Development Level

Tbio 63 | 11,445
Tdark 12 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 14 | 979
embryonic lethality prior to o... 8 | 239
embryonic lethality prior to t... 5 | 278
abnormal embryo size 4 | 220
decreased mean corpuscular hem... 3 | 50
abnormal behavioral response t... 2 | 66
abnormal cranium morphology 2 | 36
abnormal embryo turning 2 | 31
abnormal optic disc morphology 2 | 10
abnormal retina morphology 2 | 71
decreased caudal vertebrae num... 2 | 53
decreased circulating creatini... 2 | 39
decreased circulating triglyce... 2 | 79
decreased fasted circulating g... 2 | 65
embryonic growth retardation 2 | 106
hydrometra 2 | 53
increased circulating alkaline... 2 | 122
preweaning lethality, incomple... 2 | 499
short tibia 2 | 97
abnormal lens morphology 1 | 81
abnormal skin appearance 1 | 3
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal thoracic cage shape 1 | 3
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
convulsive seizures 1 | 13
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating serum al... 1 | 82
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased pulmonary respirator... 1 | 5
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
enlarged kidney 1 | 14
impaired glucose tolerance 1 | 75
increased anti-nuclear antigen... 1 | 19
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating iron lev... 1 | 30
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
male infertility 1 | 123
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

Carcinoma 54 | 11,493
ovarian cancer 49 | 8,520
osteosarcoma 44 | 7,950
psoriasis 24 | 6,694
medulloblastoma, large-cell 23 | 6,241
glioblastoma 18 | 5,792
atypical teratoid / rhabdoid tumor 14 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
adult high grade glioma 12 | 3,801
ependymoma 12 | 4,679
Kidney cancer 11 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
lung cancer 11 | 4,740
astrocytic glioma 10 | 2,597
diabetes mellitus 10 | 1,728
ARC syndrome 9 | 13
pancreatic cancer 9 | 2,398
Autosomal recessive predisposition 8 | 1,442
Congenital disorder of glycosylation 8 | 54
Multiple myeloma 8 | 1,332
Pick disease 8 | 1,894
Breast cancer 7 | 3,578
Cancer 7 | 2,499
Rheumatoid arthritis 7 | 1,191
group 3 medulloblastoma 7 | 4,104
group 4 medulloblastoma 7 | 1,855
subependymal giant cell astrocytoma 7 | 2,287
Astrocytoma, Pilocytic 6 | 3,081
Intellectual disability 6 | 1,016
hepatocellular carcinoma 6 | 547
lung carcinoma 6 | 2,843
non primary Sjogren syndrome sicca 6 | 891
oligodendroglioma 6 | 2,850
primitive neuroectodermal tumor 6 | 3,035
tuberculosis 6 | 2,010
Alzheimer's disease 5 | 658
Hypomyelinating leukodystrophy 6 5 | 26
acute quadriplegic myopathy 5 | 1,158
juvenile dermatomyositis 5 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Cognitive delay 4 | 608
Global developmental delay 4 | 608
Mental and motor retardation 4 | 608
Muscle hypotonia 4 | 571
Schizophrenia 4 | 1,160
Waldenstrons macroglobulinemia 4 | 765
astrocytoma 4 | 1,146
interstitial cystitis 4 | 2,312
malignant mesothelioma 4 | 3,232
primary pancreatic ductal adenocarcinoma 4 | 1,109
Amyotrophic lateral sclerosis 3 | 451
Autosomal dominant Robinow syndrome 2 3 | 22
Cutis Laxa 3 | 39
Dull intelligence 3 | 645
Liver Dysfunction 3 | 99
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Neurodegenerative disease 3 | 414
Obesity 3 | 678
Poor school performance 3 | 645
acute myeloid leukemia 3 | 783
cystic fibrosis 3 | 1,696
dermatomyositis 3 | 966
gastric cancer 3 | 459
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
pancreatic carcinoma 3 | 562
tuberculosis and treatment for 6 months 3 | 409
Acquired scoliosis 2 | 281
Atherosclerosis 2 | 291
Atopic dermatitis 2 | 952
Atrophy of cerebellum 2 | 103
Bipolar Disorder 2 | 666
Cerebellar degeneration 2 | 103
Cerebral atrophy 2 | 178
Cholestasis 2 | 155
Coronary artery disease 2 | 268
Curvature of spine 2 | 282
Hepatic enzyme increased 2 | 81
Hypothyroidism 2 | 122
Infratentorial atrophy 2 | 103
Kidney disease 2 | 430
Liver enzymes abnormal 2 | 81
Liver function test increased 2 | 81
Liver function tests abnormal finding 2 | 81
Myocardial Ischemia 2 | 169
Neuropathy 2 | 261
Parkinson's disease 2 | 392
Polycystic ovary syndrome 2 | 360
Transaminases increased 2 | 81
active ulcerative colitis 2 | 764
adrenocortical carcinoma 2 | 1,428
aldosterone-producing adenoma 2 | 665
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
progressive supranuclear palsy 2 | 676
spina bifida 2 | 1,074

Tissue

Blood and immune system 75 | 16,909
Female tissues 75 | 17,400
Skin and soft tissues 75 | 17,230
Digestive Tract 74 | 17,369
Endocrine System 74 | 18,159
Liver and Pancreas 74 | 16,750
Male tissues 74 | 17,142
Nervous System 74 | 16,725
Respiratory system 74 | 16,393
Urinary Tract 74 | 16,678
Cardiovascular System 73 | 15,192

Target Family

Non-IDG 64 | 12,091
Enzyme 9 | 4,145
Transcription Factor 2 | 1,400
Ion Channel 1 | 344

Compartment GO Term

Tethering complex 76 | 76
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,237 | 12,237
Intracellular organelle 12,023 | 12,023
membrane-bounded organelle 11,130 | 11,130
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,340 | 10,340
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,561 | 7,561
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,972 | 3,972
non-membrane-bounded organelle 3,972 | 3,972
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,955 | 1,955
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,547 | 1,547
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,123 | 1,123
Nuclear outer membrane-endopla... 1,121 | 1,121
Nucleoplasm part 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,040 | 1,040
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 949 | 949
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 848 | 848
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

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