Development Level

Tbio 37 | 11,178
Tdark 5 | 6,569

IMPC Phenotype

preweaning lethality, complete... 4 | 979
decreased body weight 2 | 161
abnormal coat-hair pigmentatio... 1 | 64
abnormal lens morphology 1 | 81
abnormal vibrissa morphology 1 | 25
cataract 1 | 92
decreased NK cell number 1 | 2
decreased circulating chloride... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating sodium l... 1 | 22
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased mean platelet volume 1 | 45
increased startle reflex 1 | 112

Disease

ovarian cancer 27 | 8,297
lung cancer 24 | 4,607
Carcinoma 23 | 11,192
osteosarcoma 14 | 7,766
medulloblastoma, large-cell 13 | 6,086
colon cancer 12 | 1,428
malignant mesothelioma 11 | 3,135
group 3 medulloblastoma 10 | 4,002
Multiple myeloma 9 | 1,296
glioblastoma 9 | 5,635
psoriasis 9 | 6,514
atypical teratoid / rhabdoid tumor 8 | 4,971
Dyskeratosis congenita 7 | 24
Waldenstrons macroglobulinemia 7 | 742
non-small cell lung cancer 7 | 2,799
acute quadriplegic myopathy 6 | 1,133
non primary Sjogren syndrome sicca 6 | 861
Adenocarcinoma of lung 5 | 140
Disease Models, Animal 5 | 148
acute myeloid leukemia 5 | 760
astrocytic glioma 5 | 2,530
ependymoma 5 | 4,559
invasive ductal carcinoma 5 | 2,867
primitive neuroectodermal tumor 5 | 2,957
subependymal giant cell astrocytoma 5 | 2,230
Breast cancer 4 | 3,469
Cancer 4 | 2,388
Intellectual disability 4 | 998
Osteoporosis 4 | 348
Skin Ulcer 4 | 48
adult high grade glioma 4 | 3,701
diabetes mellitus 4 | 1,683
pancreatic cancer 4 | 2,322
pancreatic carcinoma 4 | 555
Abnormal blistering of the skin 3 | 52
Abnormality of female internal genitalia 3 | 13
Abnormality of the fingernails 3 | 51
Abnormality of the pharynx 3 | 19
Anemia 3 | 353
Anorectal Malformations 3 | 8
Aplasia/Hypoplasia of the skin 3 | 16
Autosomal recessive predisposition 3 | 1,407
Blister of skin 3 | 52
Blood Coagulation Disorders 3 | 41
Bone marrow hypocellularity 3 | 20
Cellular immunodeficiency 3 | 17
Coagulation abnormalities 3 | 27
Cognitive delay 3 | 596
Decreased platelet count 3 | 110
Dental caries 3 | 157
Dull intelligence 3 | 634
Dystrophia unguium 3 | 52
Esophageal Stenosis 3 | 14
Fetal Growth Retardation 3 | 186
Frequent fractures 3 | 52
Gingival Diseases 3 | 19
Global developmental delay 3 | 596
Hemoglobin low 3 | 123
Hemorrhagic Disorders 3 | 29
Hyperhidrosis disorder 3 | 78
Hyperpigmentation 3 | 35
Hyperpigmented macules 3 | 41
Hypodontia 3 | 81
Hypoplastic-absent toenails 3 | 11
Increased fracture rate 3 | 52
Increased sweating 3 | 78
Infant, Small for Gestational Age 3 | 174
Intrauterine retardation 3 | 174
Large elongated pulp chamber 3 | 14
Leukokeratosis 3 | 19
Leukoplakia, Oral 3 | 20
Liver Cirrhosis 3 | 173
Low intelligence 3 | 634
Malabsorption 3 | 81
Mental Retardation 3 | 634
Mental and motor retardation 3 | 596
Mental deficiency 3 | 634
Neutrophil abnormality 3 | 20
Periodontal Diseases 3 | 21
Poor school performance 3 | 634
Recurrent respiratory infections 3 | 138
Rough bone trabeculation 3 | 11
Short stature 3 | 514
Skin bulla 3 | 52
Small head 3 | 366
Sparse hair 3 | 59
Sweating 3 | 78
Systemic scleroderma 3 | 57
Taurodontism 3 | 14
Telangiectasia of the skin 3 | 38
Thin, sparse hair 3 | 59
Thrombocytopenia 3 | 193
Tracheoesophageal Fistula 3 | 33
Urethral Stricture 3 | 17
Varying degree of multiple fractures 3 | 52
cutaneous lupus erythematosus 3 | 1,016
hypopigmented skin patch 3 | 59
oligodendroglioma 3 | 2,768
periodontitis 3 | 280
pituitary cancer 3 | 1,915

Tissue

Blood and immune system 42 | 16,909
Cardiovascular System 42 | 15,192
Digestive Tract 42 | 17,369
Endocrine System 42 | 18,159
Female tissues 42 | 17,400
Liver and Pancreas 42 | 16,750
Male tissues 42 | 17,142
Nervous System 42 | 16,725
Respiratory system 42 | 16,393
Skin and soft tissues 42 | 17,230
Urinary Tract 42 | 16,678

Target Family

Non-IDG 27 | 12,091
Enzyme 15 | 4,145

Compartment GO Term

Small nucleolar ribonucleoprot... 42 | 42
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Periodic tryptophan protein 2 homolog PWP2 Tdark Non-IDG -1.32608 0.00000 109
H/ACA ribonucleoprotein complex non-core subunit NAF1 NAF1 Tbio Non-IDG 0.00000 27
Ribosome biogenesis protein BMS1 homolog BMS1 Tbio Non-IDG -1.44213 28.2 53
Protein RRP5 homolog PDCD11 Tdark Non-IDG -1.49282 31.3 34
Ribonuclease P protein subunit p38 RPP38 Tbio Enzyme -1.03790 11.1 83
NHP2-like protein 1 SNU13 Tbio Non-IDG -1.76304 55.2 78
H/ACA ribonucleoprotein complex subunit 3 NOP10 Tbio Non-IDG -1.36742 17.7 34
Ribonucleases P/MRP protein subunit POP1 POP1 Tbio Enzyme 0.00000 56
Serine/arginine-rich splicing factor 5 SRSF5 Tbio Non-IDG -1.56015 31.7 80
Probable ATP-dependent RNA helicase DDX52 DDX52 Tbio Enzyme -1.26645 18.0 73