Development Level

Tbio 146 | 11,445
Tclin 68 | 613
Tchem 28 | 1,598
Tdark 24 | 6,588

Collection

Ion Channel: IDG Consortium (T... 15 | 99
GPCR: IDG Consortium (Complete... 2 | 25

IMPC Phenotype

decreased total body fat amoun... 12 | 207
preweaning lethality, complete... 7 | 979
abnormal behavior 6 | 298
decreased grip strength 6 | 116
increased circulating chloride... 6 | 41
hyperactivity 5 | 148
increased lean body mass 5 | 172
increased mean corpuscular vol... 5 | 92
increased or absent threshold ... 5 | 101
increased total body fat amoun... 5 | 134
preweaning lethality, incomple... 5 | 499
tremors 5 | 39
abnormal bone structure 4 | 187
abnormal locomotor behavior 4 | 24
decreased body weight 4 | 161
decreased circulating HDL chol... 4 | 68
decreased lymphocyte cell numb... 4 | 83
embryonic lethality prior to t... 4 | 278
impaired glucose tolerance 4 | 75
increased heart weight 4 | 62
decreased circulating choleste... 3 | 93
decreased fasted circulating g... 3 | 65
embryonic lethality prior to o... 3 | 239
hypoactivity 3 | 132
increased bone mineral content 3 | 108
increased circulating sodium l... 3 | 71
abnormal cornea morphology 2 | 31
abnormal epididymis morphology 2 | 42
abnormal gait 2 | 69
abnormal joint morphology 2 | 23
abnormal retina morphology 2 | 71
brachydactyly 2 | 19
decreased bone mineral content 2 | 151
decreased circulating alkaline... 2 | 46
decreased exploration in new e... 2 | 11
decreased heart weight 2 | 27
decreased lean body mass 2 | 135
decreased mean corpuscular vol... 2 | 79
decreased neutrophil cell numb... 2 | 42
decreased pulmonary respirator... 2 | 5
decreased startle reflex 2 | 75
decreased vertical activity 2 | 208
enlarged heart 2 | 210
enlarged stomach 2 | 2
increased circulating alkaline... 2 | 122
increased circulating amylase ... 2 | 25
increased fasted circulating g... 2 | 76
increased neutrophil cell numb... 2 | 46
increased red blood cell distr... 2 | 34
increased startle reflex 2 | 112
persistence of hyaloid vascula... 2 | 33
short tibia 2 | 97
small thymus 2 | 16
syndactyly 2 | 23
abnormal behavioral response t... 1 | 66
abnormal brain morphology 1 | 13
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal ear morphology 1 | 9
abnormal eye morphology 1 | 68
abnormal lens morphology 1 | 81
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
absent startle reflex 1 | 24
cataract 1 | 92
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased cardiac muscle contr... 1 | 11
decreased circulating LDL chol... 1 | 38
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased food intake 1 | 13
decreased heart left ventricle... 1 | 28
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
edema 1 | 59
hydroencephaly 1 | 14
impaired pupillary reflex 1 | 26
increased cardiac muscle contr... 1 | 8
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased circulating triglyce... 1 | 42
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
limb grasping 1 | 41
prenatal lethality prior to he... 1 | 87
small superior vagus ganglion 1 | 74
small testis 1 | 58
thin ventricular wall 1 | 24

Disease

Carcinoma 216 | 11,493
medulloblastoma, large-cell 171 | 6,241
atypical teratoid / rhabdoid tumor 155 | 5,112
glioblastoma 152 | 5,792
ependymoma 141 | 4,679
adult high grade glioma 131 | 3,801
Astrocytoma, Pilocytic 106 | 3,081
oligodendroglioma 106 | 2,850
psoriasis 104 | 6,694
group 3 medulloblastoma 102 | 4,104
ovarian cancer 102 | 8,520
primitive neuroectodermal tumor 102 | 3,035
astrocytic glioma 100 | 2,597
osteosarcoma 100 | 7,950
Schizophrenia 99 | 1,160
Kidney cancer 82 | 2,613
lung cancer 80 | 4,740
subependymal giant cell astrocytoma 70 | 2,287
lung carcinoma 69 | 2,843
Epilepsy 63 | 792
Pick disease 62 | 1,894
Bipolar Disorder 57 | 666
Breast cancer 55 | 3,578
pituitary cancer 51 | 1,972
Intellectual disability 48 | 1,016
Autistic Disorder 45 | 364
malignant mesothelioma 45 | 3,232
Alcoholic Intoxication, Chronic 40 | 289
General anesthesia 40 | 53
intraductal papillary-mucinous carcinoma (IPMC) 38 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 38 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 37 | 2,955
group 4 medulloblastoma 36 | 1,855
invasive ductal carcinoma 35 | 2,951
lung adenocarcinoma 35 | 2,716
non-small cell lung cancer 34 | 2,890
Autosomal recessive predisposition 33 | 1,442
Parkinson's disease 33 | 392
Depressive disorder 32 | 409
Mental Depression 31 | 333
Liver cancer 30 | 604
colon cancer 29 | 1,478
interstitial cystitis 29 | 2,312
Alzheimer's disease 28 | 658
Seizures 26 | 596
cystic fibrosis 26 | 1,696
Alcohol dependence 25 | 107
Major Depressive Disorder 25 | 301
Muscle hypotonia 25 | 571
Tonic-clonic epilepsy 25 | 47
ductal carcinoma in situ 24 | 1,745
tuberculosis 24 | 2,010
Dull intelligence 23 | 645
Low intelligence 23 | 645
Melanoma 23 | 711
Mental Retardation 23 | 645
Mental deficiency 23 | 645
Poor school performance 23 | 645
breast carcinoma 23 | 1,638
Amyotrophic lateral sclerosis 22 | 451
medulloblastoma 22 | 720
pancreatic cancer 22 | 2,398
Mood Disorders 21 | 184
Toxic encephalopathy 21 | 141
Anxiety 20 | 136
Local anesthesia 20 | 40
Skin cancer 20 | 469
Unipolar Depression 19 | 250
Cancer 18 | 2,499
Cognitive delay 18 | 608
Global developmental delay 18 | 608
Mental and motor retardation 18 | 608
Nicotine dependence 18 | 54
ulcerative colitis 18 | 1,819
Cocaine-Related Disorders 17 | 92
Neurodegenerative disease 17 | 414
astrocytoma 17 | 1,146
pediatric high grade glioma 17 | 1,064
Autism spectrum disorder 16 | 101
Insomnia 16 | 20
Tetanus 16 | 68
acute quadriplegic myopathy 16 | 1,158
adrenocortical carcinoma 16 | 1,428
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,962
Alcoholism 15 | 45
Lennox-Gastaut syndrome 15 | 34
Neuropathy 15 | 261
Attention deficit hyperactivity disorder 14 | 278
Endometrial cancer 14 | 311
Infantile onset 14 | 238
Simple partial seizure 14 | 26
diabetes mellitus 14 | 1,728
juvenile dermatomyositis 14 | 1,187
spina bifida 14 | 1,074
Acquired scoliosis 13 | 281
Curvature of spine 13 | 282
Down syndrome 13 | 499
Dysarthria 13 | 192
Rheumatoid arthritis 13 | 1,191
Status Epilepticus 13 | 98

Tissue

Endocrine System 261 | 18,159
Nervous System 255 | 16,725
Digestive Tract 249 | 17,369
Female tissues 248 | 17,400
Skin and soft tissues 248 | 17,230
Male tissues 242 | 17,142
Urinary Tract 236 | 16,678
Liver and Pancreas 234 | 16,750
Blood and immune system 233 | 16,909
Respiratory system 221 | 16,393
Cardiovascular System 196 | 15,192

Target Family

Non-IDG 138 | 12,091
Ion Channel 69 | 344
Enzyme 32 | 4,145
GPCR 19 | 408
Kinase 7 | 634
Epigenetic 1 | 242

Compartment GO Term

Synaptic membrane 266 | 266
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
43 kDa receptor-associated protein of the synapse RAPSN Tbio Non-IDG -2.09902 132.1 134
E3 ubiquitin-protein ligase Praja-2 PJA2 Tbio Enzyme -0.64427 3.70 175
Signal-induced proliferation-associated 1-like protein 1 SIPA1L1 Tbio Non-IDG -0.56258 5.05 40
Delphilin GRID2IP Tdark Non-IDG -0.73531 6.97 47
Ras/Rap GTPase-activating protein SynGAP SYNGAP1 Tbio Enzyme -1.91757 81.2 178
Brain and acute leukemia cytoplasmic protein BAALC Tbio Non-IDG -1.65293 47.9 117
Potassium voltage-gated channel subfamily A member 2 KCNA2 Tclin Ion Channel -2.55550 343.3 205
Metabotropic glutamate receptor 7 GRM7 Tchem GPCR -2.25415 190.8 304