Development Level

Tbio 168 | 11,445
Tchem 62 | 1,598
Tclin 61 | 613
Tdark 2 | 6,588

Collection

GPCR: IDG Consortium (Complete... 2 | 25

IMPC Phenotype

preweaning lethality, complete... 13 | 979
preweaning lethality, incomple... 13 | 499
abnormal embryo size 6 | 220
embryonic lethality prior to t... 5 | 278
abnormal bone structure 4 | 187
decreased vertical activity 4 | 208
increased lean body mass 4 | 172
increased startle reflex 4 | 112
increased total body fat amoun... 4 | 134
decreased bone mineral content 3 | 151
decreased lean body mass 3 | 135
embryonic growth retardation 3 | 106
embryonic lethality prior to o... 3 | 239
increased circulating sodium l... 3 | 71
increased leukocyte cell numbe... 3 | 47
increased lymphocyte cell numb... 3 | 32
abnormal behavior 2 | 298
abnormal coat-hair pigmentatio... 2 | 64
abnormal eye morphology 2 | 68
abnormal gait 2 | 69
abnormal sleep behavior 2 | 70
abnormal vibrissa morphology 2 | 25
decreased T cell number 2 | 15
decreased circulating calcium ... 2 | 36
decreased circulating sodium l... 2 | 22
decreased grip strength 2 | 116
decreased heart weight 2 | 27
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular hem... 2 | 50
decreased mean corpuscular vol... 2 | 79
decreased red blood cell distr... 2 | 41
decreased total body fat amoun... 2 | 207
edema 2 | 59
impaired glucose tolerance 2 | 75
increased blood urea nitrogen ... 2 | 48
increased bone mineral density 2 | 72
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating triglyce... 2 | 42
increased mean corpuscular hem... 2 | 36
increased mean corpuscular vol... 2 | 92
increased neutrophil cell numb... 2 | 46
increased spleen weight 2 | 10
pale yolk sac 2 | 25
pallor 2 | 34
abnormal craniofacial morpholo... 1 | 33
abnormal femur morphology 1 | 14
abnormal head morphology 1 | 10
abnormal lung morphology 1 | 26
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin coloration 1 | 25
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal vertebrae morphology 1 | 18
absent vibrissae 1 | 12
brachydactyly 1 | 19
cataract 1 | 92
cyanosis 1 | 7
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating bilirubi... 1 | 19
decreased circulating creatini... 1 | 39
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased mature B cell number 1 | 7
decreased neutrophil cell numb... 1 | 42
enlarged spleen 1 | 41
enlarged uterus 1 | 11
hemorrhage 1 | 23
hydrometra 1 | 53
increased body length 1 | 32
increased body weight 1 | 25
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating magnesiu... 1 | 10
increased circulating potassiu... 1 | 29
increased circulating total pr... 1 | 28
increased eosinophil cell numb... 1 | 11
increased large unstained cell... 1 | 5
increased monocyte cell number 1 | 63
limb grasping 1 | 41
mammalian phenotype 1 | 17
premature death 1 | 5
respiratory system phenotype 1 | 2
small spleen 1 | 19
small superior vagus ganglion 1 | 74
small thymus 1 | 16
tremors 1 | 39
unresponsive to tactile stimul... 1 | 8
vertebral transformation 1 | 12

Disease

Cancer 194 | 2,499
Carcinoma 174 | 11,493
psoriasis 167 | 6,694
osteosarcoma 136 | 7,950
ovarian cancer 133 | 8,520
lung cancer 110 | 4,740
medulloblastoma, large-cell 102 | 6,241
diabetes mellitus 101 | 1,728
glioblastoma 101 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 84 | 3,291
lung carcinoma 83 | 2,843
Breast cancer 82 | 3,578
Rheumatoid arthritis 80 | 1,191
atypical teratoid / rhabdoid tumor 80 | 5,112
non-small cell lung cancer 79 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 78 | 2,955
pancreatic cancer 78 | 2,398
ependymoma 76 | 4,679
lung adenocarcinoma 75 | 2,716
malignant mesothelioma 75 | 3,232
invasive ductal carcinoma 74 | 2,951
Astrocytoma, Pilocytic 73 | 3,081
interstitial cystitis 73 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 69 | 2,989
adult high grade glioma 67 | 3,801
dermatomyositis 67 | 966
Hypersensitivity reaction type II disease 66 | 253
Arthritis 59 | 290
ulcerative colitis 59 | 1,819
Autosomal recessive predisposition 55 | 1,442
subependymal giant cell astrocytoma 54 | 2,287
tuberculosis 54 | 2,010
Acquired immunodeficiency syndrome 52 | 197
cystic fibrosis 51 | 1,696
Dermatitis 49 | 157
Kidney cancer 49 | 2,613
Schizophrenia 49 | 1,160
group 3 medulloblastoma 48 | 4,104
oligodendroglioma 48 | 2,850
Human immunodeficiency virus infectious disease 47 | 138
Alzheimer's disease 46 | 658
breast carcinoma 46 | 1,638
Kidney disease 45 | 430
Uveitis 45 | 103
cutaneous lupus erythematosus 44 | 1,057
pituitary cancer 44 | 1,972
ductal carcinoma in situ 43 | 1,745
Synovitis 42 | 78
Ankylosing spondylitis 41 | 140
Juvenile rheumatoid arthritis 41 | 111
primitive neuroectodermal tumor 41 | 3,035
Psoriatic arthritis 40 | 86
Epilepsy 39 | 792
Herpes zoster 39 | 68
Nephritis 39 | 51
Stevens-Johnson syndrome 39 | 92
Behcet's syndrome 38 | 50
Congenital adrenal hyperplasia 38 | 73
Takayasu's arteritis 38 | 53
astrocytic glioma 38 | 2,597
Behcet's disease 37 | 89
primary pancreatic ductal adenocarcinoma 37 | 1,109
Anemia 36 | 365
Heart disease 36 | 306
Retinal vasculitis 36 | 36
Multiple Sclerosis 35 | 540
Spondyloarthropathy, Susceptibility To, 1 35 | 35
drug-induced hepatitis 35 | 44
group 4 medulloblastoma 35 | 1,855
Obesity 34 | 678
active ulcerative colitis 34 | 764
pancreatic ductal adenocarcinoma liver metastasis 34 | 1,962
Prostatic Neoplasms 33 | 495
Breast Neoplasms 32 | 445
Diarrhea 32 | 253
Hypertension 32 | 396
Mammary Neoplasms 32 | 425
Multiple myeloma 32 | 1,332
colon cancer 32 | 1,478
active Crohn's disease 31 | 922
gastric carcinoma 31 | 807
Toxic encephalopathy 30 | 141
nasopharyngeal carcinoma 30 | 1,058
esophageal adenocarcinoma 29 | 737
juvenile dermatomyositis 29 | 1,187
Bipolar Disorder 28 | 666
Liver Cirrhosis, Experimental 28 | 769
Vascular disease 28 | 319
adrenocortical carcinoma 28 | 1,428
Dementia 26 | 175
Liver disease 26 | 237
astrocytoma 26 | 1,146
Down syndrome 25 | 499
Asthma 24 | 385
Cerebrovascular disease 24 | 238
Depressive disorder 24 | 409
Lung Neoplasms 24 | 232
Pick disease 24 | 1,894
Stomach Neoplasms 24 | 300
primary Sjogren syndrome 24 | 735

Tissue

Endocrine System 252 | 18,159
Digestive Tract 248 | 17,369
Female tissues 248 | 17,400
Skin and soft tissues 245 | 17,230
Male tissues 244 | 17,142
Blood and immune system 243 | 16,909
Liver and Pancreas 243 | 16,750
Urinary Tract 243 | 16,678
Nervous System 240 | 16,725
Respiratory system 235 | 16,393
Cardiovascular System 217 | 15,192

Target Family

Non-IDG 172 | 12,091
Enzyme 46 | 4,145
GPCR 20 | 408
Kinase 20 | 634
Ion Channel 18 | 344
Transporter 14 | 473
Transcription Factor 3 | 1,400

Compartment GO Term

Spanning component of plasma m... 293 | 293
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Suppressor of tumorigenicity 14 protein ST14 Tchem Non-IDG -2.50215 338.3 309
Mucin-16 MUC16 Tbio Non-IDG -2.09951 138.4 0
Tumor necrosis factor receptor superfamily member 13C TNFRSF13C Tbio Non-IDG -2.48953 288.2 437
Tetraspanin-16 TSPAN16 Tdark Non-IDG -1.99505 87.0 42
Potassium voltage-gated channel subfamily E member 3 KCNE3 Tbio Ion Channel -1.63683 41.4 75
Atrial natriuretic peptide-converting enzyme CORIN Tbio Non-IDG -2.14443 144.4 221
Melanocyte-stimulating hormone receptor MC1R Tclin GPCR -2.90014 829.2 194
Disintegrin and metalloproteinase domain-containing protein 12 ADAM12 Tchem Enzyme -2.28901 214.1 347
Aquaporin-1 AQP1 Tbio Non-IDG -3.08125 1107.4 374
Adenylate cyclase type 10 ADCY10 Tchem Enzyme -3.13751 1324.4 108