Development Level

Tbio 25 | 11,445
Tdark 6 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 7 | 979
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal neural tube morpholog... 1 | 12
decreased bone mineral density 1 | 126
decreased circulating glucose ... 1 | 126
decreased grip strength 1 | 116
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased vertical activity 1 | 208
enlarged heart 1 | 210
hypoactivity 1 | 132
impaired righting response 1 | 26
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased total body fat amoun... 1 | 134
thrombocytosis 1 | 27

Disease

ovarian cancer 24 | 8,520
lung cancer 15 | 4,740
group 3 medulloblastoma 14 | 4,104
Carcinoma 12 | 11,493
osteosarcoma 12 | 7,950
diabetes mellitus 11 | 1,728
glioblastoma 11 | 5,792
medulloblastoma, large-cell 11 | 6,241
psoriasis 11 | 6,694
Multiple myeloma 10 | 1,332
Conductive hearing loss 9 | 123
Intellectual disability 9 | 1,016
malignant mesothelioma 9 | 3,232
Dull intelligence 8 | 645
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
atypical teratoid / rhabdoid tumor 8 | 5,112
ependymoma 8 | 4,679
oligodendroglioma 8 | 2,850
Anteverted nostril 7 | 191
dermatomyositis 7 | 966
Abnormality of retinal pigmentation 6 | 111
Abnormality of the retinal vasculature 6 | 59
Atypical scarring of skin 6 | 62
Blind Vision 6 | 111
Blindness, Legal 6 | 110
Broad flat nasal bridge 6 | 236
Cataract 6 | 297
Congenital anomaly of testis 6 | 52
Congenital hypoplasia of penis 6 | 176
Electroretinogram abnormal 6 | 95
Glaucoma 6 | 239
Hyperinsulinism 6 | 133
Hypogonadism 6 | 173
Keratoconus 6 | 113
Lens Opacities 6 | 231
Nasal bridge wide 6 | 236
Night blindness, progressive 6 | 51
Nystagmus 6 | 317
Obesity 6 | 678
Ophthalmoplegia 6 | 106
Optic Atrophy 6 | 242
Photodysphoria 6 | 121
Photophobia 6 | 121
Retinal pigment epithelial abnormality 6 | 111
Retinitis Pigmentosa 6 | 226
Sensorineural Hearing Loss (disorder) 6 | 284
acute myeloid leukemia 6 | 783
adult high grade glioma 6 | 3,801
astrocytoma 6 | 1,146
Difficulties with night vision 5 | 87
Night Blindness 5 | 101
Kidney cancer 4 | 2,613
Waldenstrons macroglobulinemia 4 | 765
Autosomal recessive predisposition 3 | 1,442
Cleft Palate 3 | 271
Crohn's disease 3 | 321
Hypoplastic mandible condyle 3 | 275
Mandibular hypoplasia 3 | 275
Micrognathism 3 | 275
Retinitis pigmentosa 11 3 | 59
Retinitis pigmentosa 13 3 | 11
Uranostaphyloschisis 3 | 167
astrocytic glioma 3 | 2,597
breast carcinoma 3 | 1,638
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
primitive neuroectodermal tumor 3 | 3,035
Absent auditory canals 2 | 23
Absent external auditory canals 2 | 23
Atresia of the external auditory canal 2 | 23
Atretic auditory canal 2 | 23
Atrial Septal Defects 2 | 85
Congenital Epicanthus 2 | 177
Epilepsy 2 | 792
Feeding difficulties 2 | 127
Feeding difficulties in infancy 2 | 175
Gaucher disease type 1 2 | 180
HIV Infections 2 | 102
Low Vision 2 | 174
Low set ears 2 | 181
Pneumonia 2 | 174
Polycystic ovary syndrome 2 | 360
Retinal Degeneration 2 | 106
Rheumatoid arthritis 2 | 1,191
Short stature 2 | 531
Small head 2 | 374
Ventricular Septal Defects 2 | 119
Visual Impairment 2 | 174
adrenocortical carcinoma 2 | 1,428
glioblastoma multiforme 2 | 142
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
sonic hedgehog group medulloblastoma 2 | 467
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010

Tissue

Blood and immune system 31 | 16,909
Cardiovascular System 31 | 15,192
Digestive Tract 31 | 17,369
Endocrine System 31 | 18,159
Female tissues 31 | 17,400
Liver and Pancreas 31 | 16,750
Male tissues 31 | 17,142
Nervous System 31 | 16,725
Respiratory system 31 | 16,393
Skin and soft tissues 31 | 17,230
Urinary Tract 31 | 16,678

Target Family

Non-IDG 28 | 12,091
Enzyme 4 | 4,145

Compartment GO Term

Spliceosomal tri-snRNP complex 32 | 32
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,237 | 12,237
Intracellular organelle 12,023 | 12,023
membrane-bounded organelle 11,130 | 11,130
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,340 | 10,340
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,561 | 7,561
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,972 | 3,972
non-membrane-bounded organelle 3,972 | 3,972
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,955 | 1,955
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,547 | 1,547
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,123 | 1,123
Nuclear outer membrane-endopla... 1,121 | 1,121
Nucleoplasm part 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,040 | 1,040
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 949 | 949
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 848 | 848
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pre-mRNA-splicing factor 18 PRPF18 Tbio Non-IDG -1.36183 19.8 84
U6 snRNA-associated Sm-like protein LSm2 LSM2 Tbio Non-IDG -1.40226 23.0 121
U6 snRNA-associated Sm-like protein LSm8 LSM8 Tdark Non-IDG -0.82004 6.23 34
U6 snRNA-associated Sm-like protein LSm4 LSM4 Tbio Non-IDG -2.13782 132.0 149
U4/U6.U5 tri-snRNP-associated protein 1 SART1 Tbio Non-IDG -1.82978 70.5 140
Peptidyl-prolyl cis-trans isomerase H PPIH Tbio Enzyme -1.36230 23.3 88
Small nuclear ribonucleoprotein G SNRPG Tdark Non-IDG 0.12 1.33 104
Small nuclear ribonucleoprotein Sm D2 SNRPD2 Tbio Non-IDG -1.68245 44.9 118
Small nuclear ribonucleoprotein Sm D3 SNRPD3 Tbio Non-IDG -1.64561 38.0 165
Small nuclear ribonucleoprotein Sm D1 SNRPD1 Tbio Non-IDG -2.41573 241.5 105