Development Level

Tbio 44 | 10,625
Tdark 5 | 7,003
Tchem 2 | 1,890

IMPC Term

increased or absent threshold ... 6 | 128
absent startle reflex 5 | 15
decreased prepulse inhibition 5 | 52
decreased startle reflex 5 | 48
abnormal behavior 3 | 226
absent pinna reflex 3 | 21
decreased circulating HDL chol... 3 | 77
decreased circulating amylase ... 3 | 24
decreased circulating choleste... 3 | 85
decreased circulating triglyce... 3 | 83
decreased grip strength 3 | 123
increased circulating alkaline... 3 | 119
increased circulating chloride... 3 | 43
increased circulating sodium l... 3 | 71
trunk curl 3 | 15
abnormal bone structure 2 | 131
abnormal ear morphology 2 | 5
abnormal locomotor activation 2 | 26
decreased body length 2 | 108
decreased body weight 2 | 174
decreased circulating free fat... 2 | 39
decreased circulating glucose ... 2 | 121
decreased lean body mass 2 | 195
decreased total body fat amoun... 2 | 186
hyperactivity 2 | 108
impaired righting response 2 | 19
increased blood urea nitrogen ... 2 | 44
increased hemoglobin content 2 | 45
increased lean body mass 2 | 107
increased mean corpuscular hem... 2 | 93
limb grasping 2 | 35
stereotypic behavior 2 | 3
abnormal behavioral response t... 1 | 52
abnormal bone mineralization 1 | 55
abnormal coping response 1 | 12
abnormal digestive system phys... 1 | 1
abnormal embryo size 1 | 112
abnormal gait 1 | 51
abnormal glucose homeostasis 1 | 5
abnormal heart left ventricle ... 1 | 20
abnormal motor coordination/ b... 1 | 4
abnormal posture 1 | 5
abnormal respiratory quotient 1 | 9
abnormal response to tactile s... 1 | 16
abnormal sleep behavior 1 | 63
abnormal startle reflex 1 | 14
abnormal vibrissa morphology 1 | 17
circling 1 | 1
convulsive seizures 1 | 11
decreased B cell number 1 | 30
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating glycerol... 1 | 19
decreased circulating insulin ... 1 | 75
decreased circulating potassiu... 1 | 17
decreased hemoglobin content 1 | 53
decreased leukocyte cell numbe... 1 | 54
decreased spleen weight 1 | 13
head bobbing 1 | 3
impaired pupillary reflex 1 | 14
improved glucose tolerance 1 | 56
increased NK T cell number 1 | 11
increased body weight 1 | 42
increased bone mineral content 1 | 92
increased circulating HDL chol... 1 | 63
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating serum al... 1 | 25
increased circulating total pr... 1 | 20
increased mean corpuscular vol... 1 | 91
increased mean platelet volume 1 | 19
increased rib number 1 | 41
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 57
increased vertical activity 1 | 18
persistence of hyaloid vascula... 1 | 22
polycystic kidney 1 | 9
preweaning lethality, incomple... 1 | 260
sclerocornea 1 | 2
short tibia 1 | 82
straub tail 1 | 26
thrombocytopenia 1 | 46
tremors 1 | 34

Disease

Nonsyndromic deafness 33 | 121
psoriasis 22 | 6,685
Sensorineural hearing loss 19 | 107
osteosarcoma 18 | 7,933
medulloblastoma, large-cell 16 | 6,234
Carcinoma 14 | 2,147
glioblastoma 13 | 5,572
Usher syndrome 12 | 34
ovarian cancer 12 | 8,484
Retinitis pigmentosa 11 | 153
pituitary cancer 11 | 1,972
atypical teratoid / rhabdoid tumor 10 | 4,369
pilocytic astrocytoma 10 | 3,086
sonic hedgehog group medulloblastoma 10 | 1,482
Blindness 9 | 84
Hodgkin's lymphoma, nodular sclerosis 9 | 24
astrocytic glioma 9 | 2,241
ependymoma 9 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,988
invasive ductal carcinoma 9 | 2,950
adult high grade glioma 8 | 2,148
group 4 medulloblastoma 8 | 1,875
lung carcinoma 8 | 2,844
malignant mesothelioma 8 | 3,162
oligodendroglioma 8 | 2,849
Breast cancer 7 | 3,094
Pick disease 7 | 1,893
interstitial cystitis 7 | 2,299
primitive neuroectodermal tumor 7 | 3,031
cystic fibrosis 6 | 1,665
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,289
lung cancer 6 | 4,466
non-small cell lung cancer 6 | 2,798
pediatric high grade glioma 6 | 2,712
lung adenocarcinoma 5 | 2,713
pancreatic cancer 5 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
posterior fossa group A ependymoma 5 | 1,511
spina bifida 5 | 1,064
subependymal giant cell astrocytoma 5 | 2,287
ulcerative colitis 5 | 2,087
Usher Syndrome, Type II 4 | 4
Usher syndrome type 2 4 | 4
acute quadriplegic myopathy 4 | 1,157
aldosterone-producing adenoma 4 | 664
breast carcinoma 4 | 1,614
ductal carcinoma in situ 4 | 1,745
esophageal adenocarcinoma 4 | 737
gastric carcinoma 4 | 832
group 3 medulloblastoma 4 | 2,254
medulloblastoma 4 | 1,524
posterior fossa group B ependymoma 4 | 1,530
tuberculosis 4 | 1,557
Cancer 3 | 2,346
Leber congenital amaurosis 3 | 72
Rheumatoid Arthritis 3 | 1,160
adrenocortical carcinoma 3 | 1,427
astrocytoma 3 | 1,493
atypical teratoid/rhabdoid tumor 3 | 1,095
dermatomyositis 3 | 933
nasopharyngeal carcinoma 3 | 1,056
Atopic dermatitis 2 | 944
Deafness 2 | 18
Deafness, Autosomal Recessive 12 2 | 2
Down syndrome 2 | 548
Dyslexia 2 | 36
Endometriosis 2 | 535
Gaucher disease type 3 2 | 76
Male infertility 2 | 170
Substance-Related Disorders 2 | 114
USHER SYNDROME, TYPE ID 2 | 2
USHER SYNDROME, TYPE IIA 2 | 2
USHER SYNDROME, TYPE IIC, GPR98/PDZD7, DIGENIC 2 | 2
Usher syndrome, type 1D 2 | 2
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
colon cancer 2 | 1,475
cone-rod dystrophy 2 | 56
cutaneous lupus erythematosus 2 | 1,056
juvenile dermatomyositis 2 | 1,189
mucosa-associated lymphoid tissue lymphoma 2 | 480
non primary Sjogren syndrome sicca 2 | 840
primary pancreatic ductal adenocarcinoma 2 | 1,271
Adenocarcinoma 1 | 115
Alcohol dependence 1 | 107
Deafness, Autosomal Recessive 23 1 | 1
Deafness, Autosomal Recessive 3 1 | 1
Entropion 1 | 12
Fuchs' endothelial dystrophy 1 | 20
Fundus dystrophy 1 | 77
Intracranial aneurysm 1 | 20
MENTAL RETARDATION, AUTOSOMAL RECESSIVE 41 1 | 1
Melanoma 1 | 261
Neoplasm Invasiveness 1 | 127
Refractive Errors 1 | 18
Renal tubular acidosis 1 | 14
USHER SYNDROME, TYPE IG 1 | 2
Usher Syndrome, Type IF 1 | 1
Usher syndrome, type 1F 1 | 1
Vitiligo 1 | 71

Tissue

Digestive Tract 50 | 18,473
Endocrine System 50 | 18,512
Female tissues 50 | 18,647
Nervous System 50 | 18,561
Urinary Tract 50 | 18,444
Liver and Pancreas 49 | 18,136
Skin and soft tissues 49 | 18,115
Blood and immune system 47 | 17,995
Cardiovascular System 47 | 17,958
Male tissues 46 | 17,969
Respiratory system 44 | 17,484

Target Family

Non-IDG 34 | 11,971
Enzyme 5 | 4,146
Transcription Factor 4 | 1,400
Transporter 3 | 473
Ion Channel 2 | 341
Kinase 2 | 634
GPCR 1 | 406

Compartment GO Term

Stereocilium 51 | 51
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Stereocilin STRC Tbio Non-IDG 35.9 7
Epidermal growth factor receptor kinase substrate 8 EPS8 Tbio Enzyme -1.80380 77.2 248
BarH-like 1 homeobox protein BARHL1 Tbio Transcription Factor -1.06351 11.8 78
Carcinoembryonic antigen-related cell adhesion molecule 16 CEACAM16 Tbio Non-IDG -0.73655 11.1 64
Lipoxygenase homology domain-containing protein 1 LOXHD1 Tbio Enzyme -0.76399 6.47 8
Plasma membrane calcium-transporting ATPase 2 ATP2B2 Tbio Transporter -2.03165 116.3 74
Taperin TPRN Tbio Non-IDG -0.72520 6.12 29
Sodium bicarbonate cotransporter 3 SLC4A7 Tchem Transporter -1.65486 53.5 119
Harmonin USH1C Tbio Non-IDG -2.04033 115.8 173
Glutaredoxin domain-containing cysteine-rich protein 1 GRXCR1 Tdark Non-IDG -0.62411 4.29 35