Development Level

Tbio 17 | 11,445
Tchem 3 | 1,598
Tdark 3 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal embryo size 2 | 220
embryonic lethality prior to o... 2 | 239
abnormal behavior 1 | 298
abnormal pericardium morpholog... 1 | 26
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased leukocyte cell numbe... 1 | 73
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
enlarged spleen 1 | 41
increased bone mineral density 1 | 72
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 17 | 11,493
psoriasis 11 | 6,694
osteosarcoma 10 | 7,950
ovarian cancer 9 | 8,520
Cancer 8 | 2,499
Kabuki syndrome 7 | 27
Kidney cancer 7 | 2,613
Breast cancer 5 | 3,578
glioblastoma 5 | 5,792
group 3 medulloblastoma 5 | 4,104
Intellectual disability 4 | 1,016
atypical teratoid / rhabdoid tumor 4 | 5,112
medulloblastoma, large-cell 4 | 6,241
Bladder Neoplasm 3 | 112
Cleft Palate 3 | 271
Dull intelligence 3 | 645
Endometrial cancer 3 | 311
Esophageal Squamous Cell Carcinoma 3 | 77
Failure to gain weight 3 | 365
Liver cancer 3 | 604
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Muscle hypotonia 3 | 571
Pediatric failure to thrive 3 | 365
Poor school performance 3 | 645
Short stature 3 | 531
Small head 3 | 374
Squamous cell carcinoma of esophagus 3 | 77
Urinary Bladder Neoplasms 3 | 114
pancreatic cancer 3 | 2,398
spina bifida 3 | 1,074
Acquired scoliosis 2 | 281
Adenoid Cystic Carcinoma 2 | 99
Anemia, Hemolytic 2 | 55
Arrhythmogenic right ventricular cardiomyopathy 2 | 30
Atrial Septal Defects 2 | 85
Autoimmune thrombocytopenia 2 | 22
Birthmark 2 | 35
Blepharoptosis 2 | 231
Blue sclera 2 | 32
Bowed and upward slanting eyebrows 2 | 41
Broad flat nasal bridge 2 | 236
Byzanthine arch palate 2 | 194
Cafe-au-Lait Spots 2 | 37
Carcinoma, Adenoid Cystic 2 | 99
Carcinoma, Hepatocellular 2 | 228
Carcinoma, Transitional Cell 2 | 32
Cerebral atrophy 2 | 178
Conductive hearing loss 2 | 123
Congenital deafness 2 | 185
Congenital hemivertebra 2 | 25
Curvature of spine 2 | 282
DOID:2627 2 | 94
Deafness 2 | 198
Decreased size of teeth 2 | 62
Decreased width of tooth 2 | 59
Dental abnormalities 2 | 60
Depressed nasal tip 2 | 11
Dilated ventricles (finding) 2 | 121
Hearing Loss, Partial 2 | 185
Hip Dislocation, Congenital 2 | 48
Hirsutism 2 | 47
Hypodontia 2 | 81
Idiopathic thrombocytopenia 2 | 22
Immune thrombocytopenic purpura 2 | 24
Joint hyperflexibility 2 | 78
Large auricle 2 | 87
Large dysplastic ears 2 | 87
Large pinnae 2 | 87
Large prominent ears 2 | 87
Large protruding ears 2 | 87
Large, floppy ears 2 | 87
Liver carcinoma 2 | 240
Long eyelashes 2 | 37
Lymphoid leukemia 2 | 160
Macrotia 2 | 87
Malabsorption 2 | 82
Microdontia (disorder) 2 | 59
Nasal bridge wide 2 | 236
Obstruction of pelviureteric junction 2 | 8
Posteriorly rotated ear 2 | 61
Preauricular Fistulae, Congenital 2 | 27
Preauricular dimple 2 | 27
Preauricular sinus 2 | 27
Prominent ear 2 | 56
Protruding ears 2 | 56
Range of joint movement increased 2 | 32
Recurrent aspiration pneumonia 2 | 4
Recurrent infections 2 | 48
Recurrent otitis media 2 | 42
Seizures 2 | 596
Sensorineural Hearing Loss (disorder) 2 | 284
Sezary Syndrome 2 | 27
Sparse eyebrow 2 | 42
Strabismus 2 | 270
Thick, flared eyebrows 2 | 41
Tooth Abnormalities 2 | 69
Widely spaced teeth 2 | 31
hearing impairment 2 | 199

Tissue

Endocrine System 23 | 18,159
Blood and immune system 22 | 16,909
Female tissues 22 | 17,400
Skin and soft tissues 22 | 17,230
Digestive Tract 21 | 17,369
Male tissues 21 | 17,142
Nervous System 21 | 16,725
Respiratory system 21 | 16,393
Liver and Pancreas 20 | 16,750
Urinary Tract 20 | 16,678
Cardiovascular System 19 | 15,192

Target Family

Non-IDG 13 | 12,091
Epigenetic 8 | 242
Enzyme 2 | 4,145

Compartment GO Term

Set1C/COMPASS complex 23 | 23
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DPY30 domain-containing protein 1 DYDC1 Tbio Non-IDG -0.70377 5.09 133
Histone-lysine N-methyltransferase SETD1A SETD1A Tbio Epigenetic -2.57679 365.2 125
Histone-lysine N-methyltransferase 2B KMT2B Tbio Epigenetic -1.93899 84.8 153
Lysine-specific demethylase 6A KDM6A Tchem Epigenetic -2.27999 176.8 119
WD repeat-containing protein 87 WDR87 Tdark Non-IDG 0.42 0.25 13
Histone-lysine N-methyltransferase SETD1B SETD1B Tbio Epigenetic -1.30968 18.7 90
Histone-lysine N-methyltransferase, H3 lysine-79 specific DOT1L Tchem Epigenetic -2.29797 199.6 330
Retinoblastoma-binding protein 5 RBBP5 Tbio Non-IDG -1.40059 20.2 180
Set1/Ash2 histone methyltransferase complex subunit ASH2 ASH2L Tbio Enzyme -1.56543 33.7 261
Histone-lysine N-methyltransferase 2C KMT2C Tbio Epigenetic -1.87625 76.5 68