Development Level

Tbio 272 | 11,445
Tchem 70 | 1,598
Tclin 52 | 613
Tdark 23 | 6,588

Collection

Ion Channel: IDG Consortium (T... 7 | 99
Kinase: IDG Consortium (Comple... 2 | 37
GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 22 | 979
abnormal behavior 19 | 298
preweaning lethality, incomple... 15 | 499
decreased total body fat amoun... 10 | 207
decreased vertical activity 10 | 208
hyperactivity 10 | 148
abnormal bone structure 8 | 187
decreased grip strength 8 | 116
embryonic lethality prior to t... 8 | 278
embryonic lethality prior to o... 7 | 239
increased bone mineral content 7 | 108
increased circulating chloride... 7 | 41
increased circulating sodium l... 7 | 71
increased lean body mass 7 | 172
increased total body fat amoun... 7 | 134
abnormal locomotor behavior 6 | 24
decreased bone mineral content 6 | 151
decreased circulating alkaline... 6 | 46
decreased lean body mass 6 | 135
edema 6 | 59
impaired glucose tolerance 6 | 75
abnormal retina morphology 5 | 71
decreased body weight 5 | 161
prolonged QT interval 5 | 38
prolonged ST segment 5 | 36
tremors 5 | 39
abnormal behavioral response t... 4 | 66
abnormal embryo size 4 | 220
decreased circulating HDL chol... 4 | 68
decreased circulating choleste... 4 | 93
decreased circulating serum al... 4 | 82
decreased mean corpuscular vol... 4 | 79
decreased startle reflex 4 | 75
hypoactivity 4 | 132
increased circulating alkaline... 4 | 122
increased circulating triglyce... 4 | 42
increased heart weight 4 | 62
increased or absent threshold ... 4 | 101
abnormal eye morphology 3 | 68
abnormal gait 3 | 69
abnormal sleep behavior 3 | 70
cataract 3 | 92
decreased circulating alanine ... 3 | 47
decreased circulating aspartat... 3 | 34
decreased circulating glucose ... 3 | 126
decreased fasted circulating g... 3 | 65
enlarged heart 3 | 210
improved glucose tolerance 3 | 79
increased fasted circulating g... 3 | 76
increased mean corpuscular vol... 3 | 92
increased red blood cell distr... 3 | 34
increased startle reflex 3 | 112
limb grasping 3 | 41
short tibia 3 | 97
thin ventricular wall 3 | 24
abnormal epididymis morphology 2 | 42
abnormal lens morphology 2 | 81
abnormal pericardium morpholog... 2 | 26
abnormal retinal vasculature m... 2 | 27
abnormal vertebrae morphology 2 | 18
decreased basophil cell number 2 | 16
decreased bone mineral density 2 | 126
decreased circulating LDL chol... 2 | 38
decreased circulating insulin ... 2 | 76
decreased circulating total pr... 2 | 49
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased heart left ventricle... 2 | 28
decreased lymphocyte cell numb... 2 | 83
decreased pulmonary respirator... 2 | 5
embryonic growth retardation 2 | 106
enlarged stomach 2 | 2
hemorrhage 2 | 23
increased blood urea nitrogen ... 2 | 48
increased circulating amylase ... 2 | 25
increased circulating choleste... 2 | 66
increased circulating phosphat... 2 | 26
increased neutrophil cell numb... 2 | 46
increased prepulse inhibition 2 | 32
increased spleen weight 2 | 10
increased vertical activity 2 | 24
pallor 2 | 34
prenatal lethality prior to he... 2 | 87
small superior vagus ganglion 2 | 74
small thymus 2 | 16
thrombocytosis 2 | 27
abnormal cranium morphology 1 | 36
abnormal retinal inner nuclear... 1 | 8
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased body length 1 | 101
decreased circulating amylase ... 1 | 28
decreased eosinophil cell numb... 1 | 24
decreased neutrophil cell numb... 1 | 42
decreased total retina thickne... 1 | 17
impaired pupillary reflex 1 | 26
increased aggression 1 | 4
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating iron lev... 1 | 30

Disease

Carcinoma 305 | 11,493
medulloblastoma, large-cell 243 | 6,241
glioblastoma 233 | 5,792
atypical teratoid / rhabdoid tumor 223 | 5,112
ependymoma 206 | 4,679
ovarian cancer 191 | 8,520
osteosarcoma 184 | 7,950
adult high grade glioma 182 | 3,801
psoriasis 173 | 6,694
Astrocytoma, Pilocytic 168 | 3,081
oligodendroglioma 162 | 2,850
group 3 medulloblastoma 160 | 4,104
primitive neuroectodermal tumor 141 | 3,035
lung cancer 139 | 4,740
Schizophrenia 136 | 1,160
astrocytic glioma 134 | 2,597
Kidney cancer 126 | 2,613
Breast cancer 109 | 3,578
Cancer 102 | 2,499
Alzheimer's disease 96 | 658
Pick disease 96 | 1,894
lung carcinoma 92 | 2,843
subependymal giant cell astrocytoma 91 | 2,287
Bipolar Disorder 89 | 666
malignant mesothelioma 88 | 3,232
intraductal papillary-mucinous carcinoma (IPMC) 87 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 87 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 85 | 2,955
Epilepsy 84 | 792
invasive ductal carcinoma 83 | 2,951
pituitary cancer 82 | 1,972
Depressive disorder 74 | 409
non-small cell lung cancer 68 | 2,890
Intellectual disability 67 | 1,016
Parkinson's disease 67 | 392
Mental Depression 64 | 333
group 4 medulloblastoma 64 | 1,855
Seizures 61 | 596
interstitial cystitis 60 | 2,312
lung adenocarcinoma 60 | 2,716
Alcoholic Intoxication, Chronic 58 | 289
colon cancer 58 | 1,478
Neurodegenerative disease 57 | 414
diabetes mellitus 57 | 1,728
pancreatic cancer 56 | 2,398
Toxic encephalopathy 54 | 141
cystic fibrosis 49 | 1,696
Autistic Disorder 48 | 364
Melanoma 47 | 711
ulcerative colitis 47 | 1,819
Major Depressive Disorder 46 | 301
astrocytoma 45 | 1,146
breast carcinoma 45 | 1,638
ductal carcinoma in situ 45 | 1,745
tuberculosis 45 | 2,010
Dementia 43 | 175
Liver cancer 43 | 604
Autosomal recessive predisposition 42 | 1,442
Mood Disorders 41 | 184
Down syndrome 40 | 499
Obesity 40 | 678
Skin cancer 40 | 469
Amyotrophic lateral sclerosis 39 | 451
Cerebrovascular disease 38 | 238
Unipolar Depression 36 | 250
adrenocortical carcinoma 36 | 1,428
pancreatic ductal adenocarcinoma liver metastasis 36 | 1,962
pediatric high grade glioma 36 | 1,064
acute quadriplegic myopathy 35 | 1,158
Multiple Sclerosis 34 | 540
juvenile dermatomyositis 31 | 1,187
Dull intelligence 30 | 645
Hypertension 30 | 396
Low intelligence 30 | 645
Mental Retardation 30 | 645
Mental deficiency 30 | 645
Poor school performance 30 | 645
progressive supranuclear palsy 30 | 676
Cocaine-Related Disorders 29 | 92
cutaneous lupus erythematosus 29 | 1,057
spina bifida 29 | 1,074
Attention deficit hyperactivity disorder 28 | 278
Multiple myeloma 28 | 1,332
Rheumatoid arthritis 28 | 1,191
Neuropathy 27 | 261
aldosterone-producing adenoma 27 | 665
Atopic dermatitis 26 | 952
Huntington's disease 26 | 76
Pain agnosia 26 | 104
Heart disease 25 | 306
non primary Sjogren syndrome sicca 24 | 891
Alcohol dependence 23 | 107
Brain disease 23 | 96
Cerebellar Ataxia 23 | 304
Asthma 22 | 385
Cognitive delay 22 | 608
Duchenne muscular dystrophy 22 | 601
Global developmental delay 22 | 608
Mental and motor retardation 22 | 608
dermatomyositis 22 | 966

Tissue

Endocrine System 408 | 18,159
Nervous System 399 | 16,725
Female tissues 398 | 17,400
Digestive Tract 392 | 17,369
Skin and soft tissues 391 | 17,230
Male tissues 390 | 17,142
Liver and Pancreas 385 | 16,750
Blood and immune system 378 | 16,909
Urinary Tract 378 | 16,678
Respiratory system 363 | 16,393
Cardiovascular System 339 | 15,192

Target Family

Non-IDG 244 | 12,091
Enzyme 64 | 4,145
Ion Channel 39 | 344
Kinase 27 | 634
GPCR 19 | 408
Transporter 13 | 473
Transcription Factor 6 | 1,400
Epigenetic 4 | 242
Nuclear Receptor 1 | 48

Compartment GO Term

Somatodendritic compartment 417 | 417
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sorting nexin-14 SNX14 Tbio Non-IDG -0.86091 6.82 56
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
Huntingtin HTT Tchem Non-IDG -3.36282 2294.8 599
Neuronal vesicle trafficking-associated protein 1 NSG1 Tbio Non-IDG -1.15265 16.1 182
Serine/threonine-protein kinase TAO2 TAOK2 Tchem Kinase -1.52454 36.1 154
Gap junction delta-2 protein GJD2 Tbio Non-IDG -2.48933 326.9 192
Potassium voltage-gated channel subfamily E member 3 KCNE3 Tbio Ion Channel -1.63683 41.4 75
Signal-induced proliferation-associated 1-like protein 1 SIPA1L1 Tbio Non-IDG -0.56258 5.05 40
Calbindin CALB1 Tbio Non-IDG -3.31956 2149.9 287
Dual specificity tyrosine-phosphorylation-regulated kinase 1A DYRK1A Tchem Kinase -2.68760 506.6 336