Development Level

Tbio 416 | 11,445
Tclin 102 | 613
Tchem 89 | 1,598
Tdark 55 | 6,588

Collection

Ion Channel: IDG Consortium (T... 16 | 99
GPCR: IDG Consortium (Complete... 2 | 25
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 40 | 979
preweaning lethality, incomple... 29 | 499
abnormal behavior 27 | 298
decreased total body fat amoun... 21 | 207
decreased grip strength 14 | 116
embryonic lethality prior to t... 14 | 278
hyperactivity 14 | 148
increased total body fat amoun... 14 | 134
decreased vertical activity 12 | 208
increased lean body mass 12 | 172
increased circulating sodium l... 11 | 71
abnormal bone structure 10 | 187
increased or absent threshold ... 10 | 101
decreased body weight 9 | 161
decreased bone mineral content 9 | 151
decreased fasted circulating g... 9 | 65
embryonic lethality prior to o... 9 | 239
increased bone mineral content 9 | 108
increased circulating alkaline... 9 | 122
increased circulating chloride... 9 | 41
decreased circulating choleste... 8 | 93
decreased lean body mass 8 | 135
impaired glucose tolerance 8 | 75
decreased lymphocyte cell numb... 7 | 83
enlarged heart 7 | 210
short tibia 7 | 97
abnormal embryo size 6 | 220
abnormal eye morphology 6 | 68
abnormal gait 6 | 69
abnormal locomotor behavior 6 | 24
abnormal retina morphology 6 | 71
decreased circulating HDL chol... 6 | 68
decreased circulating alkaline... 6 | 46
decreased circulating serum al... 6 | 82
improved glucose tolerance 6 | 79
increased mean corpuscular vol... 6 | 92
increased startle reflex 6 | 112
limb grasping 6 | 41
prenatal lethality prior to he... 6 | 87
tremors 6 | 39
abnormal behavioral response t... 5 | 66
abnormal seminal vesicle morph... 5 | 114
abnormal sleep behavior 5 | 70
abnormal testis morphology 5 | 43
decreased circulating insulin ... 5 | 76
decreased circulating triglyce... 5 | 79
decreased mean corpuscular vol... 5 | 79
decreased neutrophil cell numb... 5 | 42
decreased startle reflex 5 | 75
hypoactivity 5 | 132
increased heart weight 5 | 62
persistence of hyaloid vascula... 5 | 33
prolonged QT interval 5 | 38
prolonged ST segment 5 | 36
small testis 5 | 58
abnormal epididymis morphology 4 | 42
abnormal heart morphology 4 | 162
decreased body length 4 | 101
increased circulating choleste... 4 | 66
increased circulating triglyce... 4 | 42
increased monocyte cell number 4 | 63
increased red blood cell distr... 4 | 34
abnormal bone mineralization 3 | 38
abnormal craniofacial morpholo... 3 | 33
abnormal cranium morphology 3 | 36
abnormal lens morphology 3 | 81
abnormal skin morphology 3 | 50
cataract 3 | 92
decreased bone mineral density 3 | 126
decreased circulating amylase ... 3 | 28
decreased mean corpuscular hem... 3 | 50
decreased pulmonary respirator... 3 | 5
edema 3 | 59
embryonic growth retardation 3 | 106
impaired righting response 3 | 26
increased blood urea nitrogen ... 3 | 48
increased body weight 3 | 25
increased bone mineral density 3 | 72
increased circulating iron lev... 3 | 30
increased erythrocyte cell num... 3 | 39
increased fasted circulating g... 3 | 76
increased grip strength 3 | 41
increased neutrophil cell numb... 3 | 46
increased prepulse inhibition 3 | 32
small superior vagus ganglion 3 | 74
thin ventricular wall 3 | 24
trunk curl 3 | 16
abnormal coat-hair pigmentatio... 2 | 64
abnormal cornea morphology 2 | 31
abnormal retinal vasculature m... 2 | 27
abnormal vertebrae morphology 2 | 18
decreased circulating creatini... 2 | 39
decreased circulating potassiu... 2 | 20
decreased hemoglobin content 2 | 68
decreased prepulse inhibition 2 | 82
increased circulating amylase ... 2 | 25
increased circulating potassiu... 2 | 29
increased circulating serum al... 2 | 22
increased circulating total pr... 2 | 28
increased hemoglobin content 2 | 45

Disease

Carcinoma 492 | 11,493
medulloblastoma, large-cell 378 | 6,241
glioblastoma 361 | 5,792
atypical teratoid / rhabdoid tumor 350 | 5,112
ependymoma 335 | 4,679
adult high grade glioma 292 | 3,801
ovarian cancer 280 | 8,520
osteosarcoma 273 | 7,950
psoriasis 266 | 6,694
Astrocytoma, Pilocytic 252 | 3,081
group 3 medulloblastoma 252 | 4,104
oligodendroglioma 245 | 2,850
primitive neuroectodermal tumor 225 | 3,035
Schizophrenia 217 | 1,160
astrocytic glioma 215 | 2,597
lung cancer 195 | 4,740
Kidney cancer 183 | 2,613
lung carcinoma 172 | 2,843
Pick disease 160 | 1,894
subependymal giant cell astrocytoma 160 | 2,287
Bipolar Disorder 147 | 666
Epilepsy 133 | 792
malignant mesothelioma 132 | 3,232
Breast cancer 129 | 3,578
pituitary cancer 122 | 1,972
intraductal papillary-mucinous neoplasm (IPMN) 115 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 111 | 2,955
Alzheimer's disease 109 | 658
invasive ductal carcinoma 105 | 2,951
Cancer 104 | 2,499
Depressive disorder 102 | 409
intraductal papillary-mucinous carcinoma (IPMC) 101 | 2,989
non-small cell lung cancer 98 | 2,890
Intellectual disability 96 | 1,016
Mental Depression 94 | 333
Alcoholic Intoxication, Chronic 88 | 289
group 4 medulloblastoma 86 | 1,855
lung adenocarcinoma 86 | 2,716
pancreatic cancer 86 | 2,398
interstitial cystitis 85 | 2,312
Parkinson's disease 83 | 392
Autistic Disorder 77 | 364
Seizures 77 | 596
colon cancer 72 | 1,478
Major Depressive Disorder 71 | 301
Autosomal recessive predisposition 70 | 1,442
diabetes mellitus 70 | 1,728
tuberculosis 70 | 2,010
cystic fibrosis 68 | 1,696
Liver cancer 67 | 604
astrocytoma 65 | 1,146
ductal carcinoma in situ 64 | 1,745
Toxic encephalopathy 63 | 141
Mood Disorders 62 | 184
Neurodegenerative disease 61 | 414
Unipolar Depression 60 | 250
breast carcinoma 58 | 1,638
ulcerative colitis 58 | 1,819
Melanoma 54 | 711
Obesity 53 | 678
Down syndrome 52 | 499
adrenocortical carcinoma 51 | 1,428
pediatric high grade glioma 50 | 1,064
Amyotrophic lateral sclerosis 49 | 451
Alcohol dependence 48 | 107
Dull intelligence 48 | 645
Low intelligence 48 | 645
Mental Retardation 48 | 645
Mental deficiency 48 | 645
Poor school performance 48 | 645
Skin cancer 48 | 469
Cognitive delay 46 | 608
Global developmental delay 46 | 608
Mental and motor retardation 46 | 608
Cocaine-Related Disorders 45 | 92
Neuropathy 44 | 261
General anesthesia 43 | 53
Muscle hypotonia 43 | 571
Rheumatoid arthritis 43 | 1,191
spina bifida 43 | 1,074
Dementia 42 | 175
primary pancreatic ductal adenocarcinoma 42 | 1,109
medulloblastoma 41 | 720
Attention deficit hyperactivity disorder 40 | 278
Hypertension 39 | 396
pancreatic ductal adenocarcinoma liver metastasis 39 | 1,962
Cerebrovascular disease 38 | 238
acute quadriplegic myopathy 38 | 1,158
cutaneous lupus erythematosus 36 | 1,057
juvenile dermatomyositis 36 | 1,187
Pain agnosia 35 | 104
aldosterone-producing adenoma 35 | 665
Huntington's disease 34 | 76
non primary Sjogren syndrome sicca 34 | 891
Anxiety 33 | 136
Endometrial cancer 33 | 311
Multiple myeloma 33 | 1,332
Status Epilepticus 32 | 98
Vascular disease 31 | 319
progressive supranuclear palsy 31 | 676

Tissue

Endocrine System 643 | 18,159
Nervous System 626 | 16,725
Digestive Tract 622 | 17,369
Female tissues 619 | 17,400
Skin and soft tissues 614 | 17,230
Male tissues 607 | 17,142
Liver and Pancreas 591 | 16,750
Urinary Tract 587 | 16,678
Blood and immune system 584 | 16,909
Respiratory system 565 | 16,393
Cardiovascular System 515 | 15,192

Target Family

Non-IDG 401 | 12,091
Enzyme 84 | 4,145
Ion Channel 80 | 344
GPCR 32 | 408
Transporter 28 | 473
Kinase 25 | 634
Transcription Factor 4 | 1,400
oGPCR 4 | 421
Epigenetic 3 | 242
Nuclear Receptor 1 | 48

Compartment GO Term

Synapse 662 | 662
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protocadherin-15 PCDH15 Tbio Non-IDG -1.83877 74.3 42
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
Leucine-rich glioma-inactivated protein 1 LGI1 Tbio Non-IDG -2.52790 342.7 207
Proline-rich membrane anchor 1 PRIMA1 Tbio Non-IDG -2.20803 151.5 6
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
Ras-related protein Rab-40C RAB40C Tbio Non-IDG -0.89913 7.57 111
Huntingtin HTT Tchem Non-IDG -3.36282 2294.8 599