Development Level

Tbio 32 | 10,625
Tchem 20 | 1,890
Tclin 2 | 602
Tdark 2 | 7,003

IMPC Phenotype

preweaning lethality, complete... 6 | 633
embryonic lethality prior to t... 3 | 187
abnormal behavior 1 | 226
abnormal embryo size 1 | 112
abnormal eye posterior chamber... 1 | 3
corneal opacity 1 | 25
decreased blood urea nitrogen ... 1 | 31
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased circulating LDL chol... 1 | 37
decreased circulating aspartat... 1 | 27
decreased circulating creatini... 1 | 31
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
decreased total retina thickne... 1 | 20
dilated heart left ventricle 1 | 10
embryonic lethality prior to o... 1 | 148
enlarged adrenal glands 1 | 3
enlarged kidney 1 | 7
enlarged uterus 1 | 3
female infertility 1 | 34
hydrometra 1 | 13
impaired glucose tolerance 1 | 52
improved glucose tolerance 1 | 56
increased bone mineral content 1 | 92
increased cardiac stroke volum... 1 | 1
increased circulating LDL chol... 1 | 15
increased erythrocyte cell num... 1 | 26
increased fasted circulating g... 1 | 68
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
irregularly shaped pupil 1 | 7
male infertility 1 | 62
polycystic kidney 1 | 9
prenatal lethality prior to he... 1 | 64

Disease

ovarian cancer 34 | 8,491
Cancer 32 | 2,346
osteosarcoma 24 | 7,933
medulloblastoma, large-cell 20 | 6,234
psoriasis 20 | 6,685
Carcinoma 15 | 2,147
atypical teratoid / rhabdoid tumor 15 | 4,369
glioblastoma 15 | 5,572
lung cancer 15 | 4,473
Breast cancer 14 | 3,098
diabetes mellitus 13 | 1,663
malignant mesothelioma 13 | 3,163
Obesity 12 | 616
group 3 medulloblastoma 11 | 2,254
invasive ductal carcinoma 11 | 2,950
adult high grade glioma 10 | 2,148
ependymoma 10 | 2,514
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,289
ductal carcinoma in situ 9 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,988
oligodendroglioma 9 | 2,849
Alzheimer's disease 8 | 644
Hyperglycemia 8 | 120
Pick disease 8 | 1,893
Renal Cell Carcinoma 8 | 199
Vascular disease 8 | 281
acute quadriplegic myopathy 8 | 1,157
cystic fibrosis 8 | 1,670
lung adenocarcinoma 8 | 2,714
non-small cell lung cancer 8 | 2,798
Epilepsy 7 | 346
Metabolic syndrome X 7 | 155
adrenocortical carcinoma 7 | 1,427
astrocytic glioma 7 | 2,241
colon cancer 7 | 1,475
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,795
pediatric high grade glioma 7 | 2,712
subependymal giant cell astrocytoma 7 | 2,287
tuberculosis 7 | 1,563
Hyperinsulinism 6 | 63
Hypertensive disease 6 | 193
Intellectual disability 6 | 573
Liver carcinoma 6 | 217
Polycystic Ovary Syndrome 6 | 334
astrocytoma 6 | 1,493
breast carcinoma 6 | 1,614
group 4 medulloblastoma 6 | 1,875
pilocytic astrocytoma 6 | 3,086
pituitary cancer 6 | 1,972
Angiomyolipoma 5 | 17
Autistic Disorder 5 | 320
Fatty liver disease 5 | 86
Heart disease 5 | 279
Kidney angiomyolipoma 5 | 8
Kidney disease 5 | 397
Lymphangioleiomyomatosis 5 | 17
Mammary Neoplasms 5 | 410
Neoplastic Syndromes, Hereditary 5 | 48
Parkinson's disease 5 | 364
Prostatic Neoplasms 5 | 471
Rheumatoid Arthritis 5 | 1,170
interstitial cystitis 5 | 2,299
juvenile dermatomyositis 5 | 1,189
lung carcinoma 5 | 2,844
Adenoma 4 | 165
Atopic dermatitis 4 | 944
Hypertension 4 | 293
Insulin Resistance 4 | 50
Leukemia, Myelocytic, Acute 4 | 113
Lipid metabolism disorder 4 | 102
Liver disease 4 | 219
Lung Neoplasms 4 | 171
Muscular atrophy 4 | 67
Myopathy 4 | 128
Neurodegenerative disease 4 | 383
Osteoporosis 4 | 259
Schizophrenia 4 | 503
Squamous cell carcinoma 4 | 96
pancreatic cancer 4 | 2,300
primary pancreatic ductal adenocarcinoma 4 | 1,271
primitive neuroectodermal tumor 4 | 3,031
tuberculosis and treatment for 3 months 4 | 327
Amyotrophic Lateral Sclerosis 3 | 432
Atherosclerosis 3 | 275
Coronary artery disease 3 | 240
Disease Progression 3 | 125
Endometriosis 3 | 535
Lung disease 3 | 136
Multiple myeloma 3 | 1,327
Nerve Degeneration 3 | 73
Pancreatic Neoplasm 3 | 79
Reperfusion Injury 3 | 84
Toxic encephalopathy 3 | 131
aldosterone-producing adenoma 3 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
medulloblastoma 3 | 1,524
progressive supranuclear palsy 3 | 674
sonic hedgehog group medulloblastoma 3 | 1,482
ulcerative colitis 3 | 2,087

Tissue

Blood and immune system 54 | 17,994
Cardiovascular System 54 | 17,957
Digestive Tract 54 | 18,472
Endocrine System 54 | 18,511
Female tissues 54 | 18,646
Liver and Pancreas 54 | 18,135
Male tissues 54 | 17,968
Nervous System 54 | 18,560
Skin and soft tissues 54 | 18,114
Urinary Tract 54 | 18,443
Respiratory system 53 | 17,483

Target Family

Non-IDG 32 | 11,969
Kinase 11 | 634
Enzyme 6 | 4,146
Transporter 4 | 473
Transcription Factor 3 | 1,400

Compartment GO Term

TORC1 complex 56 | 56
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
TELO2-interacting protein 1 homolog TTI1 Tbio Non-IDG -0.83395 6.09 63
Large neutral amino acids transporter small subunit 1 SLC7A5 Tbio Transporter -1.84839 135.6 220
Forkhead box protein O1 FOXO1 Tbio Transcription Factor -2.99634 1000.8 1343
Target of rapamycin complex subunit LST8 MLST8 Tbio Non-IDG -2.61267 401.4 319
Ras-related GTP-binding protein A RRAGA Tbio Non-IDG -1.53771 36.0 91
Ras-related GTP-binding protein D RRAGD Tbio Non-IDG -0.79184 4.99 76
Insulin receptor substrate 1 IRS1 Tbio Non-IDG -3.16181 1410.3 1769
Putative L-type amino acid transporter 1-like protein MLAS SLC7A5P1 Tdark Transporter -1.84839 135.6 0
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN PTEN Tchem Enzyme -3.66888 4696.1 874
Serine/threonine-protein kinase ULK1 ULK1 Tchem Kinase -2.48300 293.5 568