Development Level

Tbio 231 | 10,625
Tchem 46 | 1,890
Tdark 33 | 7,003
Tclin 7 | 602

Collection

Eligible Kinase Proteins 2 | 134

IMPC Term

preweaning lethality, complete... 20 | 633
decreased body weight 5 | 174
increased mean corpuscular hem... 5 | 93
increased mean corpuscular vol... 5 | 91
preweaning lethality, incomple... 5 | 260
decreased bone mineral content 4 | 157
decreased bone mineral density 4 | 126
decreased lean body mass 4 | 195
decreased mean corpuscular vol... 4 | 50
embryonic lethality prior to o... 4 | 148
embryonic lethality prior to t... 4 | 187
increased fasted circulating g... 4 | 68
increased or absent threshold ... 4 | 128
abnormal coat/hair pigmentatio... 3 | 54
abnormal cranium morphology 3 | 32
abnormal retina morphology 3 | 100
decreased circulating glucose ... 3 | 121
decreased grip strength 3 | 123
decreased total body fat amoun... 3 | 186
improved glucose tolerance 3 | 56
increased circulating HDL chol... 3 | 63
increased circulating alkaline... 3 | 119
increased circulating choleste... 3 | 53
increased exploration in new e... 3 | 56
abnormal behavior 2 | 226
abnormal bone structure 2 | 131
abnormal head morphology 2 | 10
abnormal humerus morphology 2 | 11
decreased circulating choleste... 2 | 85
decreased circulating serum al... 2 | 79
decreased erythrocyte cell num... 2 | 43
increased blood urea nitrogen ... 2 | 44
increased bone mineral density 2 | 52
increased circulating creatini... 2 | 29
increased leukocyte cell numbe... 2 | 37
increased mean platelet volume 2 | 19
increased red blood cell distr... 2 | 21
increased thermal nociceptive ... 2 | 9
narrow eye opening 2 | 15
thrombocytopenia 2 | 46
tremors 2 | 34
abnormal body wall morphology 1 | 7
abnormal coat appearance 1 | 25
abnormal cornea morphology 1 | 24
abnormal embryo size 1 | 112
abnormal eye morphology 1 | 38
abnormal kidney morphology 1 | 30
abnormal lens morphology 1 | 73
abnormal liver morphology 1 | 5
abnormal optic disc morphology 1 | 10
abnormal skin morphology 1 | 23
abnormal snout morphology 1 | 18
abnormal startle reflex 1 | 14
abnormal testis morphology 1 | 30
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 14
absent pinna reflex 1 | 21
corneal opacity 1 | 25
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased basophil cell number 1 | 11
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased caudal vertebrae num... 1 | 49
decreased cervical vertebrae n... 1 | 12
decreased circulating chloride... 1 | 32
decreased circulating magnesiu... 1 | 11
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 34
enlarged lymph nodes 1 | 27
enlarged spleen 1 | 26
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
impaired righting response 1 | 19
increased CD4-positive NK T ce... 1 | 3
increased NK T cell number 1 | 11
increased body length 1 | 20
increased circulating amylase ... 1 | 13
increased circulating aspartat... 1 | 17
increased circulating chloride... 1 | 43
increased circulating glucose ... 1 | 16
increased circulating glycerol... 1 | 11
increased grip strength 1 | 83
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased memory-marker CD4-po... 1 | 3
increased rib number 1 | 41
limb grasping 1 | 35
prenatal lethality 1 | 16
prenatal lethality prior to he... 1 | 64
short tibia 1 | 82
small testis 1 | 37
thrombocytosis 1 | 23
urinary bladder obstruction 1 | 2
vertebral fusion 1 | 23

Disease

ovarian cancer 192 | 8,492
psoriasis 159 | 6,685
medulloblastoma, large-cell 154 | 6,234
osteosarcoma 150 | 7,933
glioblastoma 141 | 5,572
lung cancer 133 | 4,473
atypical teratoid / rhabdoid tumor 105 | 4,369
primitive neuroectodermal tumor 105 | 3,031
Breast cancer 101 | 3,099
malignant mesothelioma 100 | 3,163
intraductal papillary-mucinous neoplasm (IPMN) 95 | 3,289
non-small cell lung cancer 95 | 2,798
pediatric high grade glioma 93 | 2,712
Cancer 92 | 2,346
intraductal papillary-mucinous carcinoma (IPMC) 91 | 2,988
group 3 medulloblastoma 90 | 2,254
lung adenocarcinoma 85 | 2,714
invasive ductal carcinoma 82 | 2,950
adrenocortical carcinoma 78 | 1,427
pancreatic cancer 75 | 2,300
oligodendroglioma 66 | 2,849
ductal carcinoma in situ 61 | 1,745
colon cancer 60 | 1,475
breast carcinoma 58 | 1,614
Carcinoma 56 | 2,147
pilocytic astrocytoma 56 | 3,086
Endometriosis 54 | 535
Atopic dermatitis 53 | 944
nasopharyngeal carcinoma 52 | 1,056
subependymal giant cell astrocytoma 51 | 2,287
ulcerative colitis 51 | 2,087
posterior fossa group A ependymoma 48 | 1,511
astrocytic glioma 47 | 2,241
intraductal papillary-mucinous adenoma (IPMA) 45 | 2,956
ependymoma 44 | 2,514
Pick disease 43 | 1,893
pituitary cancer 40 | 1,972
sonic hedgehog group medulloblastoma 40 | 1,482
interstitial cystitis 38 | 2,299
IGA Glomerulonephritis 37 | 454
Multiple myeloma 37 | 1,328
posterior fossa group B ependymoma 37 | 1,530
lung carcinoma 36 | 2,844
atypical teratoid/rhabdoid tumor 35 | 1,095
diabetes mellitus 33 | 1,663
adult high grade glioma 32 | 2,148
astrocytoma 29 | 1,493
medulloblastoma 29 | 1,524
primary Sjogren syndrome 29 | 789
Waldenstrons macroglobulinemia 28 | 765
group 4 medulloblastoma 28 | 1,875
primary pancreatic ductal adenocarcinoma 28 | 1,271
acute quadriplegic myopathy 27 | 1,157
Microcephaly 26 | 149
tuberculosis 26 | 1,563
Rheumatoid Arthritis 25 | 1,171
active Crohn's disease 25 | 918
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,795
Intellectual disability 23 | 573
cystic fibrosis 22 | 1,670
dermatomyositis 22 | 967
non primary Sjogren syndrome sicca 22 | 840
Kidney disease 21 | 397
juvenile dermatomyositis 21 | 1,189
acute myeloid leukemia 19 | 785
pancreatic carcinoma 18 | 567
cutaneous lupus erythematosus 17 | 1,056
esophageal adenocarcinoma 17 | 737
hepatocellular carcinoma 17 | 550
tuberculosis and treatment for 6 months 17 | 686
Alzheimer's disease 16 | 644
gastric carcinoma 16 | 832
Mammary Neoplasms 15 | 410
Amyotrophic Lateral Sclerosis 14 | 432
Stomach Neoplasms 14 | 282
spina bifida 14 | 1,064
Prostatic Neoplasms 13 | 471
Renal Cell Carcinoma 13 | 199
Schizophrenia 13 | 503
chronic rhinosinusitis 13 | 512
progressive supranuclear palsy 13 | 674
Down syndrome 12 | 548
Vascular disease 12 | 281
aldosterone-producing adenoma 12 | 664
gastric cancer 12 | 436
non-small cell lung carcinoma 12 | 413
Adenoma 11 | 165
Duchenne muscular dystrophy 11 | 602
Hypertension 11 | 293
Lung disease 11 | 136
Neurodegenerative disease 11 | 383
hereditary spastic paraplegia 11 | 313
inflammatory breast cancer 11 | 404
Bladder Neoplasm 10 | 109
Cerebrovascular disease 10 | 231
Heart disease 10 | 279
Obesity 10 | 616
Peripheral Neuropathy 10 | 303
Polycystic Ovary Syndrome 10 | 335
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 499

Tissue

Blood and immune system 314 | 17,995
Digestive Tract 314 | 18,473
Endocrine System 314 | 18,512
Female tissues 313 | 18,647
Liver and Pancreas 313 | 18,136
Male tissues 313 | 17,969
Nervous System 313 | 18,561
Urinary Tract 313 | 18,444
Cardiovascular System 312 | 17,958
Respiratory system 311 | 17,484
Skin and soft tissues 311 | 18,115

Target Family

Non-IDG 234 | 11,969
Enzyme 43 | 4,146
Kinase 22 | 634
Transcription Factor 7 | 1,400
Epigenetic 6 | 242
Transporter 2 | 473
Ion Channel 1 | 341
Nuclear Receptor 1 | 48
oGPCR 1 | 421

Compartment GO Term

Spindle 317 | 317
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP-binding cassette sub-family A member 3 ABCA3 Tbio Transporter -2.22245 177.7 29
Small kinetochore-associated protein KNSTRN Tbio Non-IDG -1.24054 16.5 27
Cell division control protein 6 homolog CDC6 Tchem Non-IDG -2.49821 321.6 473
Ankyrin repeat domain-containing protein 53 ANKRD53 Tbio Non-IDG 0.30 0.62 79
TBCC domain-containing protein 1 TBCCD1 Tbio Non-IDG -0.36798 3.22 55
Serine/threonine-protein kinase Nek6 NEK6 Tchem Kinase -1.52648 33.8 170
Macrophage-capping protein CAPG Tbio Non-IDG -1.29740 22.4 235
BAG family molecular chaperone regulator 2 BAG2 Tbio Non-IDG -1.99998 101.1 202
Cell division cycle protein 20 homolog CDC20 Tbio Non-IDG -2.58287 383.9 269
Zinc finger protein SNAI1 SNAI1 Tbio Transcription Factor -3.23809 1522.6 484