Development Level

Tbio 315 | 10,625
Tdark 41 | 7,003
Tchem 34 | 1,890
Tclin 14 | 602

IMPC Term

preweaning lethality, complete... 14 | 633
abnormal behavior 10 | 226
decreased grip strength 8 | 123
decreased total body fat amoun... 7 | 186
embryonic lethality prior to t... 7 | 187
abnormal bone structure 6 | 131
decreased bone mineral content 6 | 157
decreased lean body mass 6 | 195
hypoactivity 6 | 89
decreased circulating HDL chol... 5 | 77
abnormal bone mineralization 4 | 55
decreased body length 4 | 108
decreased circulating choleste... 4 | 85
increased heart weight 4 | 37
preweaning lethality, incomple... 4 | 260
abnormal kidney morphology 3 | 30
abnormal sleep behavior 3 | 63
decreased body weight 3 | 174
decreased circulating LDL chol... 3 | 37
decreased vertical activity 3 | 22
embryonic lethality prior to o... 3 | 148
hyperactivity 3 | 108
increased circulating sodium l... 3 | 71
increased fasted circulating g... 3 | 68
increased mean corpuscular hem... 3 | 93
increased or absent threshold ... 3 | 128
increased total body fat amoun... 3 | 57
short tibia 3 | 82
abnormal QRS complex 2 | 25
abnormal coat/ hair morphology 2 | 18
abnormal embryo size 2 | 112
abnormal epididymis morphology 2 | 31
abnormal retinal pigmentation 2 | 61
abnormal testis morphology 2 | 30
decreased bone mineral density 2 | 126
decreased circulating free fat... 2 | 39
decreased circulating glucose ... 2 | 121
decreased circulating insulin ... 2 | 75
decreased fasted circulating g... 2 | 49
enlarged epididymis 2 | 27
immune system phenotype 2 | 17
increased erythrocyte cell num... 2 | 26
increased grip strength 2 | 83
increased hemoglobin content 2 | 45
persistence of hyaloid vascula... 2 | 22
thrombocytopenia 2 | 46
tremors 2 | 34
abnormal behavioral response t... 1 | 52
abnormal gait 1 | 51
abnormal heart morphology 1 | 51
abnormal motor capabilities/co... 1 | 4
abnormal neural tube closure 1 | 37
abnormal response to new envir... 1 | 8
abnormal retina morphology 1 | 100
abnormal retinal blood vessel ... 1 | 18
abnormal skin morphology 1 | 23
abnormal tail movements 1 | 12
abnormal vibrissa morphology 1 | 17
absent vibrissae 1 | 14
cardiovascular system phenotyp... 1 | 35
decreased caudal vertebrae num... 1 | 49
decreased circulating bilirubi... 1 | 14
decreased circulating chloride... 1 | 32
decreased circulating serum al... 1 | 79
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased exploration in new e... 1 | 9
decreased gamma-delta T cell n... 1 | 18
decreased hemoglobin content 1 | 53
decreased mean corpuscular hem... 1 | 19
decreased monocyte cell number 1 | 28
decreased neutrophil cell numb... 1 | 37
decreased total retina thickne... 1 | 20
enlarged heart atrium 1 | 2
hemorrhage 1 | 12
impaired glucose tolerance 1 | 52
increased B cell number 1 | 23
increased T cell number 1 | 15
increased blood urea nitrogen ... 1 | 44
increased body weight 1 | 42
increased circulating alkaline... 1 | 119
increased circulating aspartat... 1 | 17
increased circulating calcium ... 1 | 32
increased circulating chloride... 1 | 43
increased circulating potassiu... 1 | 31
increased circulating serum al... 1 | 25
increased hematocrit 1 | 36
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 25
increased mean corpuscular vol... 1 | 91
increased startle reflex 1 | 38
limb grasping 1 | 35
mydriasis 1 | 9
oligodactyly 1 | 14
prenatal lethality prior to he... 1 | 64
small spleen 1 | 11
small superior vagus ganglion 1 | 20
small testis 1 | 37
thrombocytosis 1 | 23

Disease

ovarian cancer 187 | 8,492
psoriasis 180 | 6,685
osteosarcoma 161 | 7,933
glioblastoma 160 | 5,572
medulloblastoma, large-cell 152 | 6,234
Cancer 120 | 2,346
atypical teratoid / rhabdoid tumor 119 | 4,369
pilocytic astrocytoma 117 | 3,086
diabetes mellitus 112 | 1,663
lung carcinoma 101 | 2,844
oligodendroglioma 97 | 2,849
lung cancer 90 | 4,473
pediatric high grade glioma 85 | 2,712
intraductal papillary-mucinous adenoma (IPMA) 77 | 2,956
primitive neuroectodermal tumor 77 | 3,031
Pick disease 76 | 1,893
astrocytoma 75 | 1,493
Rheumatoid Arthritis 72 | 1,171
intraductal papillary-mucinous neoplasm (IPMN) 72 | 3,289
Ankylosing spondylitis 71 | 138
subependymal giant cell astrocytoma 69 | 2,287
invasive ductal carcinoma 68 | 2,950
Hypersensitivity reaction type II disease 67 | 235
intraductal papillary-mucinous carcinoma (IPMC) 66 | 2,988
malignant mesothelioma 66 | 3,163
Arthritis 62 | 248
dermatomyositis 62 | 967
pancreatic cancer 62 | 2,300
Juvenile rheumatoid arthritis 61 | 105
Acquired immunodeficiency syndrome 60 | 164
interstitial cystitis 60 | 2,299
lung adenocarcinoma 60 | 2,714
ependymoma 59 | 2,514
Uveitis 57 | 103
Behcet's disease 56 | 74
Breast cancer 54 | 3,099
Psoriatic arthritis 52 | 85
astrocytic glioma 52 | 2,241
pituitary cancer 52 | 1,972
Multiple myeloma 51 | 1,328
Stevens-Johnson syndrome 51 | 91
non-small cell lung cancer 51 | 2,798
Human immunodeficiency virus infectious disease 49 | 129
adult high grade glioma 49 | 2,148
group 4 medulloblastoma 46 | 1,875
posterior fossa group A ependymoma 46 | 1,511
posterior fossa group B ependymoma 46 | 1,530
pancreatic ductal adenocarcinoma liver metastasis 43 | 1,795
medulloblastoma 42 | 1,524
breast carcinoma 39 | 1,614
ulcerative colitis 39 | 2,087
Dermatitis 38 | 141
group 3 medulloblastoma 38 | 2,254
Carcinoma 37 | 2,147
Alzheimer's disease 36 | 644
Multiple Sclerosis 36 | 498
Behcet's syndrome 35 | 50
Congenital adrenal hyperplasia 35 | 74
Kidney disease 35 | 397
Nephritis 35 | 63
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
Synovitis 35 | 72
Takayasu's arteritis 35 | 54
drug-induced hepatitis 35 | 44
Liver disease 32 | 219
ductal carcinoma in situ 32 | 1,745
tuberculosis 32 | 1,563
Anemia 31 | 252
colon cancer 31 | 1,475
Parkinson's disease 30 | 364
Schizophrenia 30 | 503
cystic fibrosis 30 | 1,670
sonic hedgehog group medulloblastoma 30 | 1,482
acute quadriplegic myopathy 29 | 1,157
juvenile dermatomyositis 29 | 1,189
atypical teratoid/rhabdoid tumor 27 | 1,095
pancreatic carcinoma 27 | 567
spina bifida 26 | 1,064
Hepatitis B 25 | 103
Leprosy 25 | 77
cutaneous lupus erythematosus 25 | 1,056
primary pancreatic ductal adenocarcinoma 25 | 1,271
Epilepsy 24 | 346
adrenocortical carcinoma 24 | 1,427
Hemochromatosis 23 | 55
Neurodegenerative disease 23 | 383
Obesity 23 | 616
Skin disease 23 | 65
active Crohn's disease 23 | 918
Waldenstrons macroglobulinemia 22 | 765
esophageal adenocarcinoma 22 | 737
Birdshot chorioretinopathy 21 | 23
Primary immunodeficiency disease 21 | 52
Duchenne muscular dystrophy 20 | 602
aldosterone-producing adenoma 18 | 664
gastric carcinoma 18 | 832
Bipolar Disorder 17 | 266
Intellectual disability 17 | 573
tuberculosis and treatment for 6 months 17 | 686

Tissue

Endocrine System 338 | 18,512
Female tissues 338 | 18,647
Nervous System 338 | 18,561
Digestive Tract 337 | 18,473
Cardiovascular System 336 | 17,958
Liver and Pancreas 336 | 18,136
Blood and immune system 335 | 17,995
Urinary Tract 335 | 18,444
Male tissues 334 | 17,969
Respiratory system 330 | 17,484
Skin and soft tissues 327 | 18,115

Target Family

Non-IDG 324 | 11,969
Enzyme 50 | 4,146
Transporter 14 | 473
Ion Channel 5 | 341
Kinase 5 | 634
Transcription Factor 3 | 1,400
GPCR 2 | 408
Epigenetic 1 | 242

Compartment GO Term

Transport vesicle 404 | 404
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, alpha chain G HLA-G Tbio Non-IDG -3.07995 1275.9 729
Syncollin SYCN Tdark Non-IDG -2.12341 132.9 35
Synapsin-1 SYN1 Tbio Non-IDG -2.85684 687.9 716
Protein unc-13 homolog D UNC13D Tbio Non-IDG -1.89144 80.2 134
Cell cycle control protein 50A TMEM30A Tbio Non-IDG -1.01830 9.66 25
Transmembrane emp24 domain-containing protein 3 TMED3 Tbio Non-IDG -0.85200 7.21 86
Defensin-5 DEFA5 Tbio Non-IDG -1.89753 82.9 161
Protein YIF1B YIF1B Tbio Non-IDG -0.80844 5.59 61
Gamma-secretase subunit APH-1B APH1B Tchem Enzyme -1.15543 13.7 52
HLA class II histocompatibility antigen, DP beta 1 chain HLA-DPB1 Tbio Non-IDG -2.67719 572.7 274