Development Level

Tbio 43 | 10,625
Tchem 5 | 1,890
Tdark 3 | 7,003

IMPC Phenotype

preweaning lethality, complete... 6 | 633
embryonic lethality prior to o... 4 | 148
embryonic lethality prior to t... 3 | 187
abnormal retina morphology 2 | 100
increased exploration in new e... 2 | 56
abnormal behavioral response t... 1 | 52
abnormal coat appearance 1 | 25
abnormal spleen morphology 1 | 36
abnormal tail bud morphology 1 | 6
decreased caudal vertebrae num... 1 | 49
decreased circulating calcium ... 1 | 33
decreased circulating glucose ... 1 | 121
decreased lean body mass 1 | 195
decreased threshold for audito... 1 | 32
hypoactivity 1 | 89
increased circulating potassiu... 1 | 31
increased fasted circulating g... 1 | 68
increased or absent threshold ... 1 | 128

Disease

ovarian cancer 30 | 8,491
osteosarcoma 28 | 7,933
lung cancer 16 | 4,473
psoriasis 16 | 6,685
Cancer 11 | 2,346
medulloblastoma, large-cell 10 | 6,234
Multiple myeloma 9 | 1,327
glioblastoma 9 | 5,572
Carcinoma 8 | 2,147
malignant mesothelioma 8 | 3,163
Breast cancer 7 | 3,098
Waldenstrons macroglobulinemia 7 | 764
diabetes mellitus 7 | 1,663
group 3 medulloblastoma 7 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,988
Pick disease 6 | 1,893
atypical teratoid / rhabdoid tumor 6 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,289
non-small cell lung cancer 6 | 2,798
colon cancer 5 | 1,475
dermatomyositis 5 | 966
ependymoma 5 | 2,514
lung adenocarcinoma 5 | 2,714
pancreatic cancer 5 | 2,300
pediatric high grade glioma 5 | 2,712
primitive neuroectodermal tumor 5 | 3,031
subependymal giant cell astrocytoma 5 | 2,287
Cockayne syndrome 4 | 54
Epidermodysplasia verruciformis 4 | 21
Rheumatoid Arthritis 4 | 1,170
oligodendroglioma 4 | 2,849
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
Intellectual disability 3 | 573
Peripheral Neuropathy 3 | 303
Photosensitive trichothiodystrophy 3 | 24
Xeroderma pigmentosum 3 | 41
acute myeloid leukemia 3 | 785
acute quadriplegic myopathy 3 | 1,157
adult high grade glioma 3 | 2,148
astrocytoma 3 | 1,493
ductal carcinoma in situ 3 | 1,745
gastric cancer 3 | 436
group 4 medulloblastoma 3 | 1,875
hepatocellular carcinoma 3 | 550
invasive ductal carcinoma 3 | 2,950
juvenile dermatomyositis 3 | 1,189
pancreatic carcinoma 3 | 567
pilocytic astrocytoma 3 | 3,086
tuberculosis 3 | 1,563
tuberculosis and treatment for 6 months 3 | 686
Dystonia 2 | 77
HIV Infections 2 | 99
Mixed connective tissue disease 2 | 16
Neurodegenerative disease 2 | 383
Parkinson's disease 2 | 364
Rothmund-Thomson syndrome 2 | 22
Spinocerebellar ataxia type 2 2 | 19
active Crohn's disease 2 | 918
aldosterone-producing adenoma 2 | 664
astrocytic glioma 2 | 2,241
atypical teratoid/rhabdoid tumor 2 | 1,095
gastric carcinoma 2 | 832
glioblastoma multiforme 2 | 347
hereditary spastic paraplegia 2 | 313
medulloblastoma 2 | 1,524
nasopharyngeal carcinoma 2 | 1,056
posterior fossa group A ependymoma 2 | 1,511
progressive supranuclear palsy 2 | 674
sarcoidosis 2 | 368
tuberculosis and treatment for 3 months 2 | 327
Acute intermittent porphyria 1 | 14
Arsenic Poisoning 1 | 59
Autistic Disorder 1 | 320
Autosomal dominant cerebellar ataxia 1 | 34
Barrett's esophagus 1 | 185
Cerebellar Ataxia 1 | 72
Choreatic disease 1 | 27
Cystinosis 1 | 15
Dementia 1 | 129
Disease of metabolism 1 | 15
Disseminated intravascular coagulation 1 | 32
Familial atrial fibrillation 1 | 16
Gaucher disease type 1 1 | 171
Huntington's disease 1 | 72
Influenza 1 | 142
Machado-Joseph disease 1 | 18
Mammary Neoplasms 1 | 410
Meier-Gorlin syndrome 1 | 12
Melanoma 1 | 261
Microcephaly 1 | 149
Neoplasm Metastasis 1 | 138
Nerve Degeneration 1 | 73
Polycythemia 1 | 19
Skin cancer 1 | 37
Vaccinia 1 | 37
X-linked cerebral adrenoleukodystrophy 1 | 115
active ulcerative colitis 1 | 477
cone-rod dystrophy 1 | 60
dentatorubral-pallidoluysian atrophy 1 | 21

Tissue

Blood and immune system 49 | 17,994
Cardiovascular System 49 | 17,957
Female tissues 49 | 18,646
Liver and Pancreas 49 | 18,135
Male tissues 49 | 17,968
Nervous System 49 | 18,560
Urinary Tract 49 | 18,443
Digestive Tract 48 | 18,472
Endocrine System 48 | 18,511
Respiratory system 48 | 17,483
Skin and soft tissues 48 | 18,114

Target Family

Non-IDG 37 | 11,969
Enzyme 12 | 4,146
Kinase 2 | 634

Compartment GO Term

Transcriptional preinitiation ... 51 | 51
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
General transcription factor 3C polypeptide 1 GTF3C1 Tbio Non-IDG -2.19134 151.5 32
RNA polymerase I-specific transcription initiation factor RRN3 RRN3 Tbio Enzyme -1.47251 46.2 152
General transcription factor IIH subunit 3 GTF2H3 Tbio Non-IDG -0.87291 6.02 65
DNA polymerase iota POLI Tbio Enzyme -3.21852 1616.9 231
General transcription factor IIH subunit 1 GTF2H1 Tbio Non-IDG -1.64263 41.9 218
Transcription factor TFIIIB component B'' homolog BDP1 Tbio Non-IDG -2.22239 164.8 11
Eukaryotic translation initiation factor 2 subunit 1 EIF2S1 Tchem Non-IDG -2.80914 642.9 498
Eukaryotic translation initiation factor 4B EIF4B Tbio Non-IDG -2.00776 94.6 559
Cell division control protein 45 homolog CDC45 Tbio Non-IDG -2.08011 105.8 227
ATP-dependent RNA helicase DHX29 DHX29 Tbio Enzyme -0.98232 9.48 73