Development Level

Tbio 109 | 11,445
Tchem 16 | 1,598
Tclin 5 | 613
Tdark 3 | 6,588

IMPC Phenotype

preweaning lethality, complete... 14 | 979
preweaning lethality, incomple... 7 | 499
abnormal behavior 3 | 298
decreased bone mineral density 3 | 126
decreased vertical activity 3 | 208
enlarged heart 3 | 210
increased mean corpuscular hem... 3 | 96
increased startle reflex 3 | 112
abnormal bone mineralization 2 | 38
decreased body weight 2 | 161
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased circulating triglyce... 2 | 79
decreased total body fat amoun... 2 | 207
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
increased body weight 2 | 25
increased circulating triglyce... 2 | 42
increased lean body mass 2 | 172
increased total body fat amoun... 2 | 134
microphthalmia 2 | 26
small spleen 2 | 19
thrombocytopenia 2 | 56
trunk curl 2 | 16
abnormal cecum morphology 1 | 7
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal head morphology 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal maxilla morphology 1 | 17
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal thymus morphology 1 | 7
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
abnormal vocalization 1 | 21
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating calcium ... 1 | 36
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating insulin ... 1 | 76
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased threshold for audito... 1 | 26
decreased total retina thickne... 1 | 17
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged spleen 1 | 41
improved glucose tolerance 1 | 79
increased body length 1 | 32
increased body temperature 1 | 9
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating glycerol... 1 | 9
increased hemoglobin content 1 | 45
increased lymphocyte cell numb... 1 | 32
increased prepulse inhibition 1 | 32
long tibia 1 | 25
mammalian phenotype 1 | 17
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
small heart 1 | 10
small kidney 1 | 16
small liver 1 | 8
small lung 1 | 5
small superior vagus ganglion 1 | 74
small thymus 1 | 16
thin ventricular wall 1 | 24
thrombocytosis 1 | 27
tremors 1 | 39
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

Carcinoma 101 | 11,493
osteosarcoma 81 | 7,950
ovarian cancer 79 | 8,520
Cancer 68 | 2,499
psoriasis 65 | 6,694
medulloblastoma, large-cell 63 | 6,241
glioblastoma 61 | 5,792
atypical teratoid / rhabdoid tumor 55 | 5,112
ependymoma 50 | 4,679
lung cancer 48 | 4,740
Breast cancer 46 | 3,578
group 3 medulloblastoma 46 | 4,104
primitive neuroectodermal tumor 40 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 39 | 2,989
malignant mesothelioma 38 | 3,232
adult high grade glioma 35 | 3,801
invasive ductal carcinoma 34 | 2,951
Astrocytoma, Pilocytic 31 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 31 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 30 | 3,291
Kidney cancer 29 | 2,613
oligodendroglioma 29 | 2,850
lung adenocarcinoma 28 | 2,716
non-small cell lung cancer 27 | 2,890
pancreatic cancer 27 | 2,398
astrocytic glioma 26 | 2,597
subependymal giant cell astrocytoma 26 | 2,287
lung carcinoma 24 | 2,843
Intellectual disability 21 | 1,016
Rheumatoid arthritis 21 | 1,191
pituitary cancer 21 | 1,972
tuberculosis 21 | 2,010
adrenocortical carcinoma 20 | 1,428
astrocytoma 20 | 1,146
group 4 medulloblastoma 20 | 1,855
interstitial cystitis 20 | 2,312
juvenile dermatomyositis 20 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,962
pediatric high grade glioma 18 | 1,064
Pick disease 17 | 1,894
acute myeloid leukemia 17 | 783
breast carcinoma 17 | 1,638
Breast Neoplasms 16 | 445
Mammary Neoplasms 16 | 425
acute quadriplegic myopathy 16 | 1,158
cystic fibrosis 16 | 1,696
Dull intelligence 15 | 645
Low intelligence 15 | 645
Mental Retardation 15 | 645
Mental deficiency 15 | 645
Poor school performance 15 | 645
Prostatic Neoplasms 15 | 495
gastric carcinoma 15 | 807
primary pancreatic ductal adenocarcinoma 15 | 1,109
Small head 14 | 374
ulcerative colitis 14 | 1,819
Epilepsy 13 | 792
Multiple myeloma 13 | 1,332
ductal carcinoma in situ 13 | 1,745
Muscle hypotonia 12 | 571
Neoplasm Invasiveness 12 | 161
Schizophrenia 12 | 1,160
Seizures 12 | 596
Short stature 12 | 531
diabetes mellitus 12 | 1,728
nasopharyngeal carcinoma 12 | 1,058
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 510
colon cancer 11 | 1,478
primary Sjogren syndrome 11 | 735
Alzheimer's disease 10 | 658
Cell Transformation, Neoplastic 10 | 97
Immune system cancer 10 | 140
Waldenstrons macroglobulinemia 10 | 765
Atopic dermatitis 9 | 952
Endometrial cancer 9 | 311
Liver cancer 9 | 604
Neoplastic Cell Transformation 9 | 89
Stomach Neoplasms 9 | 300
Strabismus 9 | 270
aldosterone-producing adenoma 9 | 665
medulloblastoma 9 | 720
Acquired scoliosis 8 | 281
Cognitive delay 8 | 608
Colorectal Neoplasms 8 | 243
Concave bridge of nose 8 | 195
Congenital Epicanthus 8 | 177
Cryptorchidism 8 | 296
Curvature of spine 8 | 282
Depressed nasal bridge 8 | 195
Depressed nasal root/bridge 8 | 195
Disease Progression 8 | 136
Endometriosis 8 | 540
Global developmental delay 8 | 608
Long philtrum 8 | 137
Lymphoid leukemia 8 | 160
Mental and motor retardation 8 | 608
Neoplasm Metastasis 8 | 168
Vascular disease 8 | 319
cutaneous lupus erythematosus 8 | 1,057
hepatocellular carcinoma 8 | 547

Tissue

Endocrine System 130 | 18,159
Digestive Tract 129 | 17,369
Blood and immune system 128 | 16,909
Female tissues 128 | 17,400
Liver and Pancreas 128 | 16,750
Male tissues 128 | 17,142
Skin and soft tissues 128 | 17,230
Nervous System 127 | 16,725
Urinary Tract 127 | 16,678
Respiratory system 126 | 16,393
Cardiovascular System 121 | 15,192

Target Family

Transcription Factor 68 | 1,400
Non-IDG 38 | 12,091
Epigenetic 16 | 242
Enzyme 5 | 4,145
TF/Epigenetic 4 | 38
Ion Channel 1 | 344
Nuclear Receptor 1 | 48

Compartment GO Term

Transcriptional repressor comp... 133 | 133
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Methyl-CpG-binding domain protein 3 MBD3 Tbio Transcription Factor -0.85800 7.92 309
Zinc finger protein 346 ZNF346 Tbio Non-IDG -2.28393 188.7 213
Dr1-associated corepressor DRAP1 Tbio Non-IDG -1.11644 10.8 122
Hairy/enhancer-of-split related with YRPW motif protein 1 HEY1 Tbio Transcription Factor -2.28398 163.4 335
Forkhead box protein D3 FOXD3 Tbio Transcription Factor -2.69659 482.7 180
Metastasis-associated protein MTA3 MTA3 Tbio Transcription Factor -1.36174 24.5 204
PHD finger protein 12 PHF12 Tbio Epigenetic -2.57717 385.3 70
Bromodomain adjacent to zinc finger domain protein 2A BAZ2A Tchem TF/Epigenetic -2.07564 115.2 51
Chromodomain-helicase-DNA-binding protein 4 CHD4 Tbio Epigenetic -2.22229 159.7 203
DNA endonuclease RBBP8 RBBP8 Tbio Enzyme -2.17933 148.4 308