Development Level

Tbio 62 | 11,651
Tchem 38 | 1,388
Tclin 16 | 612
Tdark 4 | 6,593

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 14 | 979
preweaning lethality, incomple... 7 | 499
embryonic lethality prior to t... 4 | 278
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
increased mean corpuscular hem... 3 | 96
increased total body fat amoun... 3 | 134
abnormal bone mineralization 2 | 38
abnormal femur morphology 2 | 14
decreased body weight 2 | 161
decreased circulating LDL chol... 2 | 38
decreased circulating alanine ... 2 | 47
decreased circulating aspartat... 2 | 34
decreased circulating creatini... 2 | 39
improved glucose tolerance 2 | 79
increased circulating LDL chol... 2 | 13
increased lean body mass 2 | 172
increased startle reflex 2 | 112
male infertility 2 | 123
abnormal forebrain development 1 | 20
abnormal glucose homeostasis 1 | 4
abnormal head morphology 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal hindbrain development 1 | 16
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal startle reflex 1 | 15
abnormal vertebrae morphology 1 | 18
anophthalmia 1 | 33
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
dilated heart left ventricle 1 | 11
edema 1 | 59
embryonic lethality prior to o... 1 | 239
female infertility 1 | 60
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased aggression 1 | 4
increased body length 1 | 32
increased bone mineral density 1 | 72
increased cardiac stroke volum... 1 | 1
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased grip strength 1 | 41
increased hemoglobin content 1 | 45
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
mammalian phenotype 1 | 17
microphthalmia 1 | 26
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
thrombocytopenia 1 | 56
thrombocytosis 1 | 27

Disease

Cancer 93 | 2,499
Carcinoma 87 | 11,493
ovarian cancer 81 | 8,520
osteosarcoma 65 | 7,950
psoriasis 53 | 6,694
lung cancer 49 | 4,740
glioblastoma 48 | 5,792
medulloblastoma, large-cell 46 | 6,241
diabetes mellitus 42 | 1,728
atypical teratoid / rhabdoid tumor 41 | 5,112
Breast cancer 39 | 3,578
ependymoma 38 | 4,679
Vascular disease 33 | 319
Schizophrenia 32 | 1,160
Breast Neoplasms 31 | 445
Kidney cancer 31 | 2,613
Mammary Neoplasms 31 | 425
intraductal papillary-mucinous neoplasm (IPMN) 30 | 3,291
group 3 medulloblastoma 29 | 4,104
invasive ductal carcinoma 29 | 2,951
malignant mesothelioma 29 | 3,232
Obesity 28 | 678
oligodendroglioma 27 | 2,850
Lung Neoplasms 25 | 232
adult high grade glioma 25 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,989
non-small cell lung cancer 25 | 2,890
Carcinoma, Hepatocellular 23 | 228
Liver carcinoma 23 | 240
Prostatic Neoplasms 23 | 495
Stomach Neoplasms 23 | 300
breast carcinoma 22 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 22 | 2,955
subependymal giant cell astrocytoma 22 | 2,287
Alzheimer's disease 21 | 658
astrocytic glioma 21 | 2,597
lung adenocarcinoma 21 | 2,716
tuberculosis 21 | 2,010
Astrocytoma, Pilocytic 20 | 3,081
Carcinoma, Squamous Cell 20 | 110
Heart disease 20 | 306
Kidney disease 20 | 430
Neoplasm Metastasis 20 | 168
Renal Cell Carcinoma 20 | 214
Squamous cell carcinoma 20 | 129
acute quadriplegic myopathy 20 | 1,158
pancreatic cancer 20 | 2,398
primitive neuroectodermal tumor 20 | 3,035
ulcerative colitis 20 | 1,819
Intellectual disability 19 | 1,016
astrocytoma 19 | 1,146
pituitary cancer 19 | 1,972
Bipolar Disorder 18 | 666
Epilepsy 18 | 792
Hyperglycemia 18 | 137
Neurodegenerative disease 18 | 414
Pick disease 18 | 1,894
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,962
Adenocarcinoma 17 | 122
Adenoma 17 | 167
Autosomal recessive predisposition 17 | 1,442
Hypertension 17 | 396
Multiple myeloma 17 | 1,332
Seizures 17 | 596
ductal carcinoma in situ 17 | 1,745
Ovarian Neoplasms 16 | 102
Toxic encephalopathy 16 | 141
group 4 medulloblastoma 16 | 1,855
interstitial cystitis 16 | 2,312
Anemia 15 | 365
Arthritis 15 | 290
Dull intelligence 15 | 645
Liver disease 15 | 237
Low intelligence 15 | 645
Mental Retardation 15 | 645
Mental deficiency 15 | 645
Poor school performance 15 | 645
Rheumatoid arthritis 15 | 1,191
cystic fibrosis 15 | 1,696
lung carcinoma 15 | 2,843
Depressive disorder 14 | 409
Liver cancer 14 | 604
Major Depressive Disorder 14 | 301
Neoplasm Invasiveness 14 | 161
Polycystic ovary syndrome 14 | 360
adrenocortical carcinoma 14 | 1,428
Atherosclerosis 13 | 291
Cell Transformation, Neoplastic 13 | 97
Cognitive delay 13 | 608
Colonic Neoplasms 13 | 142
Endometrial cancer 13 | 311
Global developmental delay 13 | 608
Liver Neoplasms, Experimental 13 | 59
Melanoma 13 | 711
Mental and motor retardation 13 | 608
Pancreatic Neoplasms 13 | 85
Unipolar Depression 13 | 250
juvenile dermatomyositis 13 | 1,187
ovarian neoplasm 13 | 99
Immune system cancer 12 | 140

Tissue

Blood and immune system 114 | 16,909
Cardiovascular System 114 | 15,192
Digestive Tract 114 | 17,369
Endocrine System 114 | 18,159
Female tissues 114 | 17,400
Liver and Pancreas 114 | 16,750
Nervous System 114 | 16,725
Respiratory system 114 | 16,393
Skin and soft tissues 114 | 17,230
Urinary Tract 114 | 16,678
Male tissues 113 | 17,142

Target Family

Non-IDG 59 | 12,091
Kinase 33 | 634
Transcription Factor 11 | 1,400
Enzyme 10 | 4,145
Transporter 5 | 473
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

Compartment GO Term

TOR complex 120 | 120
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
MAP kinase-interacting serine/threonine-protein kinase 1 MKNK1 Tchem Kinase -1.71576 46.7 408
Claudin-12 CLDN12 Tbio Non-IDG -1.03235 8.71 137
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075
Estrogen receptor ESR1 Tclin Nuclear Receptor -4.00480 8421.6 2610
Calcineurin-binding protein cabin-1 CABIN1 Tbio Non-IDG -3.37173 2194.3 57
Sequestosome-1 SQSTM1 Tbio Non-IDG -2.78728 635.1 766
Programmed cell death 1 ligand 1 CD274 Tclin Non-IDG -3.53386 3285.3 993
Signal transducer and activator of transcription 3 STAT3 Tchem Transcription Factor -3.81500 6459.7 1749
Ubiquitin-like protein ATG12 ATG12 Tbio Non-IDG -2.17958 122.1 528
Target of rapamycin complex subunit LST8 MLST8 Tbio Non-IDG -2.64631 429.3 360