Development Level

Tbio 293 | 10,625
Tchem 73 | 1,890
Tdark 44 | 7,003
Tclin 21 | 602

Collection

Kinase: IDG Consortium (Targets) 2 | 125
Kinase: IDG Consortium (Complete/Control) 1 | 37

IMPC Phenotype

preweaning lethality, complete... 13 | 633
abnormal behavior 11 | 226
decreased grip strength 9 | 123
decreased lean body mass 8 | 195
preweaning lethality, incomple... 8 | 260
decreased bone mineral content 7 | 157
hypoactivity 7 | 89
decreased total body fat amoun... 6 | 186
embryonic lethality prior to t... 6 | 187
increased or absent threshold ... 6 | 128
decreased body length 5 | 108
decreased circulating insulin ... 5 | 75
enlarged heart 5 | 111
abnormal coat-hair pigmentatio... 4 | 54
decreased circulating HDL chol... 4 | 77
decreased vertical activity 4 | 22
increased bone mineral content 4 | 92
increased circulating sodium l... 4 | 71
increased total body fat amoun... 4 | 57
short tibia 4 | 82
abnormal QRS complex 3 | 25
abnormal behavioral response t... 3 | 52
abnormal bone structure 3 | 131
abnormal embryo size 3 | 112
abnormal epididymis morphology 3 | 31
abnormal lens morphology 3 | 73
abnormal retinal blood vessel ... 3 | 18
abnormal retinal pigmentation 3 | 61
cataract 3 | 26
decreased circulating LDL chol... 3 | 37
decreased circulating choleste... 3 | 85
decreased circulating glucose ... 3 | 121
decreased fasted circulating g... 3 | 49
decreased heart weight 3 | 44
hyperactivity 3 | 108
increased erythrocyte cell num... 3 | 26
increased grip strength 3 | 83
increased hematocrit 3 | 36
increased hemoglobin content 3 | 45
male infertility 3 | 62
thrombocytopenia 3 | 46
abnormal humerus morphology 2 | 11
abnormal kidney morphology 2 | 30
abnormal locomotor activation 2 | 26
abnormal neural tube closure 2 | 37
abnormal retina morphology 2 | 100
abnormal seminal vesicle morph... 2 | 47
abnormal sleep behavior 2 | 63
abnormal testis morphology 2 | 30
abnormal tooth morphology 2 | 24
decreased body weight 2 | 174
decreased bone mineral density 2 | 126
decreased circulating bilirubi... 2 | 14
decreased circulating serum al... 2 | 79
decreased circulating triglyce... 2 | 83
decreased effector memory CD8-... 2 | 24
decreased eosinophil cell numb... 2 | 41
decreased hemoglobin content 2 | 53
decreased mean corpuscular hem... 2 | 34
decreased mean corpuscular hem... 2 | 19
decreased neutrophil cell numb... 2 | 37
embryonic lethality prior to o... 2 | 148
enlarged epididymis 2 | 27
hemorrhage 2 | 12
immune system phenotype 2 | 17
improved glucose tolerance 2 | 56
increased blood urea nitrogen ... 2 | 44
increased body weight 2 | 42
increased circulating serum al... 2 | 25
increased lean body mass 2 | 107
increased mean corpuscular hem... 2 | 93
increased mean corpuscular hem... 2 | 25
increased startle reflex 2 | 38
persistence of hyaloid vascula... 2 | 22
tremors 2 | 34
abnormal coping response 1 | 12
abnormal heart morphology 1 | 51
abnormal respiratory quotient 1 | 9
abnormal rib morphology 1 | 28
abnormal skin morphology 1 | 23
abnormal snout morphology 1 | 18
decreased NK cell number 1 | 16
decreased blood urea nitrogen ... 1 | 31
decreased circulating chloride... 1 | 32
decreased exploration in new e... 1 | 9
decreased gamma-delta T cell n... 1 | 18
embryonic growth retardation 1 | 28
hydrops fetalis 1 | 22
impaired righting response 1 | 19
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating magnesiu... 1 | 10
increased circulating triglyce... 1 | 24
increased rib number 1 | 41
limb grasping 1 | 35
oligodactyly 1 | 14
premature death 1 | 5
prenatal lethality prior to he... 1 | 64
stereotypic behavior 1 | 3
trunk curl 1 | 15

Disease

psoriasis 190 | 6,685
osteosarcoma 185 | 7,933
ovarian cancer 181 | 8,491
glioblastoma 165 | 5,572
medulloblastoma, large-cell 161 | 6,234
pilocytic astrocytoma 130 | 3,086
lung carcinoma 123 | 2,844
lung cancer 122 | 4,473
Cancer 120 | 2,346
atypical teratoid / rhabdoid tumor 118 | 4,369
oligodendroglioma 111 | 2,849
intraductal papillary-mucinous adenoma (IPMA) 109 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 102 | 3,289
pediatric high grade glioma 102 | 2,712
intraductal papillary-mucinous carcinoma (IPMC) 94 | 2,988
malignant mesothelioma 93 | 3,163
invasive ductal carcinoma 92 | 2,950
pancreatic cancer 91 | 2,300
diabetes mellitus 89 | 1,663
primitive neuroectodermal tumor 87 | 3,031
lung adenocarcinoma 84 | 2,714
subependymal giant cell astrocytoma 76 | 2,287
Pick disease 71 | 1,893
astrocytoma 70 | 1,493
ependymoma 70 | 2,514
non-small cell lung cancer 70 | 2,798
Breast cancer 69 | 3,098
Carcinoma 67 | 2,147
ulcerative colitis 66 | 2,087
interstitial cystitis 63 | 2,299
Alzheimer's disease 58 | 644
astrocytic glioma 58 | 2,241
pituitary cancer 57 | 1,972
posterior fossa group A ependymoma 57 | 1,511
cystic fibrosis 56 | 1,670
group 4 medulloblastoma 53 | 1,875
ductal carcinoma in situ 52 | 1,745
tuberculosis 52 | 1,563
adult high grade glioma 50 | 2,148
colon cancer 50 | 1,475
group 3 medulloblastoma 50 | 2,254
Obesity 47 | 616
pancreatic ductal adenocarcinoma liver metastasis 46 | 1,795
posterior fossa group B ependymoma 46 | 1,530
Kidney disease 44 | 397
primary pancreatic ductal adenocarcinoma 44 | 1,271
medulloblastoma 41 | 1,524
adrenocortical carcinoma 40 | 1,427
Cerebrovascular disease 39 | 231
sonic hedgehog group medulloblastoma 39 | 1,482
Hypertension 38 | 293
Multiple myeloma 38 | 1,327
Schizophrenia 38 | 503
breast carcinoma 38 | 1,614
Atherosclerosis 35 | 275
Asthma 34 | 349
Atopic dermatitis 34 | 944
Duchenne muscular dystrophy 34 | 602
cutaneous lupus erythematosus 34 | 1,056
Parkinson's disease 33 | 364
gastric carcinoma 33 | 832
mucosa-associated lymphoid tissue lymphoma 33 | 480
Diarrhea 32 | 155
atypical teratoid/rhabdoid tumor 32 | 1,095
esophageal adenocarcinoma 32 | 737
juvenile dermatomyositis 32 | 1,189
Heart disease 31 | 279
Coronary artery disease 30 | 240
Epilepsy 29 | 346
Rheumatoid Arthritis 29 | 1,170
pancreatic carcinoma 29 | 567
Waldenstrons macroglobulinemia 28 | 764
Endometriosis 27 | 535
Neurodegenerative disease 26 | 383
Arthritis 25 | 248
Lung disease 25 | 136
Prostatic Neoplasms 25 | 471
dermatomyositis 25 | 966
nasopharyngeal carcinoma 25 | 1,056
spina bifida 25 | 1,064
Adenoma 24 | 165
Dementia 24 | 129
Down syndrome 24 | 548
Hypertensive disease 24 | 193
active Crohn's disease 24 | 918
acute quadriplegic myopathy 24 | 1,157
Autistic Disorder 23 | 320
Liver disease 23 | 219
Pancreatitis 23 | 97
Hypoglycemia 22 | 81
Tetanus 22 | 66
Vascular disease 22 | 281
Anemia 21 | 252
Toxic encephalopathy 21 | 131
gastric cancer 21 | 436
non primary Sjogren syndrome sicca 21 | 840
Neuropathy 20 | 210
Polycystic Ovary Syndrome 20 | 334
fibroadenoma 20 | 557
Osteoporosis 19 | 259

Tissue

Endocrine System 426 | 18,511
Female tissues 425 | 18,646
Nervous System 425 | 18,560
Digestive Tract 424 | 18,472
Skin and soft tissues 424 | 18,114
Urinary Tract 422 | 18,443
Liver and Pancreas 419 | 18,135
Blood and immune system 415 | 17,994
Cardiovascular System 415 | 17,957
Male tissues 413 | 17,968
Respiratory system 406 | 17,483

Target Family

Non-IDG 297 | 11,969
Enzyme 94 | 4,146
Transporter 22 | 473
Ion Channel 6 | 341
Kinase 5 | 634
GPCR 4 | 408
Epigenetic 1 | 242
TF/Epigenetic 1 | 38
Transcription Factor 1 | 1,400

Compartment GO Term

Secretory vesicle 431 | 431
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alpha-soluble NSF attachment protein NAPA Tbio Non-IDG -1.91708 86.7 133
Alpha-1-antichymotrypsin SERPINA3 Tchem Non-IDG -2.94207 803.8 261
Alpha-1-antitrypsin SERPINA1 Tbio Non-IDG -3.73976 5495.0 809
Alpha-2-macroglobulin A2M Tbio Non-IDG -2.95602 802.7 553
Maltase-glucoamylase, intestinal MGAM Tclin Enzyme -4.50018 27956.4 30
Metalloproteinase inhibitor 1 TIMP1 Tbio Enzyme -3.55219 3513.4 673
Centrosomal protein of 131 kDa CEP131 Tbio Non-IDG -1.75708 61.0 81
Testis-specific serine/threonine-protein kinase 1 TSSK1B Tchem Kinase -1.41882 23.1 26
Pro-epidermal growth factor EGF Tbio Non-IDG -3.74596 4837.7 851
Hepatocyte growth factor HGF Tchem Enzyme -3.29371 2317.3 573