Development Level

Tbio 37 | 11,445
Tdark 5 | 6,588

IMPC Phenotype

preweaning lethality, complete... 4 | 979
decreased body weight 2 | 161
abnormal coat-hair pigmentatio... 1 | 64
abnormal lens morphology 1 | 81
abnormal vibrissa morphology 1 | 25
cataract 1 | 92
decreased NK cell number 1 | 2
decreased circulating chloride... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating sodium l... 1 | 22
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased mean platelet volume 1 | 45
increased startle reflex 1 | 112

Disease

ovarian cancer 27 | 8,520
lung cancer 24 | 4,740
Carcinoma 23 | 11,493
osteosarcoma 14 | 7,950
medulloblastoma, large-cell 13 | 6,241
colon cancer 12 | 1,478
malignant mesothelioma 11 | 3,232
group 3 medulloblastoma 10 | 4,104
Multiple myeloma 9 | 1,332
glioblastoma 9 | 5,792
psoriasis 9 | 6,694
atypical teratoid / rhabdoid tumor 8 | 5,112
Dyskeratosis congenita 7 | 24
Waldenstrons macroglobulinemia 7 | 765
non-small cell lung cancer 7 | 2,890
acute quadriplegic myopathy 6 | 1,158
non primary Sjogren syndrome sicca 6 | 891
Adenocarcinoma of lung 5 | 142
Disease Models, Animal 5 | 155
acute myeloid leukemia 5 | 783
astrocytic glioma 5 | 2,597
ependymoma 5 | 4,679
invasive ductal carcinoma 5 | 2,951
primitive neuroectodermal tumor 5 | 3,035
subependymal giant cell astrocytoma 5 | 2,287
Breast cancer 4 | 3,578
Cancer 4 | 2,499
Intellectual disability 4 | 1,016
Osteoporosis 4 | 363
Skin Ulcer 4 | 48
adult high grade glioma 4 | 3,801
diabetes mellitus 4 | 1,728
pancreatic cancer 4 | 2,398
pancreatic carcinoma 4 | 562
Abnormal blistering of the skin 3 | 54
Abnormality of female internal genitalia 3 | 13
Abnormality of the fingernails 3 | 51
Abnormality of the pharynx 3 | 19
Anemia 3 | 365
Anorectal Malformations 3 | 8
Aplasia/Hypoplasia of the skin 3 | 16
Autosomal recessive predisposition 3 | 1,442
Blister of skin 3 | 54
Blood Coagulation Disorders 3 | 42
Bone marrow hypocellularity 3 | 20
Cellular immunodeficiency 3 | 17
Coagulation abnormalities 3 | 27
Cognitive delay 3 | 608
Decreased platelet count 3 | 111
Dental caries 3 | 164
Dull intelligence 3 | 645
Dystrophia unguium 3 | 53
Esophageal Stenosis 3 | 15
Fetal Growth Retardation 3 | 189
Frequent fractures 3 | 53
Gingival Diseases 3 | 19
Global developmental delay 3 | 608
Hemoglobin low 3 | 124
Hemorrhagic Disorders 3 | 30
Hyperhidrosis disorder 3 | 81
Hyperpigmentation 3 | 37
Hyperpigmented macules 3 | 42
Hypodontia 3 | 81
Hypoplastic-absent toenails 3 | 11
Increased fracture rate 3 | 53
Increased sweating 3 | 81
Infant, Small for Gestational Age 3 | 176
Intrauterine retardation 3 | 176
Large elongated pulp chamber 3 | 14
Leukokeratosis 3 | 19
Leukoplakia, Oral 3 | 20
Liver Cirrhosis 3 | 181
Low intelligence 3 | 645
Malabsorption 3 | 82
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Neutrophil abnormality 3 | 20
Periodontal Diseases 3 | 21
Poor school performance 3 | 645
Recurrent respiratory infections 3 | 141
Rough bone trabeculation 3 | 11
Short stature 3 | 531
Skin bulla 3 | 54
Small head 3 | 374
Sparse hair 3 | 59
Sweating 3 | 81
Systemic scleroderma 3 | 60
Taurodontism 3 | 14
Telangiectasia of the skin 3 | 39
Thin, sparse hair 3 | 59
Thrombocytopenia 3 | 197
Tracheoesophageal Fistula 3 | 36
Urethral Stricture 3 | 18
Varying degree of multiple fractures 3 | 53
cutaneous lupus erythematosus 3 | 1,057
hypopigmented skin patch 3 | 59
oligodendroglioma 3 | 2,850
periodontitis 3 | 293
pituitary cancer 3 | 1,972

Tissue

Blood and immune system 42 | 16,909
Cardiovascular System 42 | 15,192
Digestive Tract 42 | 17,369
Endocrine System 42 | 18,159
Female tissues 42 | 17,400
Liver and Pancreas 42 | 16,750
Male tissues 42 | 17,142
Nervous System 42 | 16,725
Respiratory system 42 | 16,393
Skin and soft tissues 42 | 17,230
Urinary Tract 42 | 16,678

Target Family

Non-IDG 27 | 12,091
Enzyme 15 | 4,145

Compartment GO Term

Small nucleolar ribonucleoprot... 42 | 42
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pseudouridylate synthase 7 homolog PUS7 Tbio Enzyme -1.01773 8.78 58
Probable ATP-dependent RNA helicase DDX52 DDX52 Tbio Enzyme -1.26645 18.0 73
Nucleolar protein 58 NOP58 Tbio Non-IDG -1.46442 30.0 85
39S ribosomal protein L1, mitochondrial MRPL1 Tdark Non-IDG -0.74448 4.18 128
H/ACA ribonucleoprotein complex subunit 2 NHP2 Tbio Non-IDG -1.51951 28.7 54
Box C/D snoRNA protein 1 ZNHIT6 Tbio Non-IDG 0.48 0.74 87
H/ACA ribonucleoprotein complex subunit 3 NOP10 Tbio Non-IDG -1.36742 17.7 34
Periodic tryptophan protein 2 homolog PWP2 Tdark Non-IDG -1.32608 0.00000 109
H/ACA ribonucleoprotein complex non-core subunit NAF1 NAF1 Tbio Non-IDG 0.00000 27
Ribonuclease P protein subunit p40 RPP40 Tdark Enzyme -0.49995 2.84 45