Development Level

Tbio 25 | 11,445
Tchem 3 | 1,598

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal behavioral response t... 1 | 66
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal neural tube closure 1 | 46
abnormal spleen morphology 1 | 55
decreased bone mineral content 1 | 151
decreased circulating glucose ... 1 | 126
decreased granulocyte number 1 | 6
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hemorrhage 1 | 23
increased bone mineral content 1 | 108
increased total body fat amoun... 1 | 134
increased urine magnesium leve... 1 | 2
prenatal lethality prior to he... 1 | 87

Disease

ovarian cancer 23 | 8,520
Carcinoma 19 | 11,493
lung cancer 13 | 4,740
Multiple myeloma 12 | 1,332
medulloblastoma, large-cell 10 | 6,241
osteosarcoma 10 | 7,950
psoriasis 10 | 6,694
Cancer 9 | 2,499
glioblastoma 9 | 5,792
Breast cancer 8 | 3,578
group 3 medulloblastoma 8 | 4,104
atypical teratoid / rhabdoid tumor 7 | 5,112
non-small cell lung cancer 7 | 2,890
Waldenstrons macroglobulinemia 6 | 765
acute quadriplegic myopathy 6 | 1,158
diabetes mellitus 6 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
oligodendroglioma 6 | 2,850
adult high grade glioma 5 | 3,801
ependymoma 5 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
pancreatic cancer 5 | 2,398
primitive neuroectodermal tumor 5 | 3,035
Kidney cancer 4 | 2,613
astrocytoma 4 | 1,146
colon cancer 4 | 1,478
dermatomyositis 4 | 966
lung adenocarcinoma 4 | 2,716
malignant mesothelioma 4 | 3,232
primary pancreatic ductal adenocarcinoma 4 | 1,109
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis and treatment for 3 months 4 | 179
Astrocytoma, Pilocytic 3 | 3,081
HIV Infections 3 | 102
Leukoencephalopathy with vanishing white matter 3 | 20
Pick disease 3 | 1,894
acute myeloid leukemia 3 | 783
hereditary spastic paraplegia 3 | 318
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Adenocarcinoma of lung 2 | 142
Breast Neoplasms 2 | 445
Duchenne muscular dystrophy 2 | 601
Fragile X-associated tremor/ataxia syndrome 2 | 6
Lymphoma, Mantle-Cell 2 | 11
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse 2 | 12
Mammary Neoplasms 2 | 425
Retinitis pigmentosa 29 2 | 6
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Spinocerebellar ataxia type 2 2 | 23
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
gastric carcinoma 2 | 807
group 4 medulloblastoma 2 | 1,855
invasive ductal carcinoma 2 | 2,951
juvenile dermatomyositis 2 | 1,187
medulloblastoma 2 | 720
mucosa-associated lymphoid tissue lymphoma 2 | 484
sonic hedgehog group medulloblastoma 2 | 467
spina bifida 2 | 1,074
substance-related disorder 2 | 162
tuberculosis 2 | 2,010
Alcoholic Intoxication 1 | 34
Alzheimer Disease 1 | 83
Autistic Disorder 1 | 364
Big calvaria 1 | 147
Bladder Neoplasm 1 | 112
Carcinoma, Transitional Cell 1 | 32
Cardiovascular system disease 1 | 246
Cataract 7 1 | 32
Colorectal Neoplasms 1 | 243
Cystic lymphangioma 1 | 19
Disease Models, Animal 1 | 155
Disease of metabolism 1 | 18
Dysarthria 1 | 192
Globe disease 1 | 67
Hypersensitivity 1 | 63
Increased head circumference 1 | 147
Increased size of cranium 1 | 147
Increased size of skull 1 | 147
Inflammation 1 | 120
Leukoencephalopathies 1 | 29
Mental deterioration in childhood 1 | 95
Microcephaly 1 | 166
Neoplasm Metastasis 1 | 168
Nerve Degeneration 1 | 121
Neurodevelopmental regression 1 | 95
Pilocytic astrocytoma 1 | 56
Pneumonia 1 | 174
Psychomotor regression 1 | 95
Psychomotor regression beginning in infancy 1 | 95
Psychomotor regression in infants 1 | 95
Psychomotor regression, progressive 1 | 95
Trichorhinophalangeal syndrome type II 1 | 15
Urinary Bladder Neoplasms 1 | 114
Vestibular neuronitis 1 | 3
posterior fossa group A ependymoma 1 | 468
sarcoidosis 1 | 370
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 28 | 16,909
Cardiovascular System 28 | 15,192
Digestive Tract 28 | 17,369
Endocrine System 28 | 18,159
Female tissues 28 | 17,400
Liver and Pancreas 28 | 16,750
Male tissues 28 | 17,142
Nervous System 28 | 16,725
Respiratory system 28 | 16,393
Skin and soft tissues 28 | 17,230
Urinary Tract 28 | 16,678

Target Family

Non-IDG 25 | 12,091
Enzyme 1 | 4,145
Kinase 1 | 634
Transporter 1 | 473

Compartment GO Term

Translation initiation complex 28 | 28
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Eukaryotic translation initiation factor 1 EIF1 Tbio Non-IDG -2.06392 118.5 92
MAP kinase-interacting serine/threonine-protein kinase 1 MKNK1 Tchem Kinase -1.71576 46.7 408
Eukaryotic translation initiation factor 3 subunit C EIF3C Tbio Non-IDG -1.20680 14.1 159
Eukaryotic translation initiation factor 3 subunit B EIF3B Tbio Non-IDG -1.83618 70.5 84
ATP-binding cassette sub-family F member 1 ABCF1 Tbio Transporter -1.16255 15.7 212
Eukaryotic translation initiation factor 3 subunit J EIF3J Tbio Non-IDG -1.02121 10.3 106
ATP-dependent RNA helicase DHX29 DHX29 Tbio Enzyme -1.00971 9.60 76
Eukaryotic translation initiation factor 5 EIF5 Tbio Non-IDG -1.93055 83.2 159
Eukaryotic translation initiation factor 5B EIF5B Tbio Non-IDG -2.74742 528.3 124
Nuclear cap-binding protein subunit 1 NCBP1 Tbio Non-IDG -2.34134 207.7 172