Development Level

Tbio 153 | 11,178
Tchem 64 | 1,885
Tclin 61 | 612
Tdark 2 | 6,569

Collection

GPCR: IDG Consortium (Complete... 2 | 25

IMPC Phenotype

preweaning lethality, incomple... 12 | 499
preweaning lethality, complete... 11 | 979
abnormal embryo size 5 | 220
abnormal bone structure 4 | 187
decreased vertical activity 4 | 208
embryonic lethality prior to t... 4 | 278
increased lean body mass 4 | 172
increased startle reflex 4 | 112
increased total body fat amoun... 4 | 134
decreased bone mineral content 3 | 151
decreased lean body mass 3 | 135
embryonic lethality prior to o... 3 | 239
increased circulating sodium l... 3 | 71
increased leukocyte cell numbe... 3 | 47
increased lymphocyte cell numb... 3 | 32
abnormal behavior 2 | 298
abnormal coat-hair pigmentatio... 2 | 64
abnormal gait 2 | 69
abnormal sleep behavior 2 | 70
decreased T cell number 2 | 15
decreased circulating calcium ... 2 | 36
decreased circulating sodium l... 2 | 22
decreased grip strength 2 | 116
decreased heart weight 2 | 27
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular hem... 2 | 50
decreased mean corpuscular vol... 2 | 79
decreased red blood cell distr... 2 | 41
decreased total body fat amoun... 2 | 207
edema 2 | 59
embryonic growth retardation 2 | 106
impaired glucose tolerance 2 | 75
increased bone mineral density 2 | 72
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating triglyce... 2 | 42
increased mean corpuscular hem... 2 | 36
increased mean corpuscular vol... 2 | 92
increased neutrophil cell numb... 2 | 46
increased spleen weight 2 | 10
abnormal craniofacial morpholo... 1 | 33
abnormal femur morphology 1 | 14
abnormal head morphology 1 | 10
abnormal hindbrain morphology 1 | 10
abnormal lung morphology 1 | 26
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin coloration 1 | 25
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
absent vibrissae 1 | 12
cataract 1 | 92
cyanosis 1 | 7
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased brain size 1 | 4
decreased circulating creatini... 1 | 39
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased mature B cell number 1 | 7
decreased neutrophil cell numb... 1 | 42
enlarged spleen 1 | 41
enlarged uterus 1 | 11
hemorrhage 1 | 23
hydrometra 1 | 53
hypoactivity 1 | 132
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased body weight 1 | 25
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating magnesiu... 1 | 10
increased circulating potassiu... 1 | 29
increased circulating total pr... 1 | 28
increased eosinophil cell numb... 1 | 11
increased large unstained cell... 1 | 5
increased monocyte cell number 1 | 63
limb grasping 1 | 41
mammalian phenotype 1 | 17
respiratory system phenotype 1 | 2
small lung 1 | 5
small spleen 1 | 19
small stomach 1 | 3
small superior vagus ganglion 1 | 74
small thymus 1 | 16
tremors 1 | 39
unresponsive to tactile stimul... 1 | 8
vertebral transformation 1 | 12

Disease

Cancer 185 | 2,388
Carcinoma 163 | 11,192
psoriasis 156 | 6,514
osteosarcoma 129 | 7,766
ovarian cancer 125 | 8,297
lung cancer 105 | 4,607
diabetes mellitus 100 | 1,683
glioblastoma 98 | 5,635
medulloblastoma, large-cell 97 | 6,086
Rheumatoid arthritis 78 | 1,156
lung carcinoma 78 | 2,755
intraductal papillary-mucinous neoplasm (IPMN) 77 | 3,204
Breast cancer 76 | 3,469
atypical teratoid / rhabdoid tumor 75 | 4,971
intraductal papillary-mucinous adenoma (IPMA) 74 | 2,872
malignant mesothelioma 73 | 3,135
ependymoma 72 | 4,559
non-small cell lung cancer 71 | 2,799
pancreatic cancer 70 | 2,322
interstitial cystitis 69 | 2,237
lung adenocarcinoma 69 | 2,627
Astrocytoma, Pilocytic 68 | 3,006
invasive ductal carcinoma 68 | 2,867
intraductal papillary-mucinous carcinoma (IPMC) 66 | 2,902
Hypersensitivity reaction type II disease 65 | 245
adult high grade glioma 65 | 3,701
dermatomyositis 65 | 941
Arthritis 58 | 276
ulcerative colitis 57 | 1,765
Autosomal recessive predisposition 54 | 1,407
subependymal giant cell astrocytoma 54 | 2,230
tuberculosis 54 | 1,963
Acquired immunodeficiency syndrome 52 | 192
Dermatitis 49 | 154
Kidney cancer 47 | 2,548
Schizophrenia 47 | 1,136
cystic fibrosis 47 | 1,629
oligodendroglioma 47 | 2,768
Human immunodeficiency virus infectious disease 46 | 136
group 3 medulloblastoma 46 | 4,002
Uveitis 45 | 102
breast carcinoma 44 | 1,589
Kidney disease 43 | 411
cutaneous lupus erythematosus 43 | 1,016
Alzheimer's disease 42 | 640
Synovitis 42 | 75
pituitary cancer 42 | 1,915
Ankylosing spondylitis 41 | 134
Juvenile rheumatoid arthritis 41 | 110
Psoriatic arthritis 40 | 84
primitive neuroectodermal tumor 40 | 2,957
Herpes zoster 39 | 68
Nephritis 39 | 51
Stevens-Johnson syndrome 39 | 92
ductal carcinoma in situ 39 | 1,686
Behcet's syndrome 38 | 49
Congenital adrenal hyperplasia 38 | 71
Epilepsy 38 | 775
Takayasu's arteritis 38 | 53
Behcet's disease 37 | 87
Heart disease 36 | 288
Retinal vasculitis 36 | 36
astrocytic glioma 36 | 2,530
Anemia 35 | 353
Multiple Sclerosis 35 | 527
Spondyloarthropathy, Susceptibility To, 1 35 | 35
drug-induced hepatitis 35 | 44
primary pancreatic ductal adenocarcinoma 34 | 1,071
Obesity 33 | 655
Diarrhea 32 | 245
active ulcerative colitis 32 | 736
group 4 medulloblastoma 32 | 1,806
Hypertension 31 | 372
Multiple myeloma 31 | 1,296
colon cancer 31 | 1,428
pancreatic ductal adenocarcinoma liver metastasis 31 | 1,911
Breast Neoplasms 30 | 423
Mammary Neoplasms 30 | 403
Prostatic Neoplasms 29 | 472
Toxic encephalopathy 29 | 139
gastric carcinoma 29 | 781
juvenile dermatomyositis 28 | 1,147
Bipolar Disorder 27 | 646
active Crohn's disease 27 | 882
adrenocortical carcinoma 27 | 1,385
esophageal adenocarcinoma 27 | 696
Liver Cirrhosis, Experimental 26 | 733
Liver disease 26 | 227
Vascular disease 26 | 294
nasopharyngeal carcinoma 26 | 1,024
Dementia 25 | 172
astrocytoma 25 | 1,113
Asthma 24 | 370
Stomach Neoplasms 24 | 287
Cerebrovascular disease 23 | 223
Depressive disorder 23 | 401
Down syndrome 23 | 480
Inflammatory bowel disease 23 | 148
Melanoma 23 | 689
primary Sjogren syndrome 23 | 710

Tissue

Endocrine System 239 | 18,159
Digestive Tract 235 | 17,369
Female tissues 235 | 17,400
Skin and soft tissues 232 | 17,230
Male tissues 231 | 17,142
Blood and immune system 230 | 16,909
Liver and Pancreas 230 | 16,750
Urinary Tract 230 | 16,678
Nervous System 227 | 16,725
Respiratory system 222 | 16,393
Cardiovascular System 206 | 15,192

Target Family

Non-IDG 168 | 12,091
Enzyme 37 | 4,145
GPCR 20 | 408
Kinase 20 | 634
Ion Channel 18 | 344
Transporter 14 | 473
Transcription Factor 3 | 1,400

Compartment GO Term

Spanning component of plasma m... 280 | 280
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, B-67 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 362
Tumor necrosis factor receptor superfamily member 1B TNFRSF1B Tchem Non-IDG -3.67481 4484.7 712
Transient receptor potential cation channel subfamily M member 4 TRPM4 Tchem Ion Channel -2.19653 160.9 186
Transmembrane channel-like protein 2 TMC2 Tbio Ion Channel -1.19934 15.1 35
Transmembrane channel-like protein 1 TMC1 Tbio Ion Channel -1.99724 101.1 20
Beta-2 adrenergic receptor ADRB2 Tclin GPCR -3.22695 1680.9 829
Receptor tyrosine-protein kinase erbB-4 ERBB4 Tclin Kinase -2.78704 558.2 1072
Gap junction beta-2 protein GJB2 Tbio Non-IDG -3.17642 1514.7 242
HLA class I histocompatibility antigen, B-59 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
5-hydroxytryptamine receptor 7 HTR7 Tclin GPCR -4.15964 13643.7 259