Development Level

Tbio 127 | 11,445
Tchem 29 | 1,598
Tdark 8 | 6,588
Tclin 5 | 613

Collection

RFA-RM-18-021 3 | 328
Ion Channel: IDG Consortium (T... 2 | 99
GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 9 | 979
preweaning lethality, incomple... 8 | 499
embryonic lethality prior to t... 7 | 278
decreased circulating insulin ... 5 | 76
decreased vertical activity 5 | 208
embryonic lethality prior to o... 5 | 239
abnormal behavior 4 | 298
decreased total body fat amoun... 4 | 207
short tibia 4 | 97
enlarged lymph nodes 3 | 37
increased bone mineral content 3 | 108
increased circulating alkaline... 3 | 122
increased lean body mass 3 | 172
abnormal embryo size 2 | 220
abnormal lung morphology 2 | 26
abnormal seminal vesicle morph... 2 | 114
decreased circulating serum al... 2 | 82
embryonic growth retardation 2 | 106
hyperactivity 2 | 148
impaired glucose tolerance 2 | 75
increased bone mineral density 2 | 72
increased circulating triglyce... 2 | 42
increased leukocyte cell numbe... 2 | 47
small superior vagus ganglion 2 | 74
abnormal QT variability 1 | 10
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal thymus morphology 1 | 7
absent pinna reflex 1 | 23
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating lactate ... 1 | 3
decreased circulating phosphat... 1 | 27
decreased circulating triglyce... 1 | 79
decreased fluid intake 1 | 3
decreased food intake 1 | 13
decreased heart left ventricle... 1 | 28
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased respiratory quotient 1 | 16
decreased threshold for audito... 1 | 26
enlarged spleen 1 | 41
enlarged urinary bladder 1 | 8
fusion of vertebral arches 1 | 7
head bobbing 1 | 5
hydrometra 1 | 53
hypoactivity 1 | 132
impaired righting response 1 | 26
increased body temperature 1 | 9
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating free fat... 1 | 20
increased circulating glucose ... 1 | 24
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating thyroxin... 1 | 7
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
polysyndactyly 1 | 2
premature death 1 | 5
prenatal lethality 1 | 28
prolonged PR interval 1 | 15
small thymus 1 | 16
stereotypic behavior 1 | 3
thrombocytopenia 1 | 56
trunk curl 1 | 16
vertebral transformation 1 | 12

Disease

osteosarcoma 110 | 7,950
Carcinoma 102 | 11,493
ovarian cancer 97 | 8,520
lung cancer 74 | 4,740
psoriasis 70 | 6,694
glioblastoma 68 | 5,792
lung carcinoma 62 | 2,843
non-small cell lung cancer 61 | 2,890
medulloblastoma, large-cell 59 | 6,241
malignant mesothelioma 54 | 3,232
tuberculosis 51 | 2,010
interstitial cystitis 50 | 2,312
Breast cancer 48 | 3,578
pancreatic cancer 48 | 2,398
Cancer 47 | 2,499
lung adenocarcinoma 47 | 2,716
invasive ductal carcinoma 46 | 2,951
mucosa-associated lymphoid tissue lymphoma 46 | 484
atypical teratoid / rhabdoid tumor 43 | 5,112
ependymoma 41 | 4,679
subependymal giant cell astrocytoma 41 | 2,287
Astrocytoma, Pilocytic 40 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 40 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 40 | 3,291
adult high grade glioma 39 | 3,801
group 3 medulloblastoma 35 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 34 | 2,989
ulcerative colitis 34 | 1,819
diabetes mellitus 31 | 1,728
cystic fibrosis 29 | 1,696
Multiple myeloma 26 | 1,332
Kidney cancer 25 | 2,613
Liver Cirrhosis, Experimental 25 | 769
cutaneous lupus erythematosus 25 | 1,057
Waldenstrons macroglobulinemia 24 | 765
astrocytoma 23 | 1,146
oligodendroglioma 23 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 23 | 1,962
primary pancreatic ductal adenocarcinoma 23 | 1,109
primitive neuroectodermal tumor 23 | 3,035
Autosomal recessive predisposition 22 | 1,442
Rheumatoid arthritis 22 | 1,191
astrocytic glioma 21 | 2,597
dermatomyositis 21 | 966
juvenile dermatomyositis 21 | 1,187
breast carcinoma 20 | 1,638
colon cancer 19 | 1,478
ductal carcinoma in situ 19 | 1,745
Kidney disease 18 | 430
acute quadriplegic myopathy 18 | 1,158
esophageal adenocarcinoma 18 | 737
Alzheimer's disease 17 | 658
Atopic dermatitis 17 | 952
Melanoma 17 | 711
Duchenne muscular dystrophy 16 | 601
Pick disease 16 | 1,894
active ulcerative colitis 16 | 764
gastric carcinoma 16 | 807
group 4 medulloblastoma 16 | 1,855
pituitary cancer 16 | 1,972
adrenocortical carcinoma 15 | 1,428
head and neck cancer and chronic obstructive pulmonary disease 15 | 239
nasopharyngeal carcinoma 15 | 1,058
non primary Sjogren syndrome sicca 15 | 891
primary Sjogren syndrome 15 | 735
Atherosclerosis 14 | 291
Hypertension 14 | 396
pediatric high grade glioma 14 | 1,064
periodontitis 14 | 293
Anemia 13 | 365
Arthritis 13 | 290
Heart disease 13 | 306
spina bifida 13 | 1,074
Down syndrome 12 | 499
Multiple Sclerosis 12 | 540
Skin cancer 12 | 469
Splenomegaly 12 | 190
acute myeloid leukemia 12 | 783
hepatocellular carcinoma 12 | 547
pancreatic carcinoma 12 | 562
Asthma 11 | 385
Schizophrenia 11 | 1,160
active Crohn's disease 11 | 922
Hepatomegaly 10 | 285
Vascular disease 10 | 319
chronic lymphosyte leukemia 10 | 204
Bipolar Disorder 9 | 666
Coronary artery disease 9 | 268
Epilepsy 9 | 792
Hypertensive disease 9 | 292
Lung disease 9 | 142
Neurodegenerative disease 9 | 414
Obesity 9 | 678
gastric cancer 9 | 459
nephrosclerosis 9 | 333
Cerebrovascular disease 8 | 238
Chronic Lymphocytic Leukemia 8 | 262
Intellectual disability 8 | 1,016
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 510
chronic rhinosinusitis 8 | 512

Tissue

Blood and immune system 167 | 16,909
Female tissues 166 | 17,400
Skin and soft tissues 166 | 17,230
Digestive Tract 165 | 17,369
Endocrine System 164 | 18,159
Liver and Pancreas 163 | 16,750
Respiratory system 162 | 16,393
Urinary Tract 161 | 16,678
Male tissues 160 | 17,142
Nervous System 158 | 16,725
Cardiovascular System 152 | 15,192

Target Family

Non-IDG 102 | 12,091
Enzyme 50 | 4,145
Ion Channel 7 | 344
GPCR 5 | 408
Transporter 4 | 473
Transcription Factor 1 | 1,400

Compartment GO Term

Tertiary granule 169 | 169
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Carcinoembryonic antigen-related cell adhesion molecule 8 CEACAM8 Tbio Non-IDG -2.27709 182.9 314
Serpin B12 SERPINB12 Tbio Non-IDG -0.56624 4.27 155
Transient receptor potential cation channel subfamily M member 2 TRPM2 Tchem Ion Channel -1.34318 25.1 209
Leukocyte-associated immunoglobulin-like receptor 1 LAIR1 Tbio Non-IDG -1.74760 64.2 487
C-type lectin domain family 4 member D CLEC4D Tbio Non-IDG -1.43609 25.1 193
Complement receptor type 1 CR1 Tbio Non-IDG -3.36509 2362.6 700
Pentraxin-related protein PTX3 PTX3 Tbio Non-IDG -0.80888 8.68 307
Lysosomal Pro-X carboxypeptidase PRCP Tchem Enzyme -1.87633 85.9 165
Folate receptor gamma FOLR3 Tbio Non-IDG -0.82047 6.26 98
Erythrocyte band 7 integral membrane protein STOM Tbio Non-IDG -2.27504 176.9 163