Development Level

Tbio 55 | 11,651
Tdark 7 | 6,593

IMPC Phenotype

increased or absent threshold ... 7 | 101
absent startle reflex 5 | 24
increased circulating sodium l... 5 | 71
abnormal behavior 4 | 298
decreased body weight 4 | 161
decreased prepulse inhibition 4 | 82
decreased startle reflex 4 | 75
preweaning lethality, incomple... 4 | 499
absent pinna reflex 3 | 23
decreased circulating amylase ... 3 | 28
decreased circulating triglyce... 3 | 79
hyperactivity 3 | 148
increased lean body mass 3 | 172
tremors 3 | 39
trunk curl 3 | 16
abnormal bone structure 2 | 187
abnormal ear morphology 2 | 9
abnormal locomotor activation 2 | 16
abnormal vibrissa morphology 2 | 25
decreased grip strength 2 | 116
decreased leukocyte cell numbe... 2 | 73
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
impaired righting response 2 | 26
increased blood urea nitrogen ... 2 | 48
increased circulating alkaline... 2 | 122
increased circulating chloride... 2 | 41
increased circulating triglyce... 2 | 42
increased heart weight 2 | 62
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 96
increased thermal nociceptive ... 2 | 9
increased total body fat amoun... 2 | 134
increased vertical activity 2 | 24
limb grasping 2 | 41
stereotypic behavior 2 | 3
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal coping response 1 | 1
abnormal digestive system phys... 1 | 1
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal locomotor behavior 1 | 24
abnormal response to tactile s... 1 | 17
abnormal startle reflex 1 | 15
abnormal whole-body plethysmog... 1 | 4
convulsive seizures 1 | 13
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating potassiu... 1 | 20
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
female infertility 1 | 60
head bobbing 1 | 5
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased kidney weight 1 | 6
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased urine magnesium leve... 1 | 2
mammalian phenotype 1 | 17
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
short tibia 1 | 97
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
thrombocytopenia 1 | 56

Disease

Carcinoma 49 | 11,493
Nonsyndromic deafness 39 | 142
psoriasis 24 | 6,694
osteosarcoma 23 | 7,950
medulloblastoma, large-cell 20 | 6,241
Sensorineural hearing loss 19 | 106
ependymoma 19 | 4,679
Autosomal recessive predisposition 18 | 1,442
ovarian cancer 18 | 8,520
glioblastoma 17 | 5,792
Kidney cancer 15 | 2,613
Astrocytoma, Pilocytic 14 | 3,081
atypical teratoid / rhabdoid tumor 14 | 5,112
Usher syndrome 13 | 32
Breast cancer 12 | 3,578
adult high grade glioma 12 | 3,801
group 3 medulloblastoma 12 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
pituitary cancer 12 | 1,972
Retinitis Pigmentosa 11 | 226
lung cancer 11 | 4,740
Sensorineural Hearing Loss (disorder) 10 | 284
astrocytic glioma 10 | 2,597
lung adenocarcinoma 10 | 2,716
lung carcinoma 10 | 2,843
malignant mesothelioma 10 | 3,232
pancreatic cancer 10 | 2,398
Blindness 9 | 88
Liver cancer 9 | 604
interstitial cystitis 9 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
invasive ductal carcinoma 9 | 2,951
Hodgkin's lymphoma, nodular sclerosis 8 | 22
Melanoma 8 | 711
oligodendroglioma 8 | 2,850
primitive neuroectodermal tumor 8 | 3,035
Cataract 7 | 297
Difficulties with night vision 7 | 87
Dull intelligence 7 | 645
Electroretinogram abnormal 7 | 95
Intellectual disability 7 | 1,016
Lens Opacities 7 | 231
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Night Blindness 7 | 101
Pick disease 7 | 1,894
Poor school performance 7 | 645
Skin cancer 7 | 469
group 4 medulloblastoma 7 | 1,855
non-small cell lung cancer 7 | 2,890
Abnormal vision 6 | 52
Cancer 6 | 2,499
Hemianopsia 6 | 15
Pigmentary iris degeneration 6 | 20
Retinal blind spot 6 | 11
Schizophrenia 6 | 1,160
Scotoma 6 | 22
Usher Syndrome, Type 1 6 | 7
cystic fibrosis 6 | 1,696
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
spina bifida 6 | 1,074
subependymal giant cell astrocytoma 6 | 2,287
tuberculosis 6 | 2,010
Deafness 5 | 198
Endometrial cancer 5 | 311
Usher Syndrome, Type I 5 | 6
Usher Syndrome, Type II 5 | 5
Usher syndrome type 2 5 | 5
ductal carcinoma in situ 5 | 1,745
nasopharyngeal carcinoma 5 | 1,058
pediatric high grade glioma 5 | 1,064
ulcerative colitis 5 | 1,819
Abnormality of cochlea 4 | 6
Cerebellar Ataxia 4 | 304
Cognitive delay 4 | 608
Endometriosis 4 | 540
Global developmental delay 4 | 608
High-grade hypermetropia 4 | 24
Mental and motor retardation 4 | 608
Prenatal onset 4 | 139
Rheumatoid arthritis 4 | 1,191
Vestibular hypofunction 4 | 7
acute quadriplegic myopathy 4 | 1,158
aldosterone-producing adenoma 4 | 665
astrocytoma 4 | 1,146
breast carcinoma 4 | 1,638
chronic rhinosinusitis 4 | 512
colon cancer 4 | 1,478
dermatomyositis 4 | 966
esophageal adenocarcinoma 4 | 737
gastric carcinoma 4 | 807
medulloblastoma 4 | 720
sonic hedgehog group medulloblastoma 4 | 467
Broad flat nasal bridge 3 | 236
Down syndrome 3 | 499
Glaucoma 3 | 239
Type 2 diabetes mellitus 3 | 272
adrenocortical carcinoma 3 | 1,428

Tissue

Endocrine System 57 | 18,159
Male tissues 56 | 17,142
Digestive Tract 55 | 17,369
Skin and soft tissues 55 | 17,230
Female tissues 54 | 17,400
Nervous System 54 | 16,725
Liver and Pancreas 52 | 16,750
Blood and immune system 48 | 16,909
Urinary Tract 48 | 16,678
Respiratory system 46 | 16,393
Cardiovascular System 41 | 15,192

Target Family

Non-IDG 44 | 12,091
Enzyme 7 | 4,145
Transcription Factor 3 | 1,400
Transporter 3 | 473
Ion Channel 2 | 344
Kinase 2 | 634
GPCR 1 | 408

Compartment GO Term

Stereocilium bundle 62 | 62
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Unconventional myosin-VIIb MYO7B Tbio Non-IDG -0.65885 5.07 14
KICSTOR complex protein kaptin KPTN Tbio Non-IDG -1.45875 26.8 153
Taperin TPRN Tbio Non-IDG -0.79018 6.82 33
Plasma membrane calcium-transporting ATPase 2 ATP2B2 Tbio Transporter -2.07505 125.1 76
Dual specificity protein phosphatase CDC14A CDC14A Tbio Enzyme -2.31524 216.3 245
Unconventional myosin-VI MYO6 Tbio Non-IDG -1.72509 54.2 108
G-protein coupled receptor 98 ADGRV1 Tbio GPCR -2.51228 316.6 64
Unconventional myosin-XV MYO15A Tbio Non-IDG -1.64094 42.8 15
Epidermal growth factor receptor kinase substrate 8 EPS8 Tbio Enzyme -1.84834 81.7 254
MORN repeat-containing protein 4 MORN4 Tdark Non-IDG -0.12494 1.89 33