Development Level

Tbio 163 | 11,445
Tdark 38 | 6,588
Tchem 11 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 28 | 979
embryonic lethality prior to o... 10 | 239
embryonic lethality prior to t... 6 | 278
abnormal behavior 5 | 298
abnormal bone structure 4 | 187
decreased leukocyte cell numbe... 3 | 73
hypoactivity 3 | 132
increased lean body mass 3 | 172
increased mean corpuscular vol... 3 | 92
abnormal embryo size 2 | 220
decreased bone mineral density 2 | 126
decreased circulating glucose ... 2 | 126
decreased hemoglobin content 2 | 68
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular hem... 2 | 50
decreased mean corpuscular hem... 2 | 31
decreased neutrophil cell numb... 2 | 42
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
enlarged heart 2 | 210
impaired glucose tolerance 2 | 75
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
increased fasted circulating g... 2 | 76
increased lymphocyte cell numb... 2 | 32
increased mean platelet volume 2 | 45
increased total body fat amoun... 2 | 134
male infertility 2 | 123
prenatal lethality prior to he... 2 | 87
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal chorioallantoic fusio... 1 | 8
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal embryo turning 1 | 31
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal pancreas morphology 1 | 13
abnormal placenta size 1 | 20
abnormal retinal vasculature m... 1 | 27
absent pinna reflex 1 | 23
cardiovascular system phenotyp... 1 | 36
corneal opacity 1 | 32
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating phosphat... 1 | 27
decreased circulating potassiu... 1 | 20
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
decreased startle reflex 1 | 75
decreased urine magnesium leve... 1 | 3
hyperactivity 1 | 148
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased blood uric acid leve... 1 | 5
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating free fat... 1 | 20
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased grip strength 1 | 41
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
pale yolk sac 1 | 25
pallor 1 | 34
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
small superior vagus ganglion 1 | 74
thrombocytosis 1 | 27
vertebral fusion 1 | 23

Disease

Carcinoma 141 | 11,493
ovarian cancer 138 | 8,520
osteosarcoma 93 | 7,950
medulloblastoma, large-cell 77 | 6,241
group 3 medulloblastoma 74 | 4,104
psoriasis 69 | 6,694
glioblastoma 66 | 5,792
lung cancer 62 | 4,740
Multiple myeloma 51 | 1,332
atypical teratoid / rhabdoid tumor 45 | 5,112
ependymoma 45 | 4,679
malignant mesothelioma 44 | 3,232
oligodendroglioma 40 | 2,850
Breast cancer 35 | 3,578
acute quadriplegic myopathy 35 | 1,158
primitive neuroectodermal tumor 35 | 3,035
dermatomyositis 33 | 966
intraductal papillary-mucinous carcinoma (IPMC) 33 | 2,989
Kidney cancer 31 | 2,613
diabetes mellitus 31 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 30 | 2,955
Waldenstrons macroglobulinemia 29 | 765
Pick disease 28 | 1,894
astrocytoma 28 | 1,146
adult high grade glioma 27 | 3,801
astrocytic glioma 26 | 2,597
Cancer 22 | 2,499
Intellectual disability 22 | 1,016
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
progressive supranuclear palsy 22 | 676
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,962
invasive ductal carcinoma 19 | 2,951
lung adenocarcinoma 19 | 2,716
juvenile dermatomyositis 18 | 1,187
non-small cell lung cancer 18 | 2,890
subependymal giant cell astrocytoma 17 | 2,287
Amyotrophic lateral sclerosis 15 | 451
Dull intelligence 15 | 645
Low intelligence 15 | 645
Mental Retardation 15 | 645
Mental deficiency 15 | 645
Poor school performance 15 | 645
Muscular atrophy 14 | 71
pancreatic cancer 14 | 2,398
pediatric high grade glioma 14 | 1,064
acute myeloid leukemia 13 | 783
tuberculosis and treatment for 6 months 12 | 409
Astrocytoma, Pilocytic 11 | 3,081
Conductive hearing loss 10 | 123
Spinal muscular atrophy 10 | 34
breast carcinoma 10 | 1,638
group 4 medulloblastoma 10 | 1,855
non primary Sjogren syndrome sicca 10 | 891
pituitary cancer 10 | 1,972
Autosomal recessive predisposition 9 | 1,442
Retinitis Pigmentosa 9 | 226
Rheumatoid arthritis 9 | 1,191
atypical teratoid/rhabdoid tumor 9 | 357
spina bifida 9 | 1,074
Anteverted nostril 8 | 191
colon cancer 8 | 1,478
hepatocellular carcinoma 8 | 547
nasopharyngeal carcinoma 8 | 1,058
Abnormality of the retinal vasculature 7 | 59
Broad flat nasal bridge 7 | 236
Cataract 7 | 297
Congenital hypoplasia of penis 7 | 176
Epilepsy 7 | 792
Frontotemporal dementia 7 | 51
Gaucher disease type 1 7 | 180
Glaucoma 7 | 239
Hypogonadism 7 | 173
Keratoconus 7 | 113
Lens Opacities 7 | 231
Nasal bridge wide 7 | 236
Obesity 7 | 678
Sensorineural Hearing Loss (disorder) 7 | 284
Short stature 7 | 531
Small head 7 | 374
Abnormality of retinal pigmentation 6 | 111
Blind Vision 6 | 111
Blindness, Legal 6 | 110
Cleft Palate 6 | 271
Down syndrome 6 | 499
Electroretinogram abnormal 6 | 95
HIV Infections 6 | 102
Hyperinsulinism 6 | 133
Microcephaly 6 | 166
Nystagmus 6 | 317
Ophthalmoplegia 6 | 106
Optic Atrophy 6 | 242
Photophobia 6 | 121
Retinal pigment epithelial abnormality 6 | 111
Schizophrenia 6 | 1,160
Uranostaphyloschisis 6 | 167
adrenocortical carcinoma 6 | 1,428
cutaneous lupus erythematosus 6 | 1,057
pancreatic carcinoma 6 | 562
sonic hedgehog group medulloblastoma 6 | 467
tuberculosis 6 | 2,010

Tissue

Endocrine System 211 | 18,159
Digestive Tract 209 | 17,369
Female tissues 209 | 17,400
Liver and Pancreas 209 | 16,750
Nervous System 209 | 16,725
Skin and soft tissues 209 | 17,230
Urinary Tract 209 | 16,678
Blood and immune system 208 | 16,909
Male tissues 208 | 17,142
Respiratory system 208 | 16,393
Cardiovascular System 206 | 15,192

Target Family

Non-IDG 165 | 12,091
Enzyme 36 | 4,145
Epigenetic 5 | 242
Kinase 3 | 634
Transcription Factor 2 | 1,400
GPCR 1 | 408

Compartment GO Term

Spliceosomal complex 212 | 212
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
NACHT domain- and WD repeat-containing protein 1 NWD1 Tdark Non-IDG 0.08 1.22 3
Probable ATP-dependent RNA helicase DDX5 DDX5 Tbio Enzyme -2.08566 121.1 344
RNA-binding protein 8A RBM8A Tbio Non-IDG -3.16448 1415.1 94
RNA-binding protein Raly RALY Tbio Non-IDG -1.12263 14.4 176
Pre-mRNA-splicing factor CWC25 homolog CWC25 Tdark Non-IDG -0.71222 5.53 18
Telomerase protein component 1 TEP1 Tbio Enzyme -1.74492 50.6 71
U6 snRNA-associated Sm-like protein LSm4 LSM4 Tbio Non-IDG -2.13782 132.0 149
Pre-mRNA-splicing factor RBM22 RBM22 Tbio Non-IDG -0.84549 7.65 130
Heterogeneous nuclear ribonucleoprotein M HNRNPM Tbio Non-IDG -1.64443 45.9 331
G patch domain-containing protein 1 GPATCH1 Tdark Non-IDG 0.54 0.26 14