDG -2.37521 233.9 118
T-complex protein 1 subunit alpha TCP1 Tbio Non-IDG -2.26984 173.7 468
Tubulin delta chain TUBD1 Tbio Non-IDG -1.28681 18.5 57
DNA-directed RNA polymerase II subunit RPB2 POLR2B Tbio Enzyme -2.49730 299.8 149
Vacuolar protein sorting-associated protein 72 homolog VPS72 Tbio Non-IDG -2.17465 143.5 142