Development Level

Tbio 32 | 11,651
Tchem 8 | 1,388
Tdark 3 | 6,593

IMPC Phenotype

preweaning lethality, complete... 4 | 979
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
preweaning lethality, incomple... 3 | 499
decreased circulating serum al... 2 | 82
increased circulating alkaline... 2 | 122
increased fasted circulating g... 2 | 76
increased mean corpuscular vol... 2 | 92
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal liver morphology 1 | 17
abnormal retina morphology 1 | 71
cataract 1 | 92
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating chloride... 1 | 30
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
decreased spleen weight 1 | 10
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged kidney 1 | 14
hypoactivity 1 | 132
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating chloride... 1 | 41
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
sclerocornea 1 | 2
short tibia 1 | 97
tremors 1 | 39

Disease

Carcinoma 31 | 11,493
ovarian cancer 29 | 8,520
medulloblastoma, large-cell 28 | 6,241
Breast cancer 26 | 3,578
group 3 medulloblastoma 24 | 4,104
atypical teratoid / rhabdoid tumor 23 | 5,112
lung cancer 23 | 4,740
psoriasis 23 | 6,694
glioblastoma 22 | 5,792
invasive ductal carcinoma 21 | 2,951
non-small cell lung cancer 21 | 2,890
adrenocortical carcinoma 20 | 1,428
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,291
pancreatic cancer 20 | 2,398
primitive neuroectodermal tumor 18 | 3,035
Endometriosis 17 | 540
lung adenocarcinoma 17 | 2,716
malignant mesothelioma 17 | 3,232
adult high grade glioma 16 | 3,801
breast carcinoma 16 | 1,638
ependymoma 16 | 4,679
Atopic dermatitis 15 | 952
Cancer 15 | 2,499
colon cancer 14 | 1,478
ductal carcinoma in situ 14 | 1,745
osteosarcoma 14 | 7,950
ulcerative colitis 14 | 1,819
nasopharyngeal carcinoma 13 | 1,058
Kidney cancer 12 | 2,613
Astrocytoma, Pilocytic 9 | 3,081
oligodendroglioma 9 | 2,850
interstitial cystitis 8 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
Autosomal recessive predisposition 7 | 1,442
Intellectual disability 7 | 1,016
tuberculosis 7 | 2,010
Fetal Growth Retardation 5 | 189
Hypoplastic mandible condyle 5 | 275
Infant, Small for Gestational Age 5 | 176
Intrauterine retardation 5 | 176
Mandibular hypoplasia 5 | 275
Micrognathism 5 | 275
Small head 5 | 374
active Crohn's disease 5 | 922
astrocytic glioma 5 | 2,597
cystic fibrosis 5 | 1,696
lung carcinoma 5 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pituitary cancer 5 | 1,972
subependymal giant cell astrocytoma 5 | 2,287
Cerebellar Hypoplasia 4 | 61
Dull intelligence 4 | 645
Liver Cirrhosis, Experimental 4 | 769
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Multiple myeloma 4 | 1,332
Pick disease 4 | 1,894
Poor school performance 4 | 645
Waldenstrons macroglobulinemia 4 | 765
acute quadriplegic myopathy 4 | 1,158
chronic rhinosinusitis 4 | 512
gastric cancer 4 | 459
group 4 medulloblastoma 4 | 1,855
hepatocellular carcinoma 4 | 547
primary Sjogren syndrome 4 | 735
spina bifida 4 | 1,074
Agenesis of corpus callosum 3 | 83
Cognitive delay 3 | 608
Epilepsy 3 | 792
Global developmental delay 3 | 608
Liver cancer 3 | 604
Low set ears 3 | 181
Mental and motor retardation 3 | 608
Microcephaly 3 | 166
Polycystic ovary syndrome 3 | 360
Renal Cell Carcinoma 3 | 214
Rheumatoid arthritis 3 | 1,191
Short stature 3 | 531
Stomach Neoplasms 3 | 300
acute myeloid leukemia 3 | 783
astrocytoma 3 | 1,146
cystic fibrosis and chronic rhinosinusitis 3 | 214
esophageal adenocarcinoma 3 | 737
gastric carcinoma 3 | 807
pancreatic carcinoma 3 | 562
pediatric high grade glioma 3 | 1,064
posterior fossa group A ependymoma 3 | 468
primary pancreatic ductal adenocarcinoma 3 | 1,109
Abnormally small eyeball 2 | 97
Decreased size of eyeball 2 | 97
Glaucoma 2 | 239
Maternal oligohydramnios 2 | 31
Schizophrenia 2 | 1,160
Uranostaphyloschisis 2 | 167
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
periodontitis 2 | 293
sonic hedgehog group medulloblastoma 2 | 467

Tissue

Digestive Tract 43 | 17,369
Endocrine System 43 | 18,159
Blood and immune system 42 | 16,909
Female tissues 42 | 17,400
Urinary Tract 42 | 16,678
Liver and Pancreas 41 | 16,750
Male tissues 41 | 17,142
Nervous System 41 | 16,725
Respiratory system 41 | 16,393
Skin and soft tissues 41 | 17,230
Cardiovascular System 40 | 15,192

Target Family

Non-IDG 27 | 12,091
Enzyme 9 | 4,145
Kinase 6 | 634
oGPCR 1 | 421

Compartment GO Term

Spindle midzone 43 | 43
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pleckstrin homology domain-containing family G member 6 PLEKHG6 Tbio Non-IDG -0.56736 4.94 109
Cell division control protein 6 homolog CDC6 Tbio Non-IDG -2.51683 336.8 574
Dual specificity protein phosphatase CDC14A CDC14A Tbio Enzyme -2.31524 216.3 245
Borealin CDCA8 Tbio Non-IDG -1.60291 37.6 299
Serine/threonine-protein kinase PLK1 PLK1 Tchem Kinase -3.09610 1271.1 856
Protein unc-119 homolog A UNC119 Tbio Non-IDG -2.04467 109.5 42
Transforming protein RhoA RHOA Tbio Enzyme -3.54095 3332.7 501
Rac GTPase-activating protein 1 RACGAP1 Tbio Enzyme -1.69445 57.6 382
Aurora kinase C AURKC Tchem Kinase -2.00731 103.6 354
Kinesin-like protein KIF14 KIF14 Tbio Non-IDG -1.46037 34.0 93