Development Level

Tbio 52 | 11,445
Tdark 5 | 6,588

IMPC Phenotype

increased or absent threshold ... 7 | 101
absent startle reflex 5 | 24
increased circulating sodium l... 5 | 71
abnormal behavior 4 | 298
decreased body weight 4 | 161
decreased prepulse inhibition 4 | 82
decreased startle reflex 4 | 75
absent pinna reflex 3 | 23
decreased circulating amylase ... 3 | 28
decreased circulating triglyce... 3 | 79
hyperactivity 3 | 148
increased lean body mass 3 | 172
preweaning lethality, incomple... 3 | 499
tremors 3 | 39
trunk curl 3 | 16
abnormal bone structure 2 | 187
abnormal ear morphology 2 | 9
abnormal locomotor activation 2 | 16
abnormal vibrissa morphology 2 | 25
decreased grip strength 2 | 116
decreased leukocyte cell numbe... 2 | 73
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
impaired righting response 2 | 26
increased blood urea nitrogen ... 2 | 48
increased circulating alkaline... 2 | 122
increased circulating chloride... 2 | 41
increased circulating triglyce... 2 | 42
increased heart weight 2 | 62
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 96
increased thermal nociceptive ... 2 | 9
increased total body fat amoun... 2 | 134
increased vertical activity 2 | 24
limb grasping 2 | 41
stereotypic behavior 2 | 3
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal coping response 1 | 1
abnormal digestive system phys... 1 | 1
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal locomotor behavior 1 | 24
abnormal response to tactile s... 1 | 17
abnormal startle reflex 1 | 15
abnormal whole-body plethysmog... 1 | 4
convulsive seizures 1 | 13
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating potassiu... 1 | 20
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
female infertility 1 | 60
head bobbing 1 | 5
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased kidney weight 1 | 6
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased urine magnesium leve... 1 | 2
mammalian phenotype 1 | 17
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
short tibia 1 | 97
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
thrombocytopenia 1 | 56

Disease

Carcinoma 44 | 11,493
Nonsyndromic deafness 35 | 142
psoriasis 23 | 6,694
osteosarcoma 22 | 7,950
Sensorineural hearing loss 19 | 106
medulloblastoma, large-cell 18 | 6,241
ependymoma 17 | 4,679
Autosomal recessive predisposition 16 | 1,442
glioblastoma 16 | 5,792
ovarian cancer 16 | 8,520
Astrocytoma, Pilocytic 14 | 3,081
Kidney cancer 14 | 2,613
atypical teratoid / rhabdoid tumor 14 | 5,112
Usher syndrome 13 | 32
adult high grade glioma 12 | 3,801
group 3 medulloblastoma 12 | 4,104
Retinitis Pigmentosa 11 | 226
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
pituitary cancer 11 | 1,972
Breast cancer 10 | 3,578
astrocytic glioma 10 | 2,597
lung cancer 10 | 4,740
lung carcinoma 10 | 2,843
pancreatic cancer 10 | 2,398
Blindness 9 | 88
Liver cancer 9 | 604
invasive ductal carcinoma 9 | 2,951
malignant mesothelioma 9 | 3,232
Hodgkin's lymphoma, nodular sclerosis 8 | 22
Sensorineural Hearing Loss (disorder) 8 | 284
interstitial cystitis 8 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
oligodendroglioma 8 | 2,850
primitive neuroectodermal tumor 8 | 3,035
Cataract 7 | 297
Difficulties with night vision 7 | 87
Dull intelligence 7 | 645
Electroretinogram abnormal 7 | 95
Intellectual disability 7 | 1,016
Lens Opacities 7 | 231
Low intelligence 7 | 645
Melanoma 7 | 711
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Night Blindness 7 | 101
Pick disease 7 | 1,894
Poor school performance 7 | 645
lung adenocarcinoma 7 | 2,716
Abnormal vision 6 | 52
Cancer 6 | 2,499
Hemianopsia 6 | 15
Pigmentary iris degeneration 6 | 20
Retinal blind spot 6 | 11
Scotoma 6 | 22
Skin cancer 6 | 469
Usher Syndrome, Type 1 6 | 7
group 4 medulloblastoma 6 | 1,855
non-small cell lung cancer 6 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
spina bifida 6 | 1,074
subependymal giant cell astrocytoma 6 | 2,287
tuberculosis 6 | 2,010
Deafness 5 | 198
Schizophrenia 5 | 1,160
Usher Syndrome, Type I 5 | 6
Usher Syndrome, Type II 5 | 5
Usher syndrome type 2 5 | 5
cystic fibrosis 5 | 1,696
ductal carcinoma in situ 5 | 1,745
pediatric high grade glioma 5 | 1,064
Abnormality of cochlea 4 | 6
Cerebellar Ataxia 4 | 304
Cognitive delay 4 | 608
Endometrial cancer 4 | 311
Global developmental delay 4 | 608
High-grade hypermetropia 4 | 24
Mental and motor retardation 4 | 608
Prenatal onset 4 | 139
Vestibular hypofunction 4 | 7
acute quadriplegic myopathy 4 | 1,158
aldosterone-producing adenoma 4 | 665
astrocytoma 4 | 1,146
breast carcinoma 4 | 1,638
dermatomyositis 4 | 966
esophageal adenocarcinoma 4 | 737
gastric carcinoma 4 | 807
medulloblastoma 4 | 720
nasopharyngeal carcinoma 4 | 1,058
sonic hedgehog group medulloblastoma 4 | 467
ulcerative colitis 4 | 1,819
Anteverted nostril 3 | 191
Broad flat nasal bridge 3 | 236
Down syndrome 3 | 499
Glaucoma 3 | 239
Infantile onset 3 | 238
Nasal bridge wide 3 | 236
Type 2 diabetes mellitus 3 | 272
adrenocortical carcinoma 3 | 1,428
colon cancer 3 | 1,478

Tissue

Endocrine System 52 | 18,159
Male tissues 52 | 17,142
Digestive Tract 51 | 17,369
Skin and soft tissues 51 | 17,230
Female tissues 50 | 17,400
Nervous System 50 | 16,725
Liver and Pancreas 48 | 16,750
Blood and immune system 45 | 16,909
Urinary Tract 44 | 16,678
Respiratory system 42 | 16,393
Cardiovascular System 39 | 15,192

Target Family

Non-IDG 40 | 12,091
Enzyme 6 | 4,145
Transcription Factor 3 | 1,400
Transporter 3 | 473
Ion Channel 2 | 344
Kinase 2 | 634
GPCR 1 | 408

Compartment GO Term

Stereocilium 57 | 57
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protocadherin-15 PCDH15 Tbio Non-IDG -1.83877 74.3 42
Unconventional myosin-XV MYO15A Tbio Non-IDG -1.64094 42.8 15
Sodium bicarbonate cotransporter 3 SLC4A7 Tbio Transporter -1.82039 64.7 133
Harmonin USH1C Tbio Non-IDG -2.10689 124.7 188
G-protein coupled receptor 98 ADGRV1 Tbio GPCR -2.51228 316.6 64
Myosin-IIIb MYO3B Tbio Kinase -0.73450 5.14 127
Beta-tectorin TECTB Tbio Non-IDG -1.23705 16.8 72
Glutaredoxin domain-containing cysteine-rich protein 2 GRXCR2 Tbio Non-IDG 0.00000 1.00 14
Unconventional myosin-VIIa MYO7A Tbio Non-IDG -2.14713 133.5 129
Putative stereocilin-like protein STRCP1 Tdark Non-IDG -1.30533 34.5 0