Development Level

Tbio 8 | 11,445
Tchem 4 | 1,598

IMPC Phenotype

abnormal testis morphology 1 | 43
decreased eosinophil cell numb... 1 | 24
edema 1 | 59
enlarged lymph nodes 1 | 37
male infertility 1 | 123
preweaning lethality, complete... 1 | 979
small testis 1 | 58

Disease

Cancer 12 | 2,499
Carcinoma 10 | 11,493
ovarian cancer 10 | 8,520
Breast cancer 8 | 3,578
ependymoma 8 | 4,679
glioblastoma 8 | 5,792
Colorectal Neoplasms 7 | 243
Hypertensive disease 7 | 292
Kidney cancer 7 | 2,613
Acquired scoliosis 6 | 281
Aortic Valve Insufficiency 6 | 40
Byzanthine arch palate 6 | 194
Coronary artery disease 6 | 268
Curvature of spine 6 | 282
Increase in blood pressure 6 | 119
Loeys-Dietz syndrome 6 | 23
Orbital separation excessive 6 | 244
Pulmonary Fibrosis 6 | 106
Ureteral obstruction 6 | 33
atypical teratoid / rhabdoid tumor 6 | 5,112
group 3 medulloblastoma 6 | 4,104
lung cancer 6 | 4,740
medulloblastoma, large-cell 6 | 6,241
osteosarcoma 6 | 7,950
Abdominal Pain 5 | 98
Abnormality of the iris 5 | 14
Acquired flat foot 5 | 72
Adenoma 5 | 167
Aortic aneurysm, familial thoracic 3 5 | 13
Arachnodactyly 5 | 49
Ascending aortic dissection 5 | 13
Astrocytoma, Pilocytic 5 | 3,081
Cardiomegaly 5 | 116
Chest Pain 5 | 38
Cleft Palate 5 | 271
Craniofacial Abnormalities 5 | 151
Cutis marmorata 5 | 32
Cystic medial necrosis of aorta 5 | 13
Depressive disorder 5 | 409
Descending aortic dissection 5 | 13
Dyspnea on exertion 5 | 24
Dyspnea, Paroxysmal 5 | 13
Epilepsy 5 | 792
Familial thoracic aortic aneurysm and aortic dissection 5 | 13
Flatfoot 5 | 73
Impaired left ventricular function 5 | 16
Intermittent migraine headaches 5 | 68
Left-Sided Heart Failure 5 | 16
Liver Cirrhosis, Experimental 5 | 769
Loeys-Dietz Aortic Aneurysm Syndrome 5 | 13
Malabsorption 5 | 82
Migraine Disorders 5 | 76
Seizures 5 | 596
diabetes mellitus 5 | 1,728
malignant mesothelioma 5 | 3,232
pancreatic cancer 5 | 2,398
psoriasis 5 | 6,694
Anxiety 4 | 136
Anxiety disease 4 | 113
Aortic aneurysm 4 | 38
Arterial tortuosity 4 | 5
Attention deficit hyperactivity disorder 4 | 278
Constipation 4 | 181
Death in early adulthood 4 | 24
Death in early childhood 4 | 82
Death in infancy 4 | 82
Dissection of aorta 4 | 9
Dyschezia 4 | 135
Exophthalmos 4 | 112
Familial adenomatous polyposis 4 | 32
Fatigue 4 | 182
Gastrointestinal Hemorrhage 4 | 52
Hereditary Nonpolyposis Colorectal Cancer 4 | 11
Hernia, Inguinal 4 | 89
Intracranial hypertension 4 | 32
Irritation - emotion 4 | 68
Kidney disease 4 | 430
Liver Cirrhosis 4 | 181
Lynch syndrome 4 | 35
Malignant tumor of colon 4 | 19
Muscle Hypertonia 4 | 88
Muscle hypotonia 4 | 571
Nausea and vomiting 4 | 97
Neoplasm Metastasis 4 | 168
Prominent eyes 4 | 96
Prominent globes 4 | 96
Protruding eyes 4 | 96
Rectal Neoplasms 4 | 18
Stomach Neoplasms 4 | 300
Tall stature 4 | 34
Thoracic aortic aneurysm 4 | 15
Weight decreased 4 | 103
acute quadriplegic myopathy 4 | 1,158
adult high grade glioma 4 | 3,801
breast carcinoma 4 | 1,638
dermatomyositis 4 | 966
lung adenocarcinoma 4 | 2,716
lung carcinoma 4 | 2,843
subependymal giant cell astrocytoma 4 | 2,287
Inflammatory bowel disease 3 | 151

Tissue

Blood and immune system 12 | 16,909
Cardiovascular System 12 | 15,192
Digestive Tract 12 | 17,369
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678

Target Family

Non-IDG 5 | 12,091
Transcription Factor 4 | 1,400
Kinase 2 | 634
Enzyme 1 | 4,145

Compartment GO Term

Transforming growth factor bet... 12 | 12
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tchem Enzyme -3.80300 6069.9 574
Transforming growth factor beta-2 TGFB2 Tbio Non-IDG -3.14427 1378.3 384
Transforming growth factor beta-3 TGFB3 Tbio Non-IDG -3.02749 1062.5 308
DNA mismatch repair protein Mlh1 MLH1 Tbio Non-IDG -3.34283 2352.6 495
Mothers against decapentaplegic homolog 4 SMAD4 Tbio Transcription Factor -3.16129 1349.8 605
TGF-beta receptor type-2 TGFBR2 Tchem Kinase -2.84120 665.1 548
Mothers against decapentaplegic homolog 3 SMAD3 Tbio Transcription Factor -3.19667 1403.6 1526
Mothers against decapentaplegic homolog 7 SMAD7 Tbio Transcription Factor -2.81953 638.7 387
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -3.84680 5672.0 1222
TGF-beta receptor type-1 TGFBR1 Tchem Kinase -2.94747 847.9 413