Development Level

Tbio 315 | 10,625
Tdark 41 | 7,003
Tchem 34 | 1,890
Tclin 14 | 602

Collection

Kinase: IDG Consortium (Complete/Control) 1 | 37

IMPC Phenotype

preweaning lethality, complete... 14 | 633
abnormal behavior 10 | 226
decreased grip strength 8 | 123
decreased total body fat amoun... 7 | 186
embryonic lethality prior to t... 7 | 187
abnormal bone structure 6 | 131
decreased bone mineral content 6 | 157
decreased lean body mass 6 | 195
hypoactivity 6 | 89
decreased circulating HDL chol... 5 | 77
abnormal bone mineralization 4 | 55
decreased body length 4 | 108
decreased circulating choleste... 4 | 85
increased heart weight 4 | 37
preweaning lethality, incomple... 4 | 260
abnormal kidney morphology 3 | 30
abnormal sleep behavior 3 | 63
decreased body weight 3 | 174
decreased circulating LDL chol... 3 | 37
decreased vertical activity 3 | 22
embryonic lethality prior to o... 3 | 148
hyperactivity 3 | 108
increased circulating sodium l... 3 | 71
increased fasted circulating g... 3 | 68
increased mean corpuscular hem... 3 | 93
increased or absent threshold ... 3 | 128
increased total body fat amoun... 3 | 57
short tibia 3 | 82
abnormal QRS complex 2 | 25
abnormal coat- hair morphology 2 | 18
abnormal embryo size 2 | 112
abnormal epididymis morphology 2 | 31
abnormal retinal pigmentation 2 | 61
abnormal testis morphology 2 | 30
decreased bone mineral density 2 | 126
decreased circulating free fat... 2 | 39
decreased circulating glucose ... 2 | 121
decreased circulating insulin ... 2 | 75
decreased fasted circulating g... 2 | 49
enlarged epididymis 2 | 27
immune system phenotype 2 | 17
increased erythrocyte cell num... 2 | 26
increased grip strength 2 | 83
increased hemoglobin content 2 | 45
persistence of hyaloid vascula... 2 | 22
thrombocytopenia 2 | 46
tremors 2 | 34
abnormal behavioral response t... 1 | 52
abnormal gait 1 | 51
abnormal heart morphology 1 | 51
abnormal motor capabilities-co... 1 | 4
abnormal neural tube closure 1 | 37
abnormal response to new envir... 1 | 8
abnormal retina morphology 1 | 100
abnormal retinal blood vessel ... 1 | 18
abnormal skin morphology 1 | 23
abnormal tail movements 1 | 12
abnormal vibrissa morphology 1 | 17
absent vibrissae 1 | 14
cardiovascular system phenotyp... 1 | 35
decreased caudal vertebrae num... 1 | 49
decreased circulating bilirubi... 1 | 14
decreased circulating chloride... 1 | 32
decreased circulating serum al... 1 | 79
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased exploration in new e... 1 | 9
decreased gamma-delta T cell n... 1 | 18
decreased hemoglobin content 1 | 53
decreased mean corpuscular hem... 1 | 19
decreased monocyte cell number 1 | 28
decreased neutrophil cell numb... 1 | 37
decreased total retina thickne... 1 | 20
enlarged heart atrium 1 | 2
hemorrhage 1 | 12
impaired glucose tolerance 1 | 52
increased B cell number 1 | 23
increased T cell number 1 | 15
increased blood urea nitrogen ... 1 | 44
increased body weight 1 | 42
increased circulating alkaline... 1 | 119
increased circulating aspartat... 1 | 17
increased circulating calcium ... 1 | 32
increased circulating chloride... 1 | 43
increased circulating potassiu... 1 | 31
increased circulating serum al... 1 | 25
increased hematocrit 1 | 36
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 25
increased mean corpuscular vol... 1 | 91
increased startle reflex 1 | 38
limb grasping 1 | 35
mydriasis 1 | 9
oligodactyly 1 | 14
prenatal lethality prior to he... 1 | 64
small spleen 1 | 11
small superior vagus ganglion 1 | 20
small testis 1 | 37
thrombocytosis 1 | 23

Disease

ovarian cancer 187 | 8,491
psoriasis 180 | 6,685
osteosarcoma 161 | 7,933
glioblastoma 160 | 5,572
medulloblastoma, large-cell 152 | 6,234
Cancer 120 | 2,346
atypical teratoid / rhabdoid tumor 119 | 4,369
pilocytic astrocytoma 117 | 3,086
diabetes mellitus 112 | 1,663
lung carcinoma 101 | 2,844
oligodendroglioma 97 | 2,849
lung cancer 90 | 4,473
pediatric high grade glioma 85 | 2,712
intraductal papillary-mucinous adenoma (IPMA) 77 | 2,956
primitive neuroectodermal tumor 77 | 3,031
Pick disease 76 | 1,893
astrocytoma 75 | 1,493
Rheumatoid Arthritis 72 | 1,170
intraductal papillary-mucinous neoplasm (IPMN) 72 | 3,289
Ankylosing spondylitis 71 | 138
subependymal giant cell astrocytoma 69 | 2,287
invasive ductal carcinoma 68 | 2,950
Hypersensitivity reaction type II disease 67 | 235
intraductal papillary-mucinous carcinoma (IPMC) 66 | 2,988
malignant mesothelioma 66 | 3,163
Arthritis 62 | 248
dermatomyositis 62 | 966
pancreatic cancer 62 | 2,300
Juvenile rheumatoid arthritis 61 | 105
Acquired immunodeficiency syndrome 60 | 164
interstitial cystitis 60 | 2,299
lung adenocarcinoma 60 | 2,714
ependymoma 59 | 2,514
Uveitis 57 | 103
Behcet's disease 56 | 74
Breast cancer 54 | 3,098
Psoriatic arthritis 52 | 85
astrocytic glioma 52 | 2,241
pituitary cancer 52 | 1,972
Multiple myeloma 51 | 1,327
Stevens-Johnson syndrome 51 | 91
non-small cell lung cancer 51 | 2,798
Human immunodeficiency virus infectious disease 49 | 129
adult high grade glioma 49 | 2,148
group 4 medulloblastoma 46 | 1,875
posterior fossa group A ependymoma 46 | 1,511
posterior fossa group B ependymoma 46 | 1,530
pancreatic ductal adenocarcinoma liver metastasis 43 | 1,795
medulloblastoma 42 | 1,524
breast carcinoma 39 | 1,614
ulcerative colitis 39 | 2,087
Dermatitis 38 | 141
group 3 medulloblastoma 38 | 2,254
Carcinoma 37 | 2,147
Alzheimer's disease 36 | 644
Multiple Sclerosis 36 | 498
Behcet's syndrome 35 | 50
Congenital adrenal hyperplasia 35 | 74
Kidney disease 35 | 397
Nephritis 35 | 63
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
Synovitis 35 | 72
Takayasu's arteritis 35 | 54
drug-induced hepatitis 35 | 44
Liver disease 32 | 219
ductal carcinoma in situ 32 | 1,745
tuberculosis 32 | 1,563
Anemia 31 | 252
colon cancer 31 | 1,475
Parkinson's disease 30 | 364
Schizophrenia 30 | 503
cystic fibrosis 30 | 1,670
sonic hedgehog group medulloblastoma 30 | 1,482
acute quadriplegic myopathy 29 | 1,157
juvenile dermatomyositis 29 | 1,189
atypical teratoid/rhabdoid tumor 27 | 1,095
pancreatic carcinoma 27 | 567
spina bifida 26 | 1,064
Hepatitis B 25 | 103
Leprosy 25 | 77
cutaneous lupus erythematosus 25 | 1,056
primary pancreatic ductal adenocarcinoma 25 | 1,271
Epilepsy 24 | 346
adrenocortical carcinoma 24 | 1,427
Hemochromatosis 23 | 55
Neurodegenerative disease 23 | 383
Obesity 23 | 616
Skin disease 23 | 65
active Crohn's disease 23 | 918
Waldenstrons macroglobulinemia 22 | 764
esophageal adenocarcinoma 22 | 737
Birdshot chorioretinopathy 21 | 23
Primary immunodeficiency disease 21 | 52
Duchenne muscular dystrophy 20 | 602
aldosterone-producing adenoma 18 | 664
gastric carcinoma 18 | 832
Bipolar Disorder 17 | 266
Intellectual disability 17 | 573
tuberculosis and treatment for 6 months 17 | 686

Tissue

Endocrine System 338 | 18,511
Female tissues 338 | 18,646
Nervous System 338 | 18,560
Digestive Tract 337 | 18,472
Cardiovascular System 336 | 17,957
Liver and Pancreas 336 | 18,135
Blood and immune system 335 | 17,994
Urinary Tract 335 | 18,443
Male tissues 334 | 17,968
Respiratory system 330 | 17,483
Skin and soft tissues 327 | 18,114

Target Family

Non-IDG 324 | 11,969
Enzyme 50 | 4,146
Transporter 14 | 473
Ion Channel 5 | 341
Kinase 5 | 634
Transcription Factor 3 | 1,400
GPCR 2 | 408
Epigenetic 1 | 242

Compartment GO Term

Transport vesicle 404 | 404
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alpha-soluble NSF attachment protein NAPA Tbio Non-IDG -1.91708 86.7 133
Protein YIPF1 YIPF1 Tbio Non-IDG -2.07470 81.5 69
Folate receptor alpha FOLR1 Tchem Non-IDG -2.27944 181.4 235
Dipeptidyl peptidase 1 CTSC Tchem Enzyme -3.24582 1740.5 143
Spexin SPX Tbio Non-IDG -2.76281 568.1 18
Oviduct-specific glycoprotein OVGP1 Tbio Enzyme -2.24980 179.2 53
HLA class I histocompatibility antigen, B-35 alpha chain HLA-B Tbio Non-IDG -1.87358 1568.8 0
Alpha-1-antitrypsin SERPINA1 Tbio Non-IDG -3.73976 5495.0 809
Maltase-glucoamylase, intestinal MGAM Tclin Enzyme -4.50018 27956.4 30
Protransforming growth factor alpha TGFA Tbio Non-IDG -2.13802 123.3 575