Development Level

Tbio 14 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
increased circulating chloride... 1 | 41
increased circulating fructosa... 1 | 13
increased circulating sodium l... 1 | 71
increased mean platelet volume 1 | 45
increased red blood cell distr... 1 | 34
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 10 | 11,493
ovarian cancer 10 | 8,520
lung cancer 9 | 4,740
Dyskeratosis congenita 6 | 24
Kidney cancer 6 | 2,613
Abnormal blistering of the skin 5 | 54
Abnormality of female internal genitalia 5 | 13
Abnormality of the fingernails 5 | 51
Abnormality of the pharynx 5 | 19
Anemia 5 | 365
Anorectal Malformations 5 | 8
Aplasia/Hypoplasia of the skin 5 | 16
Blister of skin 5 | 54
Blood Coagulation Disorders 5 | 42
Bone marrow hypocellularity 5 | 20
Cellular immunodeficiency 5 | 17
Coagulation abnormalities 5 | 27
Cognitive delay 5 | 608
Decreased platelet count 5 | 111
Dental caries 5 | 164
Dystrophia unguium 5 | 53
Esophageal Stenosis 5 | 15
Fetal Growth Retardation 5 | 189
Frequent fractures 5 | 53
Gingival Diseases 5 | 19
Global developmental delay 5 | 608
Hemoglobin low 5 | 124
Hemorrhagic Disorders 5 | 30
Hyperhidrosis disorder 5 | 81
Hyperpigmented macules 5 | 42
Hypodontia 5 | 81
Hypoplastic-absent toenails 5 | 11
Increased fracture rate 5 | 53
Increased sweating 5 | 81
Infant, Small for Gestational Age 5 | 176
Intrauterine retardation 5 | 176
Large elongated pulp chamber 5 | 14
Leukokeratosis 5 | 19
Leukoplakia, Oral 5 | 20
Malabsorption 5 | 82
Mental and motor retardation 5 | 608
Neutrophil abnormality 5 | 20
Osteoporosis 5 | 363
Periodontal Diseases 5 | 21
Recurrent respiratory infections 5 | 141
Rotting teeth 5 | 73
Rough bone trabeculation 5 | 11
Short stature 5 | 531
Skin Ulcer 5 | 48
Skin bulla 5 | 54
Sparse hair 5 | 59
Sweating 5 | 81
Taurodontism 5 | 14
Telangiectasia of the skin 5 | 39
Thin, sparse hair 5 | 59
Thrombocytopenia 5 | 197
Tracheoesophageal Fistula 5 | 36
Urethral Stricture 5 | 18
Varying degree of multiple fractures 5 | 53
hypopigmented skin patch 5 | 59
medulloblastoma, large-cell 5 | 6,241
periodontitis 5 | 293
Dull intelligence 4 | 645
Intellectual disability 4 | 1,016
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Multiple myeloma 4 | 1,332
Poor school performance 4 | 645
Pulmonary Fibrosis 4 | 106
Small head 4 | 374
Sparse scalp hair 4 | 42
group 3 medulloblastoma 4 | 4,104
psoriasis 4 | 6,694
Aplastic Anemia 3 | 21
Autosomal recessive predisposition 3 | 1,442
Breast cancer 3 | 3,578
Cancer 3 | 2,499
Dyskeratosis congenita autosomal recessive 1 3 | 3
Excessive tearing 3 | 12
Highly variable clinical phenotype 3 | 150
Highly variable phenotype and severity 3 | 150
Highly variable phenotype, even within families 3 | 150
Hyperpigmentation 3 | 37
Idiopathic pulmonary fibrosis 3 | 23
Liver Cirrhosis 3 | 181
Nail dysplasia 3 | 52
Pancytopenia 3 | 45
Phenotypic variability 3 | 150
Pterygium of nail 3 | 3
Sparse eyelashes 3 | 31
Waldenstrons macroglobulinemia 3 | 765
non primary Sjogren syndrome sicca 3 | 891
osteosarcoma 3 | 7,950
Coronary artery disease 2 | 268
Failure to gain weight 2 | 365
Lung Neoplasms 2 | 232
Pediatric failure to thrive 2 | 365
Reperfusion Injury 2 | 86
cystic fibrosis 2 | 1,696

Tissue

Blood and immune system 17 | 16,909
Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678
Cardiovascular System 15 | 15,192
Nervous System 14 | 16,725

Target Family

Enzyme 9 | 4,145
Non-IDG 6 | 12,091
GPCR 1 | 408
Transcription Factor 1 | 1,400

Compartment GO Term

Telomerase holoenzyme complex 17 | 17
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Telomerase protein component 1 TEP1 Tbio Enzyme -1.74492 50.6 71
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2 SOHLH2 Tbio Transcription Factor -1.26578 21.4 126
Telomerase-binding protein EST1A SMG6 Tbio Enzyme -1.48788 32.6 37
H/ACA ribonucleoprotein complex subunit 2 NHP2 Tbio Non-IDG -1.51951 28.7 54
Estrogen sulfotransferase SULT1E1 Tchem Enzyme -2.97379 932.9 156
Protein SMG5 SMG5 Tbio Non-IDG -1.02024 9.67 88
H/ACA ribonucleoprotein complex subunit 3 NOP10 Tbio Non-IDG -1.36742 17.7 34
Ribonuclease P protein subunit p20 POP7 Tbio Enzyme -0.86962 7.33 47
Telomerase reverse transcriptase TERT Tchem Enzyme -3.56910 3506.4 643
ATP-dependent RNA helicase DHX36 DHX36 Tbio Enzyme -1.55120 37.4 112