Development Level

Tbio 120 | 11,445
Tchem 21 | 1,598
Tdark 17 | 6,588

Collection

Kinase: IDG Consortium (Target... 2 | 125
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 17 | 979
preweaning lethality, incomple... 10 | 499
abnormal bone structure 5 | 187
embryonic lethality prior to o... 5 | 239
impaired glucose tolerance 5 | 75
abnormal embryo size 4 | 220
cataract 4 | 92
decreased circulating glucose ... 4 | 126
decreased total body fat amoun... 4 | 207
embryonic lethality prior to t... 4 | 278
increased mean corpuscular hem... 4 | 96
increased mean corpuscular vol... 4 | 92
increased total body fat amoun... 4 | 134
abnormal lens morphology 3 | 81
decreased body weight 3 | 161
decreased bone mineral content 3 | 151
decreased circulating choleste... 3 | 93
decreased lean body mass 3 | 135
increased blood urea nitrogen ... 3 | 48
increased bone mineral content 3 | 108
increased circulating creatini... 3 | 38
increased fasted circulating g... 3 | 76
increased lean body mass 3 | 172
increased leukocyte cell numbe... 3 | 47
increased mean platelet volume 3 | 45
male infertility 3 | 123
abnormal cranium morphology 2 | 36
abnormal embryo turning 2 | 31
abnormal head morphology 2 | 10
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
abnormal skin coloration 2 | 25
cardiovascular system phenotyp... 2 | 36
decreased body length 2 | 101
decreased bone mineral density 2 | 126
decreased caudal vertebrae num... 2 | 53
decreased circulating serum al... 2 | 82
decreased mean corpuscular vol... 2 | 79
decreased startle reflex 2 | 75
embryonic growth retardation 2 | 106
enlarged lymph nodes 2 | 37
female infertility 2 | 60
increased bone mineral density 2 | 72
increased startle reflex 2 | 112
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
thrombocytopenia 2 | 56
thrombocytosis 2 | 27
abnormal body wall morphology 1 | 9
abnormal coat-hair pigmentatio... 1 | 64
abnormal epididymis morphology 1 | 42
abnormal liver morphology 1 | 17
abnormal locomotor behavior 1 | 24
abnormal lung morphology 1 | 26
abnormal pancreas morphology 1 | 13
abnormal pelvic girdle bone mo... 1 | 12
abnormal retinal inner nuclear... 1 | 8
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
convulsive seizures 1 | 13
corneal opacity 1 | 32
decreased circulating HDL chol... 1 | 68
decreased circulating creatini... 1 | 39
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased heart left ventricle... 1 | 28
decreased hemoglobin content 1 | 68
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
enlarged epididymis 1 | 31
enlarged spleen 1 | 41
enlarged testis 1 | 6
hypoactivity 1 | 132
impaired righting response 1 | 26
increased anti-nuclear antigen... 1 | 19
increased body length 1 | 32
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased circulating thyroxin... 1 | 7
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased or absent threshold ... 1 | 101
mammalian phenotype 1 | 17
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
shortened RR interval 1 | 17
small testis 1 | 58
urinary bladder obstruction 1 | 4
vertebral fusion 1 | 23

Disease

Carcinoma 111 | 11,493
ovarian cancer 91 | 8,520
medulloblastoma, large-cell 83 | 6,241
osteosarcoma 76 | 7,950
psoriasis 76 | 6,694
group 3 medulloblastoma 72 | 4,104
lung cancer 66 | 4,740
glioblastoma 64 | 5,792
atypical teratoid / rhabdoid tumor 62 | 5,112
Breast cancer 61 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 56 | 3,291
primitive neuroectodermal tumor 54 | 3,035
malignant mesothelioma 52 | 3,232
non-small cell lung cancer 52 | 2,890
ependymoma 47 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 47 | 2,989
Cancer 45 | 2,499
adult high grade glioma 45 | 3,801
adrenocortical carcinoma 44 | 1,428
lung adenocarcinoma 40 | 2,716
invasive ductal carcinoma 36 | 2,951
Kidney cancer 35 | 2,613
oligodendroglioma 31 | 2,850
colon cancer 30 | 1,478
ductal carcinoma in situ 30 | 1,745
pancreatic cancer 30 | 2,398
Atopic dermatitis 29 | 952
nasopharyngeal carcinoma 29 | 1,058
Endometriosis 28 | 540
Intellectual disability 28 | 1,016
breast carcinoma 26 | 1,638
interstitial cystitis 23 | 2,312
Astrocytoma, Pilocytic 21 | 3,081
Microcephaly 20 | 166
astrocytic glioma 20 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
Small head 19 | 374
Autosomal recessive predisposition 18 | 1,442
Cognitive delay 17 | 608
Global developmental delay 17 | 608
Mental and motor retardation 17 | 608
Pick disease 17 | 1,894
Dull intelligence 16 | 645
Low intelligence 16 | 645
Mental Retardation 16 | 645
Mental deficiency 16 | 645
Poor school performance 16 | 645
ulcerative colitis 16 | 1,819
primary Sjogren syndrome 15 | 735
subependymal giant cell astrocytoma 15 | 2,287
pituitary cancer 14 | 1,972
Short stature 12 | 531
active Crohn's disease 12 | 922
acute quadriplegic myopathy 12 | 1,158
dermatomyositis 12 | 966
group 4 medulloblastoma 12 | 1,855
tuberculosis 12 | 2,010
Multiple myeloma 11 | 1,332
astrocytoma 11 | 1,146
diabetes mellitus 11 | 1,728
lung carcinoma 11 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
pediatric high grade glioma 11 | 1,064
Hypoplastic mandible condyle 10 | 275
Liver cancer 10 | 604
Mandibular hypoplasia 10 | 275
Micrognathism 10 | 275
Rheumatoid arthritis 10 | 1,191
Waldenstrons macroglobulinemia 10 | 765
aldosterone-producing adenoma 10 | 665
chronic rhinosinusitis 10 | 512
Cataract 9 | 297
Epilepsy 9 | 792
Fetal Growth Retardation 9 | 189
Infant, Small for Gestational Age 9 | 176
Intrauterine retardation 9 | 176
tuberculosis and treatment for 6 months 9 | 409
Lens Opacities 8 | 231
Schizophrenia 8 | 1,160
esophageal adenocarcinoma 8 | 737
juvenile dermatomyositis 8 | 1,187
non primary Sjogren syndrome sicca 8 | 891
posterior fossa group A ependymoma 8 | 468
progressive supranuclear palsy 8 | 676
spina bifida 8 | 1,074
Ciliopathy 7 | 71
Delayed bone age 7 | 136
Glaucoma 7 | 239
Microcephalic osteodysplastic primordial dwarfism type II 7 | 13
cystic fibrosis 7 | 1,696
posterior fossa group B ependymoma 7 | 416
Anteverted nostril 6 | 191
Bipolar Disorder 6 | 666
Congenital hypoplasia of penis 6 | 176
Nystagmus 6 | 317
Obesity 6 | 678
Retinitis Pigmentosa 6 | 226
Seizures 6 | 596
Sloping forehead 6 | 46
pancreatic carcinoma 6 | 562

Tissue

Endocrine System 154 | 18,159
Digestive Tract 153 | 17,369
Male tissues 153 | 17,142
Urinary Tract 153 | 16,678
Female tissues 152 | 17,400
Liver and Pancreas 152 | 16,750
Nervous System 152 | 16,725
Skin and soft tissues 152 | 17,230
Blood and immune system 151 | 16,909
Respiratory system 151 | 16,393
Cardiovascular System 147 | 15,192

Target Family

Non-IDG 117 | 12,091
Enzyme 24 | 4,145
Kinase 15 | 634
Transcription Factor 1 | 1,400
oGPCR 1 | 421

Compartment GO Term

Spindle pole 158 | 158
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transforming acidic coiled-coil-containing protein 3 TACC3 Tbio Non-IDG -1.99617 101.2 222
Nuclear distribution protein nudE homolog 1 NDE1 Tbio Non-IDG -2.01711 96.0 192
Mitotic spindle assembly checkpoint protein MAD1 MAD1L1 Tbio Non-IDG -1.17500 13.6 283
Dual specificity protein phosphatase CDC14C CDC14C Tdark Enzyme -0.37414 4.05 0
Kinesin-like protein KIF20B KIF20B Tbio Non-IDG -1.04680 12.5 48
Centlein CNTLN Tbio Non-IDG -2.28518 122.3 76
Sperm-associated antigen 5 SPAG5 Tbio Non-IDG -1.72743 51.4 136
Kelch-like protein 21 KLHL21 Tbio Non-IDG -0.32074 2.17 65
BAG family molecular chaperone regulator 1 BAG1 Tbio Non-IDG -2.50252 335.1 394
Nuclear mitotic apparatus protein 1 NUMA1 Tbio Non-IDG -2.76544 575.8 235