Development Level

Tbio 124 | 11,651
Tchem 34 | 1,388
Tclin 6 | 612
Tdark 6 | 6,593

Collection

RFA-RM-18-021 3 | 328
Ion Channel: IDG Consortium (T... 2 | 99
GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 9 | 979
preweaning lethality, incomple... 8 | 499
embryonic lethality prior to t... 6 | 278
embryonic lethality prior to o... 5 | 239
decreased total body fat amoun... 4 | 207
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
abnormal retina morphology 3 | 71
increased bone mineral density 3 | 72
increased circulating alkaline... 3 | 122
increased lean body mass 3 | 172
abnormal lens morphology 2 | 81
abnormal retinal vasculature m... 2 | 27
cataract 2 | 92
decreased circulating amylase ... 2 | 28
decreased circulating bilirubi... 2 | 19
decreased circulating insulin ... 2 | 76
decreased circulating serum al... 2 | 82
decreased vertical activity 2 | 208
enlarged lymph nodes 2 | 37
increased bone mineral content 2 | 108
increased circulating creatini... 2 | 38
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular hem... 2 | 36
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal kidney morphology 1 | 65
abnormal lung morphology 1 | 26
abnormal response to novel obj... 1 | 1
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
brachydactyly 1 | 19
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating calcium ... 1 | 36
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased coping response 1 | 8
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased mean platelet volume 1 | 25
decreased monocyte cell number 1 | 8
decreased thermal nociceptive ... 1 | 2
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged urinary bladder 1 | 8
fusion of vertebral arches 1 | 7
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased cardiac muscle contr... 1 | 8
increased circulating chloride... 1 | 41
increased circulating free fat... 1 | 20
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased heart rate variabili... 1 | 7
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased startle reflex 1 | 112
increased thermal nociceptive ... 1 | 9
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
polysyndactyly 1 | 2
premature death 1 | 5
prenatal lethality 1 | 28
prolonged PR interval 1 | 15
short tibia 1 | 97
small superior vagus ganglion 1 | 74
stereotypic behavior 1 | 3
syndactyly 1 | 23
thrombocytosis 1 | 27
trunk curl 1 | 16
vertebral transformation 1 | 12

Disease

osteosarcoma 126 | 7,950
Carcinoma 100 | 11,493
ovarian cancer 84 | 8,520
lung cancer 74 | 4,740
psoriasis 74 | 6,694
glioblastoma 73 | 5,792
medulloblastoma, large-cell 61 | 6,241
non-small cell lung cancer 57 | 2,890
interstitial cystitis 55 | 2,312
lung carcinoma 54 | 2,843
malignant mesothelioma 52 | 3,232
tuberculosis 50 | 2,010
Astrocytoma, Pilocytic 48 | 3,081
lung adenocarcinoma 48 | 2,716
Cancer 47 | 2,499
intraductal papillary-mucinous adenoma (IPMA) 47 | 2,955
atypical teratoid / rhabdoid tumor 45 | 5,112
invasive ductal carcinoma 45 | 2,951
intraductal papillary-mucinous neoplasm (IPMN) 44 | 3,291
adult high grade glioma 41 | 3,801
mucosa-associated lymphoid tissue lymphoma 41 | 484
Breast cancer 40 | 3,578
ependymoma 40 | 4,679
ulcerative colitis 40 | 1,819
intraductal papillary-mucinous carcinoma (IPMC) 38 | 2,989
pancreatic cancer 38 | 2,398
subependymal giant cell astrocytoma 36 | 2,287
pancreatic ductal adenocarcinoma liver metastasis 35 | 1,962
group 3 medulloblastoma 33 | 4,104
diabetes mellitus 31 | 1,728
cystic fibrosis 30 | 1,696
primitive neuroectodermal tumor 29 | 3,035
Rheumatoid arthritis 26 | 1,191
Liver Cirrhosis, Experimental 25 | 769
Multiple myeloma 25 | 1,332
oligodendroglioma 25 | 2,850
Waldenstrons macroglobulinemia 24 | 765
astrocytic glioma 24 | 2,597
cutaneous lupus erythematosus 24 | 1,057
pituitary cancer 23 | 1,972
Kidney cancer 22 | 2,613
astrocytoma 22 | 1,146
colon cancer 21 | 1,478
ductal carcinoma in situ 21 | 1,745
Autosomal recessive predisposition 19 | 1,442
Atopic dermatitis 18 | 952
active ulcerative colitis 18 | 764
non primary Sjogren syndrome sicca 18 | 891
Pick disease 17 | 1,894
Alzheimer's disease 16 | 658
Arthritis 16 | 290
Asthma 16 | 385
active Crohn's disease 16 | 922
acute quadriplegic myopathy 16 | 1,158
gastric carcinoma 16 | 807
group 4 medulloblastoma 16 | 1,855
nasopharyngeal carcinoma 16 | 1,058
Duchenne muscular dystrophy 15 | 601
Lung disease 15 | 142
Vascular disease 15 | 319
acute myeloid leukemia 15 | 783
breast carcinoma 15 | 1,638
dermatomyositis 15 | 966
juvenile dermatomyositis 15 | 1,187
Kidney disease 14 | 430
adrenocortical carcinoma 14 | 1,428
esophageal adenocarcinoma 14 | 737
primary Sjogren syndrome 14 | 735
Schizophrenia 13 | 1,160
pediatric high grade glioma 13 | 1,064
periodontitis 13 | 293
Anemia 12 | 365
Hypertension 12 | 396
primary pancreatic ductal adenocarcinoma 12 | 1,109
spina bifida 12 | 1,074
Melanoma 11 | 711
Obesity 11 | 678
Prostatic Neoplasms 11 | 495
gastric cancer 11 | 459
Chronic Lymphocytic Leukemia 10 | 262
Multiple Sclerosis 10 | 540
Splenomegaly 10 | 190
head and neck cancer and chronic obstructive pulmonary disease 10 | 239
hepatocellular carcinoma 10 | 547
sarcoidosis 10 | 370
Atherosclerosis 9 | 291
Chemical and Drug Induced Liver Injury 9 | 195
Crohn's disease 9 | 321
Hepatomegaly 9 | 285
Hypertensive disease 9 | 292
Inflammatory bowel disease 9 | 151
Pneumonia 9 | 174
head and neck cancer 9 | 271
Arthritis, Rheumatoid 8 | 174
Diarrhea 8 | 253
Heart disease 8 | 306
Hypereosinophilic syndrome 8 | 71
Intellectual disability 8 | 1,016
Liver disease 8 | 237
chronic rhinosinusitis 8 | 512

Tissue

Blood and immune system 169 | 16,909
Female tissues 168 | 17,400
Liver and Pancreas 168 | 16,750
Skin and soft tissues 168 | 17,230
Digestive Tract 167 | 17,369
Respiratory system 167 | 16,393
Endocrine System 166 | 18,159
Urinary Tract 166 | 16,678
Male tissues 159 | 17,142
Nervous System 155 | 16,725
Cardiovascular System 152 | 15,192

Target Family

Non-IDG 94 | 12,091
Enzyme 48 | 4,145
Ion Channel 10 | 344
Transporter 9 | 473
GPCR 4 | 408
Kinase 3 | 634
Transcription Factor 2 | 1,400

Compartment GO Term

Specific granule 170 | 170
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myeloperoxidase MPO Tchem Enzyme -3.51470 3209.3 1255
Cytoplasmic FMR1-interacting protein 1 CYFIP1 Tbio Non-IDG -1.46134 28.5 64
Cysteine-rich secretory protein 3 CRISP3 Tbio Non-IDG -1.58618 43.2 129
CCAAT/enhancer-binding protein epsilon CEBPE Tbio Transcription Factor -1.71776 57.4 246
Vesicle-associated membrane protein 8 VAMP8 Tbio Non-IDG -1.79654 64.6 107
C-type lectin domain family 5 member A CLEC5A Tbio Non-IDG -1.56055 41.9 139
EF-hand calcium-binding domain-containing protein 4B CRACR2A Tchem Non-IDG -0.52797 3.72 130
Platelet glycoprotein 4 CD36 Tbio Non-IDG -2.63884 376.0 1155
V-type proton ATPase subunit D ATP6V1D Tbio Enzyme -1.48812 30.2 69
Importin subunit beta-1 KPNB1 Tbio Non-IDG -1.63038 38.8 174