Development Level

Tbio 22 | 11,651
Tdark 2 | 6,593
Tclin 1 | 612

IMPC Phenotype

increased circulating sodium l... 2 | 71
increased or absent threshold ... 2 | 101
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal locomotor activation 1 | 16
absent pinna reflex 1 | 23
decreased body weight 1 | 161
decreased circulating free fat... 1 | 31
decreased prepulse inhibition 1 | 82
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased circulating triglyce... 1 | 42
increased lean body mass 1 | 172
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
persistence of hyaloid vascula... 1 | 33
stereotypic behavior 1 | 3
trunk curl 1 | 16

Disease

Nonsyndromic deafness 23 | 142
Carcinoma 21 | 11,493
Sensorineural hearing loss 18 | 106
Hodgkin's lymphoma, nodular sclerosis 10 | 22
Autosomal recessive predisposition 8 | 1,442
Sensorineural Hearing Loss (disorder) 8 | 284
medulloblastoma, large-cell 8 | 6,241
psoriasis 8 | 6,694
Breast cancer 7 | 3,578
Kidney cancer 7 | 2,613
osteosarcoma 7 | 7,950
Astrocytoma, Pilocytic 6 | 3,081
Deafness 6 | 198
group 3 medulloblastoma 6 | 4,104
lung adenocarcinoma 6 | 2,716
lung cancer 6 | 4,740
pituitary cancer 6 | 1,972
Usher syndrome 5 | 32
adult high grade glioma 5 | 3,801
atypical teratoid / rhabdoid tumor 5 | 5,112
ependymoma 5 | 4,679
non-small cell lung cancer 5 | 2,890
ovarian cancer 5 | 8,520
pancreatic cancer 5 | 2,398
Melanoma 4 | 711
Retinitis Pigmentosa 4 | 226
glioblastoma 4 | 5,792
hearing impairment 4 | 199
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
oligodendroglioma 4 | 2,850
primitive neuroectodermal tumor 4 | 3,035
Atopic dermatitis 3 | 952
Blindness 3 | 88
Cataract 3 | 297
Cognitive delay 3 | 608
Congenital deafness 3 | 185
Dull intelligence 3 | 645
Enlarged vestibular aqueduct 3 | 10
Global developmental delay 3 | 608
Hearing Loss, Partial 3 | 185
Hearing Loss, Sensorineural 3 | 11
Intellectual disability 3 | 1,016
Liver cancer 3 | 604
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Myopia 3 | 176
Neuropathy 3 | 261
Pendred Syndrome 3 | 22
Poor school performance 3 | 645
Short stature 3 | 531
Skin cancer 3 | 469
Usher Syndrome, Type 1 3 | 7
Usher Syndrome, Type I 3 | 6
astrocytic glioma 3 | 2,597
cystic fibrosis 3 | 1,696
group 4 medulloblastoma 3 | 1,855
malignant mesothelioma 3 | 3,232
Alzheimer's disease 2 | 658
Arthralgia 2 | 90
Asthma 2 | 385
Cancer 2 | 2,499
Degenerative polyarthritis 2 | 115
Diastrophic dysplasia 2 | 21
Dizziness 2 | 26
Endometrial cancer 2 | 311
Epilepsy 2 | 792
Feeding difficulties in infancy 2 | 175
Glaucoma 2 | 239
Hypoplastic mandible condyle 2 | 275
Hypothyroidism 2 | 122
Hypotrophic malar bone 2 | 129
Lens Opacities 2 | 231
Malar flattening 2 | 129
Male infertility 2 | 206
Micromelia 2 | 58
Osteoarthritis 2 | 184
Progressive disorder 2 | 142
Short metacarpal 2 | 43
Tinnitus 2 | 19
USHER SYNDROME, TYPE ID 2 | 2
Uranostaphyloschisis 2 | 167
Usher syndrome, type 1D 2 | 2
Vertigo 2 | 29
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
facioscapulohumeral dystrophy 2 | 288
interstitial cystitis 2 | 2,312
lung carcinoma 2 | 2,843
nasopharyngeal carcinoma 2 | 1,058
pediatric high grade glioma 2 | 1,064
primary pancreatic ductal adenocarcinoma 2 | 1,109
spina bifida 2 | 1,074
subependymal giant cell astrocytoma 2 | 2,287
substance-related disorder 2 | 162
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819

Tissue

Endocrine System 23 | 18,159
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Nervous System 22 | 16,725
Skin and soft tissues 22 | 17,230
Blood and immune system 21 | 16,909
Digestive Tract 21 | 17,369
Female tissues 21 | 17,400
Respiratory system 19 | 16,393
Urinary Tract 17 | 16,678
Cardiovascular System 16 | 15,192

Target Family

Non-IDG 20 | 12,091
Enzyme 2 | 4,145
Ion Channel 2 | 344
Transporter 1 | 473

Compartment GO Term

Tectum 25 | 25
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Potassium voltage-gated channel subfamily KQT member 4 KCNQ4 Tclin Ion Channel -2.04030 109.2 258
Gap junction beta-2 protein GJB2 Tbio Non-IDG -3.17642 1514.7 242
Transmembrane protease serine 3 TMPRSS3 Tbio Enzyme -1.43087 28.0 227
Transmembrane protease serine 4 TMPRSS4 Tbio Enzyme -1.72654 55.1 216
Cadherin-23 CDH23 Tbio Non-IDG -2.01011 103.6 189
Cochlin COCH Tbio Non-IDG -2.50102 315.5 168
Collagen alpha-2(XI) chain COL11A2 Tbio Non-IDG -1.89476 73.6 143
Unconventional myosin-VIIa MYO7A Tbio Non-IDG -2.14713 133.5 129
Wolframin WFS1 Tbio Non-IDG -2.40006 260.2 118
Collagen alpha-3(IX) chain COL9A3 Tbio Non-IDG -1.35534 21.6 115