Development Level

Tbio 44 | 10,625
Tdark 5 | 7,003
Tchem 2 | 1,890

IMPC Phenotype

increased or absent threshold ... 6 | 128
absent startle reflex 5 | 15
decreased prepulse inhibition 5 | 52
decreased startle reflex 5 | 48
abnormal behavior 3 | 226
absent pinna reflex 3 | 21
decreased circulating HDL chol... 3 | 77
decreased circulating amylase ... 3 | 24
decreased circulating choleste... 3 | 85
decreased circulating triglyce... 3 | 83
decreased grip strength 3 | 123
increased circulating alkaline... 3 | 119
increased circulating chloride... 3 | 43
increased circulating sodium l... 3 | 71
trunk curl 3 | 15
abnormal bone structure 2 | 131
abnormal ear morphology 2 | 5
abnormal locomotor activation 2 | 26
decreased body length 2 | 108
decreased body weight 2 | 174
decreased circulating free fat... 2 | 39
decreased circulating glucose ... 2 | 121
decreased lean body mass 2 | 195
decreased total body fat amoun... 2 | 186
hyperactivity 2 | 108
impaired righting response 2 | 19
increased blood urea nitrogen ... 2 | 44
increased hemoglobin content 2 | 45
increased lean body mass 2 | 107
increased mean corpuscular hem... 2 | 93
limb grasping 2 | 35
stereotypic behavior 2 | 3
abnormal behavioral response t... 1 | 52
abnormal bone mineralization 1 | 55
abnormal coping response 1 | 12
abnormal digestive system phys... 1 | 1
abnormal embryo size 1 | 112
abnormal gait 1 | 51
abnormal glucose homeostasis 1 | 5
abnormal heart left ventricle ... 1 | 20
abnormal motor coordination- b... 1 | 4
abnormal posture 1 | 5
abnormal respiratory quotient 1 | 9
abnormal response to tactile s... 1 | 16
abnormal sleep behavior 1 | 63
abnormal startle reflex 1 | 14
abnormal vibrissa morphology 1 | 17
circling 1 | 1
convulsive seizures 1 | 11
decreased B cell number 1 | 30
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating glycerol... 1 | 19
decreased circulating insulin ... 1 | 75
decreased circulating potassiu... 1 | 17
decreased hemoglobin content 1 | 53
decreased leukocyte cell numbe... 1 | 54
decreased spleen weight 1 | 13
head bobbing 1 | 3
impaired pupillary reflex 1 | 14
improved glucose tolerance 1 | 56
increased NK T cell number 1 | 11
increased body weight 1 | 42
increased bone mineral content 1 | 92
increased circulating HDL chol... 1 | 63
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating serum al... 1 | 25
increased circulating total pr... 1 | 20
increased mean corpuscular vol... 1 | 91
increased mean platelet volume 1 | 19
increased rib number 1 | 41
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 57
increased vertical activity 1 | 18
persistence of hyaloid vascula... 1 | 22
polycystic kidney 1 | 9
preweaning lethality, incomple... 1 | 260
sclerocornea 1 | 2
short tibia 1 | 82
straub tail 1 | 26
thrombocytopenia 1 | 46
tremors 1 | 34

Disease

Nonsyndromic deafness 33 | 121
psoriasis 22 | 6,685
Sensorineural hearing loss 19 | 107
osteosarcoma 18 | 7,933
medulloblastoma, large-cell 16 | 6,234
Carcinoma 14 | 2,147
glioblastoma 13 | 5,572
Usher syndrome 12 | 34
ovarian cancer 12 | 8,491
Retinitis pigmentosa 11 | 156
pituitary cancer 11 | 1,972
atypical teratoid / rhabdoid tumor 10 | 4,369
pilocytic astrocytoma 10 | 3,086
sonic hedgehog group medulloblastoma 10 | 1,482
Blindness 9 | 84
Hodgkin's lymphoma, nodular sclerosis 9 | 24
astrocytic glioma 9 | 2,241
ependymoma 9 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,988
invasive ductal carcinoma 9 | 2,950
adult high grade glioma 8 | 2,148
group 4 medulloblastoma 8 | 1,875
lung carcinoma 8 | 2,844
malignant mesothelioma 8 | 3,163
oligodendroglioma 8 | 2,849
Breast cancer 7 | 3,098
Pick disease 7 | 1,893
interstitial cystitis 7 | 2,299
primitive neuroectodermal tumor 7 | 3,031
Usher Syndrome, Type 1 6 | 7
cystic fibrosis 6 | 1,670
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,289
lung cancer 6 | 4,473
non-small cell lung cancer 6 | 2,798
pediatric high grade glioma 6 | 2,712
Usher syndrome type 2 5 | 5
lung adenocarcinoma 5 | 2,714
pancreatic cancer 5 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
posterior fossa group A ependymoma 5 | 1,511
spina bifida 5 | 1,064
subependymal giant cell astrocytoma 5 | 2,287
ulcerative colitis 5 | 2,087
Usher Syndrome, Type II 4 | 4
acute quadriplegic myopathy 4 | 1,157
aldosterone-producing adenoma 4 | 664
breast carcinoma 4 | 1,614
ductal carcinoma in situ 4 | 1,745
esophageal adenocarcinoma 4 | 737
gastric carcinoma 4 | 832
group 3 medulloblastoma 4 | 2,254
medulloblastoma 4 | 1,524
posterior fossa group B ependymoma 4 | 1,530
tuberculosis 4 | 1,563
Cancer 3 | 2,346
Leber congenital amaurosis 3 | 72
Rheumatoid Arthritis 3 | 1,170
adrenocortical carcinoma 3 | 1,427
astrocytoma 3 | 1,493
atypical teratoid/rhabdoid tumor 3 | 1,095
dermatomyositis 3 | 966
nasopharyngeal carcinoma 3 | 1,056
Atopic dermatitis 2 | 944
Deafness 2 | 18
Deafness, Autosomal Recessive 12 2 | 2
Down syndrome 2 | 548
Dyslexia 2 | 36
Endometriosis 2 | 535
Gaucher disease type 3 2 | 76
Male infertility 2 | 170
Substance-Related Disorders 2 | 114
USHER SYNDROME, TYPE ID 2 | 2
USHER SYNDROME, TYPE IIA 2 | 2
USHER SYNDROME, TYPE IIC, GPR98/PDZD7, DIGENIC 2 | 2
Usher syndrome 1D/F 2 | 2
Usher syndrome 2C 2 | 2
Usher syndrome type 1D 2 | 2
Usher syndrome type 2C 2 | 2
Usher syndrome, type 1D 2 | 2
Usher syndrome, type 2A 2 | 2
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
autosomal recessive nonsyndromic deafness 12 2 | 3
colon cancer 2 | 1,475
cone-rod dystrophy 2 | 60
cutaneous lupus erythematosus 2 | 1,056
juvenile dermatomyositis 2 | 1,189
mucosa-associated lymphoid tissue lymphoma 2 | 480
non primary Sjogren syndrome sicca 2 | 840
primary pancreatic ductal adenocarcinoma 2 | 1,271
DEAFNESS, AUTOSOMAL RECESSIVE 98 1 | 1
Deafness, autosomal recessive 104 1 | 1
Deafness, autosomal recessive, 104 1 | 1
Deafness, autosomal recessive, 2 1 | 1
Deafness, autosomal recessive, 98 1 | 1
Juvenile xanthogranuloma 1 | 6
Monkeypox 1 | 10
Stargardt disease 1 | 7
Usher syndrome 1B 1 | 1
autosomal recessive nonsyndromic deafness 98 1 | 1

Tissue

Digestive Tract 50 | 18,472
Endocrine System 50 | 18,511
Female tissues 50 | 18,646
Nervous System 50 | 18,560
Urinary Tract 50 | 18,443
Liver and Pancreas 49 | 18,135
Skin and soft tissues 49 | 18,114
Blood and immune system 47 | 17,994
Cardiovascular System 47 | 17,957
Male tissues 46 | 17,968
Respiratory system 44 | 17,483

Target Family

Non-IDG 34 | 11,969
Enzyme 5 | 4,146
Transcription Factor 4 | 1,400
Transporter 3 | 473
Ion Channel 2 | 341
Kinase 2 | 634
GPCR 1 | 408

Compartment GO Term

Stereocilium 51 | 51
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phosphatidylinositol phosphatase PTPRQ PTPRQ Tbio Enzyme -1.02216 10.5 0
Forkhead box protein S1 FOXS1 Tdark Transcription Factor -0.35439 3.87 45
Unconventional myosin-VI MYO6 Tbio Non-IDG -1.66390 49.9 93
Taperin TPRN Tbio Non-IDG -0.71336 6.12 29
Plasma membrane calcium-transporting ATPase 2 ATP2B2 Tbio Transporter -2.06568 116.3 74
Cadherin-23 CDH23 Tbio Non-IDG -1.98033 103.4 181
Usherin USH2A Tbio Non-IDG -2.42386 261.0 34
TRIO and F-actin-binding protein TRIOBP Tbio Non-IDG -1.01390 10.4 72
Clarin-1 CLRN1 Tbio Non-IDG -1.39328 47.8 23
Myosin-IIIa MYO3A Tbio Kinase -1.24670 20.2 127