Development Level

Tbio 63 | 10,625
Tchem 9 | 1,890
Tdark 8 | 7,003

Collection

Kinase: IDG Consortium (Complete/Control) 2 | 37

IMPC Phenotype

preweaning lethality, complete... 11 | 633
embryonic lethality prior to o... 4 | 148
decreased lean body mass 3 | 195
decreased body length 2 | 108
decreased circulating serum al... 2 | 79
decreased lumbar vertebrae num... 2 | 62
decreased total body fat amoun... 2 | 186
embryonic lethality prior to t... 2 | 187
increased or absent threshold ... 2 | 128
increased sacral vertebrae num... 2 | 62
prenatal lethality prior to he... 2 | 64
abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal heart morphology 1 | 51
abnormal iris morphology 1 | 12
abnormal lens morphology 1 | 73
abnormal retina morphology 1 | 100
abnormal sacral vertebrae morp... 1 | 5
abnormal skin morphology 1 | 23
abnormal vertebral arch morpho... 1 | 9
cataract 1 | 26
decreased bone mineral content 1 | 157
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating amylase ... 1 | 24
decreased circulating fructosa... 1 | 31
decreased effector memory CD8-... 1 | 24
decreased grip strength 1 | 123
decreased mean corpuscular vol... 1 | 50
enlarged epididymis 1 | 27
enlarged heart 1 | 111
fusion of vertebral arches 1 | 7
increased circulating sodium l... 1 | 71
increased grip strength 1 | 83
malocclusion 1 | 1
preweaning lethality, incomple... 1 | 260
prolonged QRS complex duration 1 | 2
short tibia 1 | 82
thrombocytopenia 1 | 46
vertebral transformation 1 | 12

Disease

ovarian cancer 53 | 8,491
osteosarcoma 39 | 7,933
psoriasis 26 | 6,685
medulloblastoma, large-cell 22 | 6,234
Cancer 19 | 2,346
Carcinoma 18 | 2,147
glioblastoma 18 | 5,572
Multiple myeloma 17 | 1,327
lung cancer 17 | 4,473
atypical teratoid / rhabdoid tumor 14 | 4,369
malignant mesothelioma 14 | 3,163
Breast cancer 13 | 3,098
astrocytic glioma 12 | 2,241
diabetes mellitus 11 | 1,663
astrocytoma 10 | 1,493
oligodendroglioma 10 | 2,849
pituitary cancer 10 | 1,972
primitive neuroectodermal tumor 10 | 3,031
acute myeloid leukemia 9 | 785
ependymoma 9 | 2,514
pediatric high grade glioma 9 | 2,712
Cockayne syndrome 8 | 54
Waldenstrons macroglobulinemia 8 | 764
acute quadriplegic myopathy 8 | 1,157
adult high grade glioma 8 | 2,148
group 3 medulloblastoma 8 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,988
Pick disease 7 | 1,893
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,956
lung adenocarcinoma 7 | 2,714
non-small cell lung cancer 7 | 2,798
pancreatic cancer 7 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,795
ulcerative colitis 7 | 2,087
Rheumatoid Arthritis 6 | 1,170
dermatomyositis 6 | 966
group 4 medulloblastoma 6 | 1,875
interstitial cystitis 6 | 2,299
medulloblastoma 6 | 1,524
progressive supranuclear palsy 6 | 674
Intellectual disability 5 | 573
Leukemia 5 | 88
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
lung carcinoma 5 | 2,844
non primary Sjogren syndrome sicca 5 | 840
pilocytic astrocytoma 5 | 3,086
sonic hedgehog group medulloblastoma 5 | 1,482
subependymal giant cell astrocytoma 5 | 2,287
tuberculosis 5 | 1,563
Hemangioma 4 | 35
Wolf-Hirschhorn syndrome 4 | 32
colon cancer 4 | 1,475
juvenile dermatomyositis 4 | 1,189
nasopharyngeal carcinoma 4 | 1,056
posterior fossa group B ependymoma 4 | 1,530
primary pancreatic ductal adenocarcinoma 4 | 1,271
Acquired immunodeficiency syndrome 3 | 164
CHARGE syndrome 3 | 23
Cryptorchidism 3 | 67
Hypogonadism 3 | 70
Hypogonadotropic hypogonadism 3 | 20
Kallmann Syndrome 3 | 33
Klinefelter's syndrome 3 | 59
Lung Neoplasms 3 | 171
Malaria 3 | 140
Mammary Neoplasms 3 | 410
Photosensitive trichothiodystrophy 3 | 24
Renal Cell Carcinoma 3 | 199
Riley-Day syndrome 3 | 8
adrenocortical carcinoma 3 | 1,427
cystic fibrosis 3 | 1,670
invasive ductal carcinoma 3 | 2,950
spina bifida 3 | 1,064
tuberculosis and treatment for 3 months 3 | 327
tuberculosis and treatment for 6 months 3 | 686
Adenoma 2 | 165
Atopic dermatitis 2 | 944
Chondrodysplasia punctata 2 | 41
Cleft Lip 2 | 91
Cleft palate 2 | 125
Dermatitis, Allergic Contact 2 | 66
Gaucher disease type 1 2 | 171
Heart disease 2 | 279
Hypersensitivity reaction type II disease 2 | 235
Microcephaly 2 | 149
Multiple Sclerosis 2 | 498
Neurodegenerative disease 2 | 383
Prostatic Neoplasms 2 | 471
active Crohn's disease 2 | 918
aldosterone-producing adenoma 2 | 664
atypical teratoid/rhabdoid tumor 2 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
breast carcinoma 2 | 1,614
chronic lymphosyte leukemia 2 | 232
cutaneous lupus erythematosus 2 | 1,056
hepatocellular carcinoma 2 | 550
hereditary spastic paraplegia 2 | 313
pancreatic carcinoma 2 | 567
posterior fossa group A ependymoma 2 | 1,511
primary Sjogren syndrome 2 | 788

Tissue

Blood and immune system 80 | 17,994
Urinary Tract 80 | 18,443
Cardiovascular System 78 | 17,957
Digestive Tract 78 | 18,472
Endocrine System 78 | 18,511
Female tissues 78 | 18,646
Liver and Pancreas 78 | 18,135
Nervous System 78 | 18,560
Skin and soft tissues 77 | 18,114
Male tissues 76 | 17,968
Respiratory system 76 | 17,483

Target Family

Non-IDG 48 | 11,969
Enzyme 18 | 4,146
Transcription Factor 5 | 1,400
Epigenetic 4 | 242
Kinase 4 | 634
GPCR 1 | 408

Compartment GO Term

Transcription elongation facto... 80 | 80
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Von Hippel-Lindau disease tumor suppressor VHL Tchem Enzyme -2.45725 283.9 450
Protein IWS1 homolog IWS1 Tdark Non-IDG -0.56293 3.84 50
Protein HEXIM1 HEXIM1 Tchem Non-IDG -1.79179 61.2 311
Cyclin-dependent kinase 12 CDK12 Tbio Kinase -1.31357 24.3 152
Mediator of RNA polymerase II transcription subunit 26 MED26 Tbio Enzyme -1.12271 11.4 198
Negative elongation factor E NELFE Tbio Non-IDG -1.43797 27.6 85
ELL-associated factor 1 EAF1 Tdark Non-IDG 0.09 0.79 76
Zinc finger CCCH domain-containing protein 8 ZC3H8 Tbio Non-IDG 0.78 0.00000 142
RNA polymerase-associated protein RTF1 homolog RTF1 Tbio Enzyme -1.43176 28.7 124
RNA polymerase II transcription factor SIII subunit A3-like-1 ELOA3B Tdark Enzyme 0.70 0.20 1