Development Level

Tbio 36 | 11,445
Tclin 4 | 613
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
abnormal nail morphology 2 | 8
increased circulating alkaline... 2 | 122
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal digit morphology 1 | 10
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal limb position 1 | 3
abnormal seminal vesicle morph... 1 | 114
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased glycosylated hemoglo... 1 | 1
decreased lactate dehydrogenas... 1 | 16
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased startle reflex 1 | 75
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
enlarged uterus 1 | 11
hypoactivity 1 | 132
increased bone mineral density 1 | 72
increased circulating phosphat... 1 | 26
increased mean corpuscular hem... 1 | 36
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
preweaning lethality, complete... 1 | 979
short tibia 1 | 97
small superior vagus ganglion 1 | 74

Disease

Carcinoma 34 | 11,493
osteosarcoma 28 | 7,950
glioblastoma 26 | 5,792
Kidney cancer 24 | 2,613
atypical teratoid / rhabdoid tumor 23 | 5,112
ependymoma 23 | 4,679
medulloblastoma, large-cell 23 | 6,241
lung cancer 22 | 4,740
ovarian cancer 22 | 8,520
psoriasis 20 | 6,694
Astrocytoma, Pilocytic 18 | 3,081
group 3 medulloblastoma 18 | 4,104
primitive neuroectodermal tumor 18 | 3,035
adult high grade glioma 17 | 3,801
oligodendroglioma 17 | 2,850
Breast cancer 16 | 3,578
astrocytic glioma 16 | 2,597
lung adenocarcinoma 16 | 2,716
subependymal giant cell astrocytoma 16 | 2,287
malignant mesothelioma 14 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
invasive ductal carcinoma 13 | 2,951
pancreatic cancer 13 | 2,398
Liver cancer 12 | 604
lung carcinoma 12 | 2,843
Cancer 11 | 2,499
colon cancer 11 | 1,478
ductal carcinoma in situ 11 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
non-small cell lung cancer 11 | 2,890
Pick disease 10 | 1,894
diabetes mellitus 10 | 1,728
Hereditary elliptocytosis 9 | 22
Melanoma 9 | 711
acute quadriplegic myopathy 9 | 1,158
breast carcinoma 9 | 1,638
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
pituitary cancer 9 | 1,972
Anemia 8 | 365
Autosomal recessive predisposition 8 | 1,442
Endometrial cancer 8 | 311
Schizophrenia 8 | 1,160
Alzheimer's disease 7 | 658
Skin cancer 7 | 469
tuberculosis 7 | 2,010
Duchenne muscular dystrophy 6 | 601
Heart disease 6 | 306
Hypertension 6 | 396
Myopathy 6 | 185
adrenocortical carcinoma 6 | 1,428
cystic fibrosis 6 | 1,696
primary pancreatic ductal adenocarcinoma 6 | 1,109
ulcerative colitis 6 | 1,819
Anemia, Hemolytic 5 | 55
Congenital hemolytic anemia 5 | 32
Epilepsy 5 | 792
Intellectual disability 5 | 1,016
Large intestine cancer 5 | 126
Neuropathy 5 | 261
Toxic encephalopathy 5 | 141
group 4 medulloblastoma 5 | 1,855
mucosa-associated lymphoid tissue lymphoma 5 | 484
Amyotrophic lateral sclerosis 4 | 451
Anemia, hereditary spherocytic hemolytic 4 | 5
Cardiomyopathy 4 | 116
Cerebrovascular disease 4 | 238
Chronic Lymphocytic Leukemia 4 | 262
Creatine phosphokinase serum increased 4 | 110
DOID:2627 4 | 94
Down syndrome 4 | 499
Elevated creatine kinase 4 | 110
Elliptocytosis, Hereditary 4 | 9
Gaucher disease type 1 4 | 180
Hereditary spherocytosis 4 | 16
Immune system cancer 4 | 140
Liver Cirrhosis, Experimental 4 | 769
Long QT syndrome 1 4 | 20
Multiple myeloma 4 | 1,332
Muscle biopsy shows dystrophic changes 4 | 39
Muscular dystrophy 4 | 75
Osteoporosis 4 | 363
Rheumatoid arthritis 4 | 1,191
Spherocytosis 4 | 5
Status Epilepticus 4 | 98
Tetanus 4 | 68
Vascular disease 4 | 319
Waldenstrons macroglobulinemia 4 | 765
active ulcerative colitis 4 | 764
astrocytoma 4 | 1,146
dermatomyositis 4 | 966
nasopharyngeal carcinoma 4 | 1,058
nephrosclerosis 4 | 333
Atopic dermatitis 3 | 952
Polycystic ovary syndrome 3 | 360
active Crohn's disease 3 | 922
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
esophageal adenocarcinoma 3 | 737
juvenile dermatomyositis 3 | 1,187
progressive supranuclear palsy 3 | 676
spina bifida 3 | 1,074

Tissue

Blood and immune system 41 | 16,909
Endocrine System 41 | 18,159
Female tissues 41 | 17,400
Skin and soft tissues 41 | 17,230
Liver and Pancreas 40 | 16,750
Male tissues 39 | 17,142
Nervous System 39 | 16,725
Respiratory system 39 | 16,393
Cardiovascular System 38 | 15,192
Digestive Tract 38 | 17,369
Urinary Tract 38 | 16,678

Target Family

Non-IDG 35 | 12,091
Enzyme 4 | 4,145
Kinase 2 | 634

Compartment GO Term

Spectrin 41 | 41
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
Synapsin-1 SYN1 Tbio Non-IDG -2.86836 712.4 770
Ankyrin-2 ANK2 Tbio Non-IDG -2.08421 120.5 236
Spectrin beta chain, non-erythrocytic 2 SPTBN2 Tbio Non-IDG -1.73436 53.8 237
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 MACF1 Tbio Non-IDG -2.05246 115.8 45
Glycophorin-C GYPC Tbio Non-IDG -2.88194 722.9 302
Spectrin alpha chain, non-erythrocytic 1 SPTAN1 Tbio Non-IDG -2.42514 269.0 268
Spectrin alpha chain, erythrocytic 1 SPTA1 Tbio Non-IDG -2.93650 850.7 86
CD5 antigen-like CD5L Tbio Non-IDG -1.84241 70.5 357
Spectrin beta chain, erythrocytic SPTB Tbio Non-IDG -2.45982 275.1 59