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Development Level

Tbio 17 | 11,445
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
decreased body length 2 | 101
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal heart morphology 1 | 162
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
decreased circulating glucose ... 1 | 126
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged heart 1 | 210
small testis 1 | 58

Disease

osteosarcoma 10 | 7,950
medulloblastoma, large-cell 9 | 6,241
Carcinoma 7 | 11,493
ovarian cancer 7 | 8,520
Friedreich ataxia 5 | 24
lung cancer 5 | 4,740
psoriasis 5 | 6,694
Autosomal recessive predisposition 4 | 1,442
non-small cell lung cancer 4 | 2,890
Breast cancer 3 | 3,578
Molybdenum Cofactor Deficiency, Complementation Group A 3 | 4
Nystagmus 3 | 317
Sideroblastic anemia 3 | 20
Thick vermilion border 3 | 25
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
malignant mesothelioma 3 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Axonal loss 2 | 7
Big calvaria 2 | 147
Cerebral atrophy 2 | 178
Chubby cheeks 2 | 50
Colitis 2 | 54
Combined molybdoflavoprotein enzyme deficiency 2 | 3
Crohn's disease 2 | 321
Degenerative brain disorder 2 | 100
Dilated ventricles (finding) 2 | 121
Ectopia Lentis 2 | 17
Encephalomalacia 2 | 3
Frontal bossing 2 | 157
Full cheeks 2 | 50
Gliosis 2 | 56
Growth delay 2 | 114
Growth failure 2 | 114
Growth retardation 2 | 115
Hyperplasia of cheeks 2 | 50
Hypertrophy of cheeks 2 | 50
Hypoplasia of corpus callosum 2 | 90
Hypouricemia 2 | 5
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Increased urinary hypoxanthine 2 | 2
Increased urinary taurine 2 | 2
Intellectual disability 2 | 1,016
Long face 2 | 71
Long philtrum 2 | 137
Molybdenum Cofactor Deficiency, Complementation Group B 2 | 2
Muscle Weakness 2 | 170
Myoclonic spasms 2 | 2
Opisthotonus 2 | 14
Orbital separation excessive 2 | 244
Peripheral demyelination 2 | 16
Pick disease 2 | 1,894
Poor growth 2 | 114
Progressive disorder 2 | 142
Puffy cheeks 2 | 50
Short nose 2 | 132
Small head 2 | 374
Small nose 2 | 132
Spastic Quadriplegia 2 | 42
Supratentorial atrophy 2 | 94
Very poor growth 2 | 114
Xanthine stones 2 | 3
Xanthinuria 2 | 10
active Crohn's disease 2 | 922
adult high grade glioma 2 | 3,801
atypical teratoid / rhabdoid tumor 2 | 5,112
ductal carcinoma in situ 2 | 1,745
hereditary spastic paraplegia 2 | 318
invasive ductal carcinoma 2 | 2,951
sonic hedgehog group medulloblastoma 2 | 467
tuberculosis 2 | 2,010
tuberculosis and treatment for 6 months 2 | 409
ulcerative colitis 2 | 1,819
Abnormal visual evoked potential 1 | 26
Acquired immunodeficiency syndrome 1 | 197
Ataxia, Appendicular 1 | 25
Cardiomegaly 1 | 116
Cerebellar Dysmetria 1 | 56
Decreased sensory nerve conduction velocities (NCV) 1 | 8
Dyspnea 1 | 76
Ethylmalonic encephalopathy 1 | 12
Gait imbalance 1 | 17
Hair shaft abnormalities 1 | 30
Hypotrophic malar bone 1 | 129
Increased intramyocellular lipid droplets 1 | 13
Learning disability 1 | 17
Malar flattening 1 | 129
Mastitis 1 | 48
Scoliosis 1 | 44
Sensory neuropathy 1 | 20
Spastic Ataxia 1 | 18
Thyroid cancer 1 | 36
Toxic shock syndrome 1 | 28
hair abnormalities (non-specific) 1 | 30
inflammatory breast cancer 1 | 286
sarcoidosis 1 | 370

Tissue

Blood and immune system 17 | 16,909
Cardiovascular System 17 | 15,192
Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Male tissues 17 | 17,142
Nervous System 17 | 16,725
Respiratory system 17 | 16,393
Skin and soft tissues 17 | 17,230
Urinary Tract 17 | 16,678

Target Family

Non-IDG 12 | 12,091
Enzyme 6 | 4,145

Compartment GO Term

Sulfurtransferase complex 18 | 18
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cysteine desulfurase, mitochondrial NFS1 Tbio Enzyme -1.70267 46.3 131
LYR motif-containing protein 4 LYRM4 Tbio Non-IDG -1.25062 16.6 69
Molybdenum cofactor biosynthesis protein 1 MOCS1 Tbio Non-IDG -1.28570 20.9 138
Iron-sulfur cluster co-chaperone protein HscB, mitochondrial HSCB Tbio Non-IDG -1.63830 47.3 42
Nuclear export mediator factor NEMF NEMF Tbio Non-IDG -0.93499 7.71 157
Transmembrane protein 201 TMEM201 Tdark Non-IDG -2.07296 119.8 17
Thiosulfate sulfurtransferase TST Tbio Enzyme -2.35239 208.6 79
Frataxin, mitochondrial FXN Tbio Non-IDG -3.02739 1114.8 403
3-mercaptopyruvate sulfurtransferase MPST Tbio Enzyme -1.85628 72.4 79
Iron-sulfur cluster assembly enzyme ISCU, mitochondrial ISCU Tbio Non-IDG -2.25839 167.3 167