Development Level

Tbio 64 | 11,651
Tdark 24 | 6,593
Tchem 4 | 1,388

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 6 | 979
embryonic lethality prior to o... 3 | 239
prenatal lethality prior to he... 2 | 87
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal lens morphology 1 | 81
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
cataract 1 | 92
decreased vertical activity 1 | 208
enlarged heart 1 | 210
hemorrhage 1 | 23
increased circulating creatini... 1 | 38
increased lean body mass 1 | 172
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38

Disease

ovarian cancer 47 | 8,520
lung cancer 42 | 4,740
osteosarcoma 29 | 7,950
Carcinoma 26 | 11,493
medulloblastoma, large-cell 21 | 6,241
psoriasis 20 | 6,694
Multiple myeloma 19 | 1,332
glioblastoma 19 | 5,792
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,962
atypical teratoid / rhabdoid tumor 16 | 5,112
diabetes mellitus 16 | 1,728
Cancer 14 | 2,499
Diamond-Blackfan anemia 14 | 31
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
malignant mesothelioma 12 | 3,232
Anemia 11 | 365
group 3 medulloblastoma 11 | 4,104
Breast Neoplasms 10 | 445
Mammary Neoplasms 10 | 425
non-small cell lung cancer 10 | 2,890
Breast cancer 9 | 3,578
Fatigue 9 | 182
Pallor 9 | 40
Abnormality of the urinary system 8 | 21
Anemia, Diamond-Blackfan 8 | 16
Anemia, Macrocytic 8 | 18
Cardiac Arrhythmia 8 | 103
Cardiac conduction abnormalities 8 | 78
Cleft Palate 8 | 271
Conduction disorder of the heart 8 | 79
Delayed Puberty 8 | 97
EKG abnormalities 8 | 78
Electrocardiogram abnormal 8 | 81
Electrocardiogram change 8 | 78
Hand deformities 8 | 32
Intermittent migraine headaches 8 | 68
Migraine Disorders 8 | 76
Uranostaphyloschisis 8 | 167
acute myeloid leukemia 8 | 783
genital abnormal 8 | 17
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
oligodendroglioma 8 | 2,850
reproductive system abnormality 8 | 17
subependymal giant cell astrocytoma 8 | 2,287
Disease Progression 7 | 136
Stomach Neoplasms 7 | 300
Waldenstrons macroglobulinemia 7 | 765
astrocytoma 7 | 1,146
ependymoma 7 | 4,679
adult high grade glioma 6 | 3,801
colon cancer 6 | 1,478
cystic fibrosis 6 | 1,696
lung adenocarcinoma 6 | 2,716
primitive neuroectodermal tumor 6 | 3,035
acute quadriplegic myopathy 5 | 1,158
lung carcinoma 5 | 2,843
non primary Sjogren syndrome sicca 5 | 891
pediatric high grade glioma 5 | 1,064
Astrocytoma, Pilocytic 4 | 3,081
Infantile onset 4 | 238
Kidney cancer 4 | 2,613
Reticulocytopenia 4 | 10
invasive ductal carcinoma 4 | 2,951
medulloblastoma 4 | 720
pancreatic cancer 4 | 2,398
sonic hedgehog group medulloblastoma 4 | 467
Adenocarcinoma of lung 3 | 142
Autosomal recessive predisposition 3 | 1,442
Bowen-Conradi syndrome 3 | 16
Disease Models, Animal 3 | 155
Downward slant of palpebral fissure 3 | 158
Hereditary spherocytosis type 4 3 | 18
Hypertension 3 | 396
Hypoplastic mandible condyle 3 | 275
Irregular astigmatism 3 | 12
Mandibular hypoplasia 3 | 275
Micrognathism 3 | 275
Retinitis pigmentosa 29 3 | 6
Short stature 3 | 531
astrocytic glioma 3 | 2,597
hereditary spastic paraplegia 3 | 318
juvenile dermatomyositis 3 | 1,187
mucosa-associated lymphoid tissue lymphoma 3 | 484
primary pancreatic ductal adenocarcinoma 3 | 1,109
spina bifida 3 | 1,074
Byzanthine arch palate 2 | 194
Congenital Epicanthus 2 | 177
Failure to gain weight 2 | 365
Hemoglobin low 2 | 124
Kidney disease 2 | 430
Pediatric failure to thrive 2 | 365
Peripheral vascular disease 2 | 87
Pick disease 2 | 1,894
Polycystic ovary syndrome 2 | 360
aldosterone-producing adenoma 2 | 665
dermatomyositis 2 | 966
glioblastoma multiforme 2 | 142
tuberculosis 2 | 2,010
tuberculosis and treatment for 3 months 2 | 179

Tissue

Blood and immune system 90 | 16,909
Endocrine System 90 | 18,159
Male tissues 90 | 17,142
Cardiovascular System 89 | 15,192
Digestive Tract 89 | 17,369
Female tissues 89 | 17,400
Liver and Pancreas 89 | 16,750
Nervous System 89 | 16,725
Respiratory system 89 | 16,393
Skin and soft tissues 89 | 17,230
Urinary Tract 89 | 16,678

Target Family

Non-IDG 88 | 12,091
Enzyme 2 | 4,145
Epigenetic 1 | 242
Kinase 1 | 634

Compartment GO Term

Small ribosomal subunit 92 | 92
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Eukaryotic translation initiation factor 1 EIF1 Tbio Non-IDG -2.06392 118.5 92
28S ribosomal protein S14, mitochondrial MRPS14 Tdark Non-IDG 0.30 0.11 22
Eukaryotic translation initiation factor 2 subunit 1 EIF2S1 Tbio Non-IDG -2.81111 643.5 577
39S ribosomal protein L42, mitochondrial MRPL42 Tdark Non-IDG 0.02 0.40 139
28S ribosomal protein S18b, mitochondrial MRPS18B Tdark Non-IDG -0.67793 4.10 45
39S ribosomal protein S18a, mitochondrial MRPS18A Tdark Non-IDG 0.32 0.72 57
RNA-binding protein NOB1 NOB1 Tbio Non-IDG -1.79570 57.2 143
40S ribosomal protein S7 RPS7 Tbio Non-IDG -1.84836 69.5 112
28S ribosomal protein S29, mitochondrial DAP3 Tbio Non-IDG -1.22289 22.6 312
Bystin BYSL Tbio Non-IDG -1.23828 16.6 66