Development Level

Tbio 60 | 11,445
Tchem 13 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 13 | 979
embryonic lethality prior to o... 4 | 239
cataract 3 | 92
embryonic lethality prior to t... 3 | 278
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal lens morphology 2 | 81
abnormal seminal vesicle morph... 2 | 114
embryonic growth retardation 2 | 106
increased circulating HDL chol... 2 | 80
increased circulating creatini... 2 | 38
increased fasted circulating g... 2 | 76
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal embryo turning 1 | 31
abnormal motor learning 1 | 3
abnormal placenta morphology 1 | 5
abnormal placenta size 1 | 20
abnormal placenta vasculature 1 | 2
abnormal retinal inner nuclear... 1 | 8
abnormal skin coloration 1 | 25
abnormal tail morphology 1 | 25
cardiovascular system phenotyp... 1 | 36
convulsive seizures 1 | 13
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased coping response 1 | 8
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased heart left ventricle... 1 | 28
decreased total body fat amoun... 1 | 207
edema 1 | 59
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating glucose ... 1 | 24
increased circulating sodium l... 1 | 71
increased grip strength 1 | 41
increased heart rate 1 | 23
increased lean body mass 1 | 172
increased mean platelet volume 1 | 45
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
sclerocornea 1 | 2
shortened RR interval 1 | 17
small kidney 1 | 16
small spleen 1 | 19
small testis 1 | 58
syndactyly 1 | 23
thrombocytopenia 1 | 56

Disease

Carcinoma 53 | 11,493
ovarian cancer 51 | 8,520
medulloblastoma, large-cell 49 | 6,241
psoriasis 49 | 6,694
glioblastoma 44 | 5,792
Breast cancer 43 | 3,578
lung cancer 42 | 4,740
group 3 medulloblastoma 41 | 4,104
atypical teratoid / rhabdoid tumor 40 | 5,112
adult high grade glioma 37 | 3,801
non-small cell lung cancer 36 | 2,890
primitive neuroectodermal tumor 36 | 3,035
adrenocortical carcinoma 34 | 1,428
invasive ductal carcinoma 34 | 2,951
osteosarcoma 34 | 7,950
intraductal papillary-mucinous carcinoma (IPMC) 33 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 33 | 3,291
malignant mesothelioma 31 | 3,232
lung adenocarcinoma 30 | 2,716
Atopic dermatitis 27 | 952
Endometriosis 27 | 540
ependymoma 27 | 4,679
breast carcinoma 26 | 1,638
ductal carcinoma in situ 25 | 1,745
Cancer 24 | 2,499
nasopharyngeal carcinoma 22 | 1,058
pancreatic cancer 22 | 2,398
colon cancer 21 | 1,478
Kidney cancer 17 | 2,613
oligodendroglioma 17 | 2,850
ulcerative colitis 13 | 1,819
interstitial cystitis 12 | 2,312
Astrocytoma, Pilocytic 11 | 3,081
tuberculosis 11 | 2,010
Intellectual disability 10 | 1,016
primary Sjogren syndrome 10 | 735
Microcephaly 9 | 166
Pick disease 9 | 1,894
Small head 9 | 374
astrocytic glioma 9 | 2,597
pituitary cancer 9 | 1,972
Multiple myeloma 8 | 1,332
subependymal giant cell astrocytoma 8 | 2,287
Cognitive delay 7 | 608
Dull intelligence 7 | 645
Global developmental delay 7 | 608
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental and motor retardation 7 | 608
Mental deficiency 7 | 645
Poor school performance 7 | 645
active Crohn's disease 7 | 922
astrocytoma 7 | 1,146
group 4 medulloblastoma 7 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
Epilepsy 6 | 792
Hypoplastic mandible condyle 6 | 275
Mandibular hypoplasia 6 | 275
Micrognathism 6 | 275
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
posterior fossa group A ependymoma 6 | 468
Autosomal recessive predisposition 5 | 1,442
Breast Neoplasms 5 | 445
Congenital Epicanthus 5 | 177
Glaucoma 5 | 239
Mammary Neoplasms 5 | 425
Renal Cell Carcinoma 5 | 214
Schizophrenia 5 | 1,160
Seizures 5 | 596
Short stature 5 | 531
acute quadriplegic myopathy 5 | 1,158
Bipolar Disorder 4 | 666
Cerebellar Hypoplasia 4 | 61
Colorectal Neoplasms 4 | 243
Downward slant of palpebral fissure 4 | 158
Low set ears 4 | 181
Melanoma 4 | 711
Polyhydramnios 4 | 108
Type 2 diabetes mellitus 4 | 272
Waldenstrons macroglobulinemia 4 | 765
esophageal adenocarcinoma 4 | 737
gastric cancer 4 | 459
inflammatory breast cancer 4 | 286
lung carcinoma 4 | 2,843
pancreatic carcinoma 4 | 562
pediatric high grade glioma 4 | 1,064
Abnormally small eyeball 3 | 97
Anteverted nostril 3 | 191
Colonic Neoplasms 3 | 142
Decreased size of eyeball 3 | 97
Lissencephaly 3 | 69
Stomach Neoplasms 3 | 300
acute myeloid leukemia 3 | 783
chronic rhinosinusitis 3 | 512
cutaneous lupus erythematosus 3 | 1,057
cystic fibrosis 3 | 1,696
dermatomyositis 3 | 966
diabetes mellitus 3 | 1,728
gastric carcinoma 3 | 807
juvenile dermatomyositis 3 | 1,187

Tissue

Endocrine System 74 | 18,159
Blood and immune system 73 | 16,909
Digestive Tract 73 | 17,369
Female tissues 73 | 17,400
Liver and Pancreas 72 | 16,750
Male tissues 72 | 17,142
Respiratory system 72 | 16,393
Skin and soft tissues 72 | 17,230
Urinary Tract 72 | 16,678
Nervous System 71 | 16,725
Cardiovascular System 68 | 15,192

Target Family

Non-IDG 59 | 12,091
Kinase 8 | 634
Enzyme 5 | 4,145
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

Compartment GO Term

Spindle microtubule 74 | 74
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,237 | 12,237
Intracellular organelle 12,023 | 12,023
membrane-bounded organelle 11,130 | 11,130
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,340 | 10,340
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,561 | 7,561
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,972 | 3,972
non-membrane-bounded organelle 3,972 | 3,972
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,955 | 1,955
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,547 | 1,547
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,123 | 1,123
Nuclear outer membrane-endopla... 1,121 | 1,121
Nucleoplasm part 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,040 | 1,040
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 949 | 949
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 848 | 848
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Kinesin-like protein KIF11 KIF11 Tchem Non-IDG -2.61375 404.4 300
Spindle and kinetochore-associated protein 2 SKA2 Tbio Non-IDG -1.23206 10.2 108
Nuclear mitotic apparatus protein 1 NUMA1 Tbio Non-IDG -2.76544 575.8 235
Sperm-associated antigen 5 SPAG5 Tbio Non-IDG -1.72743 51.4 136
Small kinetochore-associated protein KNSTRN Tbio Non-IDG -1.28291 21.4 32
Kelch-like protein 21 KLHL21 Tbio Non-IDG -0.32074 2.17 65
Calcium and integrin-binding family member 3 CIB3 Tbio Non-IDG -1.23394 14.1 101
Poly [ADP-ribose] polymerase 4 PARP4 Tchem Enzyme -1.45503 26.0 123
Kinesin-like protein KIF18B KIF18B Tbio Non-IDG -0.83463 5.23 17
Heterogeneous nuclear ribonucleoprotein U HNRNPU Tbio Non-IDG -2.33813 207.8 169