Development Level

Tbio 265 | 10,625
Tchem 76 | 1,890
Tclin 34 | 602
Tdark 19 | 7,003

Collection

Eligible Ion Channel Proteins 4 | 117
Eligible non-olfactory GPCR Proteins 1 | 145

IMPC Term

preweaning lethality, complete... 16 | 633
preweaning lethality, incomple... 7 | 260
abnormal behavior 6 | 226
abnormal bone structure 6 | 131
decreased total body fat amoun... 6 | 186
abnormal bone mineralization 5 | 55
decreased bone mineral content 5 | 157
decreased body weight 4 | 174
enlarged heart 4 | 111
increased heart weight 4 | 37
decreased NK T cell number 3 | 28
decreased bone mineral density 3 | 126
decreased circulating HDL chol... 3 | 77
decreased circulating alanine ... 3 | 53
decreased circulating choleste... 3 | 85
decreased circulating triglyce... 3 | 83
decreased fasted circulating g... 3 | 49
decreased grip strength 3 | 123
hypoactivity 3 | 89
increased CD4-positive, alpha ... 3 | 15
increased bone mineral content 3 | 92
increased circulating phosphat... 3 | 24
increased fasted circulating g... 3 | 68
increased lean body mass 3 | 107
abnormal QRS complex 2 | 25
abnormal heart morphology 2 | 51
abnormal kidney morphology 2 | 30
abnormal retina morphology 2 | 100
abnormal retinal pigmentation 2 | 61
abnormal seminal vesicle morph... 2 | 47
abnormal sleep behavior 2 | 63
abnormal spleen morphology 2 | 36
corneal opacity 2 | 25
decreased T cell number 2 | 31
decreased circulating LDL chol... 2 | 37
decreased circulating calcium ... 2 | 33
decreased circulating insulin ... 2 | 75
decreased circulating phosphat... 2 | 15
decreased lean body mass 2 | 195
decreased prepulse inhibition 2 | 52
enlarged spleen 2 | 26
impaired righting response 2 | 19
increased body weight 2 | 42
increased circulating potassiu... 2 | 31
increased grip strength 2 | 83
increased hematocrit 2 | 36
increased leukocyte cell numbe... 2 | 37
increased mean corpuscular vol... 2 | 91
increased or absent threshold ... 2 | 128
male infertility 2 | 62
thrombocytopenia 2 | 46
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal gait 1 | 51
abnormal hair growth 1 | 8
abnormal liver morphology 1 | 5
abnormal lung morphology 1 | 15
abnormal rib morphology 1 | 28
abnormal testis morphology 1 | 30
abnormal vertebrae morphology 1 | 14
abnormal vocalization 1 | 21
absent pinna reflex 1 | 21
cardiovascular system phenotyp... 1 | 35
decreased body length 1 | 108
decreased circulating potassiu... 1 | 17
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased exploration in new e... 1 | 9
decreased heart weight 1 | 44
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased mean corpuscular vol... 1 | 50
decreased neutrophil cell numb... 1 | 37
embryonic lethality prior to t... 1 | 187
enlarged heart atrium 1 | 2
female infertility 1 | 34
hydrometra 1 | 13
increased NK cell number 1 | 19
increased blood urea nitrogen ... 1 | 44
increased body length 1 | 20
increased circulating HDL chol... 1 | 63
increased circulating alkaline... 1 | 119
increased circulating calcium ... 1 | 32
increased circulating chloride... 1 | 43
increased circulating creatini... 1 | 29
increased circulating sodium l... 1 | 71
increased effector memory CD4-... 1 | 15
increased erythrocyte cell num... 1 | 26
increased hemoglobin content 1 | 45
increased respiratory quotient 1 | 12
increased startle reflex 1 | 38
polycystic kidney 1 | 9
prenatal lethality 1 | 16
prenatal lethality prior to he... 1 | 64
rough coat 1 | 1
small testis 1 | 37
sparse hair 1 | 6
straub tail 1 | 26
tremors 1 | 34
vertebral fusion 1 | 23

Disease

Cancer 198 | 2,346
psoriasis 178 | 6,685
osteosarcoma 177 | 7,933
ovarian cancer 168 | 8,492
medulloblastoma, large-cell 134 | 6,234
glioblastoma 127 | 5,572
diabetes mellitus 119 | 1,663
lung cancer 110 | 4,473
lung carcinoma 101 | 2,844
pilocytic astrocytoma 92 | 3,086
Rheumatoid Arthritis 89 | 1,171
atypical teratoid / rhabdoid tumor 87 | 4,369
Breast cancer 85 | 3,099
Hypersensitivity reaction type II disease 84 | 235
invasive ductal carcinoma 83 | 2,950
interstitial cystitis 77 | 2,299
non-small cell lung cancer 77 | 2,798
lung adenocarcinoma 74 | 2,714
Ankylosing spondylitis 73 | 138
subependymal giant cell astrocytoma 73 | 2,287
intraductal papillary-mucinous carcinoma (IPMC) 72 | 2,988
pancreatic cancer 70 | 2,300
dermatomyositis 69 | 967
intraductal papillary-mucinous adenoma (IPMA) 69 | 2,956
Arthritis 68 | 248
malignant mesothelioma 68 | 3,163
Acquired immunodeficiency syndrome 67 | 164
ulcerative colitis 66 | 2,087
Juvenile rheumatoid arthritis 65 | 105
intraductal papillary-mucinous neoplasm (IPMN) 65 | 3,289
oligodendroglioma 65 | 2,849
Uveitis 62 | 103
pediatric high grade glioma 61 | 2,712
primitive neuroectodermal tumor 61 | 3,031
Behcet's disease 58 | 74
Human immunodeficiency virus infectious disease 57 | 129
Kidney disease 57 | 397
Carcinoma 55 | 2,147
juvenile dermatomyositis 54 | 1,189
Psoriatic arthritis 53 | 85
Multiple Sclerosis 52 | 498
tuberculosis 52 | 1,563
adult high grade glioma 51 | 2,148
Stevens-Johnson syndrome 50 | 91
group 4 medulloblastoma 50 | 1,875
Pick disease 47 | 1,893
breast carcinoma 47 | 1,614
pituitary cancer 47 | 1,972
cutaneous lupus erythematosus 46 | 1,056
ependymoma 46 | 2,514
Liver disease 45 | 219
astrocytoma 45 | 1,493
ductal carcinoma in situ 44 | 1,745
Anemia 42 | 252
Dermatitis 42 | 141
cystic fibrosis 42 | 1,670
pancreatic ductal adenocarcinoma liver metastasis 40 | 1,795
posterior fossa group A ependymoma 40 | 1,511
Alzheimer's disease 39 | 644
astrocytic glioma 39 | 2,241
primary Sjogren syndrome 39 | 789
Behcet's syndrome 37 | 50
Nephritis 37 | 63
Retinal vasculitis 36 | 36
Synovitis 36 | 72
Takayasu's arteritis 36 | 54
drug-induced hepatitis 36 | 44
Congenital adrenal hyperplasia 35 | 74
Spondyloarthropathy, Susceptibility To, 1 35 | 35
acute quadriplegic myopathy 35 | 1,157
Duchenne muscular dystrophy 33 | 602
medulloblastoma 33 | 1,524
Hepatitis B 31 | 103
colon cancer 31 | 1,475
Multiple myeloma 30 | 1,328
group 3 medulloblastoma 30 | 2,254
primary pancreatic ductal adenocarcinoma 30 | 1,271
Obesity 29 | 616
adrenocortical carcinoma 29 | 1,427
posterior fossa group B ependymoma 29 | 1,530
Leprosy 28 | 77
esophageal adenocarcinoma 28 | 737
Atherosclerosis 27 | 275
Hemochromatosis 27 | 55
Hypertension 27 | 293
Asthma 26 | 349
Skin disease 26 | 65
mucosa-associated lymphoid tissue lymphoma 26 | 480
gastric carcinoma 25 | 832
Down syndrome 23 | 548
IGA Glomerulonephritis 23 | 454
Primary immunodeficiency disease 23 | 52
spina bifida 23 | 1,064
Schizophrenia 22 | 503
active Crohn's disease 22 | 918
autosomal dominant Emery-Dreifuss muscular dystrophy 22 | 499
Birdshot chorioretinopathy 21 | 23
Coronary artery disease 21 | 240
sarcoidosis 21 | 368
Prostatic Neoplasms 20 | 471

Tissue

Endocrine System 320 | 18,512
Nervous System 320 | 18,561
Urinary Tract 320 | 18,444
Digestive Tract 319 | 18,473
Female tissues 319 | 18,647
Cardiovascular System 318 | 17,958
Liver and Pancreas 318 | 18,136
Blood and immune system 317 | 17,995
Male tissues 316 | 17,969
Respiratory system 315 | 17,484
Skin and soft tissues 309 | 18,115

Target Family

Non-IDG 270 | 11,969
Enzyme 64 | 4,146
Kinase 44 | 634
Ion Channel 8 | 341
GPCR 5 | 408
Transporter 3 | 473

Compartment GO Term

Side of membrane 394 | 394
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, alpha chain G HLA-G Tbio Non-IDG -3.07995 1275.9 729
Exocyst complex component 1 EXOC1 Tbio Non-IDG -1.83471 76.2 50
Synembryn-B RIC8B Tbio Non-IDG -1.63259 43.4 37
Guanine nucleotide-binding protein subunit alpha-15 GNA15 Tbio Non-IDG -2.74618 475.0 155
CD276 antigen CD276 Tbio Non-IDG -3.01052 733.9 392
TNF receptor-associated factor 6 TRAF6 Tbio Non-IDG -2.67984 438.1 349
Migration and invasion enhancer 1 MIEN1 Tbio Non-IDG -1.26825 19.6 155
HLA class II histocompatibility antigen, DP beta 1 chain HLA-DPB1 Tbio Non-IDG -2.67719 572.7 274
Tyrosine-protein phosphatase non-receptor type 22 PTPN22 Tchem Enzyme -2.68153 504.5 190
HLA class I histocompatibility antigen, A-3 alpha chain HLA-A Tbio Non-IDG -2.40709 4042.7 585