Development Level

Tbio 48 | 11,445
Tchem 13 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, incomple... 5 | 499
abnormal embryo size 2 | 220
abnormal retinal vasculature m... 2 | 27
decreased vertical activity 2 | 208
preweaning lethality, complete... 2 | 979
abnormal cornea morphology 1 | 31
abnormal heart left ventricle ... 1 | 16
abnormal response to novel obj... 1 | 1
abnormal retina morphology 1 | 71
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 50
decreased circulating amylase ... 1 | 28
decreased circulating free fat... 1 | 31
decreased circulating sodium l... 1 | 22
decreased coping response 1 | 8
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased mean corpuscular hem... 1 | 31
decreased thermal nociceptive ... 1 | 2
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hydrometra 1 | 53
increased cardiac muscle contr... 1 | 8
increased circulating alkaline... 1 | 122
increased circulating creatini... 1 | 38
increased circulating free fat... 1 | 20
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased thermal nociceptive ... 1 | 9
premature death 1 | 5
prenatal lethality 1 | 28
prolonged PR interval 1 | 15
small superior vagus ganglion 1 | 74

Disease

osteosarcoma 46 | 7,950
Carcinoma 33 | 11,493
ovarian cancer 31 | 8,520
psoriasis 31 | 6,694
lung cancer 29 | 4,740
glioblastoma 27 | 5,792
interstitial cystitis 22 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
non-small cell lung cancer 20 | 2,890
Cancer 19 | 2,499
lung adenocarcinoma 19 | 2,716
Breast cancer 18 | 3,578
malignant mesothelioma 18 | 3,232
medulloblastoma, large-cell 18 | 6,241
mucosa-associated lymphoid tissue lymphoma 18 | 484
atypical teratoid / rhabdoid tumor 17 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
lung carcinoma 16 | 2,843
tuberculosis 16 | 2,010
subependymal giant cell astrocytoma 15 | 2,287
adult high grade glioma 14 | 3,801
invasive ductal carcinoma 14 | 2,951
pancreatic cancer 14 | 2,398
ulcerative colitis 14 | 1,819
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
ependymoma 12 | 4,679
pituitary cancer 12 | 1,972
Astrocytoma, Pilocytic 11 | 3,081
cystic fibrosis 11 | 1,696
diabetes mellitus 11 | 1,728
primitive neuroectodermal tumor 11 | 3,035
Arthritis 10 | 290
Multiple myeloma 10 | 1,332
group 3 medulloblastoma 10 | 4,104
Atopic dermatitis 9 | 952
Liver Cirrhosis, Experimental 9 | 769
Lung disease 9 | 142
active Crohn's disease 9 | 922
active ulcerative colitis 9 | 764
Autosomal recessive predisposition 8 | 1,442
Kidney cancer 8 | 2,613
Rheumatoid arthritis 8 | 1,191
Vascular disease 8 | 319
Waldenstrons macroglobulinemia 8 | 765
acute quadriplegic myopathy 8 | 1,158
astrocytic glioma 8 | 2,597
cutaneous lupus erythematosus 8 | 1,057
gastric carcinoma 8 | 807
Obesity 7 | 678
Schizophrenia 7 | 1,160
astrocytoma 7 | 1,146
breast carcinoma 7 | 1,638
chronic rhinosinusitis 7 | 512
ductal carcinoma in situ 7 | 1,745
esophageal adenocarcinoma 7 | 737
Chemical and Drug Induced Liver Injury 6 | 195
Inflammatory bowel disease 6 | 151
Kidney disease 6 | 430
colon cancer 6 | 1,478
nasopharyngeal carcinoma 6 | 1,058
non primary Sjogren syndrome sicca 6 | 891
oligodendroglioma 6 | 2,850
Asthma 5 | 385
Hypertension 5 | 396
Hypertensive disease 5 | 292
Intellectual disability 5 | 1,016
Liver disease 5 | 237
Melanoma 5 | 711
Splenomegaly 5 | 190
group 4 medulloblastoma 5 | 1,855
periodontitis 5 | 293
primary Sjogren syndrome 5 | 735
primary pancreatic ductal adenocarcinoma 5 | 1,109
Alzheimer's disease 4 | 658
Barrett's esophagus 4 | 182
Endometriosis 4 | 540
Epilepsy 4 | 792
Hepatomegaly 4 | 285
Kidney Diseases 4 | 114
Major Depressive Disorder 4 | 301
Pick disease 4 | 1,894
Pneumonia 4 | 174
Prostatic Neoplasms 4 | 495
Seizures 4 | 596
Unipolar Depression 4 | 250
acute myeloid leukemia 4 | 783
gastric cancer 4 | 459
head and neck cancer and chronic obstructive pulmonary disease 4 | 239
juvenile dermatomyositis 4 | 1,187
medulloblastoma 4 | 720
pediatric high grade glioma 4 | 1,064
sarcoidosis 4 | 370
spina bifida 4 | 1,074
Arthritis, Rheumatoid 3 | 174
Duchenne muscular dystrophy 3 | 601
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
dermatomyositis 3 | 966
nephrosclerosis 3 | 333
sonic hedgehog group medulloblastoma 3 | 467

Tissue

Blood and immune system 62 | 16,909
Female tissues 62 | 17,400
Liver and Pancreas 62 | 16,750
Skin and soft tissues 62 | 17,230
Digestive Tract 61 | 17,369
Urinary Tract 61 | 16,678
Endocrine System 60 | 18,159
Respiratory system 60 | 16,393
Male tissues 57 | 17,142
Cardiovascular System 56 | 15,192
Nervous System 55 | 16,725

Target Family

Non-IDG 36 | 12,091
Enzyme 23 | 4,145
Kinase 2 | 634
Transcription Factor 1 | 1,400

Compartment GO Term

Specific granule lumen 62 | 62
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pentraxin-related protein PTX3 PTX3 Tbio Non-IDG -0.80888 8.68 307
Tyrosine-protein kinase FRK FRK Tchem Kinase -1.68365 49.2 394
Folate receptor gamma FOLR3 Tbio Non-IDG -0.82047 6.26 98
Leucine-rich repeat-containing protein 7 LRRC7 Tbio Non-IDG -1.45630 31.2 41
Centrosomal protein of 290 kDa CEP290 Tbio Non-IDG -2.03755 107.9 152
Spectrin alpha chain, non-erythrocytic 1 SPTAN1 Tbio Non-IDG -2.42514 269.0 268
Armadillo repeat-containing protein 8 ARMC8 Tbio Non-IDG -1.06351 14.6 111
Cathelicidin antimicrobial peptide CAMP Tbio Non-IDG -3.31162 2089.3 0
Osteoclast-associated immunoglobulin-like receptor OSCAR Tbio Non-IDG 0.00000 169
Lysozyme C LYZ Tbio Enzyme -3.66944 4460.1 533