Development Level

Tbio 349 | 11,651
Tdark 43 | 6,593
Tchem 27 | 1,388
Tclin 16 | 612

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 23 | 979
preweaning lethality, incomple... 13 | 499
embryonic lethality prior to t... 10 | 278
abnormal behavior 8 | 298
abnormal bone structure 8 | 187
decreased bone mineral content 8 | 151
abnormal sleep behavior 7 | 70
decreased total body fat amoun... 7 | 207
decreased grip strength 6 | 116
abnormal embryo size 5 | 220
abnormal kidney morphology 5 | 65
abnormal seminal vesicle morph... 5 | 114
embryonic lethality prior to o... 5 | 239
hypoactivity 5 | 132
decreased body length 4 | 101
decreased bone mineral density 4 | 126
decreased circulating choleste... 4 | 93
decreased vertical activity 4 | 208
embryonic growth retardation 4 | 106
increased circulating sodium l... 4 | 71
increased heart weight 4 | 62
increased startle reflex 4 | 112
short tibia 4 | 97
small testis 4 | 58
abnormal behavioral response t... 3 | 66
abnormal retina morphology 3 | 71
abnormal testis morphology 3 | 43
decreased circulating HDL chol... 3 | 68
decreased circulating LDL chol... 3 | 38
decreased circulating glucose ... 3 | 126
hyperactivity 3 | 148
increased fasted circulating g... 3 | 76
increased mean corpuscular hem... 3 | 96
increased total body fat amoun... 3 | 134
abnormal cecum morphology 2 | 7
abnormal coat- hair morphology 2 | 19
abnormal eye morphology 2 | 68
abnormal heart morphology 2 | 162
abnormal locomotor behavior 2 | 24
brachydactyly 2 | 19
convulsive seizures 2 | 13
decreased body weight 2 | 161
decreased circulating free fat... 2 | 31
decreased circulating insulin ... 2 | 76
decreased circulating serum al... 2 | 82
decreased circulating triglyce... 2 | 79
decreased fasted circulating g... 2 | 65
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular hem... 2 | 50
decreased mean corpuscular hem... 2 | 31
enlarged cecum 2 | 5
impaired glucose tolerance 2 | 75
increased blood urea nitrogen ... 2 | 48
increased body length 2 | 32
increased bone mineral content 2 | 108
increased erythrocyte cell num... 2 | 39
increased grip strength 2 | 41
increased heart rate 2 | 23
increased hematocrit 2 | 46
increased hemoglobin content 2 | 45
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 36
increased mean corpuscular vol... 2 | 92
increased monocyte cell number 2 | 63
increased or absent threshold ... 2 | 101
limb grasping 2 | 41
persistence of hyaloid vascula... 2 | 33
prenatal lethality 2 | 28
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
small epididymis 2 | 3
small spleen 2 | 19
small superior vagus ganglion 2 | 74
tremors 2 | 39
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal motor capabilities-co... 1 | 5
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal spleen morphology 1 | 55
abnormal tail movements 1 | 12
decreased caudal vertebrae num... 1 | 53
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased food intake 1 | 13
decreased neutrophil cell numb... 1 | 42
decreased total retina thickne... 1 | 17
enlarged urinary bladder 1 | 8
hydrometra 1 | 53
impaired pupillary reflex 1 | 26
increased body weight 1 | 25
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating triglyce... 1 | 42
thrombocytosis 1 | 27

Disease

Carcinoma 248 | 11,493
ovarian cancer 203 | 8,520
psoriasis 189 | 6,694
glioblastoma 181 | 5,792
osteosarcoma 173 | 7,950
medulloblastoma, large-cell 165 | 6,241
atypical teratoid / rhabdoid tumor 148 | 5,112
ependymoma 145 | 4,679
Astrocytoma, Pilocytic 129 | 3,081
Cancer 125 | 2,499
adult high grade glioma 123 | 3,801
diabetes mellitus 117 | 1,728
lung carcinoma 105 | 2,843
oligodendroglioma 104 | 2,850
lung cancer 103 | 4,740
astrocytic glioma 96 | 2,597
group 3 medulloblastoma 95 | 4,104
primitive neuroectodermal tumor 85 | 3,035
Pick disease 84 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 79 | 2,955
Rheumatoid arthritis 75 | 1,191
invasive ductal carcinoma 75 | 2,951
intraductal papillary-mucinous neoplasm (IPMN) 73 | 3,291
subependymal giant cell astrocytoma 73 | 2,287
malignant mesothelioma 72 | 3,232
Ankylosing spondylitis 71 | 140
Breast cancer 71 | 3,578
Behcet's disease 70 | 89
tuberculosis 70 | 2,010
intraductal papillary-mucinous carcinoma (IPMC) 68 | 2,989
pancreatic cancer 68 | 2,398
Hypersensitivity reaction type II disease 67 | 253
lung adenocarcinoma 64 | 2,716
Arthritis 63 | 290
Juvenile rheumatoid arthritis 62 | 111
interstitial cystitis 62 | 2,312
dermatomyositis 61 | 966
Acquired immunodeficiency syndrome 60 | 197
non-small cell lung cancer 60 | 2,890
Schizophrenia 57 | 1,160
Uveitis 57 | 103
Herpes zoster 56 | 68
Kidney cancer 56 | 2,613
pituitary cancer 55 | 1,972
Multiple myeloma 53 | 1,332
Psoriatic arthritis 52 | 86
Stevens-Johnson syndrome 51 | 92
group 4 medulloblastoma 50 | 1,855
Human immunodeficiency virus infectious disease 49 | 138
pancreatic ductal adenocarcinoma liver metastasis 47 | 1,962
Alzheimer's disease 43 | 658
astrocytoma 41 | 1,146
breast carcinoma 41 | 1,638
Epilepsy 40 | 792
Autosomal recessive predisposition 39 | 1,442
Dermatitis 38 | 157
ductal carcinoma in situ 38 | 1,745
Multiple Sclerosis 37 | 540
ulcerative colitis 37 | 1,819
Kidney disease 36 | 430
Behcet's syndrome 35 | 50
Congenital adrenal hyperplasia 35 | 73
Nephritis 35 | 51
Parkinson's disease 35 | 392
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
Synovitis 35 | 78
Takayasu's arteritis 35 | 53
drug-induced hepatitis 35 | 44
Bipolar Disorder 34 | 666
Anemia 33 | 365
juvenile dermatomyositis 33 | 1,187
Intellectual disability 32 | 1,016
Liver disease 32 | 237
colon cancer 32 | 1,478
cystic fibrosis 31 | 1,696
acute quadriplegic myopathy 30 | 1,158
Hepatitis B 28 | 108
Depressive disorder 27 | 409
pancreatic carcinoma 27 | 562
primary pancreatic ductal adenocarcinoma 27 | 1,109
spina bifida 27 | 1,074
adrenocortical carcinoma 26 | 1,428
cutaneous lupus erythematosus 26 | 1,057
Leprosy 25 | 73
Mental Depression 25 | 333
active Crohn's disease 25 | 922
Neurodegenerative disease 24 | 414
pediatric high grade glioma 24 | 1,064
Hemochromatosis 23 | 54
Obesity 23 | 678
Seizures 23 | 596
Skin disease 23 | 66
Waldenstrons macroglobulinemia 23 | 765
Duchenne muscular dystrophy 22 | 601
esophageal adenocarcinoma 22 | 737
Low intelligence 21 | 645
Mental Retardation 21 | 645
Mental deficiency 21 | 645
Poor school performance 21 | 645

Tissue

Endocrine System 351 | 18,159
Digestive Tract 350 | 17,369
Female tissues 347 | 17,400
Skin and soft tissues 345 | 17,230
Nervous System 344 | 16,725
Liver and Pancreas 343 | 16,750
Male tissues 341 | 17,142
Respiratory system 335 | 16,393
Urinary Tract 335 | 16,678
Blood and immune system 333 | 16,909
Cardiovascular System 314 | 15,192

Target Family

Non-IDG 345 | 12,091
Enzyme 55 | 4,145
Transporter 15 | 473
Ion Channel 5 | 344
Kinase 5 | 634
oGPCR 4 | 421
Transcription Factor 3 | 1,400
GPCR 2 | 408
Epigenetic 1 | 242

Compartment GO Term

Transport vesicle 435 | 435
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Annexin A13 ANXA13 Tbio Non-IDG -1.19458 15.6 162
GTP-binding protein SAR1b SAR1B Tbio Enzyme -1.91051 79.7 184
Probable ergosterol biosynthetic protein 28 ERG28 Tdark Non-IDG -1.25331 16.7 40
Stonin-2 STON2 Tbio Non-IDG -1.43585 30.0 11
Neuroendocrine secretory protein 55 GNAS Tbio Non-IDG -2.63356 1389.7 509
HLA class I histocompatibility antigen, A-25 alpha chain HLA-A Tbio Non-IDG -2.41667 4123.8 0
HLA class I histocompatibility antigen, B-51 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
Endothelin-1 EDN1 Tbio Non-IDG -4.07520 12851.9 607
Synaptic vesicle 2-related protein SVOP Tdark Non-IDG -0.57678 4.35 90
Sialin SLC17A5 Tbio Transporter -2.93541 845.6 63