Development Level

Tbio 148 | 11,445
Tchem 58 | 1,598
Tclin 21 | 613
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 16 | 979
embryonic lethality prior to t... 9 | 278
enlarged heart 9 | 210
preweaning lethality, incomple... 7 | 499
abnormal heart morphology 5 | 162
decreased vertical activity 5 | 208
embryonic lethality prior to o... 5 | 239
abnormal bone structure 4 | 187
abnormal embryo size 4 | 220
abnormal lung morphology 4 | 26
abnormal seminal vesicle morph... 4 | 114
abnormal testis morphology 3 | 43
decreased body weight 3 | 161
decreased bone mineral content 3 | 151
decreased total body fat amoun... 3 | 207
increased bone mineral content 3 | 108
increased heart weight 3 | 62
increased neutrophil cell numb... 3 | 46
limb grasping 3 | 41
small superior vagus ganglion 3 | 74
abnormal coat-hair pigmentatio... 2 | 64
abnormal cranium morphology 2 | 36
abnormal eye morphology 2 | 68
abnormal femur morphology 2 | 14
abnormal head morphology 2 | 10
abnormal humerus morphology 2 | 11
abnormal liver morphology 2 | 17
abnormal tooth morphology 2 | 24
decreased body length 2 | 101
decreased circulating HDL chol... 2 | 68
decreased circulating aspartat... 2 | 34
decreased circulating choleste... 2 | 93
decreased circulating creatini... 2 | 39
decreased circulating insulin ... 2 | 76
decreased erythrocyte cell num... 2 | 62
decreased heart weight 2 | 27
decreased lean body mass 2 | 135
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
decreased startle reflex 2 | 75
enlarged uterus 2 | 11
hydrometra 2 | 53
impaired righting response 2 | 26
increased bone mineral density 2 | 72
increased leukocyte cell numbe... 2 | 47
increased lymphocyte cell numb... 2 | 32
increased mean corpuscular vol... 2 | 92
increased monocyte cell number 2 | 63
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
short tibia 2 | 97
small testis 2 | 58
abnormal behavioral response t... 1 | 66
abnormal coat- hair morphology 1 | 19
abnormal craniofacial morpholo... 1 | 33
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal urinary bladder morph... 1 | 11
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
anophthalmia 1 | 33
cataract 1 | 92
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased circulating calcium ... 1 | 36
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased eosinophil cell numb... 1 | 24
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
dilated heart left ventricle 1 | 11
edema 1 | 59
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased circulating alkaline... 1 | 122
increased eosinophil cell numb... 1 | 11
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased prepulse inhibition 1 | 32
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
small spleen 1 | 19
trunk curl 1 | 16

Disease

Cancer 184 | 2,499
Carcinoma 146 | 11,493
psoriasis 132 | 6,694
ovarian cancer 128 | 8,520
lung cancer 119 | 4,740
glioblastoma 111 | 5,792
osteosarcoma 106 | 7,950
malignant mesothelioma 93 | 3,232
Breast cancer 91 | 3,578
diabetes mellitus 86 | 1,728
interstitial cystitis 85 | 2,312
invasive ductal carcinoma 85 | 2,951
atypical teratoid / rhabdoid tumor 82 | 5,112
lung carcinoma 81 | 2,843
non-small cell lung cancer 78 | 2,890
Kidney disease 77 | 430
medulloblastoma, large-cell 76 | 6,241
intraductal papillary-mucinous adenoma (IPMA) 75 | 2,955
tuberculosis 75 | 2,010
ependymoma 74 | 4,679
pancreatic cancer 74 | 2,398
ulcerative colitis 73 | 1,819
adult high grade glioma 72 | 3,801
Astrocytoma, Pilocytic 70 | 3,081
lung adenocarcinoma 70 | 2,716
cystic fibrosis 68 | 1,696
Asthma 66 | 385
Hypersensitivity reaction type II disease 65 | 253
Arthritis 64 | 290
Heart disease 58 | 306
Inflammatory bowel disease 58 | 151
intraductal papillary-mucinous carcinoma (IPMC) 57 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 57 | 3,291
Atherosclerosis 56 | 291
Lung disease 55 | 142
ductal carcinoma in situ 54 | 1,745
Liver Cirrhosis, Experimental 53 | 769
Liver disease 53 | 237
Schizophrenia 53 | 1,160
Multiple Sclerosis 52 | 540
breast carcinoma 52 | 1,638
Breast Neoplasms 51 | 445
Rheumatoid arthritis 51 | 1,191
Mammary Neoplasms 50 | 425
Obesity 50 | 678
Hypertension 48 | 396
Coronary artery disease 46 | 268
Pulmonary Fibrosis 45 | 106
oligodendroglioma 45 | 2,850
group 3 medulloblastoma 44 | 4,104
Dermatitis 43 | 157
pituitary cancer 43 | 1,972
primitive neuroectodermal tumor 43 | 3,035
colon cancer 42 | 1,478
cutaneous lupus erythematosus 42 | 1,057
Autosomal recessive predisposition 41 | 1,442
Vascular disease 41 | 319
subependymal giant cell astrocytoma 41 | 2,287
Allergic hypersensitivity disease 40 | 126
Hypertensive disease 40 | 292
Anemia 39 | 365
Endometriosis 39 | 540
Prostatic Neoplasms 39 | 495
nasopharyngeal carcinoma 39 | 1,058
Cerebrovascular disease 38 | 238
Kidney cancer 38 | 2,613
Neoplasm Metastasis 38 | 168
Stomach Neoplasms 38 | 300
Osteoporosis 37 | 363
Inflammation 35 | 120
pancreatic ductal adenocarcinoma liver metastasis 35 | 1,962
Atopic dermatitis 34 | 952
Carcinoma, Hepatocellular 34 | 228
juvenile dermatomyositis 34 | 1,187
Liver carcinoma 33 | 240
Lung Neoplasms 33 | 232
adrenocortical carcinoma 33 | 1,428
primary pancreatic ductal adenocarcinoma 33 | 1,109
Pneumonia 32 | 174
group 4 medulloblastoma 32 | 1,855
periodontitis 32 | 293
Alzheimer's disease 31 | 658
Duchenne muscular dystrophy 31 | 601
Liver Cirrhosis 31 | 181
Osteoarthritis 31 | 184
sarcoidosis 31 | 370
Hypereosinophilic syndrome 30 | 71
Influenza 30 | 142
astrocytic glioma 30 | 2,597
gastric carcinoma 30 | 807
Hyperglycemia 29 | 137
Neoplasm Invasiveness 29 | 161
Reperfusion Injury 29 | 86
Short stature 29 | 531
autosomal dominant Emery-Dreifuss muscular dystrophy 29 | 510
Depressive disorder 28 | 409
Major Depressive Disorder 28 | 301
Melanoma 28 | 711
Neuropathy 28 | 261
esophageal adenocarcinoma 28 | 737

Tissue

Endocrine System 220 | 18,159
Digestive Tract 218 | 17,369
Skin and soft tissues 217 | 17,230
Urinary Tract 215 | 16,678
Blood and immune system 214 | 16,909
Liver and Pancreas 214 | 16,750
Male tissues 214 | 17,142
Female tissues 212 | 17,400
Respiratory system 211 | 16,393
Nervous System 205 | 16,725
Cardiovascular System 191 | 15,192

Target Family

Non-IDG 149 | 12,091
Transcription Factor 27 | 1,400
Enzyme 25 | 4,145
Kinase 23 | 634
GPCR 2 | 408
Nuclear Receptor 2 | 48
Epigenetic 1 | 242

Compartment GO Term

Transforming growth factor bet... 229 | 229
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
T-box transcription factor TBX21 TBX21 Tbio Transcription Factor -2.95359 868.5 480
Growth/differentiation factor 15 GDF15 Tbio Non-IDG -2.84344 761.3 702
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Growth/differentiation factor 2 GDF2 Tbio Non-IDG -2.16825 176.4 239
Activin receptor type-2A ACVR2A Tchem Kinase -2.08745 108.0 315
Latent-transforming growth factor beta-binding protein 1 LTBP1 Tbio Non-IDG -1.97590 101.5 128
C-C motif chemokine 20 CCL20 Tbio Non-IDG -3.10283 1250.3 496
Putative teratocarcinoma-derived growth factor 3 TDGF1P3 Tdark Non-IDG -1.99746 160.4 0
Interferon alpha-1/13 IFNA13 Tbio Non-IDG -3.87160 7663.4 500
Parathyroid hormone-related protein PTHLH Tbio Non-IDG -3.27676 2151.5 283