Development Level

Tbio 31 | 11,651
Tdark 10 | 6,593
Tchem 3 | 1,388

IMPC Phenotype

male infertility 7 | 123
female infertility 5 | 60
decreased bone mineral content 3 | 151
abnormal behavioral response t... 2 | 66
decreased bone mineral density 2 | 126
increased leukocyte cell numbe... 2 | 47
preweaning lethality, complete... 2 | 979
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
cardiovascular system phenotyp... 1 | 36
decreased body weight 1 | 161
decreased circulating iron lev... 1 | 32
decreased heart rate variabili... 1 | 13
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased body temperature 1 | 9
increased circulating HDL chol... 1 | 80
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased mean corpuscular vol... 1 | 92
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
shortened RR interval 1 | 17
shortened ST segment 1 | 10
small testis 1 | 58

Disease

Carcinoma 29 | 11,493
glioblastoma 16 | 5,792
ovarian cancer 16 | 8,520
osteosarcoma 15 | 7,950
group 3 medulloblastoma 14 | 4,104
medulloblastoma, large-cell 13 | 6,241
psoriasis 13 | 6,694
Male infertility 12 | 206
lung cancer 11 | 4,740
non-small cell lung cancer 11 | 2,890
Breast cancer 10 | 3,578
Kidney cancer 10 | 2,613
atypical teratoid / rhabdoid tumor 10 | 5,112
primitive neuroectodermal tumor 10 | 3,035
Infertility 9 | 188
lung adenocarcinoma 9 | 2,716
Cancer 8 | 2,499
adult high grade glioma 8 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
malignant mesothelioma 8 | 3,232
ependymoma 7 | 4,679
invasive ductal carcinoma 7 | 2,951
Astrocytoma, Pilocytic 6 | 3,081
Premature ovarian failure 6 | 65
Short stature 6 | 531
Small head 6 | 374
ductal carcinoma in situ 6 | 1,745
Anxiety 5 | 136
Anxiety disease 5 | 113
Attention deficit hyperactivity disorder 5 | 278
Autosomal recessive predisposition 5 | 1,442
Azoospermia 5 | 110
Cognitive delay 5 | 608
Global developmental delay 5 | 608
Intellectual disability 5 | 1,016
Mental and motor retardation 5 | 608
Muscle Hypertonia 5 | 88
colon cancer 5 | 1,478
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
oligodendroglioma 5 | 2,850
Bilateral fifth finger clinodactyly 4 | 110
Chromosome Breakage 4 | 36
Cryptorchidism 4 | 296
Curvature of little finger 4 | 110
Delayed bone age 4 | 136
Dull intelligence 4 | 645
Endometrial cancer 4 | 311
Fetal Growth Retardation 4 | 189
Infant, Small for Gestational Age 4 | 176
Intrauterine retardation 4 | 176
Low intelligence 4 | 645
Lynch syndrome 4 | 35
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Poor school performance 4 | 645
Premature Menopause 4 | 31
Prostate cancer 4 | 175
Prostatic Neoplasms 4 | 495
Short nose 4 | 132
Small nose 4 | 132
breast carcinoma 4 | 1,638
cystic fibrosis 4 | 1,696
pituitary cancer 4 | 1,972
Absent auditory canals 3 | 23
Absent external auditory canals 3 | 23
Anemia 3 | 365
Anteverted nostril 3 | 191
Atresia of the external auditory canal 3 | 23
Atretic auditory canal 3 | 23
Bilateral single transverse palmar creases 3 | 34
Blepharoptosis 3 | 231
Brachycephaly 3 | 88
Broad cranium shape 3 | 88
Byzanthine arch palate 3 | 194
Concave bridge of nose 3 | 195
Constipation 3 | 181
Depressed nasal bridge 3 | 195
Depressed nasal root/bridge 3 | 195
Failure to gain weight 3 | 365
Gastroesophageal reflux disease 3 | 110
Heartburn 3 | 78
Leukemia, Myeloid 3 | 18
Liver cancer 3 | 604
Long philtrum 3 | 137
Micromelia 3 | 58
Myeloid Leukemia 3 | 19
Myopia 3 | 176
Pancreatic Neoplasm 3 | 85
Pancreatic Neoplasms 3 | 85
Pediatric failure to thrive 3 | 365
Premature Birth 3 | 77
Premature birth of newborn 3 | 67
Severe mental retardation (I.Q. 20-34) 3 | 99
Speech Disorders 3 | 58
Syndactyly of the toes 3 | 45
Thin lips 3 | 49
Wide skull shape 3 | 88
atypical teratoid/rhabdoid tumor 3 | 357
medulloblastoma 3 | 720
posterior fossa group A ependymoma 3 | 468

Tissue

Endocrine System 44 | 18,159
Female tissues 41 | 17,400
Digestive Tract 40 | 17,369
Skin and soft tissues 40 | 17,230
Blood and immune system 38 | 16,909
Male tissues 37 | 17,142
Nervous System 37 | 16,725
Liver and Pancreas 36 | 16,750
Urinary Tract 36 | 16,678
Respiratory system 35 | 16,393
Cardiovascular System 30 | 15,192

Target Family

Non-IDG 35 | 12,091
Enzyme 7 | 4,145
Transporter 2 | 473

Compartment GO Term

Synaptonemal complex 44 | 44
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
MutS protein homolog 5 MSH5 Tbio Non-IDG -1.75314 0.00000 142
Zinc transporter ZIP1 SLC39A1 Tbio Transporter -1.89903 75.9 61
Meiotic nuclear division protein 1 homolog MND1 Tbio Non-IDG -1.39230 25.7 115
Testis-expressed protein 12 TEX12 Tdark Non-IDG -0.49336 2.83 83
SUMO-conjugating enzyme UBC9 UBE2I Tbio Non-IDG -2.45979 267.1 368
Breast cancer type 1 susceptibility protein BRCA1 Tchem Non-IDG -3.76784 6081.3 1542
DNA mismatch repair protein Mlh3 MLH3 Tbio Non-IDG -1.78372 64.5 112
DNA mismatch repair protein Mlh1 MLH1 Tbio Non-IDG -3.34283 2352.6 495
Synaptonemal complex protein 3 SYCP3 Tbio Non-IDG -2.20845 154.4 255
Protein FAM9C FAM9C Tdark Non-IDG 0.15 0.89 8