Development Level

Tbio 15 | 11,445
Tchem 3 | 1,598
Tdark 3 | 6,588

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 5 | 979
decreased body weight 2 | 161
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
abnormal behavior 1 | 298
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased lean body mass 1 | 135
decreased vertical activity 1 | 208
increased circulating magnesiu... 1 | 10
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134

Disease

Carcinoma 17 | 11,493
ovarian cancer 16 | 8,520
lung cancer 11 | 4,740
Breast cancer 10 | 3,578
osteosarcoma 10 | 7,950
Cancer 9 | 2,499
group 3 medulloblastoma 9 | 4,104
Multiple myeloma 8 | 1,332
atypical teratoid / rhabdoid tumor 8 | 5,112
Kidney cancer 7 | 2,613
dermatomyositis 7 | 966
malignant mesothelioma 7 | 3,232
Waldenstrons macroglobulinemia 6 | 765
glioblastoma 6 | 5,792
invasive ductal carcinoma 6 | 2,951
medulloblastoma, large-cell 6 | 6,241
primitive neuroectodermal tumor 6 | 3,035
psoriasis 6 | 6,694
colon cancer 5 | 1,478
ependymoma 5 | 4,679
lung adenocarcinoma 5 | 2,716
Liver cancer 4 | 604
adult high grade glioma 4 | 3,801
ductal carcinoma in situ 4 | 1,745
Astrocytoma, Pilocytic 3 | 3,081
Cleft Palate 3 | 271
Connective tissue disease 3 | 62
Fetal Growth Retardation 3 | 189
Infant, Small for Gestational Age 3 | 176
Intellectual disability 3 | 1,016
Intrauterine retardation 3 | 176
Lupus erythematosus 3 | 57
Macrostomia 3 | 72
Rheumatoid arthritis 3 | 1,191
adrenocortical carcinoma 3 | 1,428
diabetes mellitus 3 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
pancreatic cancer 3 | 2,398
subependymal giant cell astrocytoma 3 | 2,287
Adenoid Cystic Carcinoma 2 | 99
Alpha thalassemia 2 | 10
Brachydactyly 2 | 156
Broad flat nasal bridge 2 | 236
Carcinoma, Adenoid Cystic 2 | 99
Cockayne syndrome 2 | 60
Coffin-Siris syndrome 2 | 17
Cognitive delay 2 | 608
Cryptorchidism 2 | 296
Dental caries 2 | 164
Dull intelligence 2 | 645
Enamel erosion 2 | 19
Endometrial cancer 2 | 311
Endometriosis 2 | 540
Epilepsy 2 | 792
Feeding difficulties in infancy 2 | 175
Full lower lip 2 | 64
Gaucher disease type 1 2 | 180
Generalized hirsutism 2 | 36
Gingivitis 2 | 29
Global developmental delay 2 | 608
Immune system cancer 2 | 140
Joint hyperflexibility 2 | 78
Long eyelashes 2 | 37
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Nasal bridge wide 2 | 236
Parkinson's disease 2 | 392
Poor school performance 2 | 645
Prominent lower lip 2 | 64
Retinitis pigmentosa 20 2 | 5
Schimke immuno-osseous dysplasia 2 | 8
Schizophrenia 2 | 1,160
Seizures 2 | 596
Short stature 2 | 531
Small head 2 | 374
Spondyloepiphyseal dysplasia with congenital joint dislocations 2 | 13
Thyroiditis 2 | 29
Triangular face 2 | 58
aldosterone-producing adenoma 2 | 665
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
gastric carcinoma 2 | 807
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
juvenile dermatomyositis 2 | 1,187
non primary Sjogren syndrome sicca 2 | 891
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
spina bifida 2 | 1,074
3-M syndrome 1 | 15
Cerebellar hypoplasia and atrophy 1 | 41
Hyperplasia of nose 1 | 23
Hypertrophy of nose 1 | 23
Large nose 1 | 23
Mucositis 1 | 29
Myocardial Infarction 1 | 151

Tissue

Blood and immune system 21 | 16,909
Cardiovascular System 21 | 15,192
Digestive Tract 21 | 17,369
Endocrine System 21 | 18,159
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Nervous System 21 | 16,725
Respiratory system 21 | 16,393
Skin and soft tissues 21 | 17,230
Urinary Tract 21 | 16,678

Target Family

Non-IDG 13 | 12,091
Epigenetic 5 | 242
Enzyme 2 | 4,145
Kinase 1 | 634

Compartment GO Term

Swr1 complex 21 | 21
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Acidic leucine-rich nuclear phosphoprotein 32 family member E ANP32E Tbio Non-IDG -0.82034 5.60 97
Inhibitor of growth protein 3 ING3 Tbio Epigenetic -2.33680 199.4 175
Mitogen-activated protein kinase kinase kinase 21 MAP3K21 Tdark Kinase -0.42420 4.24 174
Helicase SRCAP SRCAP Tbio Enzyme -1.89315 84.2 67
Bromodomain-containing protein 8 BRD8 Tbio Epigenetic -0.69185 6.07 117
Histone H2A type 2-C HIST2H2AC Tbio Non-IDG -3.03938 994.7 101
Histone H2B type 2-E HIST2H2BE Tbio Non-IDG -3.48425 2920.0 135
Histone H2A type 2-A HIST2H2AA3 Tbio Non-IDG -3.04065 999.3 88
Vacuolar protein sorting-associated protein 72 homolog VPS72 Tbio Non-IDG -2.17465 143.5 142
Transformation/transcription domain-associated protein TRRAP Tbio Non-IDG -1.62460 39.0 162