Development Level

Tbio 147 | 10,625
Tchem 71 | 1,890
Tclin 53 | 602
Tdark 4 | 7,003

IMPC Term

preweaning lethality, complete... 11 | 633
preweaning lethality, incomple... 5 | 260
decreased bone mineral content 4 | 157
decreased grip strength 4 | 123
abnormal embryo size 3 | 112
abnormal hindbrain development 3 | 24
abnormal midbrain development 3 | 22
abnormal neural tube closure 3 | 37
embryonic lethality prior to t... 3 | 187
increased mean corpuscular vol... 3 | 91
abnormal behavior 2 | 226
abnormal coat/hair pigmentatio... 2 | 54
abnormal forebrain development 2 | 18
abnormal vibrissa morphology 2 | 17
decreased T cell number 2 | 31
decreased blood urea nitrogen ... 2 | 31
decreased circulating calcium ... 2 | 33
decreased lean body mass 2 | 195
decreased monocyte cell number 2 | 28
embryonic lethality prior to o... 2 | 148
hydrops fetalis 2 | 22
hypoactivity 2 | 89
impaired glucose tolerance 2 | 52
increased bone mineral density 2 | 52
increased circulating alkaline... 2 | 119
increased exploration in new e... 2 | 56
increased mean corpuscular hem... 2 | 25
abnormal QRS complex 1 | 25
abnormal bone structure 1 | 131
abnormal coping response 1 | 12
abnormal digit morphology 1 | 13
abnormal epididymis morphology 1 | 31
abnormal femur morphology 1 | 14
abnormal gait 1 | 51
abnormal head morphology 1 | 10
abnormal lens morphology 1 | 73
abnormal limb bud morphology 1 | 15
abnormal limb morphology 1 | 7
abnormal lung morphology 1 | 15
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
abnormal spinal cord morpholog... 1 | 8
abnormal startle reflex 1 | 14
abnormal tail morphology 1 | 17
absent vibrissae 1 | 14
cyanosis 1 | 6
decreased CD8-positive, alpha-... 1 | 26
decreased basophil cell number 1 | 11
decreased brain size 1 | 4
decreased circulating bilirubi... 1 | 14
decreased circulating creatini... 1 | 31
decreased circulating iron lev... 1 | 25
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased heart weight 1 | 44
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased neutrophil cell numb... 1 | 37
decreased threshold for audito... 1 | 32
edema 1 | 11
enlarged spleen 1 | 26
hemorrhage 1 | 12
herniated abdominal wall 1 | 4
increased B cell number 1 | 23
increased NK T cell number 1 | 11
increased T cell number 1 | 15
increased blood urea nitrogen ... 1 | 44
increased body weight 1 | 42
increased circulating HDL chol... 1 | 63
increased circulating choleste... 1 | 53
increased circulating magnesiu... 1 | 10
increased circulating total pr... 1 | 20
increased eosinophil cell numb... 1 | 9
increased fasted circulating g... 1 | 68
increased gamma-delta T cell n... 1 | 16
increased grip strength 1 | 83
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased mature B cell number 1 | 12
increased respiratory quotient 1 | 12
increased rib number 1 | 41
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
limb grasping 1 | 35
mydriasis 1 | 9
no abnormal phenotype detected 1 | 3
premature death 1 | 5
respiratory system phenotype 1 | 2
small heart 1 | 8
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 11
small stomach 1 | 3
small thymus 1 | 11
tremors 1 | 34
vertebral transformation 1 | 12

Disease

Cancer 181 | 2,346
psoriasis 160 | 6,685
osteosarcoma 131 | 7,933
ovarian cancer 124 | 8,492
lung cancer 101 | 4,473
diabetes mellitus 96 | 1,663
medulloblastoma, large-cell 95 | 6,234
glioblastoma 94 | 5,572
lung carcinoma 81 | 2,844
intraductal papillary-mucinous neoplasm (IPMN) 80 | 3,289
Rheumatoid Arthritis 77 | 1,171
intraductal papillary-mucinous adenoma (IPMA) 77 | 2,956
pancreatic cancer 76 | 2,300
ulcerative colitis 75 | 2,087
lung adenocarcinoma 73 | 2,714
pilocytic astrocytoma 72 | 3,086
invasive ductal carcinoma 71 | 2,950
interstitial cystitis 70 | 2,299
non-small cell lung cancer 70 | 2,798
Breast cancer 69 | 3,099
intraductal papillary-mucinous carcinoma (IPMC) 67 | 2,988
dermatomyositis 65 | 967
atypical teratoid / rhabdoid tumor 64 | 4,369
malignant mesothelioma 63 | 3,163
Hypersensitivity reaction type II disease 62 | 235
Arthritis 55 | 248
pediatric high grade glioma 54 | 2,712
Acquired immunodeficiency syndrome 53 | 164
subependymal giant cell astrocytoma 53 | 2,287
Carcinoma 52 | 2,147
cystic fibrosis 51 | 1,670
tuberculosis 46 | 1,563
Dermatitis 45 | 141
Uveitis 45 | 103
oligodendroglioma 45 | 2,849
Human immunodeficiency virus infectious disease 44 | 129
pituitary cancer 43 | 1,972
primary pancreatic ductal adenocarcinoma 43 | 1,271
Ankylosing spondylitis 42 | 138
Kidney disease 42 | 397
Alzheimer's disease 41 | 644
cutaneous lupus erythematosus 41 | 1,056
ependymoma 41 | 2,514
Psoriatic arthritis 40 | 85
Synovitis 40 | 72
ductal carcinoma in situ 40 | 1,745
Juvenile rheumatoid arthritis 39 | 105
Stevens-Johnson syndrome 39 | 91
breast carcinoma 39 | 1,614
primitive neuroectodermal tumor 39 | 3,031
Behcet's syndrome 38 | 50
Congenital adrenal hyperplasia 38 | 74
Takayasu's arteritis 38 | 54
Behcet's disease 37 | 74
Nephritis 37 | 63
Retinal vasculitis 36 | 36
Heart disease 35 | 279
Spondyloarthropathy, Susceptibility To, 1 35 | 35
drug-induced hepatitis 35 | 44
Prostatic Neoplasms 34 | 471
Multiple Sclerosis 33 | 498
group 4 medulloblastoma 33 | 1,875
gastric carcinoma 31 | 832
astrocytic glioma 30 | 2,241
colon cancer 30 | 1,475
Anemia 29 | 252
Down syndrome 29 | 548
Mammary Neoplasms 29 | 410
Obesity 29 | 616
adult high grade glioma 29 | 2,148
nasopharyngeal carcinoma 29 | 1,056
Hypertension 28 | 293
Multiple myeloma 28 | 1,328
active Crohn's disease 28 | 918
adrenocortical carcinoma 28 | 1,427
astrocytoma 28 | 1,493
pancreatic ductal adenocarcinoma liver metastasis 28 | 1,795
posterior fossa group A ependymoma 28 | 1,511
sonic hedgehog group medulloblastoma 28 | 1,482
Liver disease 27 | 219
Toxic encephalopathy 27 | 131
esophageal adenocarcinoma 26 | 737
juvenile dermatomyositis 26 | 1,189
Schizophrenia 25 | 503
group 3 medulloblastoma 25 | 2,254
primary Sjogren syndrome 25 | 789
Inflammatory bowel disease 24 | 142
Vascular disease 24 | 281
Cerebrovascular disease 23 | 231
Asthma 22 | 349
Atherosclerosis 22 | 275
Diarrhea 22 | 155
Dementia 21 | 129
Duchenne muscular dystrophy 21 | 602
mucosa-associated lymphoid tissue lymphoma 21 | 480
non-small cell lung carcinoma 21 | 413
Adenoma 20 | 165
Endometriosis 20 | 535
Pick disease 20 | 1,893
acute quadriplegic myopathy 20 | 1,157

Tissue

Digestive Tract 241 | 18,473
Endocrine System 241 | 18,512
Female tissues 241 | 18,647
Nervous System 241 | 18,561
Urinary Tract 241 | 18,444
Blood and immune system 239 | 17,995
Liver and Pancreas 239 | 18,136
Cardiovascular System 238 | 17,958
Male tissues 236 | 17,969
Skin and soft tissues 236 | 18,115
Respiratory system 234 | 17,484

Target Family

Non-IDG 165 | 11,969
Enzyme 44 | 4,146
GPCR 19 | 408
Kinase 19 | 634
Ion Channel 15 | 341
Transporter 11 | 473
Transcription Factor 2 | 1,400

Compartment GO Term

Spanning component of plasma m... 275 | 275
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tomoregulin-2 TMEFF2 Tbio Non-IDG -1.85867 81.2 150
Potassium-transporting ATPase alpha chain 2 ATP12A Tchem Transporter -3.80030 5982.8 71
Cadherin-related family member 2 CDHR2 Tbio Non-IDG -0.72369 6.09 28
Disintegrin and metalloproteinase domain-containing protein 9 ADAM9 Tchem Enzyme -2.03866 113.6 184
Caspase-8 CASP8 Tchem Enzyme -3.51864 2954.7 930
Metalloreductase STEAP1 STEAP1 Tbio Enzyme -1.63486 43.9 294
Cadherin-related family member 5 CDHR5 Tbio Non-IDG -0.78477 5.49 125
Calcium-activated potassium channel subunit alpha-1 KCNMA1 Tclin Ion Channel -3.08349 1170.6 213
ATPase ASNA1 ASNA1 Tbio Enzyme -1.80082 72.3 207
CD82 antigen CD82 Tbio Non-IDG -2.60792 421.9 340