Development Level

Tbio 265 | 10,625
Tchem 76 | 1,890
Tclin 34 | 602
Tdark 19 | 7,003

Collection

Ion Channel: IDG Consortium (Targets) 3 | 102
GPCR: IDG Consortium (Targets) 1 | 128
Kinase: IDG Consortium (Complete/Control) 1 | 37

IMPC Phenotype

preweaning lethality, complete... 16 | 633
preweaning lethality, incomple... 7 | 260
abnormal behavior 6 | 226
abnormal bone structure 6 | 131
decreased total body fat amoun... 6 | 186
abnormal bone mineralization 5 | 55
decreased bone mineral content 5 | 157
decreased body weight 4 | 174
enlarged heart 4 | 111
increased heart weight 4 | 37
decreased NK T cell number 3 | 28
decreased bone mineral density 3 | 126
decreased circulating HDL chol... 3 | 77
decreased circulating alanine ... 3 | 53
decreased circulating choleste... 3 | 85
decreased circulating triglyce... 3 | 83
decreased fasted circulating g... 3 | 49
decreased grip strength 3 | 123
hypoactivity 3 | 89
increased CD4-positive, alpha ... 3 | 15
increased bone mineral content 3 | 92
increased circulating phosphat... 3 | 24
increased fasted circulating g... 3 | 68
increased lean body mass 3 | 107
abnormal QRS complex 2 | 25
abnormal heart morphology 2 | 51
abnormal kidney morphology 2 | 30
abnormal retina morphology 2 | 100
abnormal retinal pigmentation 2 | 61
abnormal seminal vesicle morph... 2 | 47
abnormal sleep behavior 2 | 63
abnormal spleen morphology 2 | 36
corneal opacity 2 | 25
decreased T cell number 2 | 31
decreased circulating LDL chol... 2 | 37
decreased circulating calcium ... 2 | 33
decreased circulating insulin ... 2 | 75
decreased circulating phosphat... 2 | 15
decreased lean body mass 2 | 195
decreased prepulse inhibition 2 | 52
enlarged spleen 2 | 26
impaired righting response 2 | 19
increased body weight 2 | 42
increased circulating potassiu... 2 | 31
increased grip strength 2 | 83
increased hematocrit 2 | 36
increased leukocyte cell numbe... 2 | 37
increased mean corpuscular vol... 2 | 91
increased or absent threshold ... 2 | 128
male infertility 2 | 62
thrombocytopenia 2 | 46
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal gait 1 | 51
abnormal hair growth 1 | 8
abnormal liver morphology 1 | 5
abnormal lung morphology 1 | 15
abnormal rib morphology 1 | 28
abnormal testis morphology 1 | 30
abnormal vertebrae morphology 1 | 14
abnormal vocalization 1 | 21
absent pinna reflex 1 | 21
cardiovascular system phenotyp... 1 | 35
decreased body length 1 | 108
decreased circulating potassiu... 1 | 17
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased exploration in new e... 1 | 9
decreased heart weight 1 | 44
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased mean corpuscular vol... 1 | 50
decreased neutrophil cell numb... 1 | 37
embryonic lethality prior to t... 1 | 187
enlarged heart atrium 1 | 2
female infertility 1 | 34
hydrometra 1 | 13
increased NK cell number 1 | 19
increased blood urea nitrogen ... 1 | 44
increased body length 1 | 20
increased circulating HDL chol... 1 | 63
increased circulating alkaline... 1 | 119
increased circulating calcium ... 1 | 32
increased circulating chloride... 1 | 43
increased circulating creatini... 1 | 29
increased circulating sodium l... 1 | 71
increased effector memory CD4-... 1 | 15
increased erythrocyte cell num... 1 | 26
increased hemoglobin content 1 | 45
increased respiratory quotient 1 | 12
increased startle reflex 1 | 38
polycystic kidney 1 | 9
prenatal lethality 1 | 16
prenatal lethality prior to he... 1 | 64
rough coat 1 | 1
small testis 1 | 37
sparse hair 1 | 6
straub tail 1 | 26
tremors 1 | 34
vertebral fusion 1 | 23

Disease

Cancer 198 | 2,346
psoriasis 178 | 6,685
osteosarcoma 177 | 7,933
ovarian cancer 168 | 8,491
medulloblastoma, large-cell 134 | 6,234
glioblastoma 127 | 5,572
diabetes mellitus 119 | 1,663
lung cancer 110 | 4,473
lung carcinoma 101 | 2,844
pilocytic astrocytoma 92 | 3,086
Rheumatoid Arthritis 89 | 1,170
atypical teratoid / rhabdoid tumor 87 | 4,369
Breast cancer 85 | 3,098
Hypersensitivity reaction type II disease 84 | 235
invasive ductal carcinoma 83 | 2,950
interstitial cystitis 77 | 2,299
non-small cell lung cancer 77 | 2,798
lung adenocarcinoma 74 | 2,714
Ankylosing spondylitis 73 | 138
subependymal giant cell astrocytoma 73 | 2,287
intraductal papillary-mucinous carcinoma (IPMC) 72 | 2,988
pancreatic cancer 70 | 2,300
dermatomyositis 69 | 966
intraductal papillary-mucinous adenoma (IPMA) 69 | 2,956
Arthritis 68 | 248
malignant mesothelioma 68 | 3,163
Acquired immunodeficiency syndrome 67 | 164
ulcerative colitis 66 | 2,087
Juvenile rheumatoid arthritis 65 | 105
intraductal papillary-mucinous neoplasm (IPMN) 65 | 3,289
oligodendroglioma 65 | 2,849
Uveitis 62 | 103
pediatric high grade glioma 61 | 2,712
primitive neuroectodermal tumor 61 | 3,031
Behcet's disease 58 | 74
Human immunodeficiency virus infectious disease 57 | 129
Kidney disease 57 | 397
Carcinoma 55 | 2,147
juvenile dermatomyositis 54 | 1,189
Psoriatic arthritis 53 | 85
Multiple Sclerosis 52 | 498
tuberculosis 52 | 1,563
adult high grade glioma 51 | 2,148
Stevens-Johnson syndrome 50 | 91
group 4 medulloblastoma 50 | 1,875
Pick disease 47 | 1,893
breast carcinoma 47 | 1,614
pituitary cancer 47 | 1,972
cutaneous lupus erythematosus 46 | 1,056
ependymoma 46 | 2,514
Liver disease 45 | 219
astrocytoma 45 | 1,493
ductal carcinoma in situ 44 | 1,745
Anemia 42 | 252
Dermatitis 42 | 141
cystic fibrosis 42 | 1,670
pancreatic ductal adenocarcinoma liver metastasis 40 | 1,795
posterior fossa group A ependymoma 40 | 1,511
Alzheimer's disease 39 | 644
astrocytic glioma 39 | 2,241
primary Sjogren syndrome 39 | 788
Behcet's syndrome 37 | 50
Nephritis 37 | 63
Retinal vasculitis 36 | 36
Synovitis 36 | 72
Takayasu's arteritis 36 | 54
drug-induced hepatitis 36 | 44
Congenital adrenal hyperplasia 35 | 74
Spondyloarthropathy, Susceptibility To, 1 35 | 35
acute quadriplegic myopathy 35 | 1,157
Duchenne muscular dystrophy 33 | 602
medulloblastoma 33 | 1,524
Hepatitis B 31 | 103
colon cancer 31 | 1,475
Multiple myeloma 30 | 1,327
group 3 medulloblastoma 30 | 2,254
primary pancreatic ductal adenocarcinoma 30 | 1,271
Obesity 29 | 616
adrenocortical carcinoma 29 | 1,427
posterior fossa group B ependymoma 29 | 1,530
Leprosy 28 | 77
esophageal adenocarcinoma 28 | 737
Atherosclerosis 27 | 275
Hemochromatosis 27 | 55
Hypertension 27 | 293
Asthma 26 | 349
Skin disease 26 | 65
mucosa-associated lymphoid tissue lymphoma 26 | 480
gastric carcinoma 25 | 832
Down syndrome 23 | 548
IGA Glomerulonephritis 23 | 454
Primary immunodeficiency disease 23 | 52
spina bifida 23 | 1,064
Schizophrenia 22 | 503
active Crohn's disease 22 | 918
autosomal dominant Emery-Dreifuss muscular dystrophy 22 | 499
Birdshot chorioretinopathy 21 | 23
Coronary artery disease 21 | 240
sarcoidosis 21 | 368
Prostatic Neoplasms 20 | 471

Tissue

Endocrine System 320 | 18,511
Nervous System 320 | 18,560
Urinary Tract 320 | 18,443
Digestive Tract 319 | 18,472
Female tissues 319 | 18,646
Cardiovascular System 318 | 17,957
Liver and Pancreas 318 | 18,135
Blood and immune system 317 | 17,994
Male tissues 316 | 17,968
Respiratory system 315 | 17,483
Skin and soft tissues 309 | 18,114

Target Family

Non-IDG 270 | 11,969
Enzyme 64 | 4,146
Kinase 44 | 634
Ion Channel 8 | 341
GPCR 5 | 408
Transporter 3 | 473

Compartment GO Term

Side of membrane 394 | 394
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosine-protein kinase Fer FER Tchem Kinase -1.84299 53.1 358
ERBB receptor feedback inhibitor 1 ERRFI1 Tbio Non-IDG -1.84249 72.2 131
Folate receptor alpha FOLR1 Tchem Non-IDG -2.27944 181.4 235
Rho guanine nucleotide exchange factor 25 ARHGEF25 Tbio Non-IDG -1.42716 30.4 46
Ras/Rap GTPase-activating protein SynGAP SYNGAP1 Tbio Enzyme -1.86167 72.3 167
Ras GTPase-activating protein nGAP RASAL2 Tbio Enzyme -1.50499 28.6 91
HLA class I histocompatibility antigen, B-35 alpha chain HLA-B Tbio Non-IDG -1.87358 1568.8 0
Guanine nucleotide-binding protein subunit beta-like protein 1 GNB1L Tbio Non-IDG -1.88405 75.6 53
Serine protease HTRA2, mitochondrial HTRA2 Tbio Enzyme -2.56782 368.4 441
GTPase KRas KRAS Tbio Enzyme -3.77389 5694.2 421